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Steven M. Scharf, MD, PhD

Academic Title:

Clinical Professor

Primary Appointment:

Medicine

Additional Title:

Director, Sleep Disorders Center (Adults)

Phone (Primary):

(410) 706-4771

Fax:

(410) 706-0345

Education and Training

University of Rochester, AB, 1964-1968, Biology

Johns Hopkins University School of Medicine, 1968-1973, MD 

Johns Hopkins University School of Public Health, PhD, 1969-1973,  Environmental Medicine

Biosketch

Positions and Employment

1973-1975Medical Residency Peter Bent Brigham Hospital

1975-1978Pulmonary Fellowship Peter Bent Brigham Hospital

1978-1979Instructor in Medicine, Harvard Medical School, Boston, MA

1978-1980Research Associate, VA Medical Center, West Roxbury, MA

1979-1980Assistant Professor of Medicine, Harvard Medical School, Boston, MA

1980-1984Senior Lecturer in Medicine, Ben-Gurion University of the Negev, Faculty of Health Sciences, Beersheba, Israel

1984-1988Assistant Professor of Medicine, Harvard Medical School, Boston, MA

1989-1995Associate Professor of Medicine, Albert Einstein College of Medicine, Bronx, NY

1996-2002Professor of Medicine, Albert Einstein College of Medicine

1997Adjunct Professor of Medicine, Columbia University

2002Professor of Medicine with Tenure, University of Maryland

2002, Medical Director, Sleep Disorders Center, University of Maryland.

Other Experience and Professional Memberships

1980 - 1984Director, Division of Lung Diseases, Soroka Medical Center, Beersheba, Israel

1989 - 2002Section Head, Pulmonary and Critical Care Research Long Island Jewish Medical Center

1998 - 2002          Associate Chairman of Medicine for Academic Affairs, Long Island Jewish Medical Center

2002 -                   Director, Sleep Disorders Center, University of Maryland

1978 -                   American Thoracic Society

1978 -                   American Physiological Society

1999 -                   American Academy of Sleep medicine – Fellow

1996 -    2002       Steering Committee, National Emphysema Treatment Trial (NIH/NHLBI)

1999 -    2002       Steering Committee, Feasibility of Retinoids in Treatment of Emphysema Trial (NIH/NHLBI)

2000 -    2002       Steering Committee, Asthma Clinical Research Center Network (ALA)

2003 -                   Steering Committee, COPD Clinical Research Network (CCRN) of NIH

Honors

1968                      Phi Beta Kappa, University of Rochester

1972                      Alpha Omega Alpha, Johns Hopkins Medical School

1978                      Recipient of V.A. Career Development Award, Veterans Administration

Research/Clinical Keywords

Research interests keywords: Sleep in obstructive lung disease, health care utilization with sleep disturbances Clinical interests keywords: Sleep disorders, sleep breathing disorders

Highlighted Publications

Selected from over publications over 5 years:

  1. Geiger-Brown J, Rogers VE, Trinkoff AM, Kane RL, Bausell RB, Scharf SM.  Sleep, Sleepiness, Fatigue, and Performance of 12-hour shift nurses.  Chronobiology International, 2012, 29(2): 211-219.  PMID 22324559

  2. Greenberg-Dotan S, Reuveni H, Tal A, Oksenberg A, Cohen A, Shaya FT, Tarasiuk A, Scharf SM.  Increased Prevalence of Obstructive Lung Disease in Patients with Obstructive Sleep Apnea.  Sleep and Breathing, 2014; 18: 69 - 75; PMID 23733255.

  3. Romem A, Romem A, Koldobskiy D, Scharf SM. Diagnosis of obstructive sleep apnea using pulse oximeter derived photoplethysmographic signals.  J Clin Sleep Med 2014; 10: 285 - 290.

  4. Geiger-Brown J, Lindberg S, Krachman S, McEvoy C, Criner GJ, Connett JC, Albert RK, Scharf SM.  Self-reported sleep quality and acute exacerbations of chronic obstructive pulmonary disease.  Int J COPD 2015; 10: 389 – 397.  PMID: 25759571

  5. Korotinsky A, Assefa SZ, Diaz Abad M, Wickwire E, Scharf SM.  Comparison of American Academy of Sleep Medicine (AASM) versus Center for Medicare and Medicaid Services (CMS) Polysomnography (PSG) scoring rules on AHI and eligibility for Continuous Positive Airway Pressure (CPAP) treatment. Sleep and Breathing 2016, doi:10.1007/s11325-016-1327-y; PMID:26969658

Additional Publication Citations

Recent Chapter:

  1. Greenberg H, Lakticova V, Scharf SM. Pathophysiology, Clinical Features and Evaluation of Obstructive Sleep Apnea.  Kryger MH, Roth T, Dement WC, et al.  Principles and Practice of Sleep Medicine, 6th ed.  2016: Chapter 114: 1110 – 1124. Elsevier, Philadelphia, PA. 

    1. Shaya FT, Breunig IM, Scharf SM.  The use of age-period-cohort analysis to determine the impact of economic development on COPD mortality in Hong Kong.  Exp Rev Pharacoeconomics and Outcomes Res.  2012; 12: 19-21. PMID 22280192

    2. Assefa SZ, Diaz-Abad M, Wickwire EM, Scharf SM.  The functionsof sleep. AIMS Neuroscience.  2015; 2: 155 – 171. Open Access journal.

    1. Wickwire EM, Shaya F, Scharf SM.  Health economics of insomnia treatment: The return on investment for a good night’s sleep.  Sleep Med Rev. 2015 Nov 28;30:72-82. doi: 10.1016/j.smrv.2015.11.004. [Epub ahead of print]; 2016; 30: 72 – 82. PMID 26874067.

      Recent abstracts:

      Assefa S, Diaz-Abad M, Scharf SM.  Comparison of a simple sleep apnea screening device with standard in-lab polysomnography.  Sleep (abstracts) 37; 2014: A132.

      A159.  Tom SE, Brandt N, Scharf SM, Geiger-Brown J, Guralnik JM, Hale LE, Stone K, Shah NA, LaCroix AZ.  Patterns of sleep aid use in older American women.  Sleep (abstracts) 37; 2014: A346.

      A160.  Tom SE, Scharf SM, Brandt N, Geiger-Brown J, Guralnik JM, Hale LE, Li W, Womak CR, Zaslavsky O, LaCroix AZ.  Sleep aid use and physical function in older American Women.  Sleep (abstracts) 37; 2014: A347.

      A161.  Short B, Scharf SM, Netzer G, Graves A, Shanholtz C.  Ventilatory patterns in healthy subjects using high flow cannula nasal oxygen and continuous positive expiratory pressure (CPAP).  Am J Resp Crit Care Med (abstracts); 2014; 189: abstract A1177.

      A162.  Geiger-Brown J, Scharf SM, Krachman SL, McEvoy C, Harnden S, Criner CJ.  Sleep quality in patients with moderate to severe COPD.  Am J Resp Crit Care Med (abstracts); 2014: 189: A5816.

      A163.   Reed RM, Dransfield M, Miller M, Mitchell B, Pavlovich M, Scharf S, Shuldiner AR, Netzer Gender and the health effects of environmental tobacco smoke: A study of the old order Amish.  Spring meeting ATS.

      A164.   Zahdi ZH, Scharf SM, Pae E, Chen L.  Prenatal intermittent hypoxia affects body growth and cardiovascular function in rats.  Sleep 2015; 38: A14

      A165.   Riar R, Al Fouzan W, Altememi N, Cohen L, Diaz-Abad M, Scharf SM.  Efficacy of screening for obstructive sleep apnea in a general dental practice.  Sleep 2015; 38: A198.

      A166.   Altememi N, Assefa S, Riar R, Diaz-Abad M, Scharf SM.  Prediction of early CPAP compliance.  Sleep 2015; 38: A200.

      A167.   MulliganMJ, Eberlein M, Dransfield M, Netzer G, Sanchez PG, Scharf SM, Sin D, Celli BR, Reed RM.  Survival of lung transplant candidates with COPD: BODE reconsidered.  Spring meetings, American Thoracic Society, San Francisco 2006.

      A168.   Johnson BP, Scharf SM, Westlake KP.  Targeted memory reactivation during sleep, but not wake, improves sensorimotor, skill learning in healthy young adults. Spring meetings, World Congress for Neurorehabilitation (WCNR), Philadelphia, 2016. 

Research Interests

All aspects of sleep disorders especially effects of sleep-breathing disorders on health.

This includes animal models of sleep apnea - we have described myocarcial oxidant stress and dysfunction in rats exposed to chronic intermittent hypoxia

 

Clinical Specialty Details

All aspects of sleep disorders.

Grants and Contracts

2003 – 2004  Maryland Tobacco Restitution fund: Infliximab treatment in COPD.  Role on project: Principal investigator.  Direct costs: $75,000.  No indirect costs. 

2003 – 2004  American Lung Association: Effects of Chronic Intermittent Hypoxia on oxidative stress and proinflammatory cytokines in rats. Role on project: Principal Investigator. Direct costs: $10,000, Indirect Costs: NA

2002  - 2006  Cardiovascular Stress of Sleep Apnea and Heart Failure. HL071506 (Schwartz) Role on Project: Co-investigator. Direct Costs: $250,000 

2003 – 2008  National Institutes of Health: Evaluation of Home Asthma Telemanagement in COPD. R01 HL071690.  Role on Project: Co-investigator.  Direct Costs: $425,958

2006-2008  American Heart Association:  Oxidative Stress and Myocardial Function in a rodent model of sleep apnea.  AHA 0655487U. Role on project: PI.  Direct Costs: $120,000.  Indirect costs: $12000.

2003 – 2011  National Institutes of Health: Clinical Center – COPD Clinical Research Network.  HL074441,  Role on project: Principal investigator.  Direct Costs: $3,000,000, Indirect Costs: $957,875.  Total Costs: $3,957,875

2007 - 2015  National Institutes of Health: Long-term oxygen treatment trial.  HR76190;   Role on project: Co-PI of the Mid-Atlantic LOTT consortium (Criner, Temple PI).  Capitation

In the News

Recent article in Baltimore magazine (issue awarding the "best docs") .Profiled our sleep center and myself.

Several appearances on local and national news.  Most recently WNBC Washington - profiled the sleep lab and sleep patients.

Professional Activity

Certifications 

1974, National Board of Medical Examiners – Diplomate; certificate #127549

1977American Board of Internal Medicine, Internal Medicine Specialty; certificate  #56059

1978American Board of Internal Medicine, Certification in Subspecialty of Pulmonary Diseases; certificate #56059

1980Scientific Council of Israel, Certification in Specialty of Lung Diseases; certificate #54900

1989-1999American Board of Internal Medicine, Certification in Critical Care; certificate  #56059

2000American Board of Sleep Medicine - Certification in Sleep Medicine (Diplomate); certificate #1482

Medical Licensures

1980State of Israel  #54900

1988New York State  #175385 (inactive status since 2002)

2002State of Maryland #D0058344

Employment History

Academic Appointments     

1978–1979      Instructor in Medicine Harvard Medical School, Boston, MA

1978-1980       Research Associate, VA Medical Center, West Roxbury, MA

1978-1980       Junior Associate in Medicine, Peter Bent Brigham Hospital,Boston, MA

  1. Assistant Professor of Medicine, Harvard Medical School, Boston, MA

    1980-1984Senior Lecturer in Medicine, Ben-Gurion University of the Negev, Faculty of Health Sciences, Beersheba, Israel

    1986Visiting Professor University of Toronto School of Medicine

    1984-1988Assistant Professor of Medicine, Harvard Medical School, Boston, MA

    1989-1995Associate Professor of Medicine, Albert Einstein College of Medicine, Bronx, NY

    1992Visiting Professor, University of Toronto School of Medicine

    1994Visiting Professor, Ben-Gurion University of the Negev, Beersheba, Israel

    1996 - 2002Professor of Medicine, Albert Einstein College of Medicine

    1996Dozor Visiting Professorship, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev (1 month honorary visiting professorship)

    1997Adjunct Professor of Medicine, Columbia University

    2002Professor of Medicine with tenure – University of Maryland, School of Medicine

    2008Visiting Professor of International Medicine, Ben-Gurion University of the Negev                 

    Professional Society Memberships 

    Examiner, Israel Medical Association Scientific Council,

    Pulmonary Diseases Specialty Certification 1982 –1984

    Member, Board of Directors, Israel Society for Clinical Investigation 1982 - 1984

    American Thoracic Society 1978 -

    American Physiological Society 1978 -

    Israel Society of Chest Physicians 1980 - 1984

    Israel Society for Physiology and Pharmacology 1982 - 1984

    Israel Society for Clinical Investigation  1980 - 1984

    American Heart Association- Cardiopulmonary Council  1984 -

    American Association for the Advancement of Science  1988 -

    Society for Critical Care Medicine 1988 -

    American Academy of Sleep medicine – Fellow 1999 -

    New York Society of Sleep Medicine  1999 -