Academic Title:
Assistant Professor
Primary Appointment:
Anesthesiology
Location:
UMMC, S8D
Phone (Primary):
(410) 328-3961
Phone (Secondary):
(410) 328-9813
Fax:
(410) 328-5531
Education and Training
Education
2005-2009: B.S., Biology, summa cum laude, Howard University, Baltimore, MD
2011-2012: M.D., University of Maryland School of Medicine, Baltimore, MD
Post Graduate Education and Training
2013-2017: Residency, Anesthesiology (Categorical with preliminary year in Internal Medicine), University of Maryland Medical Center, Baltimore, MD
2017-Present: Fellowship, Cardiothoracic Anesthesiology, University of Maryland Medical Center, Baltimore, MD
Biosketch
Dr. Henderson is a native of the Maryland/DC suburbs, he graduated from Howard University and completed medical school training at the University of Maryland School of Medicine. He completed his residency in anesthesiology at University of Maryland Medical Center, where he served as the Chief Resident in 2016-2017. He stayed on with the Department and completed his fellowship in Cardiothoracic Anesthesiology in 2017-2018. He will be joining the Cardiac Division, working primarily at UMMC.
Highlighted Publications
- Hecker PA, Galvao TF, O'Shea KM, Brown BH, Henderson R, Riggle H, Gupte SA, Stanley WC. High-sugar intake does not exacerbate metabolic abnormalities or cardiac dysfunction in genetic cardiomyopathy. Nutrition. 2012;28(5):520-6. PMID: 22304857.
- Henderson R, Chow R, Morales R, Taylor B, Mazzeffi MA. Removal of an Entrapped Lumbar Drain After Thoracic Endovascular Aortic Repair. A A Case Rep. 2016;7(4):93-5. PMID: 27525494.
- Henderson RS, Deshpande S, Williams B, Taylor BS, Tanaka KA. Idarucizumab for Dabigatran Reversal in Emergency Type-A Aortic Dissection. J Cardiothor Vasc Anesth. 2017;31(6):e80-e81. PMID: 27498256.
- Henderson R, Chow JH, Tanaka KA. A Bridge to Bloodless Surgery: Use of Hemoglobin-Based Oxygen Carrier for Anemia Treatment and Autologous Blood Preservation During Redo Pulmonic Valve Replacement. J Cardiothorac Vasc Anesth. 2018;33(7):1973-1976. PMID: 30529178.
- Hasan S, Abuelkasem E, Williams B, Henderson R, Mazzeffi MA, Tanaka KA. Factor IX from prothrombin complex concentrate augments low-dose tissue factor-triggered thrombin generation in vitro. Br J Anaesth. 2018;121(4):936-943. PMID: 30236256.
- Henderson RA, Mazzeffi MA, Tanaka KA. Fibrinogen Concentrate: Is It Standard Currency or Bitcoin in Bleeding Management? Anesth Analg. 2018;127(3):603-604. PMID: 30113977.
- Chow JH, Galvagno SM, Tanaka KA, Mazzeffi MA, Chancer Z, Henderson R, McCurdy MT. When All Else Fails: Novel Use of Angiotensin II for Vasodilatory Shock: A Case Report. A A Pract. 2018;11(7):175-180. PMID: 29688923.
- Abuelkasem E, Mazzeffi MA, Henderson RA, Wipfli C, Monroe A, Strauss ER, Chow JH, Tanaka KA. Clinical impact of protamine titration-based heparin neutralization in patients undergoing coronary bypass grafting surgery. J Cardiothorac Vasc Anesth. 2019;33(8):2153-2160. PMID: 30737123.
- Tanaka KA, Bharadwaj S, Hasan S, Judd M, Abuelkasem E, Henderson RA, Chow JH, Williams B, Mazzeffi MA, Crimmins SD, Malinow AM. Elevated fibrinogen, von Willebrand factor, and Factor VIII confer resistance to dilutional coagulopathy and activated protein C in normal pregnant women. Br J Anaesth. 2019;122(6):751-759. PMID: 30916034.
- Tanaka KA, Henderson R, Williams B. Heparin-Induced Thrombocytopenia and Cardiac Surgery: Can We Do It All With Cangrelor? A A Pract. 2019;13(9):366. PMID: 31567127.
- Henderson RA, Mazzeffi MA, Strauss ER, Williams B, Wipfli C, Dawood M, Taylor BS, Tanaka KA. Impact of intraoperative high-volume autologous blood collection on allogeneic transfusion during and after cardiac surgery: a propensity score-matched analysis. Transfusion. 2019;59(6):2023-2029. PMID: 30882929.
- Anders M, Rock P, Cartron A, Chow J, Henderson R, Martz D, Tanaka K, Mazzeffi M. Isolated Platelet Concentrate Transfusion During Surgery: A Single-Center Observational Cohort Study. Transfusion. 2019;59(5):1661-1666. PMID: 30693940.
- Tanaka KA, Henderson RA, Strauss ER. Evolution of Viscoelastic Coagulation Testing. Expert Rev Hematol. 2020;13(7):697-707. PMID: 32310702.
- Williams B, Henderson R, Reformato VS, Pham T, Taylor BS, Tanaka KA. Hemostasis Management of Patients Undergoing Emergency Cardiac Surgery After Ticagrelor Loading. J Cardiothorac Vasc Anesth. 2020;34(1):168-174. PMID: 31375405.
- Henderson RA, Choi S. History and Practice of Acute Normovolemic Hemodilution. Curr Anesthesiol Rep. 2020;10, 282-288.
- Chow JH, Abuelkasem E, Sankova S, Henderson RA, Mazzeffi MA, Tanaka KA. Reversal of Vasodilatory Shock: Current Perspectives on Conventional, Rescue, and Emerging Vasoactive Agents for the Treatment of Shock. Anesth Analg. 2020;130(1):15-30. PMID: 31348056.
- Madathil R, Tabatabai A, Rabin J, Menne A, Henderson R, Mazzeffi M, Scalea T, Tanaka K. Thromboelastometry and D-dimer elevation in Coronavirus-2019. J Cardiothorac Vasc Anesth. 2020;34(12):3495-3496. PMID: 32593588.
- Henderson RA, Judd M, Strauss ER, Gammie JS, Mazzeffi MA, Taylor BS, Tanaka KA. Hematologic evaluation of intraoperative autologous blood collection and allogeneic transfusion in cardiac surgery. Transfusion. 2021;61(3):788-798. PMID: 33423288.
- Pasrija C, Quinn RW, Bernstein D, Tran D, Alkhatib H, Rice M, Morales D, Shah A, Ghoreishi M, Strauss ER, Henderson R, D'Ambra MN, Gammie JS. Mitral Valve Translocation: A Novel Operation for the Treatment of Secondary Mitral Regurgitation. Ann Thorac Surg. 2021;112(6):1954-1961. PMID: 34419436.
- Patel PA, Henderson RA, Bolliger D, Erdoes G, Mazzeffi MA. The Year in Coagulation: Selected Highlights from 2020. J Cardiothorac Vasc Anesth. 2021:35(8):2260-2272. PMID: 33781668.
- Mazzeffi M, Judd M, Rabin J, Tabatabai A, Menaker J, Menne A, Chow J, Shah A, Henderson R, Herr D, Tanaka K. Tissue Factor Pathway Inhibitor Levels During Veno-Arterial Extracorporeal Membrane Oxygenation in Adults. ASAIO J. 2021;67(8):878-883. PMID: 33606392.
- Strauss ER, Li S, Henderson R, Carpenter R, Guo D, Thangaraju K, Katneni U, Buehler PW, Gobburu JV, Tanaka KA. A Pharmacokinetic and Plasmin-Generation Pharmacodynamic Assessment of a Tranexamic Acid Regimen Designed for Cardiac Surgery With Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 2022;36(8 Pt A):2473-2482. PMID: 35094925.
- Fabbro M, Patel PA, Henderson RA, Bolliger D, Tanaka KA, Mazzeffi MA. Coagulation and Transfusion Updates From 2021. J Cardiothorac Vasc Anesth. 2022;36(9):3447-3458. PMID: 35750604.
- Mazzeffi M, Henderson R, Krause E, Rabin J, Madathil R, Chow J, Grazioli A, Meyer M, Wu Z, Tanaka K. In Vitro Comparison of Recombinant and Plasma-Derived von Willebrand Factor Concentrate for Treatment of Acquired von Willebrand Syndrome in Adult Extracorporeal Membrane Oxygenation Patients. Anesth Analg. 2022;134(2):312-321. PMID: 34903705.
- Tanaka KA, Henderson R, Thangaraju K, Morita Y, Mazzeffi MA, Strauss E, Katneni U, Buehler PW. In vitro effects of emicizumab on activated clotting time in blood samples from cardiac surgical patients. Haemophilia. 2022;28(1):183-190. PMID: 34735039.
- Strauss ER, Quinn RW, Pasrija C, Henderson R, Holmes SD, D'Ambra MN, Gammie JS. Intraoperative echocardiographic assessment of mitral valve translocation. Eur J Cardiothorac Surg. 2022;62(2):ezac133. PMID: 35277715.
- Denault A, Couture EJ, De Medicis E, Shim J, Mazzeffi M, Henderson RA, Langevin S, Dhawan R, Michaud M, Guensch DP, Berger D, Erb JM, Gebhard CE, Royse X, Levy D, Lamarche Y, Dagenais F, Deschamps A, Desjardins G, Beaubien-Souligny W. Perioperative Doppler ultrasound assessment of portal vein flow pulsatility in high-risk cardiac surgery patients: a multicentre prospective cohort study. Br J Anaesth. 2022;129(5):659-669. PMID: 36184294.
- Fontaine MJ, Lasola JJ, Henderson RA. Perioperative Platelet Transfusion: Not All Platelet Products Are Created Equal. Curr Anesthesiol Rep. 2022;12(1): DOI: 10.1007/s40140-022-00522-4.
- Choi S, Mazzeffi MA, Henderson R, Mondal S, Morita Y, Deshpande S, Tanaka K. The FIBTEM paradox: Do coronary artery bypass grafting patients with high baseline FIBTEM clot firmness need more allogeneic blood transfusion? Transfusion. 2022;62(10):2020-2028. PMID: 36053950.
- Mazzeffi M, Henderson R, Powell E, Strauss E, Williams B, Tanaka K, Yang S, Deatrick K, Madathil R. Thrombopoietin, Soluble CD40 Ligand, and Platelet Count During Veno-arterial Extracorporeal Membrane Oxygenation. ASAIO J. 2022;68(5):e77-e79. PMID: 34081052.
- Guinn N, Tanaka K, Erdoes G, Kwak J, Henderson R, Mazzeffi M, Fabbro M, Raphael J. The Year in Coagulation and Transfusion: Selected Highlights from 2022. J Cardiothor Vasc Anesth. 2023;https://doi.org/10.1053/j.jvca.2023.08.132.
Additional Publication Citations
Research Interests
Research Interest:
- Blood product utilization
- Coagulation profiles of cardiac surgery patients
- Effect of blood products on endothelial function
- Alternative blood product utilization
- Left ventricular and right ventricular strain assessment
- Cardiac surgery-induced acute kidney injury
Research Activities:
- Blood Conservation Techniques in Cardiac Surgery
- Benefits of Autologous Blood in Cardiac Surgical Patients
- Novel Platelet Substitutions and Advancements
- Novel Hemodynamic Monitors in Cardiac Surgery
- Hemolysis on Cardiopulmonary Bypass
- Viscoelastic Coagulation Monitors and Point of Care Assessment of Coagulopathy in Cardiac Surgical Patients
- Hemoglobin Oxygen Based Carrier Benefits and Pitfalls
Clinical Specialty Details
- Cardiothoracic Anesthesiology
- Transesophageal Echocardiography
Awards and Affiliations
2009 | Scholarship, UMSOM |
2016 | Chief Resident, UMMC, Department of Anesthesiology |
Grants and Contracts
2017 |
PI,2%; PI – Reney Henderson Optimized administration of Prothrombin complex concentrate (PCC) vs Standard Transfusion during/after Heart Transplantation (OPSTAHT) CSL Behring Award Total: $309,685.80 |
2017 |
PI,2%; PI - Reney Henderson Reduction of Free Hemoglobin during Cardiac Surgery (REFRESH II) Cytosorb Award Total: $110,661.13 |
2020 |
PI,2%; PI - Reney Henderson ROTEM sigma External Matrix Comparison Study: Venous versus Arterial Citrated Whole Blood Samples Award Total: $30,754.10 |
2020 |
PI,2%; PI - Reney Henderson ROTEM Sigma External Method Comparison Instrumentation Laboratory Company Award Total: $42,628.30 |
8/1/2021 |
PI,2%; PI - Reney Henderson ECOM vs TDCO and FLOTRAC Clinical Accuracy Study Award Total: $69,915.40 |
2/26/2023-present |
PI, 1% CRYPTICS- Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery United States Military Award Total: $384,284.00 |
Completed Grants |
|
2018-2018 |
SCA Fellow Travel Grant Society of Cardiovascular Anesthesiologists Award Total: $1,000.00 |
2019-2021 |
PI,2%; PI - Reney Henderson Emicizumab: A Pilot in Vitro Experiment Award Total: $60,546.34 |
Community Service
Local | |
---|---|
2005-2007 | Participant, DC Helping the Homeless Walk |
2008-2009 | Physician's Aid, Howard University Hospital |
2009-2012 |
Translator, Catholic Charities, Washington, DC English to Spanish Translator at Free Healthcare Clinic |
2009-2012 | Healthcare for the Homeless, University of Maryland, Baltimore, Free Healthcare Clinic |
National | |
2021-present | Participant, Susan G. Komen 5K Walk |
2022-present | Participant, March of Dimes Walk |
Professional Activity
2019-present |
Member, Clinical Competency Committee, Anesthesiology, University of Maryland School of Medicine |
2021-present |
Resident Cardiothoracic Anesthesia Rotation Director, University of Maryland School of Medicine |
2021-present |
Director, Anesthesiology Resident Transesophageal Echocardiography Rotation, Department of Anesthesiology, University of Maryland School of Medicine |
2021-present |
Member, IDEA (Inclusion, Diversity, Equity and Antiracism) Taskforce, Department of Anesthesiology, University of Maryland School of Medicine |
2023-present |
Associate Program Director, Department of Anesthesiology, University of Maryland School of Medicine, Cardiothoracic Anesthesiology Fellowship Program |
Institutional - UMSOM | |
2020-present | Member, Admissions Committee, UMSOM |
2020-present | Member, Diversity Advisory Committee, UMSOM |
2022-present | Member, LCME Subcommittee, UMSOM |
Institutional - UMB | |
2020-present | Member, Faculty Senate, University of Maryland Baltimore |
National Service | |
2020-present |
Member, Blood Conservation Working Group, Society of Cardiovascular Anesthesiologists |
2022-present |
Member, Blood Conservation Committee, American Society of Anesthesiologists |
2022-present |
Member, American Society of Anesthesiologists, Cardiovascular and Thoracic Education Committee |
2022-present |
Member, American Society of Anesthesiologists, Cardiovascular and Thoracic Committee |
2023-present | Member, Acute Kidney Injury Working Group Sub-committee, Society of Cardiovascular Anesthesiologists |
2023-present | Editor, Frontier Anesthesiology Journal |