Skip to main content

Michelle G. Giglio, PhD

Academic Title:

Associate Professor

Primary Appointment:


Administrative Title:

Associate Director for Education & Outreach for the Institute of Genome Sciences

Additional Title:

Academic and Outreach Coordinator, Institute for Genome Sciences; Associate Director for Analysis, Informatics Resource Center, Institute for Genome Sciences


Health Sciences Facility III, 670 West Baltimore St, Baltimore 21201

Phone (Primary):

(410) 706-7694

Education and Training

B.S. University of Maryland College Park, 1990

Ph.D. Johns Hopkings University School of Medicine, 1997

Postdoc The Insititue for Genomic Research, Rockville, MD 1997-1998


Staff Scientist, The Institute for Genomic Research, 1998-2007

Assistant Professor, University of Maryland School of Medicine, Department of Medicine and Institute for Genome Sciences, 2007-2015

Associate Professor, University of Maryland School of Medicine, Department of Medicine and Institute for Genome Sciences, 2015-Present

Research/Clinical Keywords

genomics, transcriptomics, metagenomics, microbiome, annotation, ontology, training, outreach, K-12 outreach

Highlighted Publications


Carey GB, Ezelle HJ, Steinle N, Cao Q, Simington L, Matson C, Singh N, Jones L, Mohindra P, Cullen KJ, Giglio M, Parker E, Hassel BA. Robust Institutional Support and Collaboration Between Summer Training Programs in Cancer and Biomedicine Drive the Pivot to a Virtual Format in Response to the COVID Pandemic. J Cancer Educ. 2022 Jan 31:1–15.


Nadendla S, Jackson R, Munro J, Quaglia F, Mészáros B, Olley D, Hobbs ET, Goralski SM, Chibucos M, Mungall CJ, Tosatto SCE, Erill I, Giglio MG. ECO: the Evidence and Conclusion Ontology, an update for 2022. Nucleic Acids Res. 2022 Jan 7;50(D1):D1515-D1521.

BRAIN Initiative Cell Census Network (BICCN). A multimodal cell census and atlas of the mammalian primary motor cortex. Nature. 2021 Oct;598(7879):86-102.


Yao Z, Liu H, Xie F, Fischer S, Adkins RS, Aldridge AI, Ament SA, Bartlett A, Behrens MM, Van den Berge K, Bertagnolli D, de Bézieux HR, Biancalani T, Booeshaghi AS, Bravo HC, Casper T, Colantuoni C, Crabtree J, Creasy H, Crichton K, Crow M, Dee N, Dougherty EL, Doyle WI, Dudoit S, Fang R, Felix V, Fong O, Giglio M, Goldy J, Hawrylycz M, Herb BR, Hertzano R, Hou X, Hu Q, Kancherla J, Kroll M, Lathia K, Li YE, Lucero JD, Luo C, Mahurkar A, McMillen D, Nadaf NM, Nery JR, Nguyen TN, Niu SY, Ntranos V, Orvis J, Osteen JK, Pham T, Pinto-Duarte A, Poirion O, Preissl S, Purdom E, Rimorin C, Risso D, Rivkin AC, Smith K, Street K, Sulc J, Svensson V, Tieu M, Torkelson A, Tung H, Vaishnav ED, Vanderburg CR, van Velthoven C, Wang X, White OR, Huang ZJ, Kharchenko PV, Pachter L, Ngai J, Regev A, Tasic B, Welch JD, Gillis J, Macosko EZ, Ren B, Ecker JR, Zeng H, Mukamel EA. A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex. Nature. 2021 Oct;598(7879):103-110.


Vita R, Zheng J, Jackson R, Dooley D, Overton JA, Miller MA, Berrios DC, Scheuermann RH, He Y, McGinty HK, Brochhausen M, Lin AY, Jain SB, Chibucos MC, Judkins J, Giglio MG, Feng IY, Burns G, Brush MH, Peters B, Stoeckert CJ Jr. Standardization of assay representation in the Ontology for Biomedical Investigations. Database (Oxford). 2021 Jul 9;2021:baab040

Hobbs ET, Goralski SM, Mitchell A, Simpson A, Leka D, Kotey E, Sekira M, Munro JB, Nadendla S, Jackson R, Gonzalez-Aguirre A, Krallinger M, Giglio M, Erill I. ECO-CollecTF: A Corpus of Annotated Evidence-Based Assertions in Biomedical Manuscripts. Front Res Metr Anal. 2021 Jul 13;6:674205.

Creasy HH, Felix V, Aluvathingal J, Crabtree J, Ifeonu O, Matsumura J, McCracken C, Nickel L, Orvis J, Schor M, Giglio M, Mahurkar A, White O. HMPDACC: a Human Microbiome Project Multi-omic data resource. Nucleic Acids Res. 2021 Jan 8;49(D1):D734-D742. PMID: 33305317.

Gene Ontology Consortium. The Gene Ontology resource: enriching a GOld mine. Nucleic Acids Res. 2021 Jan 8;49(D1):D325-D334. PMID: 33290552.

Deborah A. Siegele, Sandra A. LaBonte, Peter I-Fan Wu, Marcus C. Chibucos, Suvarna Nandendla, Michelle G. Giglio & James C. Hu. Phenotype annotation with the ontology of microbial phenotypes (OMP). Journal of Biomedical Semantics, volume 10, Article number: 13 (2019)

Lloyd-Price J, Mahurkar A, Rahnavard G, Crabtree J, Orvis J, Hall AB, Brady A,Creasy HH, McCracken C, Giglio MG, McDonald D, Franzosa EA, Knight R, White O,Huttenhower C. Strains, functions and dynamics in the expanded Human Microbiome Project. Nature. 2017 Oct 5;550(7674):61-66.

Research Interests

Data Coordination and Standardization: I have been/am a co-investigator on several data coordination center projects including the Human Microbiome Project Data Coordination Center, the Neuroscience Multi-Omic (NeMO) Archive, and the Common Fund Data Ecosystem Coordinating Center. For these projects I have worked to enhance the FAIRness of data through the appliation of community standards for data analysis and metadata capture.

Ontology Development: I am the PI of the Evidence Ontology. I am a co-investigator on the Ontology for Microbial Phenotypes. I have been part of the Gene Ontology Consortium for nearly 20 yars working in areas of term developoment related to prokaryotic biology. The use of ontologies and controlled vocabularies for the capture of information vastly increases its reusability and interoperability.

Outreach: I organize and run several STEM events to K-12 schools/programs each year. These are focused primarily at middle and high school students with a particular focus on the west Baltimore community.

Training: I run a professional development workshop program that includes multiple different workshops focused on aspects of bioinformatics including genomics, transcriptomics, metagenomics, comparative genomics, and programming.


Awards and Affiliations

I was named one of Maryland's Top 100 Women by the Daily Record in 2014

I received the Founders Week Public Servant of the Year award, UMB 2019

Community Service

I am involved in multiple outreach events to local K-12 students including the CURE Scholars program and the Maryland Microbiome Project.