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Soren M. Bentzen, PhD, DMSc

Academic Title:


Primary Appointment:

Epidemiology & Public Health

Secondary Appointment(s):

Radiation Oncology

Administrative Title:

Division Director, Biostatistics And Bioinformatics

Additional Title:

Director of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center Biostatistics Shared Service, Director of the Biostatistics Core of the Institute of Clinical and Translational Research (ICTR)


HH 109D

Phone (Primary):




Education and Training

D.M.Sc. (Doctor of Medical Science), Medicine/Clinical Radiobiology, U of Aarhus, Denmark, 1994

Ph.D. in Medicine/Medical Physics, University of Aarhus, Denmark, 1986

M.Sc. in Physics, University of Aarhus, Denmark, 1981

B.Sc. in Physics & Mathematics, University of Aarhus, Denmark, 1978.


Søren M. Bentzen, MSc, PhD, DMSc, Professor, Director of the Division of Biostatistics and Bioinformatics, Department of Epidemiology and Public Health, University of Maryland School of Medicine since 2013. Dr. Bentzen also serves as Director of the Biostatistics Shared Service, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, and as Director of the Biostatistics Core of the University of Maryland Baltimore Institute of Clinical and Translational Research (ICTR). He is also an Adjunct Professor of Radiobiology and Medical Physics, University of Copenhagen, Denmark. His previous appointments include MD Anderson Cancer Center (1987-1988), Danish Cancer Society/Aarhus University (1988-1997), Gray Laboratory/Mount Vernon Hospital, London (1998-2004), and University of Wisconsin School of Medicine and Public Health (2005-2013) where he was a professor of Human Oncology and held affiliate faculty positions in the departments of Biostatistics & Medical Informatics and in Medical Physics.

Dr. Bentzen received a MSc in physics and mathematics (1981), a PhD in medical image analysis (1986), and a DMSc (doctor of medical science) in quantitative clinical radiobiology (1994), all from Aarhus University, Denmark. He has published >500 original papers and book chapters, and has presented >370 invited lectures. He currently serves on 10 international cancer journal editorial boards. His research has been recognized by 30 awards and honors, including the ASTRO Gold Medal (2017), ESTRO Breuer Gold Medal (2003), the MD Anderson Distinguished Alumnus Award (2008), and Honorary Life Memberships of the Association of Radiation Oncologists of India (2008), the Belgian Society for Therapeutic Radiology and Oncology (2009), and the German Society for Radiation Oncology (2020). He was inducted as a Fellow of the American Society of Radiation Oncology (FASTRO) in 2018. He held an Honorary Professorship at University College London (2000-2005) and was a Visiting Statistician to the Medical Research Council Clinical Trials Office, London, UK (1998-2004).

Dr. Bentzen is currently the principal investigator of a randomized controlled phase III trial of resource sparing radiation therapy for locally-advanced squamous cell carcinoma of the head and neck, sponsored by the International Atomic Energy Agency; member of the Head and Neck Cancer Steering Committee of the National Cancer Institute (NCI); founding member of the Steering Committee of the International Radiogenomics Consortium; member of the UICC Global Task Force on Radiotherapy for Cancer Control; member of the Board of Directors of the International Commission on Radiation Units. Dr. Bentzen was one of the leaders of the QUANTEC (Quantitative Analyses of Normal Tissue Effects in the Clinic) initiative (2007-2010) and serves as a member of the PENTEC (Pediatric Normal Tissue Effects in the Clinic) steering committee (2016-present). He was a member of the ASTRO Task Forces to develop evidence-based guidelines on the appropriate fractionation for whole breast irradiation (2009-2010) and for localized prostate cancer (2016-2018). He has served as chair or member of 17 (seven currently active) Independent Data and Safety Monitoring Committees or Trial Steering Committees. Served as co-chair for Translational Research for two RTOG phase III trials.

His main research interests include bioeffect modeling; biomathematics; applied biostatistics; clinical trial design; evidence-based medicine; late effects of radiotherapy; clinical radiobiology; integration of data from genomics, proteomics, and molecular imaging into novel therapeutic strategies.

In addition to his role as Director of the Biostatistics Shared Service, Dr. Bentzen is a member of the Experimental Therapeutics Program within the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center Program in Oncology. He collaborates with both basic and clinical researchers, aiming for the rapid translation of discoveries from the laboratory to the clinic. Dr. Bentzen’s research focuses on three broad fields: normal-tissue radiation biology; biomarkers, including genomic and imaging biomarkers, in predictive oncology; and the pre-clinical and clinical development of drug-radiation combinations.

Additional Publication Citations

For my up-to-date full PubMed bibliography click here.

Buffa FM, Bentzen SM, Daley FM, Dische S, Saunders MI, Richman PI, Wilson GD. 2004. Molecular marker profiles predict locoregional control of head and neck squamous cell carcinoma in a randomized trial of continuous hyperfractionated accelerated radiotherapy. Clin Cancer Res 10:3745-3754.

Trotti A, Bentzen SM. 2004. The need for adverse effects reporting standards in oncology clinical trials. J Clin Oncol 22:19-22.

Bentzen SM. 2005. Theragnostic imaging for radiation oncology: dose-painting by numbers. Lancet Oncol 6:112-117.

Bentzen SM, Atasoy BM, Daley FM, Dische S, Richman PI, Saunders MI, Trott KR, Wilson GD. 2005. Epidermal growth factor receptor expression in pretreatment biopsies from head and neck squamous cell carcinoma as a predictive factor for a benefit from accelerated radiation therapy in a randomized controlled trial. J Clin Oncol 23:5560-5567.

Bentzen SM, Heeren G, Cottier B, Slotman B, Glimelius B, Lievens Y, van den Bogaert W. 2005. Towards evidence-based guidelines for radiotherapy infrastructure and staffing needs in Europe: the ESTRO QUARTS project. Radiother Oncol 75:355-365.

Nordsmark M, Bentzen SM, Rudat V, Brizel D, Lartigau E, Stadler P, Becker A, Adam M, Molls M, Dunst J, Terris DJ, Overgaard J. 2005. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study.Radiother Oncol 77:18-24.

Bentzen SM. 2006. Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology. Nat Rev Cancer 6:702-713.

Koukourakis MI, Bentzen SM, Giatromanolaki A, Wilson GD, Daley FM, Saunders MI, Dische S, Sivridis E, Harris AL. 2006. Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial. J Clin Oncol 24:727-735.

Owen JR, Ashton A, Bliss JM, Homewood J, Harper C, Hanson J, Haviland J, Bentzen SM, Yarnold JR. 2006. Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: long-term results of a randomised trial. Lancet Oncol 7:467-471.

Rustin GJ, Timmers P, Nelstrop A, Shreeves G, Bentzen SM, Baron B, Piccart MJ, Bertelsen K, Stuart G, Cassidy J, Eisenhauer E. 2006. Comparison of CA-125 and standard definitions of progression of ovarian cancer in the intergroup trial of cisplatin and paclitaxel versus cisplatin and cyclophosphamide. J Clin Oncol 24:45-51.

Bentzen SM, Harari PM, Bernier J. 2007. Exploitable mechanisms for combining drugs with radiation: concepts, achievements and future directions. Nat Clin Pract Oncol 4:172-180.

Bentzen SM, Trotti A. 2007. Evaluation of early and late toxicities in chemoradiation trials. J Clin Oncol 25:4096-4103.

Li J, Bentzen SM, Renschler M, Mehta MP. 2007. Regression after whole-brain radiation therapy for brain metastases correlates with survival and improved neurocognitive function. J Clin Oncol 25:1260-1266.

Short SC, Buffa FM, Bourne S, Koritzinsky M, Wouters BG, Bentzen SM. 2007. Dose- and time-dependent changes in gene expression in human glioma cells after low radiation doses. Radiat Res 168:199-208.

Tang PA, Bentzen SM, Chen EX, Siu LL. 2007. Surrogate end points for median overall survival in metastatic colorectal cancer: literature-based analysis from 39 randomized controlled trials of first-line chemotherapy. J Clin Oncol 25:4562-4568.

Bentzen SM. 2008. Radiation oncology health technology assessment: the best is the enemy of the good. Nat Clin Pract Oncol 5:563.

Bentzen SM. 2008. From cellular to high-throughput predictive assays in radiation oncology: challenges and opportunities. Semin Radiat Oncol 18:75-88.

Bentzen SM. 2008. Randomized controlled trials in health technology assessment: overkill or overdue? Radiother Oncol 86:142-147.

Bentzen SM, Agrawal RK, Aird EG, Barrett JM, Barrett-Lee PJ, Bliss JM, Brown J, Dewar JA, Dobbs HJ, Haviland JS, Hoskin PJ, Hopwood P, Lawton PA, Magee BJ, Mills J, Morgan DA, Owen JR, Simmons S, Sumo G, Sydenham MA, Venables K, Yarnold JR. 2008. The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet 371:1098-1107.

Bentzen SM, Agrawal RK, Aird EG, Barrett JM, Barrett-Lee PJ, Bliss JM, Brown J, Dewar JA, Dobbs HJ, Haviland JS, Hoskin PJ, Hopwood P, Lawton PA, Magee BJ, Mills J, Morgan DA, Owen JR, Simmons S, Sumo G, Sydenham MA, Venables K, Yarnold JR. 2008. The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet Oncol 9:331-341.

Bentzen SM, Buffa FM, Wilson GD. 2008. Multiple biomarker tissue microarrays: bioinformatics and practical approaches. Cancer Metastasis Rev 27:481-494.

Li J, Bentzen SM, Li J, Renschler M, Mehta MP. 2008. Relationship between neurocognitive function and quality of life after whole-brain radiotherapy in patients with brain metastasis. Int J Radiat Oncol Biol Phys 71:64-70.

Bernier J, Bentzen SM, Vermorken JB. 2009. Molecular therapy in head and neck oncology. Nat Rev Clin Oncol 6:266-277.

Lee AW, Ng WT, Hung WM, Choi CW, Tung R, Ling YH, Cheng PT, Yau TK, Chang AT, Leung SK, Lee MC, Bentzen SM. 2009. Major late toxicities after conformal radiotherapy for nasopharyngeal carcinoma-patient- and treatment-related risk factors. Int J Radiat Oncol Biol Phys 73:1121-1128.

Bentzen SM, Constine LS, Deasy JO, Eisbruch A, Jackson A, Marks LB, Ten Haken RK, Yorke ED. 2010. Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues. Int J Radiat Oncol Biol Phys 76:S3-9.

Bentzen SM, Parliament M, Deasy JO, Dicker A, Curran WJ, Williams JP, Rosenstein BS. 2010. Biomarkers and surrogate endpoints for normal-tissue effects of radiation therapy: the importance of dose-volume effects. Int J Radiat Oncol Biol Phys 76:S145-150.

Bentzen SM, Yarnold JR. 2010. Reports of unexpected late side effects of accelerated partial breast irradiation--radiobiological considerations. Int J Radiat Oncol Biol Phys 77:969-973.

Diez P, Vogelius IS, Bentzen SM. 2010. A new method for synthesizing radiation dose-response data from multiple trials applied to prostate cancer. Int J Radiat Oncol Biol Phys 77:1066-1071.

Haviland JS, Yarnold JR, Bentzen SM. 2010. Hypofractionated radiotherapy for breast cancer. N Engl J Med 362:1843-1844.

Hoskin PJ, Rojas AM, Bentzen SM, Saunders MI. 2010. Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma. J Clin Oncol 28:4912-4918.

Bentzen SM, Gregoire V. 2011. Molecular imaging-based dose painting: a novel paradigm for radiation therapy prescription. Semin Radiat Oncol 21:101-110.

Smith BD, Bentzen SM, Correa CR, Hahn CA, Hardenbergh PH, Ibbott GS, McCormick B, McQueen JR, Pierce LJ, Powell SN, Recht A, Taghian AG, Vicini FA, White JR, Haffty BG. 2011. Fractionation for whole breast irradiation: an American Society for Radiation Oncology (ASTRO) evidence-based guideline. Int J Radiat Oncol Biol Phys 81:59-68.

Vogelius IR, Westerly DC, Aznar MC, Cannon GM, Korreman SS, Mackie TR, Mehta MP, Bentzen SM. 2011. Estimated radiation pneumonitis risk after photon versus proton therapy alone or combined with chemotherapy for lung cancer. Acta Oncol 50:772-776.

Vogelius IS, Westerly DC, Cannon GM, Mackie TR, Mehta MP, Sugie C, Bentzen SM. 2011. Intensity-modulated radiotherapy might increase pneumonitis risk relative to three-dimensional conformal radiotherapy in patients receiving combined chemotherapy and radiotherapy: a modeling study of dose dumping. Int J Radiat Oncol Biol Phys 80:893-899.

Watkins Bruner D, James JL, Bryan CJ, Pisansky TM, Rotman M, Corbett T, Speight J, Byhardt R, Sandler H, Bentzen SM, Kachnic L, Berk L. 2011. Randomized, double-blinded, placebo-controlled crossover trial of treating erectile dysfunction with sildenafil after radiotherapy and short-term androgen deprivation therapy: results of RTOG 0215. J Sex Med 8:1228-1238.

Barnett GC, Coles CE, Elliott RM, Baynes C, Luccarini C, Conroy D, Wilkinson JS, Tyrer J, Misra V, Platte R, Gulliford SL, Sydes MR, Hall E, Bentzen SM, Dearnaley DP, Burnet NG, Pharoah PD, Dunning AM, West CM. 2012. Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study. Lancet Oncol 13:65-77.

Barnett GC, Elliott RM, Alsner J, Andreassen CN, Abdelhay O, Burnet NG, Chang-Claude J, Coles CE, Gutierrez-Enriquez S, Fuentes-Raspall MJ, Alonso-Munoz MC, Kerns S, Raabe A, Symonds RP, Seibold P, Talbot CJ, Wenz F, Wilkinson J, Yarnold J, Dunning AM, Rosenstein BS, West CM, Bentzen SM. 2012. Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity. Radiother Oncol 105:289-295.

Barnett GC, West CM, Coles CE, Pharoah PD, Talbot CJ, Elliott RM, Tanteles GA, Symonds RP, Wilkinson JS, Dunning AM, Burnet NG,Bentzen SM. 2012. Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies. Int J Radiat Oncol Biol Phys 82:1065-1074.

Bekelman JE, Deye JA, Vikram B, Bentzen SM, Bruner D, Curran WJ, Jr., Dignam J, Efstathiou JA, FitzGerald TJ, Hurkmans C, Ibbott GS, Lee JJ, Merchant TE, Michalski J, Palta JR, Simon R, Ten Haken RK, Timmerman R, Tunis S, Coleman CN, Purdy J. 2012. Redesigning radiotherapy quality assurance: opportunities to develop an efficient, evidence-based system to support clinical trials--report of the National Cancer Institute Work Group on Radiotherapy Quality Assurance. Int J Radiat Oncol Biol Phys 83:782-790.

Bentzen SM, Dorr W, Gahbauer R, Howell RW, Joiner MC, Jones B, Jones DT, van der Kogel AJ, Wambersie A, Whitmore G. 2012. Bioeffect modeling and equieffective dose concepts in radiation oncology--terminology, quantities and units. Radiother Oncol 105:266-268.

Brodin NP, Vogelius IR, Maraldo MV, Munck af Rosenschold P, Aznar MC, Kiil-Berthelsen A, Nilsson P, Bjork-Eriksson T, Specht L,Bentzen SM. 2012. Life years lost--comparing potentially fatal late complications after radiotherapy for pediatric medulloblastoma on a common scale. Cancer 118:5432-5440.

Vogelius IR, Bentzen SM. 2012. A literature-based meta-analysis of clinical risk factors for development of radiation induced pneumonitis. Acta Oncol 51:975-983.

Appelt AL, Vogelius IR, Bentzen SM. 2013. Modern hypofractionation schedules for tangential whole breast irradiation decrease the fraction size-corrected dose to the heart. Clin Oncol (R Coll Radiol) 25:147-152.

Brodin NP, Vogelius IR, Bjork-Eriksson T, Munck af Rosenschold P, Bentzen SM. 2013. Modeling freedom from progression for standard-risk medulloblastoma: a mathematical tumor control model with multiple modes of failure. Int J Radiat Oncol Biol Phys 87:422-429.

Brown PD, Pugh S, Laack NN, Wefel JS, Khuntia D, Meyers C, Choucair A, Fox S, Suh JH, Roberge D, Kavadi V, Bentzen SM, Mehta MP, Watkins-Bruner D. 2013. Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial. Neuro Oncol 15:1429-1437.

Cannon DM, Mehta MP, Adkison JB, Khuntia D, Traynor AM, Tome WA, Chappell RJ, Tolakanahalli R, Mohindra P, Bentzen SM, Cannon GM. 2013. Dose-limiting toxicity after hypofractionated dose-escalated radiotherapy in non-small-cell lung cancer. J Clin Oncol 31:4343-4348.

Hong JC, Kruser TJ, Gondi V, Mohindra P, Cannon DM, Harari PM, Bentzen SM. 2013. Risk of cerebrovascular events in elderly patients after radiation therapy versus surgery for early-stage glottic cancer. Int J Radiat Oncol Biol Phys 87:290-296.

Lawrence YR, Vikram B, Dignam JJ, Chakravarti A, Machtay M, Freidlin B, Takebe N, Curran WJ, Jr., Bentzen SM, Okunieff P, Coleman CN, Dicker AP. 2013. NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers. J Natl Cancer Inst 105:11-24.

Vogelius IR, Bentzen SM. 2013. Meta-analysis of the alpha/beta ratio for prostate cancer in the presence of an overall time factor: bad news, good news, or no news? Int J Radiat Oncol Biol Phys 85:89-94.

Vogelius IR, Hakansson K, Due AK, Aznar MC, Berthelsen AK, Kristensen CA, Rasmussen J, Specht L, Bentzen SM. 2013. Failure-probability driven dose painting. Med Phys 40: 081717.

Kerns SL, de Ruysscher D, Andreassen CN, Azria D, Barnett GC, Chang-Claude J, Davidson S, Deasy JO, Dunning AM, Ostrer H, Rosenstein BS, West CM, Bentzen SM. STROGAR - STrengthening the Reporting Of Genetic Association studies in Radiogenomics. Radiother Oncol. 2014 Jan;110(1):182-8.

Brodin NP, Vogelius IR, Björk-Eriksson T, Munck Af Rosenschöld P, Maraldo MV, Aznar MC, Specht L, Bentzen SM. Optimizing the radiation therapy dose prescription for pediatric medulloblastoma: minimizing the life years lost attributable to failure to control the disease and late complication risk. Acta Oncol. 2014 Apr;53(4):462-70.

Haviland JS, A'Hern R, Bentzen SM, Whelan T, Bliss JM. Radiotherapy for breast cancer, the TARGIT-A trial. Lancet. 2014 May 17;383(9930):1716-7.

Brink C, Bernchou U, Bertelsen A, Hansen O, Schytte T, Bentzen SM. Locoregional control of non-small cell lung cancer in relation to automated early assessment of tumor regression on cone beam computed tomography. Int J Radiat Oncol Biol Phys. 2014 Jul 15;89(4):916-23.

Rasmussen JH, Vogelius IR, Fischer BM, Friborg J, Aznar MC, Persson GF, Håkansson K, Kristensen CA, Bentzen SM, Specht L. Prognostic value of 18F-fludeoxyglucose uptake in 287 patients with head and neck squamous cell carcinoma. Head Neck. 2014 May 7. doi: 10.1002/hed.23745.

Rasmussen GB, Vogelius IR, Rasmussen JH, Schumaker L, Ioffe O, Cullen K, Fischer BM, Therkildsen MH, Specht L, Bentzen SM. Immunohistochemical biomarkers and FDG uptake on PET/CT in head and neck squamous cell carcinoma. Acta Oncol. 2015;54(9):1408-15. doi: 10.3109/0284186X.2015.1062539. Epub 2015 Aug 9. PubMed PMID: 26256482.

Nygård L, Vogelius IR, Fischer BM, Klausen TL, Langer SW, Lonsdale MN, Persson GF, Bentzen SM. Early lesion-specific (18)F-FDG PET response to chemotherapy predicts time to lesion progression in locally advanced non-small cell lung cancer. Radiother Oncol. 2016 Mar;118(3):460-4. doi:10.1016/j.radonc.2016.01.009. Epub 2016 Jan 21. PubMed PMID: 26806265.

Baumann M, Krause M, Overgaard J, Debus J, Bentzen SM, Daartz J, Richter C, Zips D, Bortfeld T. Radiation oncology in the era of precision medicine. Nat Rev Cancer. 2016 Apr;16(4):234-49. doi: 10.1038/nrc.2016.18. Epub 2016 Mar 18. Review. PubMed PMID: 27009394.

Andreassen CN, Rosenstein BS, Kerns SL, Ostrer H, De Ruysscher D, Cesaretti JA, Barnett GC, Dunning AM, Dorling L, West CML, Burnet NG, Elliott R, Coles C, Hall E, Fachal L, Vega A, Gómez-Caamaño A, Talbot CJ, Symonds RP, De Ruyck K, Thierens H, Ost P, Chang-Claude J, Seibold P, Popanda O, Overgaard M, Dearnaley D, Sydes MR, Azria D, Koch CA, Parliament M, Blackshaw M, Sia M, Fuentes-Raspall MJ, Ramon Y Cajal T, Barnadas A, Vesprini D, Gutiérrez-Enríquez S, Mollà M, Díez O, Yarnold JR, Overgaard J, Bentzen SM, Alsner J; International Radiogenomics Consortium (RgC). Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. Radiother Oncol. 2016 Dec;121(3):431-439. doi: 10.1016/j.radonc.2016.06.017. Epub 2016 Jul 18. PubMed PMID: 27443449; PubMed Central PMCID: PMC5559879.

Haviland JS, Bentzen SM, Bliss JM, Yarnold JR; START Trial Management Group. Prolongation of overall treatment time as a cause of treatment failure in early breast cancer: An analysis of the UK START (Standardisation of Breast Radiotherapy) trials of radiotherapy fractionation. Radiother Oncol. 2016 Dec;121(3):420-423. doi: 10.1016/j.radonc.2016.08.027. Epub 2016 Sep 22. PubMed PMID: 27666929.

Scilla KA, Bentzen SM, Lam VK, Mohindra P, Nichols EM, Vyfhuis MA, Bhooshan N, Feigenberg SJ, Edelman MJ, Feliciano JL. Neutrophil-Lymphocyte Ratio Is a Prognostic Marker in Patients with Locally Advanced (Stage IIIA and IIIB) Non-Small Cell Lung Cancer Treated with Combined Modality Therapy. Oncologist. 2017 Jun;22(6):737-742. doi: 10.1634/theoncologist.2016-0443. Epub 2017 May 22. PubMed PMID: 28533476; PubMed Central PMCID: PMC5469587.

Nowak RG, Ambulos NP, Schumaker LM, Mathias TJ, White RA, Troyer J, Wells D, Charurat ME, Bentzen SM, Cullen KJ. Genotyping of high-risk anal human papillomavirus (HPV): ion torrent-next generation sequencing vs. linear array.Virol J. 2017 Jun 13;14(1):112. doi: 10.1186/s12985-017-0771-z. PubMed PMID:28610586; PubMed Central PMCID: PMC5470268.

Vyfhuis MAL, Bhooshan N, Molitoris J, Bentzen SM, Feliciano J, Edelman M, Burrows WM, Nichols EM, Suntharalingam M, Donahue J, Nagib M, Carr SR, Friedberg J, Badiyan S, Simone CB 2nd, Feigenberg SJ, Mohindra P. Clinical outcomes of black vs. non-black patients with locally advanced non-small cell lung cancer. Lung Cancer. 2017 Dec;114:44-49. doi: 10.1016/j.lungcan.2017.10.016. Epub 2017
Nov 2. Erratum in: Lung Cancer. 2017 Dec 27;:. PubMed PMID: 29173764.

Ntiri SO, Klyushnenkova EN, Bentzen SM. Outcomes of a Community-based Breast Cancer Screening Program in Baltimore City. J Health Care Poor Underserved. 2018;29(3):898-913. doi: 10.1353/hpu.2018.0067. PubMed PMID: 30122671.

Vogelius IR, Bentzen SM. Dose Response and Fractionation Sensitivity of Prostate Cancer After External Beam Radiation Therapy: A Meta-analysis of Randomized Trials. Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):858-865. doi: 10.1016/j.ijrobp.2017.12.011. Epub 2017 Dec 15. PubMed PMID: 29485063.

Nygård L, Vogelius IR, Fischer BM, Kjær A, Langer SW, Aznar MC, Persson GF, Bentzen SM. A Competing Risk Model of First Failure Site after Definitive Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer. J Thorac Oncol. 2018 Apr;13(4):559-567. doi: 10.1016/j.jtho.2017.12.011. PubMed PMID: 29355615.

Nygård L, Aznar MC, Fischer BM, Persson GF, Christensen CB, Andersen FL, Josipovic M, Langer SW, Kjær A, Vogelius IR, Bentzen SM. Repeatability of FDG PET/CT metrics assessed in free breathing and deep inspiration breath hold in lung cancer patients. Am J Nucl Med Mol Imaging. 2018 Apr 25;8(2):127-136. eCollection 2018. PubMed PMID: 29755846; PubMed Central PMCID: PMC5944828.

Lühr A, von Neubeck C, Pawelke J, Seidlitz A, Peitzsch C, Bentzen SM, Bortfeld T, Debus J, Deutsch E, Langendijk JA, Loeffler JS, Mohan R, Scholz M, Sørensen BS, Weber DC, Baumann M, Krause M."Radiobiology of Proton Therapy": Results of an international expert workshop. Radiother Oncol. 2018 Jul;128(1):56-67. doi: 10.1016/j.radonc.2018.05.018. Epub 2018 Jun 1. Review. PubMed PMID: 29861141.

Pinnow E, Amr S, Bentzen SM, Brajovic S, Hungerford L, St George DM, Dal Pan G. Postmarket Safety Outcomes for New Molecular Entity (NME) Drugs Approved by the Food and Drug Administration Between 2002 and 2014. Clin Pharmacol Ther. 2018 Aug;104(2):390-400. doi: 10.1002/cpt.944. Epub 2017 Dec 20. PubMed PMID: 29266187.

Nowak RG, Bentzen SM, Ravel J, Crowell TA, Dauda W, Ma B, Liu H, Blattner WA, Baral SD, Charurat ME. Anal Microbial Patterns and Oncogenic Human Papillomavirus in a Pilot Study of Nigerian Men Who Have Sex with Men at Risk for or Living with HIV. AIDS Res Hum Retroviruses. 2018 Oct 17. doi: 10.1089/AID.2018.0158. [Epub ahead of print] PubMed PMID: 30215262.

Zandberg DP, Cullen K, Bentzen SM, Goloubeva OG. Definitive radiation with concurrent cetuximab vs. radiation with or without concurrent cytotoxic chemotherapy in older patients with squamous cell carcinoma of the head and neck: Analysis of the SEER-medicare linked database. Oral Oncol. 2018 Nov;86:132-140. doi: 10.1016/j.oraloncology.2018.09.023. Epub 2018 Sep 21. PubMed PMID: 30409293.

Modiri A, Stick LB, Rice SR, Rechner LA, Vogelius IR, Bentzen SM, Sawant A. Individualized estimates of overall survival in radiation therapy plan optimization - A concept study. Med Phys. 2018 Nov;45(11):5332-5342. doi: 10.1002/mp.13211. Epub 2018 Oct 17. PubMed PMID: 30246353.

Rice SR, Bentzen SM, Hanna A, Choi E, Boggs DH, Kwok Y, Hyder J, Feigenberg SJ, Regine WF, Woodworth GF, Eisenberg HM, Yu C, Biggins TF, Barnholtz-Sloan JS, Sperduto PW, Weltman E, Mehta MP. Prognostic models for patients with brain metastases after stereotactic radiosurgery with or without whole brain radiotherapy: a validation study. J Neurooncol. 2018 Nov;140(2):341-349. doi: 10.1007/s11060-018-2958-6. Epub 2018 Aug 21. PubMed PMID: 30132164.

Awards and Affiliations


2020 Honorary life member of the German Society for Radiation Oncology (DEGRO)

2018 Fellow of the American Society for Radiation Oncology (FASTRO)

2017 Seoul National University Hospital Distinguished Lecturer, Seoul, Republic of Korea

2017 Gold Medal, American Society for Radiation Oncology (ASTRO)

2016 Gilbert H. Fletcher Distinguished Lecturer, International Conference on Translational Research in Radiation Oncology – Physics for Health in Europe, Geneva, Switzerland

2016 Danish Association for Cancer Research Honorary Award, Copenhagen, Denmark

2015 CARO Honorary Award Lecture, Canadian Association for Radiation Oncology, Kelowna, BC, Canada

2013 International KFJ Research Award, Rigshospitalet, Copenhagen, Denmark

2011 1st James Oleson Visiting Professorship, Duke University, Durham, NC, USA

2011 Royal Australian and New Zealand College of Radiologists, Keynote Lecturer, Melbourne, VIC, Australia

2011 Douglas Lea Lecture, Institute of Physics and Engineering in Medicine, UK

2009 Honorary Life Member, Belgian Society for Therapeutic Radiology and Oncology

2009 Varian Lectureship, University of Copenhagen, Denmark

2009 Alan C Burton Lecturer, University of Western Ontario, London, ON, Canada

2009 Vaeth Lectureship, San Francisco Radiation Oncology Conference, San Francisco, CA, USA

2008 Collins Lecturer, Harvard Medical School, Boston, MA, USA

2008 Honorary Life Member, Association of Radiation Oncologists of India

2008 Dr. Solomon Padam Singh Oration, Association of Radiation Oncologists of India, Mumbai, India

2008 Distinguished Alumnus Award, University of Texas, MD Anderson Cancer Center, Houston, TX, USA

2007 Elis Berven Award Lecture, Swedish Society of Oncology

2006 Rolf Wideröe Award, Radiumhospitalet, University of Oslo, Norway 

2006 ESTRO-ICTR Translational Research Award, International Conference on Translational Research and Pre-Clinical Strategies in Radio-Oncology, Lugano, Switzerland

2003 Acta Oncologica Lectureship, Norwegian Society of Oncology

2003 Gold Medal (Klaas Breur Medal), European Society for Therapeutic Radiology and Oncology (ESTRO)

2003 Emmanuel van der Schueren Award Lecturer, European School of Oncology

2003 Institute of Cancer Research Distinguished Lecturer, Sutton, UK

2001 Allen S. Lichter Lectureship, University of Michigan, Ann Arbor, MI, USA

2001 Varian Lectureship, Harvard Medical School, Boston, MA, USA

1999 Royal Australian and New Zealand College of Radiologists Annual Lecturer, Sydney, NSW, Australia

1998 Clinical Oncology Award, Danish Society for Oncology, Denmark

1998 L.H.Gray Memorial Trust Lecture, Association for Radiation Research, UK



Professor, tenured, Department of Epidemiology and Public Health, primary faculty appointment, University of Maryland School of Medicine, Baltimore, MD, USA

Professor of Radiation Oncology, secondary faculty appointment, University of Maryland School of Medicine, Baltimore, MD, USA

Director, Division of Biostatistics and Bioinformatics, Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA

Director, University of Maryland Greenebaum Comprehensive Cancer Center Biostatistics Shared Service, University of Baltimore School of Medicine, Baltimore, MD, USA

Director, Biostatistics Core, Institute for Clinical and Translational Research, University of Maryland Baltimore, Baltimore, MD, USA

Director of Translational Research, Maryland Proton Alliance, University of Baltimore School of Medicine, Baltimore, MD, USA

Member, University of Maryland Greenebaum Comprehensive Cancer Center, Experimental Therapeutics Program, University of Baltimore School of Medicine, Baltimore, MD, USA

Member, Graduate Faculty of the University of Maryland Graduate School, Baltimore; Affiliated with the Epidemiology and Human Genetics Program and the Molecular Medicine Program

Affiliate Member, Institute for Global Health (IGH), University of Baltimore School of Medicine, Baltimore, MD, USA

Research Associate without Compensation, Department of Veterans Affairs Medical Center, Maryland Health Care System, Baltimore, MD, USA

Adjunct Professor, Department of Oncology, University of Copenhagen, Denmark

Visiting Professor, Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

Links of Interest