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Regina A. Macatangay, MD

Academic Title:

Associate Professor

Primary Appointment:

Pediatrics

Additional Title:

Clerkship Director, Pediatrics

Location:

North Hospital, N5E16

Phone (Primary):

410-328-2808

Fax:

410-328-0571

Education and Training

Undergraduate School:  University of Maryland Baltimore County

Medical Degree School:  University of Maryland School of Medicine

Residency:    University of Maryland Hospital for Children, University of Maryland Medical Center

Fellowship:   Pediatric Hematology/Oncology at Memorial Sloan-Kettering Cancer Center and New York Presbyterian Hospital – Weill Cornell Medical College

Biosketch

I completed my Pediatric residency and chief residency training program at the University of Maryland Medical Center and my joint fellowship training in Pediatric Hematology/Oncology at Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College in New York. I worked in the lab of Christopher Y. Park investigating the role of microRNAs in chemoresistance of pediatric leukemia.

 As a fellow, I fostered a clinical interest in neuro-oncology and Wilms tumor and worked with Dr. James Bussel on a clinical project involving Radioulnar Synostosis-Hematology Syndrome. After moving back to Baltimore, I worked with Carol Greene to establish a joint Hematology/Oncology-Genetics clinic and I am continuing clinical research in sickle cell anemia and inherited disorders of the blood. I serve as the director of the Pediatric clerkship at the University of Maryland School of Medicine and act as a professional and clinical mentor to high school students, undergraduate students through the Meyerhoff Scholarship Program at UMBC (M8), medical students, and Pediatric residents. 

Research/Clinical Keywords

Sickle cell disease Pediatric Hematology Pediatric Oncology

Highlighted Publications

Dagalakis U, Hammershaimb E, McArthur MA, Macatangay RA. SARS-CoV-2 infection in pediatric patient with hemoglobin SC disease. Pediatr Blood Cancer. 2020 Nov;67(11):e28430. doi: 10.1002/pbc.28430. Epub 2020 Aug 9. PMID: 32776470; PMCID: PMC7435506.

Howard B, Biggs JM, Crist M, Kishk OA, Carter RG, Macatangay RA. Interprofessional approach to educating medical students on pediatric medication taste and palatability. Health, Interprofessional Practice and Education. 2021 Jul 7;4(2).  doi: 10.7710/2641-1148.2148

Jeyaraju M, Macatangay RA, Munchel AT, York TA, Montgomery EA, Kallen ME. Embryonal Rhabdomyosarcoma with Posttherapy Cytodifferentiation and Aggressive Clinical Course. Case Rep Pathol. 2021 Nov 8;2021:1800854. doi: 10.1155/2021/1800854. PMID: 34790419; PMCID: PMC8592761.

Butt H, Munchel A, York T, Macatangay R. Multi-Generational Review of Oncologic Tumors in a Family With TP53 Mutation Presenting With a Pediatric Patient With Osteosarcoma and Lung Acinar Adenocarcinoma. Cureus. 2021 Aug 18;13(8):e17271. doi: 10.7759/cureus.17271. PMID: 34540492; PMCID: PMC8448272.

Sandler E, Crowley, H, Krishnan, V, Aljutali, H, Aljuaid, M, R. Macatangay. Simultaneous Presentation of Wilms Tumor and Obstructing Duodenal-Jejunal Hematoma: A Case Report. Pediatric Urology Case Reports 2024; 11(1):356-62. doi: 10.14534/j-pucr.20222675631

Additional Publication Citations

Watts, TL, Kiser, TD, Macatangay, RA, Goldblum, SE Fasano, A. Dissociation of ZO1-occludin complex is involved in zonula occludens toxin (Zot)-mediated disassembly of intestinal tight junctions. Gastroenterology. 2001; 5(120), p.A699. (provided data)

Clemente MG, De Virgiliis S, Kang JS, Macatagney R*, Musu MP, Di Pierro MR, Drago S, Congia M, Fasano A. Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function. Gut. 2003 Feb;52(2):218-23. doi: 10.1136/gut.52.2.218. PMID: 12524403; PMCID: PMC1774976. (provided data) *name misspelling noted3.              DiChiacchio L, Shockcor NM, Macatangay R, Strauch E. Extensive synchronous bilateral Wilms tumor treated with nephron sparing surgery. Urol Case Rep. 2018 Mar 21;18:16-18. doi: 10.1016/j.eucr.2018.02.008. PMID: 29686964; PMCID: PMC5910529. (provided clinical expertise and manuscript edits)

Mininni J, Singh Z, Strauch E, Macatangay RA, Kallen ME. Warthin–Finkeldey-like cells in a lymph node from a child with Li-Fraumeni syndrome. J Hematopathol. 2019 Dec; 12(4):215-6. doi: 10.1007/s12308-019-00366-8  (provided clinical expertise and manuscript edits)

Ghosh, T, Canham, L, Macatangay, R. Establishing a role for asthma management as adjuvant therapy for vaso-occlusive crisis. American Society of Pediatric Hematology/Oncology (ASPHO) Hyatt Regency Minneapolis, Minneapolis, MN May 11-14, 2016. Pediatr Blood Cancer. 2016 Jun;63 Suppl 1(Suppl 1):S47 doi: 10.1002/pbc.25998. Erratum in: Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26583. PMID: 27077670; PMCID: PMC7167840.

Canham, L, Ghosh, T, Grant, M, Munchel, A, Macatangay, R. Establishing a role for asthma management as adjuvant therapy for vaso-occlusive crisis: pulmonary risk stratification and proposed interventions. 2016 American Society of Hematology Annual Meeting. Blood, 128(22), 4866.

Canham, L, Grant, M, Ghosh, T, Munchel, A, Macatangay, R. Institutional analysis of obstructive pulmonary disease intervention as potential adjuvant therapy for vaso-occlusive crisis. 2017 American Society for Pediatric Hematology and Oncology Annual Meeting, April 2017. Pediatr Blood Cancer (Vol. 64). S25-S25. doi: 10.1002/pbc.26591

Grant, M, Macatangay, R, Holloway, A. Use of extracorporeal membrane oxygenation in a patient with newly diagnosed acute promyelocytic leukemia despite coagulopathy and hemorrhage. American Society of Pediatric Hematology/Oncology (ASPHO), David L. Lawrence Convention Center, Pittsburgh, PA, May 2-5, 2018. Pediatr Blood Cancer. 2018 Jun;65 Suppl 1(Suppl 1):e27057. doi: 10.1002/pbc.27057. PMID: 29603868; PMCID: PMC7167873

Dagalakis, U, Munchel, A, Macatangay, R. Patient with Sickle Cell Trait has Unusual Presentation on State Newborn Screen. Accepted to 2020 American Society for Pediatric Hematology and Oncology Annual Meeting, May 2020 (cancelled due to Coronavirus pandemic; published electronically). Pediatr Blood Cancer(Vol. 67, pp. S54-S54).  doi: 10.1002/pbc.28321

Racherla, V, Lanlokun, M, Wisniewski, E, Nemirovsky, A, Macatangay, R, York, T. Pancreatic neuroendocrine tumor with liver metastasis in a 9 year old patient: A case report. 2020 American Society for Pediatric Hematology and Oncology Annual Meeting, May 2020 (cancelled due to Coronavirus pandemic). Pediatr Blood Cancer (Vol. 67, pp. S134-S135). doi: 10.1002/pbc.28321

Dagalakis, U, Butt, H, Davis, N, Macatangay, R. Investigation of Chest X-Ray Use in the Emergency Department in Pediatric Patients with Sickle Cell Disease Presenting with Fever Compared to Age Matched Controls. American Society of Hematology Annual Meeting, December 2020 (hosted virtually due to Coronavirus pandemic). Blood 136 (2020): 26.

Jung, M and Macatangay, R. Platelet Delta Storage Pool Disorder:  A Multigenerational Case Report. American Society of Pediatric Hematology/Oncology (ASPHO) 2021 Paper and Poster Abstracts. Pediatr Blood Cancer. 2021 Jun;68 Suppl 3:e29060. doi: 10.1002/pbc.29060. PMID: 33881204. (p. S118-S119).

Butt, H, Munchel, A, Macatangay, R. Case Report:  TP53 Mutation In A Pediatric Patient With Osteosarcoma and Lung Acinar Adenocarcinoma.  2021 American Society of Pediatric Hematology/Oncology (ASPHO) 2021 Paper and Poster Abstracts. Pediatr Blood Cancer. 2021 Jun;68 Suppl 3:e29060. doi: 10.1002/pbc.29060. PMID: 33881204. (p. S173-S174).

Howard, B, Langbaum, M, Macatangay, R. Novel Presentation of Factor V Leiden Mutation In A Neonate with Umbilical Vein Varix. American Society of Pediatric Hematology/Oncology (ASPHO) 2021 Paper and Poster Abstracts. Pediatr Blood Cancer. 2021 Jun;68 Suppl 3:e29060. doi: 10.1002/pbc.29060. PMID: 33881204. (p. S115).

Sandler, E, Crowley, H, Macatangay, R. Unusual Presentation of Patient With Wilms Tumor and Obstructing Duodenal Hematoma.  American Society of Pediatric Hematology/Oncology (ASPHO) 2021 Paper and Poster Abstracts. Pediatr Blood Cancer. 2021 Jun;68 Suppl 3:e29060. doi: 10.1002/pbc.29060. PMID: 33881204 (p. S169-S169).

Dagalakis, U and Macatangay, R. Atypical Presentation and Management of Juvenile Xanthogranuloma.  American Society of Pediatric Hematology/Oncology (ASPHO) 2021 Paper and Poster Abstracts. Pediatr Blood Cancer. 2021 Jun;68 Suppl 3:e29060. doi: 10.1002/pbc.29060. PMID: 33881204. (p. S160-S160).

Clinical Specialty Details

Co-Director Pediatric Hematology/Oncology and Genetics Program

Awards and Affiliations

Awards

2009                G. Bowers Mansdorfer, MD Award - awarded for exhibiting the qualities of a learned, caring and committed pediatrician as selected by the Pediatric staff of Mercy Medical Center

2009                Resident Inductee, Arnold P. Gold Foundation Gold Humanism Honor Society – nominated by medical students for humanism in medicine

2014                Alexander J. Shaffer Teaching Award - awarded for outstanding contribution to housestaff education by the Pediatric Housestaff of the UMMC

2016-2023       Baltimore Top Doc, Pediatric Hematology/Oncology, Baltimore Magazine

2019                Faculty Marshal – UMSOM Commencement – selected by the Class of 2019

2020                Student Marshal – UMSOM Commencement – selected by the Class of 2020

2023                Alumna Inductee, Alpha Omega Alpha Honor Medical Society, UMSOM

2023                Outstanding Volunteer Service Award, Swansfield Elementary School, Howard County Public School System

2024                Golden Apple Award for Best Clinical Faculty – UMSOM Commencement – selected by the Class of 2024

2025                Faculty Hooder – UMSOM Commencement – selected by the Class of 2025

 

Affiliations

2009-present   Member, Arnold P Gold Foundation Humanism Honor Society

2010-present   Member, Children’s Oncology Group

2011-present   Member, American Society of Hematology

2012-present  Member, American Society of Pediatric Hematology and Oncology

2015-2016       Member, Pediatric Blood and Marrow Transplant Consortium

2015-present   Member, Counsel on Medical Student Education in Pediatrics (COMSEP)

2023-present   Member, Alpha Omega Alpha Honor Medical Society

Professional Activity

2013-present   Presenter, Pediatric Oncology Tumor Board; UMSOM

2013-present   Attending Representative, Palliative Care Team; UMCH

2013-present   Interviewer, UMCH Residency Applicants

2013-present   Member, Education Task Force, UMCH

2014-present   Pediatric Clerkship Member, Curriculum Coordinating Committee; UMSOM

2014-present   Pediatric Clerkship Member, Advancement Committee; UMSOM

2014-present   Interviewer for Medical School Applicants, Admissions Committee; UMSOM

2014-present   Director, Pediatric Clerkship; UMSOM

2015-present   Member, Admissions Committee; UMSOM

2015-2024       Clerkship Director Participant, Liaison Committee on Medical Education (LCME) Institutional Review; UMSOM

2018-present   Faculty Advisor, Pediatric Interest Group; UMSOM

2019-present   Division Representative, Epic Steering Committee; Division of Pediatric Hematology/Oncology

2020-present   Applicant Reviewer, Admissions Committee; UMSOM

2020-present   Vice Chair, Clinical Years Committee; UMSOM

2021-present   Member, Medical Education Leadership Academy; UMSOM

2022-present   Subcommittee Member, LCME Educational Resources (ER); UMSOM

2023-present   Member, Education Strategic Plan Committee; UMSOM

2023-present   Member, Medical Education Continuous Quality Improvement Committee; UMSOM