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Mark J. Zakhary, PhD

Academic Title:

Assistant Professor

Primary Appointment:

Radiation Oncology

Phone (Primary):


Education and Training

The Johns Hopkins University, BS, Physics, 2008

Brandeis University, PhD, Physics, 2014

Mayo Clinic, Medical Physics Fellowship, 2018


Dr. Zakhary completed his Ph.D. in physics 2014 at Brandeis University in Waltham, MA. His interdiscplinary research focused on multimodality imaging of the rod-like bacteriophage virus fd, which self-assembles into novel low-dimensional materials with rich liquid crystalline properties. Dr. Zakhary then transitioned into radiation oncology and completed his medical physics fellowship at the Mayo Clinic in Rochester, MN from 2015 to 2018. During his fellowship program, Dr. Zakhary continued to focus his research on imaging, and participated in clinical trials invesitgating the use of the amino acid PET tracer 18F-DOPA for glioma imaging in both the neurosurgical and radiotherapy settings. Dr. Zakhary joined the Medical Physics team at the Maryland Proton Treatment Center in 2018. 

Research/Clinical Keywords

Proton Radiotherapy, Multimodality Imaging, Deep Tissue Thermal Therapy, Treatment Planning

Highlighted Publications

  1. Deufel, C., Dahl, R., Mullins, J., Zakhary, M. J. “A quality assurance device for measuring afterloader performance and transit dose for nasobiliary HDR brachytherapy.” Brachytherapy18, S1538-4721 (2018)
  2. Siavashpouri, M., Wachauf, C.H., Zakhary, M. J., Praetorius, F., Dietz, H., and Dogic, Z. "Molecular engineering of chiral colloidal liquid crystals using DNA origami." Nature Materials 16, 849-856 (2017)
  3. Zakhary, M. J. ,  Gibaud , T., Kaplan, C. N., Barry, E., Oldenbourg, R., Meyer, R. B., and Dogic, Z. Imprintable membranes from incomplete chiral coalescence. Nature Communications 5, 3063 (2014)
  4. Zakhary, M. J.,  Sharma, P., Ward, A., Yardimici, S. and Dogic, Z. Geometrical edgeactants control interfacial bending rigidity of colloidal membranes. Soft Matter 9, 8306-8313 (2013).
  5. Gibaud, T., Barry, E., Zakhary, M. J. et. al. Reconfigurable self-assembly through chiral control of interfacial tension. Nature 481,348-351 (2012) 

Additional Publication Citations

  1. Jia, L. L., Zakhary, M. J., Dogic, Z., Pelcovits, R. A., and Powers, T. R. "Chiral edge fluctuations of colloidal membranes." Physical Review E 95, 060701 (2017)
  2. Gibaud, T., Kaplan, C.N., Sharma, P., Zakhary, M.J., Ward, A., Oldenbourg, R., Meyer, R.B., Kamien, R.D., Powers, T.R. and Dogic, Z. "Achiral symmetry breaking and positive Gaussian modulus lead to scalloped colloidal membranes." Proceedings of the National Academy of Sciences 114, E3376-E3384 (2017)
  3. Dogic, Z., Sharma, P. and Zakhary, M. J.,  Hypercomplex Liquid Crystals. Annual Reviews of Condensed Matter Physics. 5, 137-157 (2014)

Awards and Affiliations

American Association of Physicists in Medicine

American Society for Radiation Oncology

American Brachytherapy Society

Best in Physics Award, AAPM Annual Meeting 2017

NSF Integrative Graduate Education and Research Traineeship (IGERT) Fellowship