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Aruna Panda, BVSc, PhD, MPH

Academic Title:

Associate Professor

Primary Appointment:


Secondary Appointment(s):

Epidemiology & Public Health


MSTF, G-100

Phone (Primary):

(410) 706-8542


(410) 706-8538

Education and Training

  • BVSc (Bachelor of Veterinary Science): 1996, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India
  • MS: Virology, 1999, University of Arkansas, Fayetteville Arkansas
  • PhD: Molecular Virology, 2004, University of Maryland, College Park, Maryland
  • MPH: Global Health and Infectious Diseases, 2008, University of Maryland, Baltimore, Maryland


Infectious disease research has always fascinated me and I have, since a long time, been interested in research directed towards improved understanding of basic and molecular biology, pathology, immunology and pathogenic mechanisms of disease-causing organisms. After completing my degree in Bachelor of Veterinary Science (B.V.Sc.) from India in 1996, I joined the University of Arkansas (UA) in Fayetteville in 1997, to pursue a Master’s degree program in Virology. My research at UA focused on understanding the molecular basis of pathogenesis of reoviruses. I then furthered my education in Virology by joining a Ph.D. degree program in Molecular Virology at the University of Maryland in College Park (UMCP) in 1999.

My research at UMCP was focused towards understanding the role of a specific protein of the Newcastle Disease Virus in virulence and exploring its potential in vaccine development. Data obtained from this research has been published in peer-reviewed journals. One such publication (Panda, et. al. Microbial Pathogenesis. 2004.) was listed among the Top 25 articles downloaded in Science Direct in 2005. My interest in public health lead me to further pursue my education in Global Health and Infectious Diseases and I joined the Master’s in Public Health (M.P.H.) program in the Department of Epidemiology and Public Health at UMSOM in 2004 and obtained a M.P.H. degree in 2008. My MPH Capstone Project was focused towards the epidemiology of the pandemic H5N1 avian influenza virus and its impact on global public health.

I joined the Program of Comparative Medicine in the Department of Pathology at the UMSOM in 2004. As a research veterinarian and faculty member my duties include conducting research, as well as carrying out administrative, teaching and clinical activities. The major goals of my research projects are focused on characterization of animal models of human disease for biomedical research and use of such models to advance understanding of disease or biological processes. My areas of expertise are in the fields of Veterinary Medicine, Virology, Infectious Diseases and Global Public Health. I am involved in projects which are related to developing vaccines and other innovative therapeutics against infectious agents such as Shigella dysenteriae 1, Escherichia coli O157:H7, Escherichia coli O104:H4, Salmonella typhimurium, avian influenza and measles.

Additionally, I am also interested in projects related to applying immunological methods of tolerance induction to prevent rejection of allografts in composite tissue transplantation. As a faculty member at UMSOM my teaching responsibilities include providing lectures to undergraduates, graduates and medical students in areas related to global public health, epidemiology, infectious diseases and vaccine development. Overall, my research interests focus on infectious disease research and development of animal models for understanding human diseases.

Research/Clinical Keywords

Vaccine development, global health and infectious diseases

Highlighted Publications

Panda, A., Huang, Z., Elankumaran, S., Rockemann, D. D., and Samal, S. K. Role of fusion protein cleavage site in the virulence of Newcastle disease virus. Microbial Pathogenesis. 36(1): 1-10. 2004.

Panda, A., Elankumaran, S., Krishnamurthy, S., Huang, Z., and Samal, S.K. Loss of N-linked glycosylation from the hemagglutinin-neuraminidase protein alters virulence of Newcastle disease virus. Journal of Virology. 78(10): 4965-4975. 2004.

Zangari, T., Melton-Celsa, A., Panda, A., Boisen, N., Smith, M., Taratov, I., DeTolla, L.J., Nataro, J.P. and O'Brien, A.D. Virulence of the Shiga toxin type 2-expressing Escherichia coli O104:H4 German outbreak isolate in two animal models. Infection and Immunity.February 2013. doi: 10.1128/¿IAI.01310-12.

Seekatz, A.M., Panda, A., Rasko, D.A., Toapanta, F. R., Eloe-Fadrosh, E. A., Khan, A.Q., Liu, Z., Shipley, S. T., DeTolla, L.J., Sztein, M.B., and Fraser, C.M. Differential Response of the Cynomolgus Macaque Gut Microbiota to Shigella Infection. PLoS ONE. 2013. Jun 5;8(6):e64212. doi: 10.1371/journal.pone. 0064212. PMID: 23755118.

Panda, A., Tatarov, I, Masek, B.J., Hardick, J., Crusan, A., Wakefield, T., Carroll, K., Yang, S., Hsieh, Y.H., Lipsky, M.M., McLeod, C.G., Levine, M.M., Rothman, R.E., Gaydos, C.A. and DeTolla, L.J. A rabbit model of non-typhoidal Salmonella bacteremia. Comparative Immunology, Microbiology and Infectious Diseases.July 2014. DOI: 10.1016/j.cimid.2014.05.004.

Additional Publication Citations

Huang, Z., Krishnamurthy, S., Panda, A., and Samal, S. K. High-level expression of a foreign gene from the 3-prime proximal first locus of a recombinant Newcastle disease virus. Journal of General Virology. 182:1729-1736. 2001.

Huang, Z., Elankumaran, S., Panda, A. and Samal, S. K. Recombinant Newcastle disease virus as a vaccine vector. Poultry Science. 82:899-906. 2003.

Huang, Z., Krishnamurthy, S., Panda, A., and Samal, S. K. Newcastle disease virus V protein is associated with viral pathogenesis and functions as an alpha interferon antagonist. Journal of Virology. 77 (16): 8676-8685. 2003.

Huang, Z., Panda, A., Elankumaran, S., Rockemann, D. D., and Samal, S. K. The hemagglutinin-neuraminidase protein of Newcastle disease virus determines tropism and virulence. Journal of Virology. 78(8): 4176-4184. 2004.

Silverman, R.P., Banks, N.D., DeTolla, L.J., Shipley, S.T., Panda, A., Sanchez, R.A., Azimzadeh, A.M, Pierson, R.N., Wang, D., Rodriguez, E.D, Holton, L.H., and Bartlett, S.T. A Heterotopic Primate Model for Facial Composite Tissue Transplantation. Annals of Plastic Surgery. 60(2): 209-216. 2008.

Stanwix, M.G., Nam, A.J., Rodriguez, E.D., Drachenberg, C., Bluebond-Lagner, R., Panda, A., Shipley, S.T., Bartlett, S.T. and Barth, R.N. Histological mild rejection does not correlate with clinical rejection or graft survival in primate composite facial allografts. American Transplant Congress. 2008.

Nam, A.J., Stanwix, M.G., Rodriguez, E.D., Kukuruga, D., Drachenberg, C., Bluebond-Lagner, R., Panda, A., Shipley, S.T., Bartlett, S.T. and Barth, R.N. Prolonged survival of composite facial allografts in non-human primates and development of donor-derived post-transplant lymphoproliferative disorders. American Transplant Congress. 2008.

Rao, S., Kong, W-P., Wei, C-J., Yang, Z-Y., Nason, M., Styles, D., DeTolla, L.J., Panda, A., Sorrell, E.M., Song, H., Wan, H., Ramirez-Nieto, G.C., Perez, D., and Nabel, G.J. Multivalent HA DNA Vaccination Protects against Highly Pathogenic H5N1 Avian Influenza Infection in Chickens and Mice. Public Library of Science One. 3(6): e2432. 2008.

Khattar, S.K., Yan, Y., Panda, A., Collins, P.L., and Samal, S.K. A Y526Q Mutation in the Newcastle Disease Virus HN Protein Reduces Its Functional Activities and Attenuates Virus Replication and Pathogenicity. Journal of Virology. 83(15): 7779-7782. 2009.

Panda, A., Samal, S. K., and DeTolla, L.J. Avian Influenza: An Emerging Global Threat. Indian Journal of Poultry Science. 44 (2):143-153. 2009.

Shipley, S.T.*, Panda, A*, Khan, A.Q. *, Kriel, E. H., Maciel, M. Jr., Livio, S., Nataro, J.P., Levine, M.M., Sztein, M. B.§ and DeTolla, L. J.§ A challenge model for Shigella dysenteriae 1 in cynomolgus monkeys (Macaca fascicularis). (* denotes equal contribution of the authors towards the completion of this study and § denotes equal contribution of the authors to the direction of this work presented in the manuscript). Comparative Medicine. 60(1): 54-61. 2010.

Panda, A., Tatarov, I., Melton-Celsa, A. R., Kolappaswamy, K., Kriel, E.H., Petkov, D, Coksaygan, T., Livio, S., McLeod, C.G., Nataro, J.P., O'Brien, A.D., and DeTolla, L.J. Escherichia coli O157:H7 infection in Dutch Belted and New Zealand White rabbits. Comparative Medicine. 60(1): 31-37. 2010.

Tatarov, I., Panda, A., Petkov, D., Kolappaswamy, K., Thompson, K., Kavirayani, A., Elson, E., Davis, C., Martin, S.S., and DeTolla, L.J. Effects of Magnetic Fields in Tumor Growth and Viability. Comparative Medicine. 61(4): 339-345. 2011.

Barth, R.N., Rodriguez, E.D, Mundinger, G.S., Nam, A. J., Ha, J.S., Hui-Chou, H., Jones, L.S., Panda, A., Shipley, S.T., Drachenberg, C.B., Kukuruga, D., and Bartlett, S.T. Vascularized Bone Marrow Based Immunosupression Prevents Rejection of Composite Allografts in Non-Human Primates. American Journal of Transplantation. 11:1407-1416. 2011.

Mundinger, G.S., Nam, A.J., Hui-Chou, H.G., Stanwix, M.G.,Jones, L.S., Drachenberg, C.B., Kukuruga, D., Shipley, S.T., Dorafshar, A.H.,Panda, A., Bartlett, S.T., Barth, R.N., and Rodriguez, E.D. Non-Human Primate Model of Fibula Vascularized Composite Tissue Allotransplantation Demonstrates Donor-recipient Bony Union. Plastic and Reconstructive Surgery. 2011. Aug 11 [Epub ahead of print]

Zangari, T., Melton-Celsa, A., Panda, A., Smith, M., Taratov, I., DeTolla, L.J., and O'Brien, A.D. Enhanced virulence of the Escherichia coliO157:H7 spinach-associated outbreak strain in two animal models is associated with higher levels of Stx2 production after induction with ciprofloxacin. Infection and Immunity. September 15 2014. IAI.02361-14. PMID: 25225244. 

Khattar, S.K., DeVico, A.L., LaBranche, C.C., Panda, A.,Montefiori, D.C., and Samal, S.K. Enhanced Immune Responses to HIV-1 Envelope Elicited by Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140Proteins. Journal of Virology. 2015. November 18; 90(3): 1682-6. doi: 10.1128/JVI.02847-15.

Panda, A., Nagaraj, S., Zhao, X., Tettelin, H. and DeTolla, L.J. Complete Genome Sequences of Mycobacterium kansasii Strains Isolated from Rhesus Macaques. Genome Announcements. 2017 Apr 20;5(16). pii: e00187-17. doi: 10.1128/genomeA.00187-17.

Research Interests

My research interests are focused towards understanding the molecular basis of pathogenesis of RNA viruses, and conducting research towards the development of improved vaccines. Research focus on developing and characterizing animal models of human disease for biomedical research and use of such models to understand disease pathogenesis leading to development of innovative therapeutics. Keen interest in the areas of public health and epidemiology with studies focused towards understanding the global burden of infectious diseases in developing countries.

Clinical Specialty Details

Veterinary Medicine, Virology, Global Health and Infectious Diseases.

Awards and Affiliations


2002                    David B. Snyder Graduate Student Research Award at theUniversity of Maryland, College Park, MD.

2002                    Student Travel Grant Award for the 21st Annual American Society for Virology Meeting, University of Kentucky, Lexington, KY.

2003                    Marcie Becker Graduate Student Scholarship for Outstanding Research at the University of Maryland, College Park, MD.

2004                    Student Travel Grant Award for the 22nd Annual American Society  for Virology  Meeting, University of California, Davis, CA.

2008                    Outstanding Alumnus Early Career Award by the College of Agriculture and Natural Resources at the University of Maryland, College Park, MD.

Professional Memberships/Affiliations

Member, American Society for Virology (ASV)

Member, American Veterinary Medical Association (AVMA)

Contributing Member, American Public Health Association (APHA)

Member, Infectious Diseases Society of America (IDSA)

Member, National Academy of Veterinary Sciences (NAVS), India.

Member, American Association of Laboratory Animal Science (AALAS)

Member, Association of Primate Veterinarians (APV) 

Grants and Contracts

Ongoing grants/contracts:

1U19AI109776-01 Myron M. Levine (PI) 03/01/2014-02/28/2019


The Enteric Center of Excellence for Translational Research-Enteric CETR proposal.

Evaluate immunoprophyllactic measures against emerging enteric infections.

Role: Co-investigator

W81XWH-13-2-0056 Stephen Bartlett (PI) 09/15/13-09/14/17

W81XWH-12-CRMPR-RTR Department of Defense

Upregulation of bone marrow compartment-mediated immunomodulation for vascularized composite allografts.


W81XWH-13-AFIRM-IIRP PIs: Rolf Barth, Stephen Bartlett, Branco Bojovic 09/18/13-09/17/18

Sponsor award# (Sub award from Wake Forest U):

WFUHS441040 CTA-10

Vascularized bone marrow regulates alloresponses to vascularized composite allografts.


UM Ventures Seed Grant Program PI: Louis DeTolla 05/01/2016-05/01/2017

Assessment of a low-ammonia, one-month change frequency microisolator cage prototype for housing research mice.

Role: Co-Investigator

Completed grants/contracts:

N00014-04-1-0125 Bartlett (PI) 2010-2012

Department of Defense

Chimerism and Tolerance in Composite Tissue Transplantation.

Role: Co-investigator.

2U54A1057168-08 Levine (PI) 03/01/2009-02/282014

National Institutes of Health/NIAID

Middle Atlantic Regional Center of Excellence for Biodefense and Emerging Infectious Diseases (MARCE)

Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Research (Non-human Primate Core)

Role: Co-investigator

2R37A1020148-26AI DeTolla (PI) 06/23/08-05/31/2012

NIAID/Uniformed Services University of Health Sciences (USUHS)

Henry Jackson Foundation

Pathogenicity of Shiga-toxin producing E.coli.

Role: Co-PI

2R37AI020148-28(Supplement) DeTolla (PI) 2008-2012


Pathogenicity of Shiga-toxin producing E.coli.

Role: Co-PI

U19 AI082655-01 Sztein, MB (PI) 06/01/09-05/31/14

CCHI Research Project 1

Identify the immunological mechanisms that mediate effective protection from shigellosis following vaccination and natural infection with Shigella dysenteriae 1 in cynomolgus macaques.

Role: Co-Investigator

5R37A1020148-29 DeTolla, Louis (PI) 2012-2013

NIAID/Henry M. Jackson Foundation for the Advancement of Military Medicine

Pathogenicity of Shiga Toxin Producing E.coli

Role: Co-PI

A1-02-031 Levine, Myron (PI) 09/04/03 – 12/31/07


Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Research (Non-human Primate Core)

Role: Co-investigator

27XS065 DeTolla, Louis (PI) 2/27/07-9/30/07

NIH/NIAID, Awarding Agency: SAIC, Frederick

Vaccine Development for Avian Influenza

Role: Co-PI

MAES-NIH-003 Samal, Siba K. (PI) 9/01/07-8/31/08

NIH-Maryland Agricultural Experimental Station (MAES)

Avian Metapneumovirus as a Vectored Vaccine for Highly Pathogenic Avian Influenza Virus.

Role: Co-PI

S10RR022434 DeTolla, Louis (PI) 03/1/06 – 02/28/07

National Center for Research Resources Xenogen IVIS-200 Small Animal Imaging System

Shared Instrumentation Grant

Role: Co-Investigator

N00014-08-1-0766 Bartlett (PI) 2008-2010

Department of Defense

Composite Tissue Transplantation for civilian and combat casualties.

Role: Co-Investigator

VICH GL 43 Detolla, Louis (PI) 08/01/07-07/31/11

Maryland Industrial Partnerships (MIPS)

New Drug for Animal Medicine-Development of a time-release buprenorphine.

This GLP/FDA regulated project studies the toxicity of a time-released analgesic in mice.

Role: Co-Investigator