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Baoshe Zhang, PhD

Academic Title:

Assistant Professor

Primary Appointment:

Radiation Oncology

Location:

UMMC/Gudelsky, GGJ-20B

Phone (Primary):

410-328-0787

Fax:

410-328-2618

Education and Training

Dr. Baoshe Zhang received his Ph.D. in Physics at the Hong Kong University of Science and Technology in 2003. Dr. Zhang is currently an Assistant Professor in the Department of Radiation Oncology at the University of Maryland School of Medicine. Following his graduate training, he joined the University of Lethbridge in Canada as Research Associate. While there, he developed a second-generation sub-millimeter Fourier transform spectrometer for the James Clerk Maxwell Telescope in Hawaii and worked on the spectral and photometric imaging receiver project for the Herschel Space Observatory of European Space Agency. He then moved to the Department of Radiation Oncology at Virginia Commonwealth University as a faculty member where he was working on Image-Guided Adaptive Radiation Therapy.

Research/Clinical Keywords

Image-Guided Adaptive Radiation Therapy and Informatics in Radiation Therapy

Highlighted Publications

  1. B. Zhang, S. Chen, W. D'Souza, E. Nichols, B. Yi. A practical contingency plan for radiation oncology. J Appl Clin Med Phys, April (2020) (DOI: 10.1002/acm2.12886)
  2. B. Zhang, S. Chen, W. D'Souza, B. Yi. A systematic quality assurance framework for the upgrade of radiation oncology information systems. Physica Medica 69, 28(2020)
  3. Zhang B, Lee S, Chen S, Zhou J, Prado K, D’Souza W, Yi B. Action levels on dose and anatomic variation (ALDAV) for daily off-line plan evaluation: Preliminary results. Practical Radiation Oncology 9, 49(2019)
  4. J. Zhou, Z. Yan, G. Lasio, J. Huang, B. Zhang, N. Sharma, K. Prado, W. D’Souza. Automated compromised right lung segmentation method using a robust atlas-based active volume model with sparse shape composition prior in CT. Computerized Medical Imaging and Graphics 46, 47 (2015)
  5. M. Fatyga, N. Dogan, J. Williamson, E. Weiss, W. Sleeman, W. Lehman, B.Zhang, K.Wijesooriya, G. Christensen. A comparison of three Deformable Image Registration Algorithms in 4DCT using conventional contour based methods and voxel-by-voxel comparison methods. Front Oncol 5, 17(2015)
  6. B.Zhang, F.K.Lee, O.K.C.Tsui, P.Sheng. Liquid Crystal Orientation Transition on Microtextured Substrates. Phys. Rev. Lett. 91, 215501 (2003).

Additional Publication Citations

Peer-reviewed journal articles

  

  1. Wang, B.Zhang, F.Li. Dynamic behavior of soliton in optical fibre with arbitrary perturbation of the dielectric constant. Chinese. J. of Lasers A25, 453(1998).
  2. Ma, B. Zhang, W.Y.Tam, P.Sheng. Dielectric-constant evaluation from microstructures. Phys.Rev.B 61, 962(2000).
  3. Zhang, P.Sheng, H.S.Kwok. Optical measurement of azimuthal anchoring strength in nematic liquid crystals. Phys.Rev.E 67, 041713(2003).
  4. Zhang, F.K.Lee, O.K.C.Tsui, P.Sheng. Liquid Crystal Orientation Transition on Microtextured Substrates. Phys. Rev. Lett. 91, 215501 (2003).
  5. K.C.Tsui, F.K.Lee, B.Zhang, and P.Sheng. First-order liquid crystal orientation transition on inhomogeneous substrates. Phys.Rev.E 69, 021704 (2004).
  6. K.Lee, B.Zhang, P.Sheng, H.Sing.Kwok, and O.K.C.Tsui. Continuous Liquid Crystal Pretilt Control through Textured Substrates. Appl. Phys. Lett. 85, 5556(2004).
  7. Fatyga, B.Zhang, W.C.Sleeman. Designing and Implementing a Computing Framework for Image-Guided Radiation Therapy Research. IEEE Computing in Science and Engineering 14(4), 57 (2012).
  8. Fatyga, N. Dogan, J. Williamson, E. Weiss, W. Sleeman, W. Lehman, B.Zhang, K.Wijesooriya, G. Christensen. A comparison of three Deformable Image Registration Algorithms in 4DCT using conventional contour based methods and voxel-by-voxel comparison methods. Front Oncol 5, 17(2015)
  9. Zhou, Z. Yan, G. Lasio, J. Huang, B. Zhang, N. Sharma, K. Prado, W. D’Souza. Automated compromised right lung segmentation method using a robust atlas-based active volume model with sparse shape composition prior in CT. Computerized Medical Imaging and Graphics 46, 47 (2015)
  10. Zhang B, Lee S, Chen S, Zhou J, Prado K, D’Souza W, Yi B. Action levels on dose and anatomic variation (ALDAV) for daily off-line plan evaluation: Preliminary results. Practical Radiation Oncology 9, 49(2019)
  11. Zhang, S. Chen, W. D'Souza, B. Yi. A systematic quality assurance framework for the upgrade of radiation oncology information systems. Physica Medica 69, 28(2020)
  12. Zhang, S. Chen, W. D'Souza, E. Nichols, B. Yi. A practical contingency plan for radiation oncology. J Appl Clin Med Phys, April (2020) (DOI: 10.1002/acm2.12886)

 

Abstracts and Proceedings

  

  1. B.Zhang, P.Sheng. Surface Switching Behavior of Liquid Crystal Induced by Micro Comb-like Electrodes. American Physical Society March Meeting, Seattle (2001).
  2. B.Zhang, F.K.Lee, P.Sheng, O.K.C.Tsui. Liquid crystal orientation transition induced by microtextured substrates. American Physical Society March Meeting, Austin (2003).
  3. O.K.C.Tsui, F.K.Lee, B.Zhang, P.Sheng. Novel Liquid Crystal Orientation Transition on Inhomogeneous Substrates. American Physical Society March Meeting, Montreal (2004).
  4. D.A.Naylor, B.G.Gom, and B.Zhang. Preliminary design of FTS-2: an imaging Fourier transform spectrometer for SCUBA-2. Proc. SPIE 6275 (Millimeter and Submillimeter Detectors and Instrumentation for Astronomy), 62751Z (2006).
  5. L.D.Spencer, D.A.Naylor, B.Zhang, P.Davis-Imhof, T.R.Fulton, J.Baluteau, M.J.Ferlet, T.L.Lim, E.T.Polehampton, B.M.Swinyard. Performance Evaluation of the Herschel/SPIRE Instrument Flight Model Imaging Fourier Transform Spectrometer.  Proc. SPIE, Space Telescopes and Instrumentation: Optical, Infrared, and Millimeter, 7010(2008).
  6. B.G.Gom, D.A.Naylor, B.Zhang. Integration and testing of FTS-2: an imaging Fourier transform spectrometer for SCUBA-2. Proc. SPIE, Millimeter and Submillimeter Detectors and Instrumentation for Astronomy IV, 7020(2008).
  7. L.D.Spencer, D.A.Naylor, B.Zhang, P.Davis-Imhof, T.R.Fulton, J.Baluteau, M.J.Ferlet, T.L.Lim, E.T.Polehampton, B.M.Swinyard. The Herschel/SPIRE Instrument Flight Model Imaging Fourier Transform Spectrometer Performance Evaluation. Canadian Astronomical Society, May 2008.
  8. N. Dogan, W. Sleeman, M.Fatyga, W.Lehman, G.Christenson, J.Wu, E.Weiss, B.Zhang, J.Williamson. Verification of a Deformable Image Registration Algorithm for Head and Neck Cancer Therapy. Med. Phys. 37, 3155(2010).
  9. B.Zhang, W.C.Sleeman, M. Fatyga, N. Dogan. An Integrated Software Environment for Image Guided Adaptive Radiation Therapy Research. Med. Phys. 37, 3245(2010).
  10. M. Fatyga, K.Wijesooriya, N. Dogan,W.C.Sleeman, B.Zhang, G.E.Christensen. Volume Based Comparison of DIR Algorithms using Spatial Discrepancy Volume Histograms. Med. Phys. 38, 3551(2011).
  11. B.Zhang, W.C.Sleeman, M. Fatyga, N. Dogan. An Integrated IGART Planning Environment. Med. Phys. 38, 3492(2011).
  12. B.Zhang. A Free and Open Source DICOM Solution: DicomPack. Med. Phys. 39, 3753(2012).
  13. B.Zhang. A Patient Data Management System for Philips Pinnacle-3 Treatment Planning System. Med. Phys. 39, 3753(2013).
  14. J.Zhou, Z.Yan, S.Zhang, B.Zhang, G.Lasio, K.Prado, W.D’Souza.Automated Lung Segmentation Method Using Atlas-Based Sparse Shape Composition With a Shape Constrained Deformable Mode. Annual Meeting of AAPM, Austin (2014).
  15. B. Zhang, S. Chen, Y. Mutaf, K.Prado, W.D’Souza. Smart Auto-Planning Framework in an EMR Environment (SAFEE). Annual Meeting of AAPM, Austin (2014).
  16. J. Zhou, G. Lasio, B. Yi, J Huang, S. Chen, B. Zhang, K Langen, K Prado, W D'Souza. The CBCT Dose Calculation Using a Patient Specific CBCT Number to Mass Density Conversion Curve Based On a Novel Image Registration and Organ Mapping Method in Head-And-Neck Radiation Therapy. Annual Meeting of AAPM, Anaheim(2015).
  17. K. Langen, M. Guerrero, M. Killefer, H. Xu, J. Zhou, B. Zhang, S Chen. Commissioning of a Commercial 3D Dose Calculation Program. Annual Meeting of AAPM, Anaheim(2015).
  18. W. D'Souza, B. Zhang, S. Feigenberg, G. D'Souza, K. Prado, W. Regine. Compliance With Evidence-Based Treatment Planning DVH Guidelines In An Academic Multi-Site Radiation Oncology Practice Setting. Annual Meeting of AAPM, Anaheim(2015).
  19. S. Chen, H. Zhang, B. Zhang, W. D'Souza. A Logistic Function-Based Model to Predict Organ-At-Risk (OAR) DVH in IMRT Treatment Planning. Annual Meeting of AAPM, Anaheim(2015).
  20. S. Chen, H. Zhang, B. Zhang, W. D'Souza. Differences in Treatment Plan Quality and Delivery Between Two Commercial Treatment Planning Systems for Volumetric Arc-Based Radiation Therapy. Annual Meeting of AAPM, Anaheim(2015).
  21. Y. Liu, T. Diwanji, B. Zhang, J. Zhuo, R. Gullapalli, R. Morales, W. D'Souza. DCE-MRI Before and During Treatment for Prediction of Concurrent Chemotherapy and Radiation Therapy Response in Head and Neck Cancer. Annual Meeting of AAPM, Anaheim(2015).
  22. Y. Liu, T. Diwanji, B. Zhang, J. Zhuo, R. Gullapalli, R. Morales, W. D’Souza. Correlation of Tumor and Node Response to Concurrent Chemoradiation Therapy and Pharmacokinetic Parameters Derived From DCE-MRI in Locally Advanced Head and Neck Cancer. Int. J. Rad. Onco. Bio. Phys, 69(3), S179-S180 (2015).
  23. S. Chen, M. Guerrero, B. Zhang, B. Yi, S. Mossahebi, K. Prado, W. D'Souza, K. Langen. Implementation of a Non-Measurement-Based Patient-Specific IMRT QA Program. Annual Meeting of AAPM, Washington, D.C.(2016).
  24. C. Kalavagunta, X. Yang, H Xu , B. Zhang, S. Mossahebi , A. Sawant, B. Yi. Is Weekly MLC QA Necessary? Two Year EPID-Based Weekly MLC QA Experience at the University of Maryland. Annual Meeting of AAPM, Washington, D.C. (2016).
  25. S. Lee, S. Chen, B. Zhang, H. Xu, K. Prado, W. D’Souza, B. Yi. Is Geometry Based Setup Sufficient for All of the Head and Neck Treatment Cases?: A Feasibility Study Towards the Dose Based Setup. Annual Meeting of AAPM, Washington, D.C. (2016)

Research Interests

  • Informatics in radiation therapy
  • Knowledge-base decision science in clinical programs and automation in radiation therapy treatment planning
  • Proton Radiotherapy

Clinical Specialty Details

  • Quality assurance of therapeutic machines and equipment
  • Quality assurance of patient-specific treatment
  • Radiotherapy treatment planning system development
  • External beam therapy (photon/electron/proton) and Brachtherapy

Grants and Contracts

FUNDED RESEARCH PROJECTS

 

  • Project Title: the 2nd generation Fourier Transformation System (FTS-2) for Submillimetre Common-User Bolometer Array 2 (Scuba-2) in James Clark Maxwell Telescope (JCMT)
    • Funding Source: Natural Sciences and Engineering Research Council of Canada (NSERC)
    • Funding Amount: CA$1,624,282
    • PI: Dr. David Naylor
    • Project Timeline: 2002.1-2008.6
    • Project Objective: to develop a novel Fourier instrument to enhance the capacity of JCMT telescope for sky survey and dark matter.
    • Role: Co-Investigator
    • My responsibilities: leading the efforts in designing/developing/optimizing astronomical data reduction/ analysis/ calibration system for Scuba-2 project (James Clerk Maxwell Telescope) of Joint Astronomy Centre (http://www.roe.ac.uk/ukatc/projects/scubatwo/), and designing real-time control system for Scuba-2 and astronomical far-infrared spectroscopy analysis software, designing/developing astronomical data calibration for Herschel-Spire project (Herschel Space Observatory) of European Space Agency (http://herschel.esac.esa.int/).

 

  • Project Title: Image-Guided Adaptive Radiotherapy
    • Funding Source: National Cancer Institute (NCI)
    • Funding Amount: US$20,825,598
    • PI: Dr. Jeffrey Williamson
    • Project Timeline: 2007.4-2013.3
    • Project Objective: To investigate image-guided radiotherapy technology to enable safe delivery of more aggressive dose regimens through a combination of biological imaging for improved target delineation and implementation of an integrated and clinically practical system of image-guided adaptive radiation therapy (IGART).
    • Role: Co-Investigator
    • My responsibilities: leading the efforts in designing/developing computing infrastructure (medical image processing, registration and segmentation) for Image-Guided Adaptive Radiation Therapy (IGART).