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Cardiovascular Research Laboratories (CVRL)

Cardiovascular disease is the leading cause of death and disability in the world, and its prevention and cure can only come from research. The graduates and faculty of the University of Maryland School of Medicine (UMSOM) have made numerous seminal contributions to cardiovascular research, including:

  • the first selective coronary angiogram
  • the racial differences in response to some blood pressure medications
  • the demonstrations of clinical effectiveness of implantable defibrillators and beta-adrenergic blockers
  • the role of calcium sparks in myocardial physiology
  • the discovery of the first null mutation in APOC3 gene conferring cardioprotection

Today, the CVRL continues this rich tradition of discovery and innovation by leveraging the unique resources of UMSOM, which include, but are not limited to the following:

CVRL brings together an interdisciplinary team of basic and clinical investigators to advance human cardiovascular biology, to train future leaders of cardiovascular research and medicine, and to transform the practice of clinical cardiology.

Our investigators are engaged in a wide range of disciplines:

  • Biochemistry & molecular biology
  • Biomedical engineering
  • Cardiology
  • Chemical biology
  • Data sciences
  • Developmental biology
  • Global health
  • Human genetics
  • Imaging sciences
  • Physiology
  • Regenerative meidicne
  • Vascular biology

CVRL Faculty and Research Interests

Translational Research

Translational research in CVRL includes basic science using animal models of disease and human translational research involving patient-derived genetic data, biomarkers and induced pluripotent stem cells (iPSCs), with the goal of gaining insight into cardiovascular disease and developing new treatment paradigms.

Clinical Research

Patient-oriented research conducted with human subjects in order to elucidate disease mechanisms, identify socioeconomic contributions to health, and evaluate new treatment paradigms at the molecular and societal levels. Clinical research can be classed as Epidemiologic Studies, Outcomes Research, and Health Services Research.

For more information, see  Faculty & Research Interests

Contact Us

Wendy L. Novak, MS
Research Administrator,
Division of Cardiovascular Medicine
110 South Paca Street, 7-N-111
Baltimore, MD 21201
Phone: 410-328-7374

Donate to the CVRL

Related Info

The Hong Laboratory

The Hong Laboratory functions at the intersection of a variety of disciplines which include zebrafish development, stem cells, drug discovery, and cardiovascular biology.

Learn more >

Data Science Initiative

The Data Science Initiative is a partnership between CVRL and colleagues in UMBC's Department of Mathematics & Statistics. This partnership allows us to use advanced Artificial Intelligence/Machine Learning as well as traditional methodologies to unravel and mine the wealth of data generated in the many critical areas.

Learn more >

News and Announcements

Follow us on Twitter: @UM_Cardiology