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Amal Isaiah, MBBS, DPhil

Academic Title:

Assistant Professor

Primary Appointment:

Otorhinolaryngology-Head & Neck Surgery

Secondary Appointment(s):

Pediatrics

Additional Title:

Assistant Professor, Otorhinolaryngology--Head and Neck Surgery Pediatric Otolaryngology

Location:

16 S. Eutaw St Ste 500, Baltimore, MD 21201

Phone (Primary):

410-328-5837

Phone (Secondary):

410-328-6866

Fax:

410-328-5827

Education and Training

Medical School: St. John's Medical College, Bangalore, India (MBBS)

Graduate School: University of Oxford, England (DPhil, Neuroscience)

Internship: University of Maryland Medical Center, Baltimore, MD 

Residency: University of Maryland Medical Center, Baltimore, MD (Otorhinolaryngology)

Fellowship: University of Texas Southwestern Medical Center & Children's HealthSM, Dallas, TX (Pediatric Otolaryngology)

Board Certification: American Board of Otolaryngology

Biosketch

Dr Amal Isaiah graduated from St. John's Medical College in Bangalore, India. He was elected a Rhodes Scholar in 2006, following which he completed a DPhil (PhD) in Neurophysiology at Oxford University, England, focusing on developmental plasticity associated with cochlear implantation. Dr Isaiah then completed residency training in Otolaryngology at University of Maryland, and a clinical fellowship in Pediatric Otolaryngology at University of Texas Southwestern Medical Center/Children's Health Dallas. He is certified by the American Board of Otolaryngology.

Dr Isaiah's clinical interests span the management of upper airway obstruction in infants and children, with an emphasis on treatment of persistent pediatric sleep apnea. In addition, he has also developed technologies for precise localization of airway obstruction. His other clinical interests are surgical management of speech disorders and hearing loss in children, and has published widely in these areas. Dr Isaiah received an Early Career Award for Pediatric Research from the Gerber Foundation in 2016.

Research/Clinical Keywords

pediatric sleep apnea; airway obstruction; machine learning; biomedical devices; developmental plasticity

Highlighted Publications

Recent Peer-Reviewed Publications (2017-2018)


Wess JM*, Isaiah A*, Watkins PV, Kanold PO. Subplate neurons are the first cortical neurons to respond to sensory stimuli. Proceedings of the National Academy of Sciences. 2017 Nov 21;114(47):12602-7 (*equal contribution)

Isaiah A, Kiss E, Olomu P, Koral K, Mitchell R. Characterization of upper airway obstruction using cine MRI in children with residual obstructive sleep apnea after adenotonsillectomy. Sleep Medicine. 2017 Nov 1.

Isaiah A, Hamdan H, Johnson RF, Naqvi K, Mitchell RB. Very severe obstructive sleep apnea in children: outcomes of adenotonsillectomy and risk factors for persistence. Otolaryngology–Head and Neck Surgery. 2017 Jul;157(1):128-34.

Isaiah A, Lee D, Lenes-Voit F, Sweeney M, Kutz W, Isaacson B, Roland P, Lee KH. Clinical outcomes following cochlear implantation in children with inner ear anomalies. International journal of pediatric otorhinolaryngology. 2017 Feb 1;93:1-6.

Murphy J, Isaiah A, Dyalram D, Lubek JE. Surgical Site Infections in Patients Receiving Osteomyocutaneous Free Flaps to the Head and Neck. Does Choice of Antibiotic Prophylaxis Matter?. Journal of Oral and Maxillofacial Surgery. 2017 Oct 1;75(10):2223-9.

Ord RA, Isaiah A, Dyalram D, Lubek JE. Is Long-Term Follow-Up Mandatory for Stage I Oral Tongue Cancer?. Journal of Oral and Maxillofacial Surgery. 2018 Jul 7.

Rizzi CJ, Amin JD, Isaiah A, Valdez TA, Jeyakumar A, Smart SE, Pereira KD. Tracheostomy for Severe Pediatric Obstructive Sleep Apnea: Indications and Outcomes. Otolaryngology–Head and Neck Surgery. 2017 Aug;157(2):309-13.

Aslam-Pervez N, Caldroney SJ, Isaiah A, Lubek JE. A Retrospective Volume Matched Analysis of the Submental Artery Island Pedicled Flap as Compared to the Forearm Free Flap: Is It a Good Alternative Choice for the Reconstruction of Defects of the Oral Cavity and Oropharynx?. Journal of Oral and Maxillofacial Surgery. 2018 Mar 1;76(3):656-63.

Johnson RF, Isaiah A. Laryngeal stenosis among hospitalized children: Results from a nationwide cross‐sectional survey. Laryngoscope Investigative Otolaryngology. 2018 Mar 8.

Isaiah A, Pereira KD. Laryngotracheal anomalies and airway fluoroscopy in infants. International journal of pediatric otorhinolaryngology. 2017 Jun 1;97:109-12.

Shikara M, Rizzi CJ, Zelip B, Hubbard F, Vakharia KT, Isaiah A, Greywoode JD, Vakharia KT. Assessment of a novel computer algorithm for printing a 3-dimensional nasal prosthetic. JAMA Otolaryngology–Head & Neck Surgery. 2018 May 10.

Isaiah A, Mezrich R, Wolf J. Ultrasonographic Detection of Airway Obstruction in a Model of Obstructive Sleep Apnea. Ultrasound international open. 2017 Feb;3(1):E34.

 

Selected Book Chapters

Isaiah A, Pereira KD, Correa AG. Tracheal infections. Infectious Diseases in Pediatric Otolaryngology; Springer; 2016. pp. 163-175

Isaiah A, Pereira KD. The Effect of Body Position on Sleep Apnea in Children. Positional Therapy in Obstructive Sleep Apnea: Springer; 2015. pp. 151-61.

Isaiah A, Pereira KD. Congenital Laryngeal and Tracheal Anomalies. Encyclopedia of Otolaryngology, Head and Neck Surgery: Springer; 2013. pp. 583-98.

Additional Publication Citations

Technologies developed

Wolf JS, Isaiah A, inventors; Ultrasound Localization of Obstruction for Obstructive Sleep Apnea. United States patent grant 9,883,847

Wolf JS, Isaiah A, inventors;  Automatic Ultrasound Titration of Continuous Positive Airway Pressure (CPAP) Treatment for Sleep Apnea US 62/291,937

 

Research Interests

My primary interest is in the application of machine learning techniques to optimizing diagnosis and management of pediatric obstructive sleep apnea. Our collaborative group utilizes expertise that includes statistical learning, pediatric otolaryngology and sleep medicine, to reduce diagnostic errors and costs associated with diagnosis of pediatric OSA, as well as improve accuracy and patient compliance. 

My collaborators are: Dr Gautam Das (Database Exploration Laboratory, Dept of Computer Science and Engineering, University of Texas at Arlington) and Dr Ron Mitchell (Dept of Otolaryngology--Head and Neck Surgery, University of Texas Southwestern Medical Center)

Clinical Specialty Details

My interest spans the breadth of ear, nose and throat problems in infants and children, with an emphasis on management of pediatric sleep apnea.

Awards and Affiliations

Rhodes Scholarship

Duane Sewell, MD Resident Research Award 

Maryland Society of Otolaryngology Resident Research Award

Delegate, International Achievement Summit

Gerber Foundation Early Career Award

Bactroban Dermatology Prize

Cadila Health Care Prize in General Surgery

Dept of Biotechnology Award, Government of India

In the News

1. Seeing less helps the brain hear more: National Public Radio (NPR) Broadcast Feb 05 2014 

2. I was featured in The Why files, a University of Wisconsin publication

3. For the publication in Neuron, I received an Altmetric score of 356 (#2 in all journal submissions to Cell Press, 35 newspapers, 13 blogs, 20 tweets, 99th percentile in all research submissions worldwide in media attention compared to other articles of same age (article reported in BBC, Washington Post, NY Times, Scientific American, Nature etc.)