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Reney Anthony Henderson, MD

Academic Title:

Associate Professor

Primary Appointment:




Phone (Primary):

(410) 328-3961

Phone (Secondary):

(410) 328-9813


(410) 328-5531

Education and Training


2005-2009: B.S., Biology, summa cum laude, Howard University, Baltimore, MD

2011-2012: M.D., University of Maryland School of Medicine, Baltimore, MD

Post Graduate Education and Training

2013-2017: Residency, Anesthesiology (Categorical with preliminary year in Internal Medicine), University of Maryland Medical Center, Baltimore, MD

2017-Present: Fellowship, Cardiothoracic Anesthesiology, University of Maryland Medical Center, Baltimore, MD


Dr. Henderson is a native of the Maryland/DC suburbs, he graduated from Howard University and completed medical school training at the University of Maryland School of Medicine. He completed his residency in anesthesiology at University of Maryland Medical Center, where he served as the Chief Resident in 2016-2017. He stayed on with the Department and completed his fellowship in Cardiothoracic Anesthesiology in 2017-2018.  He will be joining the Cardiac Division, working primarily at UMMC.

Highlighted Publications

  1. Hecker PA, Galvao TF, O'Shea KM, Brown BH, Henderson R, Riggle H, Gupte SA, Stanley WC. High-sugar intake does not exacerbate metabolic abnormalities or cardiac dysfunction in genetic cardiomyopathy. Nutrition. 2012;28(5):520-6. PMID: 22304857.
  2. Henderson R, Chow R, Morales R, Taylor B, Mazzeffi MA. Removal of an Entrapped Lumbar Drain After Thoracic Endovascular Aortic Repair. A A Case Rep. 2016;7(4):93-5. PMID: 27525494.
  3. Henderson RS, Deshpande S, Williams B, Taylor BS, Tanaka KA. Idarucizumab for Dabigatran Reversal in Emergency Type-A Aortic Dissection. J Cardiothor Vasc Anesth. 2017;31(6):e80-e81. PMID: 27498256.
  4. Henderson R, Chow JH, Tanaka KA. A Bridge to Bloodless Surgery: Use of Hemoglobin-Based Oxygen Carrier for Anemia Treatment and Autologous Blood Preservation During Redo Pulmonic Valve Replacement. J Cardiothorac Vasc Anesth. 2018;33(7):1973-1976. PMID: 30529178.
  5. Hasan S, Abuelkasem E, Williams B, Henderson R, Mazzeffi MA, Tanaka KA. Factor IX from prothrombin complex concentrate augments low-dose tissue factor-triggered thrombin generation in vitro. Br J Anaesth. 2018;121(4):936-943. PMID: 30236256.
  6. Henderson RA, Mazzeffi MA, Tanaka KA. Fibrinogen Concentrate: Is It Standard Currency or Bitcoin in Bleeding Management? Anesth Analg. 2018;127(3):603-604. PMID: 30113977.
  7. Chow JH, Galvagno SM, Tanaka KA, Mazzeffi MA, Chancer Z, Henderson R, McCurdy MT. When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report. A A Pract. 2018;11(7):175-180. PMID: 29688923.
  8. Abuelkasem E, Mazzeffi MA, Henderson RA, Wipfli C, Monroe A, Strauss ER, Chow JH, Tanaka KA. Clinical impact of protamine titration-based heparin neutralization in patients undergoing coronary bypass grafting surgery. J Cardiothorac Vasc Anesth. 2019;33(8):2153-2160. PMID: 30737123.
  9. Tanaka KA, Bharadwaj S, Hasan S, Judd M, Abuelkasem E, Henderson RA, Chow JH, Williams B, Mazzeffi MA, Crimmins SD, Malinow AM. Elevated fibrinogen, von Willebrand factor, and Factor VIII confer resistance to dilutional coagulopathy and activated protein C in normal pregnant women. Br J Anaesth. 2019;122(6):751-759. PMID: 30916034.
  10. Tanaka KA, Henderson R, Williams B. Heparin-Induced Thrombocytopenia and Cardiac Surgery: Can We Do It All With Cangrelor? A A Pract. 2019;13(9):366. PMID: 31567127.
  11. Henderson RA, Mazzeffi MA, Strauss ER, Williams B, Wipfli C, Dawood M, Taylor BS, Tanaka KA. Impact of intraoperative high-volume autologous blood collection on allogeneic transfusion during and after cardiac surgery: a propensity score-matched analysis. Transfusion. 2019;59(6):2023-2029. PMID: 30882929.
  12. Anders M, Rock P, Cartron A, Chow J, Henderson R, Martz D, Tanaka K, Mazzeffi M. Isolated Platelet Concentrate Transfusion During Surgery: A Single-Center Observational Cohort Study. Transfusion. 2019;59(5):1661-1666. PMID: 30693940.
  13. Tanaka KA, Henderson RA, Strauss ER. Evolution of Viscoelastic Coagulation Testing. Expert Rev Hematol. 2020;13(7):697-707. PMID: 32310702.
  14. Williams B, Henderson R, Reformato VS, Pham T, Taylor BS, Tanaka KA. Hemostasis Management of Patients Undergoing Emergency Cardiac Surgery After Ticagrelor Loading. J Cardiothorac Vasc Anesth. 2020;34(1):168-174. PMID: 31375405.
  15. Henderson RA, Choi S. History and Practice of Acute Normovolemic Hemodilution. Curr Anesthesiol Rep. 2020;10, 282-288.
  16. Chow JH, Abuelkasem E, Sankova S, Henderson RA, Mazzeffi MA, Tanaka KA. Reversal of Vasodilatory Shock: Current Perspectives on Conventional, Rescue, and Emerging Vasoactive Agents for the Treatment of Shock. Anesth Analg. 2020;130(1):15-30. PMID: 31348056.
  17. Madathil R, Tabatabai A, Rabin J, Menne A, Henderson R, Mazzeffi M, Scalea T, Tanaka K. Thromboelastometry and D-dimer elevation in Coronavirus-2019. J Cardiothorac Vasc Anesth. 2020;34(12):3495-3496. PMID: 32593588.
  18. Henderson RA, Judd M, Strauss ER, Gammie JS, Mazzeffi MA, Taylor BS, Tanaka KA. Hematologic evaluation of intraoperative autologous blood collection and allogeneic transfusion in cardiac surgery. Transfusion. 2021;61(3):788-798. PMID: 33423288.
  19. Pasrija C, Quinn RW, Bernstein D, Tran D, Alkhatib H, Rice M, Morales D, Shah A, Ghoreishi M, Strauss ER, Henderson R, D'Ambra MN, Gammie JS. Mitral Valve Translocation: A Novel Operation for the Treatment of Secondary Mitral Regurgitation. Ann Thorac Surg. 2021;112(6):1954-1961. PMID: 34419436.
  20. Patel PA, Henderson RA, Bolliger D, Erdoes G, Mazzeffi MA. The Year in Coagulation: Selected Highlights from 2020. J Cardiothorac Vasc Anesth. 2021:35(8):2260-2272. PMID: 33781668.
  21. Mazzeffi M, Judd M, Rabin J, Tabatabai A, Menaker J, Menne A, Chow J, Shah A, Henderson R, Herr D, Tanaka K. Tissue Factor Pathway Inhibitor Levels During Veno-Arterial Extracorporeal Membrane Oxygenation in Adults. ASAIO J. 2021;67(8):878-883.  PMID: 33606392.
  22. Strauss ER, Li S, Henderson R, Carpenter R, Guo D, Thangaraju K, Katneni U, Buehler PW, Gobburu JV, Tanaka KA. A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 2022;36(8 Pt A):2473-2482. PMID: 35094925.
  23. Fabbro M, Patel PA, Henderson RA, Bolliger D, Tanaka KA, Mazzeffi MA. Coagulation and Transfusion Updates From 2021. J Cardiothorac Vasc Anesth. 2022;36(9):3447-3458. PMID: 35750604.
  24. Mazzeffi M, Henderson R, Krause E, Rabin J, Madathil R, Chow J, Grazioli A, Meyer M, Wu Z, Tanaka K. In Vitro Comparison of Recombinant and Plasma-Derived von Willebrand Factor Concentrate for Treatment of Acquired von Willebrand Syndrome in Adult Extracorporeal Membrane Oxygenation Patients. Anesth Analg. 2022;134(2):312-321. PMID: 34903705.
  25. Tanaka KA, Henderson R, Thangaraju K, Morita Y, Mazzeffi MA, Strauss E, Katneni U, Buehler PW. In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients. Haemophilia. 2022;28(1):183-190. PMID: 34735039.
  26. Strauss ER, Quinn RW, Pasrija C, Henderson R, Holmes SD, D'Ambra MN, Gammie JS. Intraoperative echocardiographic assessment of mitral valve translocation. Eur J Cardiothorac Surg. 2022;62(2):ezac133. PMID: 35277715.
  27. Denault A, Couture EJ, De Medicis E, Shim J, Mazzeffi M, Henderson RA, Langevin S, Dhawan R, Michaud M, Guensch DP, Berger D, Erb JM, Gebhard CE, Royse X, Levy D, Lamarche Y, Dagenais F, Deschamps A, Desjardins G, Beaubien-Souligny W. Perioperative Doppler ultrasound assessment of portal vein flow pulsatility in high-risk cardiac surgery patients: a multicentre prospective cohort study. Br J Anaesth. 2022;129(5):659-669. PMID: 36184294.
  28. Fontaine MJ, Lasola JJ, Henderson RA. Perioperative Platelet Transfusion: Not All Platelet Products Are Created Equal. Curr Anesthesiol Rep. 2022;12(1): DOI: 10.1007/s40140-022-00522-4.
  29. Choi S, Mazzeffi MA, Henderson R, Mondal S, Morita Y, Deshpande S, Tanaka K. The FIBTEM paradox: Do coronary artery bypass grafting patients with high baseline FIBTEM clot firmness need more allogeneic blood transfusion? Transfusion. 2022;62(10):2020-2028. PMID: 36053950.
  30. Mazzeffi M, Henderson R, Powell E, Strauss E, Williams B, Tanaka K, Yang S, Deatrick K, Madathil R. Thrombopoietin, Soluble CD40 Ligand, and Platelet Count During Veno-arterial Extracorporeal Membrane Oxygenation. ASAIO J. 2022;68(5):e77-e79. PMID: 34081052.
  31. Guinn N, Tanaka K, Erdoes G, Kwak J, Henderson R, Mazzeffi M, Fabbro M, Raphael J. The Year in Coagulation and Transfusion: Selected Highlights from 2022. J Cardiothor Vasc Anesth. 2023;



Additional Publication Citations

Henderson RA. Vascular Anesthesia Procedures. Alan Kaye, eds. Hemostasis, Thrombosis, Transfusion, and Blood Conservation. Oxford University Press: 2021; pp 23-40. 


Research Interests

Research Interest:

  • Blood product utilization
  • Coagulation profiles of cardiac surgery patients
  • Effect of blood products on endothelial function
  • Alternative blood product utilization
  • Left ventricular and right ventricular strain assessment
  • Cardiac surgery-induced acute kidney injury

 Research Activities:

  • Blood Conservation Techniques in Cardiac Surgery
  • Benefits of Autologous Blood in Cardiac Surgical Patients
  • Novel Platelet Substitutions and Advancements
  • Novel Hemodynamic Monitors in Cardiac Surgery
  • Hemolysis on Cardiopulmonary Bypass
  • Viscoelastic Coagulation Monitors and Point of Care Assessment of Coagulopathy in Cardiac Surgical Patients
  • Hemoglobin Oxygen Based Carrier Benefits and Pitfalls

Clinical Specialty Details

  • Cardiothoracic Anesthesiology
  • Transesophageal Echocardiography

Awards and Affiliations

2009 Scholarship, UMSOM
2016 Chief Resident, UMMC, Department of Anesthesiology

Grants and Contracts


PI,2%; PI – Reney Henderson

Optimized administration of Prothrombin complex concentrate (PCC)

vs Standard

Transfusion during/after Heart Transplantation (OPSTAHT)

CSL Behring

Award Total: $309,685.80


PI,2%; PI - Reney Henderson  

Reduction of Free Hemoglobin during Cardiac Surgery (REFRESH II)


Award Total: $110,661.13


PI,2%; PI - Reney Henderson

ROTEM sigma External Matrix Comparison Study: Venous versus Arterial Citrated Whole Blood Samples

Award Total: $30,754.10


PI,2%; PI - Reney Henderson

ROTEM Sigma External Method Comparison

Instrumentation Laboratory Company

Award Total: $42,628.30


PI,2%; PI - Reney Henderson

ECOM vs TDCO and FLOTRAC Clinical Accuracy Study

Award Total: $69,915.40


PI, 1%

CRYPTICS- Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery

United States Military

Award Total: $384,284.00

Completed Grants


SCA Fellow Travel Grant

Society of Cardiovascular Anesthesiologists

Award Total: $1,000.00


PI,2%; PI - Reney Henderson

Emicizumab: A Pilot in Vitro Experiment

Award Total: $60,546.34


Community Service

2005-2007 Participant, DC Helping the Homeless Walk
2008-2009 Physician's Aid, Howard University Hospital

Translator, Catholic Charities, Washington, DC    English to Spanish Translator at Free Healthcare Clinic

2009-2012 Healthcare for the Homeless, University of Maryland, Baltimore, Free Healthcare Clinic
2021-present Participant, Susan G. Komen 5K Walk
2022-present Participant, March of Dimes Walk

Professional Activity

Institution - Departmental


Member, Clinical Competency Committee, Anesthesiology, University of Maryland School of Medicine



Resident Cardiothoracic Anesthesia Rotation Director, University of Maryland School of Medicine



Director, Anesthesiology Resident Transesophageal Echocardiography Rotation, Department of Anesthesiology, University of Maryland School of Medicine


Member, IDEA (Inclusion, Diversity, Equity and Antiracism) Taskforce, Department of Anesthesiology, University of Maryland School of Medicine


Associate Program Director, Department of Anesthesiology, University of Maryland School of Medicine, Cardiothoracic Anesthesiology Fellowship Program

Institutional - UMSOM
2020-present Member, Admissions Committee, UMSOM
2020-present Member, Diversity Advisory Committee, UMSOM
2022-present Member, LCME Subcommittee, UMSOM
Institutional - UMB
2020-present  Member, Faculty Senate, University of Maryland Baltimore
National Service


Member, Blood Conservation Working Group, Society of Cardiovascular Anesthesiologists


Member, Blood Conservation Committee, American Society of Anesthesiologists


Member, American Society of Anesthesiologists, Cardiovascular and Thoracic Education Committee


Member, American Society of Anesthesiologists, Cardiovascular and Thoracic Committee
2023-present Member, Acute Kidney Injury Working Group Sub-committee, Society of Cardiovascular Anesthesiologists
2023-present  Editor, Frontier Anesthesiology Journal