Dr. Peixin Yang Research
Center for Birth Defects Research
Summary of Research
Dr. Yang’s research focuses on the molecular mechanism(s) and potential therapeutic approaches of maternal diabetes-induced neural tube defects and cardiovascular defects in the offspring.
His laboratory has made original and significant contributions to the area of maternal diabetes-induced structural birth defects, particularly delineating the molecular mechanism(s) underlying neural tube defects and heart defects and revealing the therapeutic potential of several naturally occurring compounds.
Research Interests
- Decoding the Oxidative Stress Hypothesis in Diabetic Embryopathy through Apoptotic Kinase Signaling
- Unraveling the Molecular Intermediates Upstream and Downstream JNK1/2
- Revealing Cellular Organelle Stress as one of the Cause of Diabetic Embryopathy
- Developing Natural Compounds as Prevention for Diabetic Embryopathy
- Elucidating High Glucose as a Teratogen
- Establishing a Type 2 Diabetic Embryopathy Model
- Discovering the Epigenetic Mechanism in Diabetic Embryopathy
- Uncovering the Molecular Mechanism Underlying Maternal Diabetes-Induced Heart Defect
Meet Our Team
Peixin Yang, PhD
Professor, Obstetrics, Gynecology and Reproductive Sciences
Division Director, Center for the Study of Birth Defects;
Deputy Director, Graduate & Post-Doctoral Studies;
Vice Chair for Research
Wei-Bin Shen, PhD
Assistant Professor,
Obstetrics, Gynecology and Reproductive Sciences
wbshen@som.umaryland.edu
Bingbing Wang, PhD
Assistant Professor,
Obstetrics, Gynecology and Reproductive Sciences
bwang@som.umaryland.edu