Education and Training
BA - Zoology; Miami University - 2009
MA - Biology; Kent State University - 2012
Ph.D - Cellular and Molecular Biology; Cleveland Clinic/Kent State Collaborative Doctoral Program - 2015
Postdoctoral Fellowship - Molecular Neuroscience; Lewis Katz School of Medicine at Temple University - 2017
Dr. Iffland is a Research Associate in the Department of Neurology at the University of Maryland School of Medicine conducting research in the lab of Dr. Peter B. Crino, MD, Ph.D. His research involves using in vivo and in vitro methods to functionally validate and define the physiological consequence of mutations associated with cortical malformations and epilepsy. Dr. Iffland is particularly interested in mutations in the amino acid regulatory arm of the mTOR pathway (e.g., DEPDC5 and NPRL3) and how they affect neuronal morphology, function, gene transcription and brain development.
Cortical malformations, epilepsy, GATORopathies, hemimegalencephaly, focal cortical dysplasia, PMSE
Iffland PH 2nd, Crino PB. Focal Cortical Dysplasia: Gene mutations, Cell Signaling and Therapeutic Implications. Annual Reviews of Pathology: Mechanisms of Disease. 2017; 12:547-71.
Iffland PH 2nd, Crino PB. Sending mixed signals: The expanding role of molecular cascade mutations in malformations of cortical development and epilepsy. Epilepsy Currents. 2016 May.
Janigro, D, Iffland, PH 2nd, Marchi, N, Granata T. A role for inflammation in status epilepticus is revealed by a review of current therapeutic approaches. Epilepsia. 2013 Sep; 54 Suppl 6: 30-2.
Iffland, PH 2nd, Carvalho-Tavares J, Trigunaite, A, Man, S, Rasmussen, P, Alexopoulos, A, Ghosh, C, Jorgensen TN, Janigro, D. Intracellular and circulating neuronal antinuclear antibodies in human epilepsy. Neurobiol of Dis. 2013 November.
2015 Tier IV Caregiver Award, Cleveland Clinic
2014 Fellows Program, American Epilepsy Society
2014 Tier I Caregiver Appreciation Award, Cleveland Clinic
2014 Alumni, San Servolo Advanced International Course in Epilepsy, Venice Intl. University
- Course Title: Bridging basic and clinical epileptology
- Mentors: Peter Engel, MD, Ph.D and Matthew Walker, MD
2014 International Travel Award, Kent State University
2013 Domestic Travel Award, Kent State University
2013 Honorable Mention, National Center of Regenerative Medicine
2008 College of Arts and Sciences Deans Scholar, Miami University
2008 Doctoral/Undergraduate Opportunities for Scholarship Award, Miami University
2007 Undergraduate Summer Scholars Award, Miami University