Nathan P. Cramer, PhD

University of Maryland College Park, BS, Physics, 2001

University of Maryland School of Medicine, Neuoscience, 2007

Cornell University, Postdoctoral Study, 2009

Uniformed Services University of the Health Sciences, Postdoctoral Study, 2013

Nathan Cramer, Ph.D., joined the Department of Anatomy and Neurobiology as an Assistant Professor in February 2019. He is a UMB alumnus who received his doctorate in Neuroscience from the Graduate Program in Life Sciences in 2007. He comes from the Uniformed Services University of the Health Sciences where his research focused on how the central nervous system adapts to prolonged high altitude exposure and the role of microglia in mediating inflammatory responses. His current research as a member of the Keller lab examines how changes in brain nuclei involved in pain processing are altered during chronic pain and long-term opioid use. In particular, he is interested in understanding how chronic opioid use leads to hyperalgesia and the mechanisms which facilitate pain perception during withdrawal. 

nociception, pain perception

• Cramer NP, Korotcov A, Bosomtwi A, Xu X, Holman DR, Jones S, Hoy A, Dardzinski BJ, Galdzicki Z Neuronal and vascular deficits following chronic adaptation to high altitude. Experimental Neurology (2018) Oct 13; 311:293-304
• Marion CM, Radomski KL, Cramer NP, Galdzicki Z, Armstrong RC. Experimental traumatic brain injury identifies distinct early and late phase axonal conduction deficits of white matter pathophysiology, and reveals intervening recovery. J. Neurosci (2018) Oct 10;38(41):8723-8736
• Logue, OC, Cramer NP, Xu X, Perl, DP, & Galdzicki Z. Alterations of functional properties of hippocampal networks following repetitive closed-head injury. Exp Neurol (2016) 277, 227-243. 
• Olmos-Serrano JL, Kang, HJ, Tyler WA, Silbereis JC, Cheng F, Zhu, Y, Pletikos, M, Jankovic-Rapan L, Cramer NP, Galdzicki Z, Goodliffe J, Peters A, Sethares C, Delalle I, Golden JA, Haydar TF & Sestan N. Down syndrome developmental brain transcriptome reveals defective oligodendrocyte differentiation and myelination. Neuron (2016) 89, 1208-1222.
• Cramer NP, Xu X, Christensen C, Bierman A, Tankersley C, Galdzicki Z. Strain variation in the adaptation of C57Bl6 and BALBc mice to chronic hypobaric hypoxia Physiology and Behavior (2015) May 1;143:158-65
• Cramer NP, Chatterjee M, Lischka F, Juliano SJ. Culturing layer specific neocortical neurons as a cell replacement therapy following traumatic brain injury Frontiers in Neurology 2014 Jan 7;4:21