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Sripriya Sundararajan, MBBS, M.D.

Academic Title:

Assistant Professor

Primary Appointment:

Pediatrics

Additional Title:

Neonatal Director of OB-MFM Relations

Location:

Paca-Pratt, 8-S-164

Phone (Primary):

410-328-6003

Fax:

410-328-1076

Education and Training

Sripriya Sundararajan is an Assistant Professor in the Division of Neonatology at University of Maryland. She joined the University Of Maryland School Of Medicine in August 2013. She originally received her MD in Pediatrics from Chennai Medical College, India after completing medical school from Stanley Medical College, India. She recertified in Pediatrics and completed her fellowship training in Neonatal-Perinatal Medicine from the University of Virginia. She is a member of the American Academy of Pediatrics, section member of Neonatal-Perinatal Medicine, member of the Society for Pediatric Research and member of the Eastern Society for Pediatric Research.

 

Biosketch

Dr. Sundararajan's research focuses on improving patient outcomes in preterm infants by reducing morbidities such as necrotizing enterocolitis and retinopathy of prematurity. Dr Sundararajan studies the impact of red blood cell (RBC) transfusions on preterm infants and the benefits of placental transfusion associated with delayed cord clamping. Dr Sundararajan has established standardized guidelines for blood product use including RBC and Platelet transfusions in the NICU in an effort to both reduce the use and the possible side-effects associated with transfusion in preterm newborns. She has led a multidisciplinary institutional effort to incorporate delayed cord clamping into clinical practice and has developed a transfusion protocol for our level IV NICU at the University of Maryland Medical Center (UMMC). 

Dr. Sundararajan is collaborating with the Institute for Genome Sciences at UMSOM to better understand intestinal permeability in very low birth weight infants through a non-invasive, accurate, cost-effective screening test. She is also actively involved in medical student and neonatology fellow education through participation as a preceptor for Introduction to Clinical Medicine -1 course, Pediatric Clerkship rotation and a Course Director for Pathophysiology to Neonatal-Perinatal fellows. As the Neonatal Director of OB-MFM relations, Dr Sundararajan facilitates consultation with high-risk pregnant mothers through working closely with the Maternal-Fetal Medicine group at UMMC.

Research/Clinical Keywords

Neonatal red blood cell transfusion, heavy metal exposure from blood transfusion, delayed cord clamping and study of intestinal permeability in very low birth weight infants

Highlighted Publications

Sundararajan S, Falck AJ, Al-Mudares F, Contag SA, and Bearer CF. Fetal exposure to mercury and lead from intrauterine transfusions. Pediatr Res.2019 Jun 19. doi:10.1038/s41390-019-0463-z. PMID: 31216568

Aghion, A., Falck, A. J., & Sundararajan, S. (2019). Case: Sudden unexpected collapse in a full term infant. NeoReviews. 2019 Dec;20(12):e744-e747. doi: 10.1542/neo.20-12-e744.PMID: 31792162

Lanlokun, M., Capriolo, C. M., Alexander, J. L., & Sundararajan, S. (2018). Case 2: Feeding Intolerance Following Topical Atropine Instillation in a Premature Infant. NeoReviews, 19(12), e765-e769.

Kochan, M. J., Freiden, T., Pyle, M., Isaiah, A., & Sundararajan, S. (2018). An Infant with Severe Stridor and Cyanosis at Birth. NeoReviews, 19(12), e783-e786.

Olayemi O. Ajayi, Natalie L. Davis, Bushra Saleem, Shiv Kapoor, Adora C. Okogbule-Wonodi, Rose M. Viscardi, and Sripriya Sundararajan: Impact of red blood cell transfusions on intestinal barrier function in preterm infants. J Neonatal-Perinatal Medicine, 2018 Nov 8. doi: 10.3233/NPM-1828 PMID: 30412507

Verde BL, Kaushal S, Slack MC, Sundararajan S. Venous-Arterial ECMO as a Vital Bridge for Survival in a Neonate with Cor-triatriatum Dexter. Ann Clin Case Rep. 2017; 2: 1409. ISSN: 2474-1655

*Sundararajan, Sripriya, Bearer,Cynthia,F. Epigenetics, the Environment, and Children's Health across Lifespans 1 ed. Hollar D, editor. Springer International Publishing Switzerland: 2016. Chapter 5, Role of environmental epigenetics in perinatal and neonatal development; p.pp 117-134. XXI, 386p.

Carrasco M, Rao SC, Bearer CF, *Sundararajan S. Neonatal Gabapentin Withdrawal Syndrome. Pediatr Neurol. 2015 Nov;53(5):445-7.doi: 10.1016/j.pediatrneurol.2015.06.023. Epub 2015 Jul 8. PubMed [citation] PMID: 26278632

*Sripriya Sundararajan, Allison M. Blatz, Dorr G. Dearborn, Arthur W. Varnes, Cynthia F. Bearer, and Dina El Metwally: Toxic metal contamination of banked blood designated for neonatal transfusion. Journal of Clinical Toxicology, Sept 2015. J Clin Toxicol 5:267. doi:10.4172/2161-0495.1000267

Luzina IG, Todd NW, Sundararajan S, Atamas SP.The cytokines of pulmonary fibrosis: Much learned, much more to learn. Cytokine. 2015 Jul;74(1):88-100.doi: 10.1016/j.cyto.2014.11.008. Epub 2014 Dec 24. Review. PubMed [citation] PMID: 25543535

*Sundararajan S, Dodhy SC, Pittman RN, Lewis SJ. Effects of non-leukocyte-reduced and leukocyte-reduced packed red blood cell transfusions on oxygenation of rat spinotrapezius muscle. Microvasc Res. 2014 Jan;91:30-6. doi: 10.1016/j.mvr.2013.10.005. Epub 2013 Nov 2. PubMed [citation] PMID: 24189119, PMCID: PMC4386583

*Sundararajan S, Gaston B. Sickle cell disease does not decrease pulmonary nitric oxide. J Pediatr. 2012 Jan;160(1):6-7. doi: 10.1016/j.jpeds.2011.08.024. Epub 2011 Sep 14. PubMed [citation] PMID: 21924434

Additional Publication Citations

Published Multimedia

Sundararajan, Sripriya: Upper Airway Obstruction In The Newborn. Organization of Neonatal-Perinatal Medicine Training Program Directors' National Neonatal Flipped Classroom Program. American Academy of Pediatrics, 2019.

Research Interests

Dr. Sundararajan's major research interests include:

  1. Study the impact of heavy metal exposure from in-utero blood transfusion to the developing fetus 
  2. Study the impact of red blood transfusions on intestinal barrier function in preterm infants
  3. Delayed Cord Clamping in preterm neonates not requiring immediate resuscitation 
  4. Study association between RBC transfusion and clinical outcomes, including Retinopathy of Prematurity and NEC in ELBW infants.

Clinical Specialty Details

Dr Sundararajan specializes in Neonatal-Perinatal Medicine. 

 

Awards and Affiliations

Mentor recognition award from the University Of Maryland School Of Medicine and Office of Student Research for transformational impact on medical students (2017, 2018, 2019)

Grants and Contracts

09/16/2019 – 06/30/2021   Sundararajan* (Co-Inv, 5%; PI – B. Ma)

                                           "Role of short chain fatty acids in intestinal barrier maturation in preterm

                                           infants"

                                           R 21 NIH grant

                                          *Responsible for IRB protocol, enrollment of subjects, data collection, and

                                           contribution to dissemination of results

 

01/01/2019 – 12/31/2021   Sundararajan* (Co-Inv, 5%; PI – B. Ma)

                                             "An accurate, non-invasive discriminatory screening test for rapid detection of

                                           elevated intestinal permeability in preterm infants”

                                           Gerber Foundation Grant

                                           *Responsible for IRB protocol, enrollment of subjects, data collection, and

                                           contribution to dissemination of results

In the News

Dr Sundararajan regularly mentors medical students as part of Foundation of Research and Critical Thinking (FRCT). For two consecutive years (2015 and 2016), Dr Sundararajan’s mentored medical students have won the first prize for poster presentation at the 38th and 39th annual medical student research day at University Of Maryland School Of Medicine.

Community Service

Dr Sundararajan is the faculty representative from the Division of Neonatology at UMSOM for the quarterly Section on Neonatal Perinatal medicine (SONPM) newsletter. She is actively involved with both the submission and dissemination of the quarterly section newsletter and the “Articles of Interest” monthly content from SONPM to the Division of Neonatology.

Dr Sundararajan was the physician representative for "Howard County Drug Free" initiative at Mt. Hebron High School 2017-2019. 

Professional Activity

Medical Student Education:

Dr Sundararajan regularly mentors medical students as part of the Foundations of Research and Critical Thinking (FRCT). Dr Sundararajan is also the faculty mentor for Lois Young-Thomas House of the Core Mentoring Group geared towards medical student career advancement at the University of Maryland School of Medicine. She promotes advising and mentoring for medical students across all four years of medical school, assist students with career development, encourages students to serve as peer advisors and role models for other students and develop a community of support and mentorship for those dedicated to education.

Dr Sundararajan serves as a preceptor for the Introduction to Clinical Medicine-1 course offered to first year medical students and as Teaching Attending for third year medical students during their Pediatric Clerkship rotations.

Neonatology Fellow Education:

Dr Sundararajan is the Course Director for the pathophysiology curriculum at the University of Maryland Neonatal-Perinatal fellowship program. She has participated with the National Neonatology Curriculum to support educational efforts through flipped classroom guides from Minute CE program to benefit neonatology fellows.

Dr Sundararajan is the  faculty representative from the Division of Neonatology at UMSOM for the quarterly Section on Neonatal Perinatal medicine (SONPM) newsletter. She is involved with both the submission and dissemination of the quarterly section newsletter and the “Articles of Interest” monthly content from SONPM to all the Neonatology faculty and house staff. 

Links of Interest