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Michael E. Kallen, MD

Academic Title:

Associate Professor

Primary Appointment:


Administrative Title:

Associate Director of the Pathology Residency Program

Additional Title:

Director, Immunohistochemistry Laboratory



Phone (Primary):


Phone (Secondary):




Education and Training

Surgical Pathology Assistant - Johns Hopkins Hospital. July 2017 – June 2018.

Clinical Fellow – Hematopathology. National Institutes of Health / National Cancer Institute. July 2015 – June 2017.

Chief Resident - Anatomic and Clinical Pathology.  David Geffen School of Medicine, University of California Los Angeles.  July 2014 - June 2015.

Resident – Anatomic and Clinical Pathology. David Geffen School of Medicine, University of California Los Angeles. July 2011 – June 2015.

MD – Vanderbilt University School of Medicine. 2007 - 2011.

BS – Chemical Biology. University of California Berkeley. 2003 – 2007.

Research/Clinical Keywords

Sarcoma, leukemia, lymphoma, myelodysplastic syndrome

Highlighted Publications

Kline K, Chen W, Kallen ME, Koka R, Omili D, Fan X, Iraguha T, Gebru E, Dishanthan N, Baker JM, Dietze KA, Yared JA, Hankey K, Dahiya S, Niederhaus SV, Dunleavy K, Hardy NM, Luetkens T, Rapoport AP, Atanackovic D. Chimeric antigen receptor (CAR) T cells for the treatment of a kidney transplant patient with post-transplant lymphoproliferative disorder (PTLD). Hum Vaccin Immunother. 2023 Aug 1;19(2):2216116. doi: 10.1080/21645515.2023.2216116. Epub 2023 Jun 6. PMID: 37278257; PMCID: PMC10305491.

Kallen ME, Michal M, Meyer A, Suster DI, Olson NJ, Charville GW, Perret R, Gross JM. Calcified Chondroid Mesenchymal Neoplasm: Exploring the Morphologic and Clinical Features of an Emergent Entity With a Series of 33 Cases. Am J Surg Pathol. 2023 Jun 1;47(6):725-737. doi: 10.1097/PAS.0000000000002044. Epub 2023 Apr 27. PMID: 37102574.

Legesse TB, Twaddell WS, Ng VY, Davis DL, Ciner AT, Kallen ME. Anaplastic Kaposi sarcoma. Histopathology. 2023 Jul;83(1):149-150. doi: 10.1111/his.14914. Epub 2023 Apr 11. PMID: 37040901.

De La Hoz A, Koka R, Singh ZN, Law JY, Yared JA, Hornyak TJ, Kallen ME.  Trouble afoot: Mycosis fungoides bullosa at an unusual site.  J Hematopathol 16, 123–124 (2023).

Kallen ME, Saito Y, Hardy NM, Ning Y, Singleton T, Singh ZN, Koka R. Attack of the clones: a T-cell population resembling adult T-cell leukemia/lymphoma, and large granular lymphocytosis, in an HTLV-2-infected patient. J Hematopathol 15, 255–258 (2022).

Kallen ME, Koka R, Singh ZN, Ning Y, Kocoglu MH, Badros AZ, Niyongere S, Duong VH, Emadi A, Baer MR. Therapy-related B-lymphoblastic leukemia after multiple myeloma. Leuk Res Rep. 2022 Nov 1;18:100358. doi: 10.1016/j.lrr.2022.100358. PMID: 36353199; PMCID: PMC9637917.

Alkhaldi H, Sewell D, Ning Y, Kallen ME, Emadi A, Hardy NM, Baer MR.  Durable response to ivosidenib in post-transplant relapse and leukemic transformation of myelodysplastic syndrome with new complex karyotype and IDH1 R132C mutation. Leuk Lymphoma. 2022 Dec;63(12):3000-3003. doi: 10.1080/10428194.2022.2105329. Epub 2022 Aug 8. PMID: 35938721; PMCID: PMC9779946.

Kline KAF, Law J, Lee ST, Kallen M.  Waldenström Macroglobulinemia and simultaneous intravascular large B-cell lymphoma: rare transformation or unhappy coincidence?  Clin Lymphoma Myeloma Leuk. 2022 Aug;22(8):e788-e791.

Kallen ME, Khalil A, DeRosa PA, Baer MR.  Disseminated histoplasmosis mimicking hematologic malignancy in a patient with HIV.  eJHaem.2022;1–2.

Markidan J, Hardy N, Kallen M, Ma L.  Epithelioid hemangioma involving large arteries in the skin.  J Cutan Pathol 2022 Apr;49(4):377-380.

Jeyaraju M, Macatangay RA, Munchel AT, York TA, Montgomery EA, Kallen ME.  Embryonal rhabdomyosarcoma with posttherapy cytodifferentiation and aggressive clinical course.  Case Rep Pathol. 2021 Nov 8;2021:1800854.

Kallen ME, Hornick JL.  From the ashes of "Ewing-like" sarcoma: A contemporary update of the classification, immunohistochemistry, and molecular genetics of round cell sarcomas.  Semin Diagn Pathol. 2021 Oct 29:S0740-2570(21)00076-9.

Kline KAF, Kallen ME, Duong VH, Law JY.  Acute lymphoblastic leukemia and acute lymphoblastic lymphoma: same disease spectrum but two distinct diagnoses.  Curr Hematol Malig Rep. 2021 Oct;16(5):384-393.

Song L, Stashek KM, Benyounes A, Davis DL, Mulligan ME, Ng VY, Kallen ME.  Epithelioid sarcoma with retained INI1 (SMARCB1) expression.  Histopathology. 2021 Feb;78(3):464-466.

Kallen ME, Hornick JL.  The new 2020 WHO classification: what’s new in soft tissue tumor pathology?  Am J Surg Pathol. 2021 Jan;45(1):e1-e23.

Amin JD, Kallen ME, Hatten KM.  Radical tonsillectomy and superior pharyngeal constrictor anatomy: a cadaveric and oncologic specimen assessment.  ORL J Otorhinolaryngol Relat Spec. 2020 Jul 13:1-9.

Kallen ME, Koka R, Singh Z, Sanchez-Petitto G, Zaman QU, Yared JA, Duong VH.  Teenage mutant neutrophilic precursors: Leukemia cutis with IDH2 mutation on enasidenib therapy. Leuk Res. 2020 Jun 25;96:106406.

Mininni J, Singh Z, Strauch E, Macatangay RA, Kallen ME.  Warthin–Finkeldey-like cells in a lymph node from a child with Li-Fraumeni syndrome.  J Hematopathol. 2019 Dec; 12(4):215-6.

Kallen ME, Dulau-Florea AE, Maric I, Calvo KR.  Acquired and germline predisposition to bone marrow failure: Diagnostic features and clinical implications.  Semin Hematol. 2019 Jan;56(1):69-82.

Kallen ME, Alexanian S, Said J, Quintero-Rivera F.  Triple hit lymphoma: rare cases with less dire than usual prognosis.  Int J Surg Pathol. 2016 Dec;24(8):709-714.

Kallen ME, Naini BV.  Intraductal oncocytic papillary neoplasms of the pancreas.  Arch Pathol Lab Med. 2016 Sep;140(9):992-6.

Shin DS, Sherry T, Kallen ME, Wong S, Drakaki A.  Human epidermal growth factor receptor 2 (HER-2/neu)-directed therapy for rare metastatic epithelial tumors with HER-2 amplification. Case Rep Oncol. 2016 Jun 11;9(2):298-304.

Fonseka LN, Kallen ME, Serrato-Guillen A, Chow R, Tirado CA.  Cytogenetics and molecular genetics of prostate cancer: a comprehensive update.  J Assoc Genet Technol. 2015;41(3):100-11.

Kallen ME, Sim MS, Radosavcev BL, Humphries RM, Ward DC, Apple SK.  A quality initiative of post-operative radiographic imaging performed on mastectomy specimens to reduce histology cost and pathology report turn-around time.  Ann Diagn Pathol. 2015 Oct;19(5):353-8.

Kallen ME, DeNicola MM, Said J.  Coexpression of cytokeratin and B-cell markers – a rare finding with new implications.  J Hematopathol.  2015 Jun; 8(2):95-97.

Kallen ME, Kulkarni SK, Rao NP, Pullarkat ST, Said J, Tirado CA, Ahmed R, Miller JM, Chung PY, Kahn DG, Song SX.  B-lymphoblastic transformation of mantle cell lymphoma/leukemia with “double hit” changes.  J Hematopathol. 2015 Mar; 8(1):31-36.

Tirado CA, Shabsovich D, Yeh L, Pullarkat ST, Yang L, Kallen M, Rao N.  A (1;19) translocation involving TCF3-PBX1 fusion within the context of a hyperdiploid karyotype in adult B-ALL: a case report and review of the literature.  Biomark Res. 2015 Feb 18;3:4.

Kallen ME, Kim Y, Yang L, Rao NP, Tirado CA.  A cryptic t(11;14) translocation in mantle cell lymphoma highlights the importance of FISH.  J Assoc Genet Technol. 2015;41(1):13-6.

Kallen ME, Boon-Unge K, Yong WH, Pope WB, Frazee JG, Vinters HV.  Isolated choroid plexus granulomas: initial presentation of neurosarcoidosis?  Can J Neurol Sci. 2014 Jan;41(1):112-4.

Kallen ME, Sanders ME, Gonzalez AL, Black JO, Keedy VL, Hande KR, Homlar KC, Halpern JL, Holt GE, Schwartz HS, Coffin CM, Cates JM.  Nuclear p63 expression in osteoblastic tumors.  Tumour Biol. 2012 Oct; 33(5): 1639-44.

Kallen ME, Nunes Rosado FG, Gonzalez AL, Sanders ME, Cates JM.  Occasional staining for p63 in malignant vascular tumors: a potential diagnostic pitfall.  Pathol Oncol Res. 2012 Jan; 18(1): 97-100.

McElroy SJ, Hobbs S, Kallen M, Tejera N, Rosen MJ, Grishin A, Matta P, Schneider C, Upperman J, Ford H, Polk DB, Weitkamp JH.  Transactivation of EGFR by LPS induces COX-2 expression in enterocytes.  PLoS One. 2012; 7(5): e38373.


Clinical Specialty Details

  • Hematopathology
  • Bone and soft tissue pathology
  • Surgical pathology