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Alan Faden, MD

Alan I. Faden, MD is the David S. Brown Professor in Trauma in the Department of Anesthesiology and Director of the Shock, Trauma and Anesthesiology Research Organized Research Center (STAR-ORC). STAR-ORC serves as a research umbrella for the Department of Anesthesiology and the Program in Trauma. Within the Center, Dr. Faden’s laboratory uses a multidisciplinary approach to study mechanisms of cell death and recovery following injury. It includes five faculty level investigators, nine post-doctoral fellows, five research assistants, and varying numbers of students. There are multiple collaborative programs with other academic faculties, federal research labs, and industry.

The lab uses multi-disciplinary approaches, including molecular and cellular biology, animal modeling, behavior, imaging, and drug discovery, to examine the pathobiology of experimental brain and spinal cord injury and their treatment. Specific research foci include cell cycle pathways, microglial activation, cell death pathways, metabotropic glutamate receptors, and use of combination and multifunctional drug treatment strategies for neurotrauma.  This necessitates the use of a diverse array of in vitro and in vivo models to address experimental questions.