Cardiovascular Research Laboratories (CVRL)
Cardiovascular disease is the leading cause of death and disability in the world, and its prevention and cure can only come from research. The graduates and faculty of the University of Maryland School of Medicine (UMSOM) have made numerous seminal contributions to cardiovascular research, including the first selective coronary angiogram, the racial differences in response to some blood pressure medications, the demonstrations of clinical effectiveness of implantable defibrillators and beta-adrenergic blockers, the role of calcium sparks in myocardial physiology, and the discovery of the first null mutation in APOC3 gene conferring cardioprotection.
Today, the Cardiovascular Research Laboratories continue this rich tradition of discovery and innovation by leveraging the unique resources of UMSOM (the Amish Research Program, the Center for Biomedical Engineering and Technology, the Institute of Genomic Sciences, the Center for Biomolecular Therapeutics, the Institute for Bioscience & Biotechnology Research, the Program in Personalized and Genomic Medicine, the Institute for Clinical Translational Research, just to name a few) and bringing together an interdisciplinary team of basic and clinical investigators to advance human cardiovascular biology, to train future leaders of cardiovascular research and medicine, and to transform the practice of clinical cardiology.
Our investigators are engaged in a wide range of disciplines, including:
- Biochemistry & molecular biology
- Biomedical engineering
- Chemical biology
- Data sciences
- Developmental biology
- Global health
- Human genetics
- Imaging sciences
- Regenerative meidicne
- Vascular biology
CVRL Faculty and Research Interests
Translational research in CVRL includes basic science using animal models of disease and human translational research involving patient-derived genetic data, biomarkers and induced pluripotent stem cells (iPSCs), with the goal of gaining insight into cardiovascular disease and developing new treatment paradigms.
Patient-oriented research conducted with human subjects in order to elucidate disease mechanisms, identify socioeconomic contributions to health, and evaluate new treatment paradigms at the molecular and societal levels. Clinical research can be classed as Epidemiologic Studies, Outcomes Research, and Health Services Research.
For more information, see Faculty & Research Interests
Wendy L. Novak, MS
Division of Cardiovascular Medicine
110 South Paca Street, 7-N-111
Baltimore, MD 21201