August 13, 2019 | Joanne Morrison
Department of Anesthesiology
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University of Maryland School of Medicine
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Thursday, July 28, 2022
Researchers Discover One of the Largest Known Bacteria-to-Animal Gene Transfer Inside a Fruit Fly
A fruit fly genome is not a just made up of fruit fly DNA – at least for one fruit fly species. New research from the University of Maryland School of Medicine’s (UMSOM) Institute for Genome Sciences (IGS) shows that one fruit fly species contains whole genomes of a kind of bacteria, making this finding the largest bacteria-to-animal transfer of genetic material ever discovered. The new research also sheds light on how this happens.
Monday, September 20, 2021
UM School of Medicine Receives $7.5 Million Grant to Create Complex Model of Female Reproductive Tract to Study Infections
Researchers at the Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine have received a $7.5 million federal grant to create a complex model of the female reproductive system in order to study sexually transmitted infections (STIs). They plan to create a realistic 3D model that integrates vaginal and cervical epithelial cells and the bacteria that colonize these cells, called a microbiome. They aim to use this model to identity factors that play a role in chlamydia and gonorrhea infections experienced by a growing number of women in the U.S. and worldwide.
Thursday, March 18, 2021
UM School of Medicine Helps Maryland Conduct State-Wide Sequencing of Variants in Positive COVID-19 Test Specimens
In an effort to monitor the spread of COVID-19 variants in the State of Maryland, University of Maryland School of Medicine (UMSOM) Dean E. Albert Reece, MD, PhD, MBA, announced that UMaryland Genomics at UMSOM will perform genome sequencing of variants in at least 10 percent of COVID-19 test samples, reaching an important benchmark set by the federal government to help control the spread of these variants.
Tuesday, December 03, 2019
UM School of Medicine Researchers Institute for Genome Sciences' Researchers Discover Potential New Treatment for Tropical Parasitic Disease Using Genomics
Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine (UMSOM) Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat. The potential new therapy is an experimental cancer drug called JQ1 and targets proteins found prominently in the worm’s genome; it appears to effectively kill the adult worms in a laboratory setting, according to the study which was published today in the journal mSystems.
Friday, October 18, 2019
Diabetes Worsens Respiratory Illness Due to Abnormal Immune Response, UM School of Medicine Study Finds
Since the Middle East respiratory syndrome coronavirus (MERS-CoV) first emerged in Saudi Arabia in 2012, there have been more than 2,400 confirmed cases of the infection, resulting in greater than 800 deaths – an alarming fatality rate of 35 percent. For this reason, researchers have been eager to identify any risk factors that contribute to the development of severe or lethal disease. Current clinical evidence points to diabetes as a major risk factor in addition to other comorbidities including kidney disease, heart disease, and lung disease.
Thursday, April 04, 2019
UM School of Medicine's Institute for Genome Sciences Awarded $17.5 Million Grant for Infectious Disease Research
The Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) was awarded $17.5 million from the National Institute of Allergy and Infectious Diseases (NIAID) to fund the IGS Genome Center for Infectious Diseases (GCID) for another five years.
Wednesday, March 27, 2019
New Study Finds That Bacteria and Immunity in the Cervix May be Key to Predicting Premature Birth
Spontaneous preterm birth (sPTB), defined as birth before 37 weeks of gestation, and the related complications, are the largest contributors to infant death in the United States and worldwide, according to the World Health Organization. Researchers at the University of Maryland School of Medicine (UMSOM) have discovered that bacteria and innate immune factors in a woman’s birth canal and cervix may increase the risk of spontaneous preterm birth or provide protection against such births.
Tuesday, February 12, 2019
UMSOM Scientists Call for Unrestricted Usage of Public Genome Data
Researchers at the Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) called for open access to genome data, stating that unrestricted usage is needed for progress in combating the world’s most serious diseases.
Friday, February 08, 2019
University of Maryland School of Medicine Genome Scientists Develop Novel Approaches to Studying the Most Widespread Form of Malaria
Scientists at the Institute of Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria.
Thursday, September 27, 2018
University of Maryland School of Medicine Scientist Receives Prestigious Microbiome Award
Owen White, PhD, professor of epidemiology and public health, and Associate Director for Informatics at the Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM), has received the 2018 Microbiome Pioneer Award. The prestigious honor is part of the Bioinformatics for the Microbiome Symposium organized by Stanford University. The microbiome is the name given collectively to the community of trillions of microbial organisms that live on and within our bodies.
Friday, September 14, 2018
Nationwide Research on African-American Kidneys Hopes to Unravel Genetic Variation That Increases Disease Risk
With African-Americans developing kidney failure at rates four to five times higher than Americans of European descent, a groundbreaking nationwide study will track nearly every African-American donor kidney over the next five years.
Monday, May 14, 2018
New Research: Some Gut Bacteria May Protect Against Intestinal Infection
Scientists at the University of Maryland School of Medicine (UMSOM) have for the first time found evidence that the presence of a key species in the human gut microbiome is associated with protection from infection with typhoid fever. If the research is borne out, it could offer an exciting new way to reduce intestinal infections from microbes.
Thursday, March 22, 2018
With Big Data, Researchers Identify New Targets for Lung Disease Treatments
Every year, approximately 12 million adults in the U.S. are diagnosed with Chronic Obstructive Pulmonary Disease (COPD), and 120,000 die from it. For people with COPD, Haemophilus influenzae, a bacterium, can be particularly dangerous.
Tuesday, December 19, 2017
UMSOM Scientists Identify Key Factors that Help Microbes Thrive in Harsh Environments
Three new studies by University of Maryland School of Medicine (UMSOM) scientists have identified key factors that help microbes survive in harsh environments.
Wednesday, May 25, 2016
UMSOM Researchers Develop New Way to Decode Large Amounts of Biological Data
A University of Maryland School of Medicine researcher has helped develop an innovative computing technique that, on very large amounts of data, is both faster and more accurate than current methods. To spur research, a program using this technique is being offered for free to the biomedical research community.