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Erin E. O'Connor, MD

Academic Title:

Assistant Professor

Primary Appointment:

Diagnostic Radiology and Nuclear Medicine

Phone (Primary):

(410) 328-1293

Education and Training

University of Notre Dame, Notre Dame, Indiana
College of Arts and Letters, Bachelor of Arts, May 1995
Magna Cum Laude

SUNY Health Science Center at Syracuse, College of Medicine
Syracuse, New York
Doctor of Medicine, May 1999

University of Chicago, Department of Internal Medicine
Chicago, Illinois
Intern, June 1999 – July 2000

University of Chicago, Department of Radiology
Chicago, Illinois
Resident, July 2000 – June 2004

Northwestern University Medical Center, Section of Neuroradiology
Chicago, Illinois
Fellow, July 2004 – June 2005


Erin O’Connor, M.D. received her medical degree from SUNY Health Sciences Center at Syracuse, College of Medicine, completed an internship at the University of Chicago, Department of Internal Medicine, a residency in the Department of Radiology, University of Chicago and a fellowship in Neuroradiology at Northwestern University Medical Center. Prior to joining the department, Dr. O’Connor served on the faculty at the Lewis Katz School of Medicine at Temple University as an Associate Professor of Neuroradiology. Dr. O’Connor is the Principal Investigator of Brain Structure and Functional Connectivity in HIV Infection, Bridge Program Award from the Office of the Vice President for Research Administration (OVPR) at Temple University. At the UMSOM she is establishing the Laboratory of Translational Neuroradiology (LANTERN) to explore the utility of using structural and functional neuroimaging biomarkers to predict disease course and response to therapy in a range of conditions. Specific projects will include: 1) MRI predictors of cognitive decline in treated HIV infection, 2) multimodal neuroimaging biomarkers predicting stroke risk in chronic renal disease, and 3) participation in the multi-site European clinical RESSTORE trial aimed at determining neuroimaging biomarkers predicting response to mesenchymal stem-cell treatment of ischemic stroke. All of these projects will combine the use of advanced multimodal neuroimaging techniques in a personalized medicine framework, ultimately allowing individualized prediction of subsequent clinical course or response to therapy.

Research/Clinical Keywords

Neuroimaging, Neuroradiology, HIV infection, Stroke

Highlighted Publications

O'Connor EE, Chen P, Anderson R, Weston B, Zeffiro TA, Ahmed A, Zeffiro TA. Gender Trends in Academic Radiology Publication in the United States Revisited. Academic Radiology, in press

O’Connor EE, Zeffiro TA, Zeffiro TA. Brain Structural Changes Following HIV Infection: Meta-analysis. American Journal of Neuroradiology, January 2018.

O’Connor EE, Jaillard A, Renard F, Zeffiro TA. Brain Microstructural Changes in HIV Infection: A Meta-analysis and Confirmation Study. American Journal of Neuroradiology, August 2017.

De Patre D, Van de Winckel A, Panté F, Rizzello C, Zernitz M, Mansour M, Zordan L, Zeffiro T, O’Connor E, Bisson T, Lupi A, Perfetti C. A Case Report of Visual and Motor Recovery after Cognitive Sensorimotor Rehabilitation (Perfetti’s Method) in a Patient with Cortical Blindness. Journal of Neurologic and Physical Therapy, July 2017.

Chapman T, Reid J, O’Connor EE.  The Importance of Combined Teaching Methods is Radiology Resident Education. Academic Radiology, June 2017.

Chapman T, Reid J, O’Connor EE.  Anonymity and Electronics: Adapting Preparation for Radiology Resident Examination. Academic Radiology, March 2017.

O’Connor EE, Cousar M, Lentini JA, Castillo M, Zeffiro TA.  Efficacy of Double-blind Peer Review in a Subspecialty Journal. American Journal of Neuroradiology, February 2017.

O’Connor EE, Fried J, McNulty N, Shah P, Hogg JP, Lewis P, Zeffiro T, Agarwal V, Reddy S.  Flipping Radiology Education Right Side Up.  Academic Radiology, July 2016.

Cunningham R, Shah PS, Carabelli E, Barakat N, O’Connor E, Luo JJ.  3D MRI - Diagnostic, Dynamic and Diffusion Tensor Evaluation of Hirayama Disease. Neurological Cases, April 2014, 1:4-7.

Curran, JG, O’Connor E,  Imaging of CraniopharyngiomaChilds Nervous System, August 2005, 21:635-639.

O’Connor EE, Dixon, LB, Peabody, TD, Stacy, GS.  MRI of Cystic and Soft Tissue Masses of the Shoulder Joint. American Journal of Roentgenology, July 2004.

Stacy GS, O’Connor EE. Osteoblastoma Imaging. Medscape. Updated Febuary 5, 2016. Available at:

Awards and Affiliations

Academic Achievement Award in Geriatrics, SUNY Upstate Medical Center, 2005

Attending of the Year 2008-09, Department of Radiology

Russell and Pearl Moses Memorial Endowed Medical Award for Outstanding Teaching for Temple University School of Medicine, 2012 – 2013

Golden Apple Award - Awarded by the Temple University Chapter of the American Medical Student Association to members of the faculty in recognition of outstanding dedication, ability and zeal in furthering the education of medical students, 2012 - 2013

Herbert M. Stauffer Award for Best Education Paper published in Academic Radiology, 2017

Grants and Contracts

7/1/16 – 6/30/17, Principal Investigator

Brain Structure and Functional Connectivity in HIV Infection

Bridge Program Award from the Office of the Vice President for Research Administration (OVPR) at Temple University


5/1/13 - 8/30/14, Principal Investigator

The relationship between resting state functional connectivity and neurocognitive function in HIV infected subjects: a pre and post cART perspective

Developmental grant from the NIMH supported Comprehensive NeuroAIDS Center


7/1/13 – 12/31/15, Principal Investigator

The effects of implementation of flipped classroom instruction in radiology on students’ task value, achievement emotions and  academic success: a comparison of flipped-classroom pedagogy to traditional didactic instruction