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Michelle G. Giglio, PhD

Academic Title:

Associate Professor

Primary Appointment:


Administrative Title:

Associate Director, Analysis

Additional Title:

Academic and Outreach Coordinator, Institute for Genome Sciences; Associate Director for Analysis, Informatics Resource Center, Institute for Genome Sciences


Health Sciences Facility III, 670 West Baltimore St, Baltimore 21201

Phone (Primary):

(410) 706-7694

Education and Training

B.S. University of Maryland College Park, 1990

Ph.D. Johns Hopkings University School of Medicine, 1997

Postdoc The Insititue for Genomic Research, Rockville, MD 1997-1998


Staff Scientist, The Institute for Genomic Research, 1998-2007

Assistant Professor, University of Maryland School of Medicine, Department of Medicine and Institute for Genome Sciences, 2007-2015

Associate Professor, University of Maryland School of Medicine, Department of Medicine and Institute for Genome Sciences, 2015-Present

Research/Clinical Keywords

genomics, transcriptomics, metagenomics, microbiome, annotation, ontology, training, outreach, K-12 outreach

Highlighted Publications

Lloyd-Price J, Mahurkar A, Rahnavard G, Crabtree J, Orvis J, Hall AB, Brady A,Creasy HH, McCracken C, Giglio MG, McDonald D, Franzosa EA, Knight R, White O,Huttenhower C. Strains, functions and dynamics in the expanded Human Microbiome Project. Nature. 2017 Oct 5;550(7674):61-66.


Giglio M, Tauber R, Nadendla S, Munro J, Olley D, Ball S, Mitraka E, Schriml LM, Gaudet P, Hobbs ET, Erill I, Siegele DA, Hu JC, Mungall C, Chibucos MC. ECO, the Evidence & Conclusion Ontology: community standard for evidence information. Nucleic Acids Res. 2019 Jan 8;47(D1):D1186-D1194. doi: 10.1093/nar/gky1036.

The Gene Ontology Consortium. The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Res. 2019 Jan 8;47(D1):D330-D338. doi: 10.1093/nar/gky1055.


Deborah A. Siegele, Sandra A. LaBonte, Peter I-Fan Wu, Marcus C. Chibucos, Suvarna Nandendla, Michelle G. Giglio & James C. Hu. Phenotype annotation with the ontology of microbial phenotypes (OMP). Journal of Biomedical Semantics, volume 10, Article number: 13 (2019)




Research Interests

Data Coordination and Standardization:

Ontology Development: I am the PI of the Evidence Ontology. I am a co-investigator on the Ontology for Microbial Phenotypes. I have been part of the Gene Ontology Consortium for nearly 20 yars working in areas of term developoment related to prokaryotic biology.

Prokaryotic sequence analysis:  I'm the PI for the Analysis Engine project, previously funded by the NIGMS to provide  analysis services for prokaryotic sequences. Services include single genome annotation, comparative genomics, and transcriptomics. Analysis tools are made available in a variety of ways to allow users to choose the approach most suited to them. Under this project we continue to develop the pipelines and tools to further meet users needs.

Outreach: I organize and run several STEM events to K-12 schools/programs each year. These are focused primarily at middle and high school students with a particular focus on the west Baltimore community.

Training: I run a professional development workshop program that includes multiple different workshops focused on aspects of bioinformatics including genomics, transcriptomics, metagenomics, comparative genomics, and programming.


Awards and Affiliations

I was named one of Maryland's Top 100 Women by the Daily Record in 2014

I received the Founders Week Public Servant of the Year award, UMB 2019

Community Service

I am involved in multiple outreach events to local K-12 students including the CURE Scholars program and the Maryland Microbiome Project.