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Nevins W. Todd, MD

Academic Title:

Professor

Primary Appointment:

Medicine

Secondary Appointment(s):

Physiology

Additional Title:

Fellowship Program Director

Location:

Paca Pratt Building, 110 S Paca Street, 2nd floor

Phone (Primary):

(410) 328-8141

Fax:

(410) 328-0177

Education and Training

Davidson College, Davidson, North Carolina     1978-1982

University of Maryland School of Medicine        1982-1986

Internship, Residency and Chief Residency, Internal Medicine, Mercy Medical Center, Baltimore, MD  1986-1989

Fellowship, Division of Pulmonary & Critical Care Medicine, Duke University School of Medicine   1989-1992

Staff Physician, Pulmonary & Critical Care Medicine, Mercy Medical Center, Baltimore, Maryland   1992-2004

Assistant Professor, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 2005-2011

Fellowship Program Director, Pulmonary & Critical Care Medicine, University of Maryland School of Medicine, Baltimore, 2006-2014

Associate Professor, Department of Medicine, University of Maryland School of Medicine, Baltimore, 2011-present

Associate Professor, Department of Physiology, University of Maryland School of Medicine, Baltimore, 2013-present

 

Biosketch

Dr. Todd attends regularly on the inpatient and outpatient Pulmonary and Critical Care Medicine services at the University of Maryland Medical Center, the University of Maryland Mid-Town campus, and the Baltimore VA Medical Center. He is Director of the Clinical Care Network site at the University of Maryland as part of a national pulmonary fibrosis network through the Pulmonary Fibrosis Foundation. His educational responsibilities include the position as Co-Director of the Functional Systems course of University of Maryland School of Medicine.

Research/Clinical Keywords

Interstitial lung disease (ILD), pulmonary fibrosis, respiratory physiology

Highlighted Publications

Todd NW, Luzina IG, Atamas SP. Molecular and Cellular Mechanisms of Pulmonary Fibrosis. Fibrogenesis Tissue Repair 2012, 5:11.

Todd NW, Scheraga RG, Galvin JR, Iacono AT, Britt EJ, Luzina IG, Burke AP, Atamas SP. Lymphocyte Aggregates Persist and Accumulate in the Lungs of Patients with Idiopathic Pulmonary Fibrosis. J Inflamm Res 2013, 6: 63 - 70.

Luzina IG, Kopach P, Lockatell V, Kang PH, Nagarsekar A, Burke AP, Hasday JD, Todd NW, Atamas SP. Interleukin-33 Potentiates Bleomycin-induced Lung Injury. Am J Respir Cell Mol Biol 2013, 49:999-1008.

Kopach P, Lockatell V, Pickering EM, Haskell RE, Anderson RD, Hasday JD, Todd NW, Luzina IG, Atamas SP. IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism. J Biol Chem 2014, 289:11829-43.

Luzina IG, Lockatell V, Todd NW, Kopach P, Pentikis HS, Atamas SP. Pharmacological in vivo inhibition of S-nitrosoglutathione reductase attenuates bleomycin-induced inflammation and fibrosis. J Pharmacol Exp Ther 2015, 355:13-22.

Todd NW, Atamas SP, Luzina IG, Galvin JR. Permanent Alveolar Collapse is the Predominant Mechanism in Idiopathic Pulmonary Fibrosis. Expert Rev Respir Med 2015, 9:411-8.

Todd NW, Marciniak ET, Sachdeva A, Kligerman SJ, Galvin JR, Luzina IG, Atamas SP, Burke AP. Organizing Pneumonia/Non-specific Interstitial Pneumonia Overlap is associated with Unfavorable Lung Disease Progression. Respir Med.2015,109(11):1460-8.

Luzina IG, Lockatell V, Hyun SW, Kopach P, Kang PH, Noor Z, Liu A, Lillehoj EP, Lee C, Miranda-Ribera A, Todd NW, Goldblum SE, Atamas SP. Elevated Expression of NEU1 Sialidase in Idiopathic Pulmonary Fibrosis Provokes Pulmonary Collagen Deposition, Lymphocytosis, and Fibrosis. Am J Physiol Lung Cell Mol Physiol 2016, 310(10):L940-54.

Todd NW, Galvin JR, Sachdeva A, Luzina IG, Atamas SP, Burke AP. Microscopic Organizing Pneumonia and Cellular Nonspecific Interstitial Pneumonia are Widespread in Macroscopically Normal-Appearing Lung Tissue in Idiopathic Pulmonary Fibrosis. J Heart Lung Transplant 2016 [Epub ahead of print]

Research Interests

Dr. Todd's research interests are in the field of Interstitial Lung Disease (ILD) and Pulmonary Fibrosis. He works with Sergei Atamas, MD, PhD and Irina Luzina, MD, PhD from the Division of Rheumatology to advance understanding of these diseases. His research team uses animal models to understand basic mechanisms of disease, lung tissue from patients with ILD and pulmonary fibrosis to characterize molecular abnormalities, and clinical findings in patients (including histology and imaging) to characterize clinical outcomes and to correlate with basic science observations.

Awards and Affiliations

National Board of Medical Examiners (1987)

Internal Medicine, American Board of Internal Medicine (1989)

Pulmonary Disease, American Board of Internal Medicine (1992, 2002, 2013)

Critical Care Medicine, American Board of Internal Medicine (1993, 2003, 2013)