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Featured Publications

Our faculty actively engage in groundbreaking research and have published widely in leading peer-reviewed journals. Below is a selection of their recent accomplishments.


Major Extremity Trauma Research Consortium (METRC). Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture. 

N Engl J Med. 2023;388(3):203-213. 


Slobogean GP, Sprague S, Wells JL, et al. Aqueous skin antisepsis before surgical fixation of open fractures (Aqueous-PREP): a multiple-period, cluster-randomised, crossover trial. 

The Lancet. 2022;400(10360):1334-1344. 


METRC, O’Toole RV, Joshi M, et al. Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial. 

JAMA Surg. 2021;156(5):e207259.

JAMA Invited Commentary

O’Hara NN. Eliciting Health Care Preferences with Discrete Choice Experiments. 

JAMA Netw Open. 2022;5(4):e228794. 


METRC. Effect of Supplemental Perioperative Oxygen on SSI Among Adults with Lower-Extremity Fractures at Increased Risk for Infection: A Randomized Clinical Trial. 

Journal of Bone and Joint Surgery. 2022;104(14):1236-1243.


O’Toole RV, Gary JL, Reider L, et al. A Prospective Randomized Trial to Assess Fixation Strategies for Severe Open Tibia Fractures: Modern Ring External Fixators Versus Internal Fixation (FIXIT Study). 

Journal of Orthopaedic Trauma. 2017;31(1):S10-S17. 


Slobogean GP, Gaski G, Nascone J, et al. A Prospective Clinical Trial Comparing Surgical Fixation versus Nonoperative Management of Minimally Displaced Complete Lateral Compression Pelvis Fractures. 

Journal of Orthopaedic Trauma. 2021;Publish Ahead of Print. 


Manson TT, Slobogean GP, Nascone JW, et al. Open reduction and internal fixation alone versus open reduction and internal fixation plus total hip arthroplasty for displaced acetabular fractures in patients older than 60 years: A prospective clinical trial. 

Injury. 2022;53(2):523-528. 


Slobogean GP, Sprague S, Bzovsky S, et al. Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Clinical Outcomes of a Multicenter 2 × 2 Factorial Randomized Controlled Pilot Trial in Young Femoral Neck Fracture Patients. 

Journal of Orthopaedic Trauma. 2020;34(10):524-532.