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Adina Maniu, MD

Academic Title:

Assistant Professor

Primary Appointment:

Obstetrics, Gynecology and Reproductive Sciences

Additional Title:

Assistant Professor

Location:

Paca/Redwood

Phone (Primary):

667-214-1300

Fax:

410-328-2648

Education and Training

  • National College Mircea cel Batrin, Constanta, Romania, BS, 1992
  • Ovidus University, Constanta, Romania, M.D., 1998
  • University of Maryland School of Medicine, PhD, 2005
  • Eastern Virginia Medical School, Norfolk, VA, Residency, 2009

Biosketch

I have been closely involved in the study of fetal adrenal development and insulin sensitivity in the baboon offspring, as performed at University of Maryland School of Medicine and Eastern Virginia Medical School. During this time, I conducted experiments and developed new research protocols which showed that estrogen regulates fetal adrenal gland development and the onset of insulin sensitivity in offspring after birt. The current grant application is a logical continuation of our study of fetal programming of insulin sensitivity after birth with a particular interest in the effect of estrogen on vascularization of skeletal muscle.

Having a background as a physician in the field of Obstetrics and Gynecology, I have the expertise in clinical application and translation of the results expected on insulin sensitivity in the nonhuman primate model to the humans.

Research/Clinical Keywords

General Women's Medical care

Highlighted Publications

Maniu A, Aberdeen GW, Lynch TJ, Nadler J, Kim SO, Quon M, Pepe GJ, Albrecht ED, Estrogen deprivation in primate pregnancy leads to insulin  resistance in offspring J Endocrinol. (2016) May 20. pii: JOE-15-0530

 

Pepe GJ, Maniu A, Aberdeen G, Lynch TJ, Albrecht ED, Estrogen Regulation of Fetal Adrenal Cortical Zone-Specific Development in the Nonhuman Primate ImpactsAdrenal Production of Androgen and Cortisol and Response to ACTH in Females in Adulthood. Endocrinology. (2016) May; 157(5): 1905-13. doi:10.1210/en.2015-2087

 

 

Research Interests

My prior research focused on the role of estrogen on fetal adrenal gland development and adrenocortical function after birth in the neonates and adult baboons. In the recent studies we have investigated the physiologic impact of placental estrogen, directly or indirectly via development of fetal adrenal gland function in programming mechanisms that lead to insulin sensitivity after birth.