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Abdul K. Parchur, PhD

Academic Title:

Assistant Professor

Primary Appointment:

Radiation Oncology

Additional Title:

Medical Physicist

Email:

Abdul.Parchur@umm.edu

Location:

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, 22 S. Greene Street, Baltimore, MD 21201

Phone (Primary):

(410) 328 3770

Fax:

(410) 328 6911

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Education and Training

B.Sc.,  Physics  — Acharya Nagarjuna University, India (2003)

M.Sc., Physics  — Dr. Harisingh Gour Central University, India (2005)

Ph.D., Physics  — Dr. Harisingh Gour Central University, India (2010)

CAMPEP Certificate in Medical Physics  — Medical College of Wisconsin (2022)

Residency, Therapeutic Medical Physics — Medical College of Wisconsin (2025)

Biosketch

Dr. Abdul K. Parchur is an Assistant Professor in the Department of Radiation Oncology at the University of Maryland Medical Center. He earned his Ph.D. in Physics from Dr. Harisingh Gour Central University, India, and completed postdoctoral fellowships at Banaras Hindu University/Bhabha Atomic Research Centre, Utah State University, and the Medical College of Wisconsin, where he also trained in medical physics. His career is distinguished by a multidisciplinary approach that integrates physics, nanomedicine, biomedical engineering, and radiation oncology.

Dr. Parchur has authored over 80 peer-reviewed publications and book chapters, which have been cited more than 3,300 times, with an h-index of 30 and i-10 index of 46. His research has made significant contributions to nanomedicine, imaging science, and radiation oncology. Early in his career, he developed multimodal nanomaterials for imaging and photothermal therapy, including pioneering vascular interventional radiology–guided photothermal ablation of colorectal liver metastasis (ACS Nano, 2018). More recently, his work has demonstrated the potential of contrast-bearing nanoparticles to enhance the therapeutic effects of radiation in oral cancer (Technol Cancer Res Treat, 2023). His efforts in molecular imaging, particularly using near-infrared (NIR-II) and short-wave infrared (SWIR) probes, have advanced the ability to track tumor microenvironment, vascular function, and therapy response.

In radiation oncology, Dr. Parchur has emerged as a leader in MRI-guided adaptive radiation therapy (MRgART). He has developed machine learning frameworks to predict the necessity of daily online adaptive replanning (Radiother Oncol, 2022; Med Phys, 2023), deep learning auto-segmentation approaches (Phys Med Biol, 2023), and automated hallucination detection tools for synthetic CT in MR-only workflows (Phys Med Biol, 2025). These innovations are helping to bring artificial intelligence into clinical radiotherapy, improving efficiency, safety, and personalization of treatment.

His work has been recognized with international honors, including Best Oral Abstract awards at the World Conference on Interventional Oncology (2016, 2017) and Travel Awards from the World Molecular Imaging Society (2015, 2017, 2018). He is an active member of the American Association of Physicists in Medicine (AAPM), the American Society for Radiation Oncology (ASTRO), and the Radiological Society of North America (RSNA). He also serves as a reviewer for more than 40 scientific journals and as guest editor for IEEE Transactions on Nanobioscience, Nanomaterials, Frontiers in Medicine, and Frontiers in Oncology.

As a faculty member at University of Maryland Medical Center, Dr. Parchur’s long-term research vision is to advance precision radiation oncology through Image-guided adaptive therapy, AI-based clinical tools, and radiopharmaceutical approaches to improve tumor targeting and therapeutic outcomes. His overarching goal is to translate multidisciplinary innovations into clinically impactful strategies that improve cancer care.

Research/Clinical Keywords

MRI-guided adaptive radiation therapy, MR-guided radiation therapy, MRI-only workflow, Synthetic CT, AI-generated sCT, Hallucination detection, Air segmentation, Adaptive radiotherapy protocols, Radiation therapy QA, AI-based radiotherapy QA, Machine learning, In-vivo dosimetry, IMRT, VMAT, SRS, SBRT, TBI, Proton therapy, Radiation oncology, Nanomedicine, Hyperthermia therapy, Tumor microenvironment

Highlighted Publications

Parchur AK, Sharma G, Jagtap JM, Gogineni VR, LaViolette PS, Flister MJ, et al. Vascular Interventional Radiology Guided Photothermal Therapy of Colorectal Cancer Liver Metastasis with Theranostic Gold Nanorods. ACS Nano. 2018;12(7):6597–6611.

Ahunbay E, Parchur AK, Paulson E, Chen X, Omari E, Li XA. Development and implementation of an automatic air delineation technique for MRI-guided adaptive radiation therapy. Phys Med Biol. 2022;67(14):145011

Parchur AK, Lim S, Nasief HG, Omari EA, Zhang Y, Paulson ES, et al. Auto‐detection of necessity for MRI‐guided online adaptive replanning using a machine learning classifier. Med Phys. 2023;50(1):440–448.

Nasief HG, Parchur AK, Omari E, Zhang Y, Chen X, Paulson E, et al. Predicting necessity of daily online adaptive replanning based on wavelet image features for MRI guided adaptive radiation therapy. Radiother Oncol. 2022;176:165–171.

Parchur AK, Zarenia M, Gage C, Paulson ES, Ahunbay E. Automated hallucination detection for synthetic CT images used in MR-only radiotherapy workflows. Phys Med Biol. 2025; 70:05NT01.

Sharma G, Razeghi Kondelaji MH, Sharma GP, Hansen C, Parchur AK, Shafiee S, et al. X-ray and MR contrast bearing nanoparticles enhance the therapeutic response of image-guided radiation therapy for oral cancer. Technol Cancer Res Treat. 2023;22:15330338231189593.

Additional Publication Citations

Please check Google Scholar for all publications

  1. Parchur AK, Ningthoujam RS. Preparation and structure refinement of Eu³⁺ doped CaMoO₄ nanoparticles. Dalton Trans. Royal Society of Chemistry (RSC); 2011 Aug 7;40(29):7590–7594. 
  2. Parchur AK, Ningthoujam RS, Rai SB, Okram GS, Singh RA, Tyagi M, Gadkari SC, Tewari R, Vatsa RK. Luminescence properties of Eu³⁺ doped CaMoO₄ nanoparticles. Dalton Trans J Inorg Chem. Royal Society of Chemistry; 2011;40(29):7595–7601.
  3. Parchur AK, Ningthoujam RS. Behaviour of electric and magnetic dipole transitions of Eu³⁺, 5D0→7F0 and Eu-O charge transfer band in Li+ co-doped YPO₄:Eu³⁺. RSC Advances. 2012;2(29):10859–10868.
  4. Parchur AK, Ningthoujam RS. Preparation, microstructure and crystal structure studies of Li+ co-doped YPO₄:Eu³⁺. RSC Advances. 2012;2(29):10854–10858.
  5. Parchur AK, Prasad AI, Ansari AA, Rai SB, Ningthoujam RS. Luminescence properties of Tb³⁺-doped CaMoO₄ nanoparticles: annealing effect, polar medium dispersible, polymer film and core–shell formation. Dalton Trans. 2012;41(36):11032–11045.
  6. Parchur AK, Prasad AI, Rai SB, Ningthoujam RS. Improvement of blue, white and NIR emissions in YPO₄:Dy³⁺ nanoparticles on co-doping of Li+ ions. Dalton Trans. 2012;41(45):13810–13814.
  7. Parchur AK, Prasad AI, Rai SB, Tewari R, Sahu RK, Okram GS, et al. Observation of intermediate bands in Eu³⁺ doped YPO₄ host: Li+ ion effect and blue to pink light emitter. AIP Advances. 2012;2:032119.
  8. Ansari AA, Hasan TN, Syed NA, Labis JP, Parchur AK, Shafi G, et al. In-vitro cyto-toxicity, geno-toxicity, and bio-imaging evaluation of one-pot synthesized luminescent functionalized mesoporous SiO₂@Eu(OH)₃ core-shell microspheres. Nanomedicine: Nanotechnology, Biology and Medicine. 2013;9(8):1328–1335.
  9. Prasad AI, Parchur AK, Juluri RR, Jadhav N, Pandey BN, Ningthoujam RS, et al. Bi-functional properties of Fe₃O₄@YPO₄:Eu hybrid nanoparticles: hyperthermia application. Dalton Trans. 2013;42(14):4885–4996.
  10. Singh BP, Parchur AK, Singh RK, Ansari AA, Singh P, Rai SB. Structural and up-conversion properties of Er³⁺ and Yb³⁺ co-doped Y₂Ti₂O₇ phosphors. Phys Chem Chem Phys. 2013;15(10):3480–3489.
  11. Ansari AA, Alam M, Parchur AK. Nd-doped calcium molybdate core and particles: synthesis, optical and photoluminescence studies. Appl Phys A. 2014;116:1719–1728.
  12. Ansari AA, Parchur AK, Alam M, Azzeer A. Effect of surface coating on optical properties of Eu³⁺-doped CaMoO₄ nanoparticles. Spectrochim Acta A Mol Biomol Spectrosc. 2014;131:30–36.
  13. Ansari AA, Parchur AK, Alam M, Azzeer A. Structural and photoluminescence properties of Tb-doped CaMoO₄ nanoparticles with sequential surface coatings. Mater Chem Phys. 2014;147(3):715–721.
  14. Ansari AA, Parchur AK, Alam M, Labis J, Azzeer A. Influence of Surface Coating on Structural and Photoluminescent Properties of CaMoO₄:Pr Nanoparticles. J Fluoresc. 2014;24(4):1253–1262.
  15. Parchur AK, Ansari AA, Singh BP, Hasan TN, Syed NA, Rai SB, et al. Enhanced luminescence of CaMoO₄:Eu by core@shell formation and its hyperthermia study after hybrid formation with Fe₃O₄: cytotoxicity assessment on human liver cancer cells and mesenchymal stem cells. Integr Biol (Camb). 2014;6(1):53–64.
  16. Singh BP, Parchur AK, Ningthoujam RS, Ansari AA, Singh P, Rai SB. Influence of Gd³⁺ co-doping on structural property of CaMoO₄:Eu nanoparticles. Dalton Trans. 2014;43:4770–4778.
  17. Singh BP, Parchur AK, Ningthoujam RS, Ansari AA, Singh P, Rai SB. Enhanced photoluminescence in CaMoO₄: Eu³⁺ by Gd³⁺ co-doping. Dalton Trans. 2014;43:4779–4789.
  18. Singh BP, Parchur AK, Ningthoujam RS, Ramakrishna PV, Singh S, Singh P, et al. Enhanced up-conversion and temperature-sensing behaviour of Er³⁺ and Yb³⁺ co-doped Y₂Ti₂O₇ by incorporation of Li⁺ ions. Phys Chem Chem Phys. 2014;16(41):22665–22676.
  19. Gogineni VR, Jagtap JM, Parchur AK, Sharma G, Joshi A, White SB. Photothermal Ablation: A Perspective on Technique. Interv Oncol 360. 2015;3(12):E141–E147.
  20. Ansari AA, Parchur AK, Kumar B, Rai SB. Influence of Shell Formation on Morphological Structure, Optical and Emission Intensity on Aqueous Dispersible NaYF₄:Ce/Tb Nanoparticles. J Fluoresc. 2016;26(4):1151–1159.
  21. Ansari AA, Parchur AK, Kumar B, Rai SB. Highly aqueous soluble CaF₂:Ce/Tb nanocrystals: Effect of surface functionalization on structural, optical band gap and photoluminescence properties. J Mater Sci Mater Med. 2016;27:178.
  22. Li Q, Parchur AK, Zhou A. In-vitro biomechanical properties, fluorescence imaging, surface-enhanced Raman spectroscopy, and photothermal therapy evaluation of luminescent functionalized CaMoO₄:Eu@Au hybrid nanorods on human lung adenocarcinoma epithelial cells. Sci Technol Adv Mater. 2016;17(1):345–360.
  23. Parchur AK, Li Q, Zhou A. Near-infrared photothermal therapy of Prussian-blue-functionalized lanthanide-ion doped inorganic/plasmonic multifunctional nanostructures for the selective targeting of HER2-expressing breast cancer cells. Biomater Sci. 2016;4:1781–1791.
  24. Belkhir NH, Toncelli A, Parchur AK, Alves E, Maalej R. Efficient temperature sensing using photoluminescence of Er/Yb implanted GaN thin films. Sens Actuators B Chem. 2017;248:769–776.
  25. Flister MJ, Tsaih S-W, Stoddard A, Plasterer C, Jagtap J, Parchur AK, et al. Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer. Breast Cancer Res Treat. 2017;165:53–64.
  26. Jagtap J, Patil N, Parchur AK, Pantola C, Agarwal A, Pandey K, et al. Effective screening and classification of cervical precancer biopsy imagery. IEEE Trans Nanobiosci. 2017;16(8):687–693.
  27. Maalej R, Parchur AK. Editorial Special Section on Engineering Sciences in Biology and Medicine. IEEE Trans Nanobiosci. 2017;16(8):647.
  28. Jaidip J, Gayatri S, Parchur AK, Venkateswara G, Carmen BSW, Flister MJ, et al. Methods for detecting host genetic modifiers of tumor vascular function using dynamic near-infrared fluorescence imaging. Biomed Opt Express. 2018;9(2):543.
  29. Parchur AK, Sharma G, Jagtap JM, Gogineni VR, LaViolette PS, Flister MJ, et al. Vascular Interventional Radiology Guided Photothermal Therapy of Colorectal Cancer Liver Metastasis with Theranostic Gold Nanorods. ACS Nano. 2018;12(7):6597–6611.
  30. Xiao L, Parchur AK, Gilbertson TA, Zhou A. SERS-fluorescence bimodal nanoprobes for in vitro imaging of the fatty acid responsive receptor GPR120. Anal Methods. 2018;10:22–29
  31. Parchur AK, Jagtap JM, Sharma G, Gogineni V, White SB, Joshi A. Remotely triggered nanotheranostics. Nanotheranostics for Cancer Applications. 2019:429–460.
  32. Thorat ND, Townely H, Brennan G, Parchur AK, Silien C, Bauer J, et al. Progress in remotely triggered hybrid nanostructures for next-generation brain cancer theranostics. ACS Biomater Sci Eng. 2019;5(6):2669–2687.
  33. Zimmerman KC, Sharma G, Parchur AK, Joshi A, Schmidt TG. Experimental investigation of neural network estimator and transfer learning techniques for K-edge spectral CT imaging. Med Phys. 2019;47(2):541–551.
  34. Ansari AA, Khan S, Parchur AK, Kumar B, Kumar A, Raish M, et al. In-vitro cytotoxicity evaluation of surface design luminescent lanthanide core/shell nanocrystals. Arab J Chem. 2020;13(1):1259–1270.
  35. Gogineni VR, Maddirela DR, Park WR, Jagtap JM, Parchur AK, Sharma G, et al. Localized and triggered release of oxaliplatin for the treatment of colorectal liver metastasis. J Cancer. 2020;11(23):6982–6991.
  36. Parchur AK, Fang Z, Jagtap JM, Sharma G, Hansen C, Shafiee S, et al. NIR-II window tracking of hyperglycemia-induced intracerebral hemorrhage in cerebral cavernous malformation deficient mice. Biomater Sci. 2020;8:5133–5144.
  37. Rana U, Callan E, Entringer B, Michalkiewicz T, Joshi A, Parchur AK, et al. AMP-Kinase dysfunction alters Notch ligands to impair angiogenesis in neonatal pulmonary hypertension. Am J Respir Cell Mol Biol. 2020;62(6):719–731.
  38. Sharma G, Jagtap JM, Parchur AK, Gogineni VR, Ran S, Bergom C, et al. Heritable modifiers of the tumor microenvironment influence nanoparticle uptake, distribution, and response to photothermal therapy. Theranostics. 2020;10(12):5368–5382.
  39. Ansari AA, Parchur AK, Labis JP, Shar MA. Physiochemical characterization of highly biocompatible and colloidal LaF₃:Yb/Er upconversion nanoparticles. Photochem Photobiol Sci. 2021;20(9):1195–1208.
  40. Ansari AA, Parchur AK, Labis JP, Shar MA, Khan A. Highly hydrophilic CaF₂:Yb/Er upconversion nanoparticles: Structural, morphological, and optical properties. J Fluorine Chem. 2021:109820.
  41. Ansari AA, Parchur AK, Nazeeruddin MK, Tavakoli MM. Luminescent lanthanide nanocomposites in thermometry: Chemistry of dopant ions and host matrices. Coord Chem Rev. 2021;444:214040.
  42. Ansari AA, Parchur AK, Thorat ND, Chen G. New advances in pre-clinical diagnostic imaging perspectives of functionalized upconversion nanoparticle-based nanomedicine. Coord Chem Rev. 2021;440:213971.
  43. Jagtap J, Audi S, Razeghi-Kondelaji MH, Fish BL, Hansen C, Narayan J, et al. A rapid dynamic in vivo near-infrared fluorescence imaging assay to track lung vascular permeability after acute radiation injury. Am J Physiol Lung Cell Mol Physiol. 2021;320(3):L436–L450.
  44. Sharma M, Rana U, Joshi C, Michalkiewicz T, Afolayan A, Parchur AK, et al. Decreased cyclic guanosine monophosphate–protein kinase G signaling impairs angiogenesis in a lamb model of persistent pulmonary hypertension of the newborn. Am J Respir Cell Mol Biol. 2021;65(5):555–567.
  45. Thorat N, Pricl S, Parchur AK, Somvanshi SB, Li Q, Umrao S, et al. Safeguarding COVID-19 and cancer management: Drug design and therapeutic approach. Open Res Eur. 2021;1:77.
  46. Ahunbay E, Parchur AK, Paulson E, Chen X, Omari E, Li XA. Development and implementation of an automatic air delineation technique for MRI-guided adaptive radiation therapy. Phys Med Biol. 2022;67(14):145011.
  47. Ansari AA, Parchur AK, Chen G. Surface modified lanthanide upconversion nanoparticles for drug delivery, cellular uptake mechanism, and current challenges in NIR-driven therapies. Coord Chem Rev. 2022;457:214423.
  48. Nasief HG, Parchur AK, Omari E, Zhang Y, Chen X, Paulson E, et al. Predicting necessity of daily online adaptive replanning based on wavelet image features for MRI guided adaptive radiation therapy. Radiother Oncol. 2022;176:165–171.
  49. Ahunbay E, Parchur AK, Xu J, Thill D, Paulson ES, Li XA. Automated deep learning auto-segmentation of air volumes for MRI-guided online adaptive radiation therapy of abdominal tumors. Phys Med Biol. 2023;68(12):125011.
  50. Ansari AA, Khan MAM, Singh BP, Parchur AK. Upconversion nanoparticles: Influence of the host lattices on crystallographic and luminescent properties. J Mater Sci Mater Electron. 2023;34(22):1625.
  51. Ansari AA, Khan MAM, Singh BP, Parchur AK. Influence of the host lattices on photoluminescent properties of the Ce/Tb doped CaF₂, NaYF₄, and NaGdF₄ nanoparticles. J Fluorine Chem. 2023;270:110174.
  52. Parchur AK, Lim S, Nasief HG, Omari EA, Zhang Y, Paulson ES, et al. Auto‐detection of necessity for MRI‐guided online adaptive replanning using a machine learning classifier. Med Phys. 2023;50(1):440–448.
  53. Sharma G, Razeghi Kondelaji MH, Sharma GP, Hansen C, Parchur AK, Shafiee S, et al. X-ray and MR contrast bearing nanoparticles enhance the therapeutic response of image-guided radiation therapy for oral cancer. Technol Cancer Res Treat. 2023;22:15330338231189593.
  54. Ansari AA, Lv R, Gai S, Parchur AK, Solanki PR, Ansari ZA, et al. ZnO nanostructures—Future frontiers in photocatalysis, solar cells, sensing, supercapacitor, fingerprint technologies, toxicity, and clinical diagnostics. Coord Chem Rev. 2024;515:215942.
  55. Ansari AA, Parchur AK, Li Y, Jia T, Lv R, Wang Y, et al. Cytotoxicity and genotoxicity evaluation of chemically synthesized and functionalized upconversion nanoparticles. Coord Chem Rev. 2024;504:215672.
  56. Hansen C, Jagtap J, Parchur AK, Sharma G, Shafiee S, Sinha S, et al. Dynamic multispectral NIR/SWIR for in vivo lymphovascular architectural and functional quantification. J Biomed Opt. 2024;29(10):106001.
  57. Kondelaji MHR, Sharma GP, Jagtap J, Shafiee S, Hansen C, Gasperetti T, et al. 2nd window NIR imaging of radiation injury mitigation provided by reduced Notch-Dll4 expression on vasculature. Mol Imaging Biol. 2024;26(1):124–137.
  58. Li B, Ansari AA, Parchur AK, Lv R. Exploring the influence of polymeric and non-polymeric materials in synthesis and functionalization of luminescent lanthanide nanomaterials. Coord Chem Rev. 2024;514:215922.
  59. Parchur AK, Zarenia M, Gage C, Paulson ES, Ahunbay E. Automated hallucination detection for synthetic CT images used in MR-only radiotherapy workflows. Phys Med Biol. 2025; 70:05NT01.
  60. Ansari AA, Lv R, Parchur AK, Dhayal M. Enhancing biosensor sensitivity with CeO2 nanocomposites for biomedical and environmental applications. Chem Eng J. 2025; 512:162526.

Links of Interest

LinkedIn : https://www.linkedin.com/in/aparchur/

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