Academic Title:
Professor
Primary Appointment:
Epidemiology & Public Health
Email:
Location:
725 W Lombard St, Baltimore, MD 21201
Education and Training
Predoctoral
1980 Master of Medicine, Peking Union Medical College, China
Doctoral/graduate
1985 Doctor of Medicine, Peking Union Medical College, China
Postdoctoral
1987 Master of Public Health, Uniformed Services University, DOD
1987 Business Administration, Six courses finished, New York Institute of Technology, New York City, NY
2008 Business of Medicine, Johns Hopkins Carey Business School, Baltimore, MD
Biosketch
Dr. Shenghan Lai is a Professor of Epidemiology at University of Maryland, and an Adjunct Professor of Epidemiology and Medicine at Johns Hopkins Medicine, with more than three decades of experience leading NIH-funded cohort studies focused on HIV, substance use, cardiovascular disease, and neurocognition in underserved populations. Since 2000, he has built and maintained the Baltimore Heart Study and related cohorts, following more than 1,500 predominantly African American participants with exceptionally low attrition and integrating advanced imaging (CT, MRI), biomarkers, and detailed behavioral assessments. This sustained work has produced nearly 300 peer-reviewed publications and a strong track record in rigorous longitudinal design, high-retention community engagement, and complex multimodal analyses directly relevant to life-course brain health and dementia risk.
His current NIDA-funded studies (U01 DA040325; R01 DA058438) investigate how HIV infection, chronic cocaine use, and long-term antiretroviral therapy influence subclinical cardiovascular disease, brain structure and function (including hippocampal volume, DTI, and ASL MRI), and cognitive performance. These projects require careful control of confounding, sophisticated mixed-effects modeling, and harmonization of multi-timepoint imaging and clinical data—skills that translate directly to the proposed secondary analysis of ABCD. In preliminary work that motivates this application, my team has shown that higher EPA levels are associated with larger hippocampal volume specifically among adults with low episodic memory, and he has replicated this pattern in the longitudinal ADNI cohort. These findings suggest a modifiable, vulnerability-dependent pathway between omega-3 status, hippocampal integrity, and memory that may begin earlier in life.
Research/Clinical Keywords
Epidemiology, drug abuse, HIV/AIDS, STIs, prevention and intervention, effects of HIV infection and cocaine use on sub-clinical cardiovascular disease, preventive cardiology, medical consequences of HIV infection, and international health.
Highlighted Publications
Kolossváry M, Fishman EK, Gerstenblith G, Bluemke DA, Mandler RN, Celentano D, Kickler TS, Bazr S, Chen S, Lai S, Lai H. Cardiovascular risk factors and illicit drug use may have a more profound effect on coronary atherosclerosis progression in people living with HIV. Eur Radiol. 2021 May;31(5):2756-2767. doi: 10.1007/s00330-021-07755-7. Epub 2021 Mar 3. PubMed PMID: 33660033; PubMed Central PMCID: PMC9125805.
Chen DH, Kolossváry M, Chen S, Lai H, Yeh HC, Lai S. Long-term cocaine use is associated with increased coronary plaque burden - a pilot study. Am J Drug Alcohol Abuse. 2020 Nov 1;46(6):805-811. doi: 10.1080/00952990.2020.1807558. Epub 2020 Sep 29. PubMed PMID: 32990047; PubMed Central PMCID: PMC8311667.
Li J, Lai H, Chen S, Kickler T, Lai S. Cocaine use modifies the association between antiretroviral therapy and endothelial dysfunction among adults with HIV infection. J Med Virol. 2019 Sep;91(9):1660-1667. doi: 10.1002/jmv.25507. Epub 2019 May 29. PubMed PMID: 31144332; PubMed Central PMCID: PMC6642012.
Lai S, Heaphy CM, Rizzo AJ, Celentano DD, Gerstenblith G, Li J, Moore RD, Treisman G, Chen S, Foster P, Kickler T, Lai H. Cocaine use may induce telomere shortening in individuals with HIV infection. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):11-17. doi: 10.1016/j.pnpbp.2018.01.015. Epub 2018 Feb 2. PubMed PMID: 29410247; PubMed Central PMCID: PMC5880737.
Additional Publication Citations
- Lin QS, Sen QC, Lai S. The relationship between the chemical components in the blood and aging. Acta Aced Med Sin 1983;5(5):303-305.
- Wu XG, Lai SH. Multivariate analysis of the risk factors of coronary heart disease among 988 male workers of Beijing Capital Steel and Iron Complex. Chinese Journal of Cardiology 1983;11(1):28-31.
- Liu LS, Tao SC, Lai S. The relationship between urinary excretion and blood pressure in various regions of China. Bulletin of WHO 1984; 62(2):255-260.
- Liu LS, Zheng DY, Lai S. Variability in 24-hour urine sodium excretion in Chinese adults. Chinese Med J 1986;99(5):424-426.
- Liu LS, Lai S. Relationship between salt excretion and blood pressure in various regions of China: Part 2. Bulletin of WHO 1986;64(5):729-733.
- Schlesselman JJ, Stadel BV, Murray P, Lai S. Breast cancer in relation to type of estrogen contained in oral contraceptives. Contraception 1987; 36(6):595-613.
- Wu XG, He, L, JS Hao, NG Chen, Lai S, SY Wang, XH Yu. The risk factors for stroke among male workers of Beijing capital steel and iron complex. Chinese J Cardiol 1987; 15(4):239.
- Schlesselman JJ, Stadel BV, Murray P, Lai S. Breast cancer in relation to early oral contraceptives. No evidence of a latent effect. JAMA 1988; 259:1828-1833.
- Stadel BV, Lai S, Schlesselman JJ, Murray P. Oral contraceptives and premenopausal breast cancer in nulliparous women. Contraception 1988; 38(3):287-299.
- Lai S, Tang YC, He WL, Mo PS, He GQ. Urinary electrolytes and blood pressure in three Yi farmer populations in China. Hypertension 1989;13:22-30.
- McCoy HV, McKay CY, Hermanns L, Lai S. Sexual behaviors and the risk of HIV infection. Am Behav Sci 1990;33(4):432-450.
- Page JB, Lai S, Chitwood D, Klimas NG, Smith PC, Fletcher MA. HTLV-I/II seropositivity and death from AIDS among HIV-1 seropositive intravenous drug users. Lancet 1990; 335:1439-1441.
- Parks WP, Lenes BA, Tomasulo PA, Schiff ER, Parks ES, Shaw GM, Lee H, Yan HQ, Lai S, Hollingsworth CG. Human T-cell lymphtropic virus infection among blood donors in south Florida. The Transfusion Safety Study Group. J Acquir Immune Defic Syndr 1991; 4:89-96.
- Hutto C, Parks WP, Lai S, Mastrucci MT, Mitchell C, Munoz J, Trapido E, Master IM, Scott GB. A hospital-based prospective study of perinatal infection with human immunodeficiency virus type 1. J Pediatr 1991; 118:347-353.
- Chitwood DD, Page JB, Comerford M, Inciardi JA, McCoy CB, Trapido E, Lai S. The donation and sale of blood by intravenous drug users. Am J Public Health 1991; 81:631-633.
- Fischl MA, Daikos GL, Uttamchandani RB, Poblete RB, Moreno JN, Reyes RR, Boota AM, Thompson LM, Cleary TJ, Oldham SA, and Lai S. The clinical presentation and outcome of patients with tuberculosis caused by multiple drug resistant bacilli who have human immunodeficiency virus type I (HIV) infection. Ann Intern Med 1992; 117:184-190.
- Fischl MA, Uttamchandani RB, Daikos GL, Poblete RB, Moreno JN, Reyes RR, Boota AM, Thompson LM, Cleary TJ, Oldham SA, and Lai S. An outbreak of tuberculosis caused by multiple-drug-resistant tubercle bacilli among patients with HIV infection. Ann Intern Med 1992; 117:177-183.
- Gloeb DJ, Lai S, Efantis J and O'Sullivan MJ. Survival and disease progression in human immunodeficiency virus-infected women after an index delivery. Am J Obstet Gynecol 1992; 167:152-157.
- Geffin RB, Lai S, Hutto C, Scott GB, Scott WA, Master M. Parks WP. Quantitative analysis of human immunodeficiency virus type 1 antibody reactivity by western immunoblots: evaluation of relative antibody levels in seropositive individuals and mothers. J Infect Dis 1992; 165:111-118.
- Meng TC, Fischl MA, Boota AM, Spector SA, Bennet D, Bassiakos Y, Lai S, Wright B, Richman DD. Combination therapy with zidovudine and dideoxycytidine in patients with advanced human immunodeficiency virus infection. Ann Intern Med 1992; 116:13-20.
- Daikos GL, Lai S, Fischl MA. Hepatitis C virus infection in a sexually active inner city population. Infection 1994; 22(2); 72-76.
- Richman D., Meng Tze-Chiang, Spector S., Resnick L., Fischl M, Lai S. Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus. J Acquir Immune Defic Syndr 1994;7(2); 135-138.
- Metsch LR, McCoy CB, McCoy HV, Shultz JM, Lai S. HIV-related risk behaviors and seropositivity among homeless drug-abusing women in Miami, Florida. J Psychoactive Drugs 1995; 27:435-446.
- Engel A, Lamm SH and Lai S. Human breast sarcoma and human breast implantation: a time trend analysis based on SEER data. J Clin Epidemiol 1995; 48:539-544.
- Chitwood DD, Griffin DK, Comerford M, Page B, Trapido EJ, Lai S, and McCoy CB. HIV-1 risk factors among seroincident injection drug users: a case-control study. Am J Public Health 1995; 85:1538-1542.
- Gay CL, Armstrong FD, Cohen D, Scott GB, Lai S, Sanfilippo MD, Swales TP. The effects of HIV on cognitive and motor development in children born to seropositive women with no reported drug use history. Pediatrics 1995;96(6):1078-1082.
- Lorenzo E, Herrera RJ, Lai S, Fischl MA, Hill MD. The Tat and C2-V3 envelope genes in the molecular epidemiology of human immunodeficiency virus-1. Virology 1996; 221(2):310-312.
- Krongrad A, Lai H, Burke MA, Goodkin K, and Lai S: Marriage and mortality in prostate cancer. J Urol 1996; 156:1696-1700.
- Page JB, Lai S, Fletcher MA, Patarca R, Smith PC, Lai H, and Klimas NG. Predictors of survival in HIV-1 seropositive IDUs. Clin Diagn Lab Immunol 1996; 3:539-544.
- Krongrad A, Lai H, Lamm SH, and Lai S. Mortality in prostate cancer. J Urol 1996; 156:1084-1091.
- Byrd DM, Roegner ML, Griffiths JC, Lamm SH, Grumski KS, Wilson R, Lai S. Carcinogenic risks of inorganic arsenic in perspective. Int Arch Occup Environ Health 1996; 68:484-494.
- McCoy CB, Lai S, and Metsch LR, Wang X, Li C, Yang M, and Li Y. No pain, no gain: establishing the Kunming, China Drug Rehabilitation Center. J Drug Issues 1997; 4:73-85.
- Krongrad A, Granville LJ, Burke MA, Golden RM, Lai S, Cho L, and Niederberger CS. Predictors of general quality of life in patients with benign prostate hyperplasia or prostate cancer. J Urol 1997; 157:534-538.
- Krongrad A, Lai H, and Lai S. Survival after radical prostatectomy. JAMA 1997; 278:44-46.
- Savaraj N, Wu CJ, Xu R, Lampidis T, Lai S, Donnelly E, Solomon J, Feun LG. Multidrug-resistant gene expression in small-cell lung cancer. Am J Clin Oncol 1997; 20(4):398-403.
- Krongrad AK, Perczek RE, Burke MA, Granville LJ, Lai H, Lai S. Reliability of Spanish translations of selected urological quality of life instruments. J Urol 1997; 158:493-496.
- Krongrad AK, Lai H, Lai S. Competing risks of mortality in prostate cancer. J Urol 1997; 158:865-868.
- Krongrad AK, Lai H, and Lai S. Variation in prostate cancer survival explained by significant prognostic variables. J Urol 1997; 158:1487-1490.
- Baum MK, Shor-Posner G, Lai S, Zhang G, Lai H, Fletcher MA, Sauberlich H, and Page JB. High risk of mortality in HIV infection is associated with selenium deficiency. J Acquir Immune Defic Syndr 1997; 15:370-374.
- Krongrad A, Clark LC, Lai H, Soloway MS, and Lai S. Redistribution of age-specific prostate cancer stage at diagnosis. Dis Manage Clin Outcomes 1997; 1(2):41-46.
- Savaraj N, Xu R, Landy H, Lai S, Sternau L, Solomon J, Wu CJ, Lampidis T, Feun L. Comparison of topoisomerase I and II expression in primary brain tumor and lung cancer. Oncol Rep 1997; 4:857-861.
- Krongrad A, Lai H, and Lai S. Hospitalization, inpatient physical therapy, and post-discharge institutionalization in south Florida prostate cancer patients. J Urol 1997; 158:888-892.
- Krongrad A, Lai S, Vidal EM. The significance of changing trends in prostate cancer incidence and mortality. Semin Urol Oncol 1998; 16:30-34.
- Yu X-F, Chen J, Shao Y, Lai S. Two subtypes of HIV among injection-drug users in southern China. Lancet 1998; 351:1250.
- Krongrad A, Litwin MS, Lai H, and Lai S. Dimensions of quality of life in prostate cancer. J Urol 1998; 160:807-810.
- Metsch LR, McCoy CB, Lai S, Miles C. Continuing risk behaviors among HIV-positive chronic drug users in Miami, Florida. AIDS Behav 1998; 2(2):161-169.
- Krongrad A, Lai H, and Lai S. Disease-specific death after external beam radiation of prostate cancer. Prostate Cancer Prostatic Dis 1998; 1:144-147.
- Geffin RB, Scott GB, Melenwick M, Hutto C, Lai S, Boots LJ, McKenna PM, Kessler JA, Conley AJ. Association of antibody reactivity to ELDKWA, a gp41 neutralization epitope, with disease progression in children perinatally infected with HIV. AIDS Res Hum Retroviruses 1998; 14(7):579-590.
- McCoy HV, McCoy CB, and Lai S. Effectiveness of HIV intervention among women drug users. Women Health 1998; 27(1/2):49-66.
- Arango C, Rugeles MT, Concha M, Borrero I, H Lai, S Lai, Bernal C, Bernal E. Risk factors for HTLV-I mother to child transmission: influence of genetic markers. Braz J Infect Dis 1998; 2(3):135-142.
- Sharir T, Germano G, Kavanagh PB, Lai S, Cohen I, Lewin HC, Friedman JD, Zellweger MJ, Berman DS. Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography. Circulation 1999; 100(10):1035-1042.
- McCoy, CB, Metsch LR, McCoy HV, Lai S. A gender comparison of HIV and drug use across the rural-urban continuum. Popul Res Policy Rev 1999; 18:71-87.
- Obek C, Sadek S, Lai S, Civantos F, Soloway MS. Positive surgical margins with radical retropubic prostatectomy: anatomic site-specific pathological analysis and impact on prognosis. Urology 1999; 54(4):682-688.
- Obek C, Sadek S, Lai S, Civantos F, Soloway MS. Age as a prognostic factor for disease recurrence following radical prostatectomy. Urology 1999; 54(3):533-538.
- McCoy HV, McCoy CB, Lai S, Weatherby NL, Messiah S. Behavior changes among crack-using rural and urban women. Subst Use Misuse 1999; 34(4&5):667-684.
- Lai H, Lai S, Krongrad A, Trapido E, Page JB, McCoy CB. The effect of marital status on survival in late-stage cancer patients: an analysis based on surveillance, epidemiology, and end results (SEER) data, in the U.S. Int J Behav Med 1999;6(2):150-176.
- Yu XF, Chen J, Shao Y, Beyrer C, Liu B, Wang Z, Liu W, Yang J, Liang S, Viscidi RP, Gu J, Gurri-Glass G, Lai S. Emerging HIV infections with distinct subtypes of HIV-1 among injection drug users from geographically separated locations in Guangxi Province, China. J Acquir Immune Defic Syndr 1999; 22:180-188.
- Krongrad A, Lai S. The problems with neural networks in urology. Urology 1999; 54(6):949-951.
- Civantos F, Sadek S, Obek C, Lai S, Soloway M. Neoadjuvant hormonal therapy prior to radical prostatectomy. Mol Urol 1999; 3(3):201-204.
- Feun LG, Savaraj N, Hurley J, Marini A, Lai S. A clinical trial of intraveous navelbine (vinorelbine tartrate) plus tamoxifex in advanced malignant melanoma. Cancer 2000, 88:584-588.
- Lai S, Z Yang. Leaping subsequence algorithm in exact inference of contingency tables. Chinese J Math Appl (published by Allerton Press, Inc, in NY), 1999; 21(2):1-14.
- Lai S, Lai H, Krongrad A, Lamm S, Schwade J, Roos BA. Radical prostatectomy: geographic and demographic variation. Urology 2000; 56(1):108-115.
- Lai S, Lai H, Lamm S, Can Obek, Krongrad A, Roos BA. Radiation therapy in non-surgically-treated nonmetastatic prostate cancer: geographic and demographic variation. Urology 2001; 57:510-517.
- Lai S, Goldman JA, Engel A, Lamm SH. Fibromyalgia, hypermobility and breast implants. J Rheumatol 2000; 27:2237-2241.
- McCoy CB, McCoy HV, Lai S, Yu Z, Wang X, Meng J. Reawakening the dragon: changing patterns of opiate abuse in Asia, with particular emphasis on China’ Yunnan Province. Subst Use Misuse 2001; 36(1-2):49-69.
- Lai S, Chen J, Celentano D, Page JB, Lai H, Yang J, Liang S, McCoy CB, Yu X-F. Adoption of injection practices in heroin users in Guangxi province, China. J Psychoactive Drugs 2000; 32(3):285-292.
- Lai S, Lai H, Page JB, McCoy CB. The association between cigarette smoking and drug abuse in the United States. J Addict Dis 2000; 19(4):11-24.
- Lai S, H Lai, Krongrad A, Roos BA. Overall and disease-specific survival after radical prostatectomy: geographic uniformity. Urology 2001; 57:504-509.
- Lai S, Liu W, Chen J, Yang J, Li ZJ, Li RJ, Liang FX, Liang SL, Zhu QY, XF Yu. Changes in HIV-1 incidence in heroin users in Guangxi Province, China. J Acquir Immune Defic Syndr 2001; 26(4):365-370.
- Yu XF, Liu W, Chen J, Tian C, Yang J, Liang F, McCutchan F, Piyasirisilp S, Lai S. Rapid dissemination of a novel B/C recombinant HIV-1 among injection drug users in southern China. AIDS 2001; 15(4):523-525.
- Piyasirishlp S, McCutchan FE, Carr JK, Sanders-Buell E, Liu W, Chen J, Wagner R, Wolf H, Shao Y, Lai S, Beyrer C, Yu XF. A recent outbreak of human immunodeficiency virus type 1 infection in southern China was initiated by two highly homogeneous, geographically separated strains, circulating recombinant form AE and a novel BC recombinant. J Virol 2000; 74(23):11286-11295.
- Zellweger MJ, Lewin HC, Lai S, Dubois EA, Friedman JD, Germano G, Kang X, Sharir T, Berman DS. When to stress patients after coronary artery bypass surgery? Risk stratification in patients early and late post-CABG using stress myocardial perfusion SPECT: implications of appropriate clinical strategies. J Am Coll Cardiol 2001; 37(1):144-152.
- Lai H, Lai S, Shor-Posner G, Ma F, Trapido E, Baum MK. Plasma zinc, copper, copper/zinc ratio and survival in a cohort of HIV-1 infected homosexual men. J Acquir Immune Defic Syndr 2001; 27:56-62.
- Lai H, Lin L, Nadji M, Lai S, Trapido E and Meng L. Mutations in the p53 tumor suppressor gene and early onset breast cancer. Cancer Biol Ther 2002; 1(1), 31-36, discussion 37-38.
- Meng Q, Lai H, Tong W, Qian Y, Lai S. Echocardiographic and pathological characteristics of cardiac metastasis in patients with malignant lymphoma. Oncol Rep 2002; 9(1):85-88.
- Vlahov D, Safaien M, Lai S, Strathdee SA, Johnson L, Sterling T, Celentano DD. Sexual and drug risk-related behaviours after initiating highly active antiretroviral therapy among injection drug users. AIDS 2001; 15(17):2311-2316.
- Yu X-F, Liu W, Chen J, Kong W, Liu B, Zhu Q, Liang F, McCutchan F, Piyasirisilp S, Lai S. Maintaining low HIV type 1 env genetic diversity among injection drug users infected with a B/C recombinant and CRF01_AE HIV type 1 in southern China. AIDS Res Hum Retroviruses 2002; 18(2):167-170.
- Meng Q, Lai H, Lima J, Tong W, Qian Y, Lai S. Echocardiographic and pathologic characteristics of primary cardiac tumors: a study of 149 cases. Int J Cardiol 2002; 84(1); 69-75.
- Meng Q, Lima JAC, Lai H, Vlahov D, Celentano DD, Strathdee SA, Nelson KE, Wu KC, Chen S, Tong W, Lai S. Coronary artery calcification, atherogenic lipid changes and increased erythrocyte volume in HIV-1 infected participants treated with protease inhibitors. American Heart J 2002; 144(4):642-8.
- Meng Q, Lima JAC, Lai H, Vlahov D, Celentano DD, Strathdee S, Nelson KE, Tong W, Lai S. Use of HIV Protease Inhibitors Is Associated with Left Ventricular Morphologic Changes and Diastolic Dysfunction. J Acquir Immune Defic Syndr 2002; 30:306-310.
- Sauri M, Sibley C, Monk B, Nichols M and Lai S. Durability of vaccinia immunization based on reaction at the rechallenge site. Md Med Spring 2002; 3(2): 44-51.
- Lai S, Lai H, Meng Q, Tong W, Vlahov D, Celentano D, Strathdee S, Nelson K, Fishman EK, Lima JAC. Effect of cocaine use on coronary calcification among black adults in Baltimore. Am J Cardiol 2002; 90:326-328.
- Myerburg RJ, Fenster J, Velez M, Rosenberg D, Lai S, Kurlansky P, Newton S, Knox M, and Castellanos A. Impact of community-wide police car deployment of automated external defibrillators on survival from out-of-hospital cardiac arrest. Circulation 2002; 106:1058-1064.
- Zellweger MJ, Dubois EA, Lai S, Shaw LJ, Amanullah AM, Lewin HC, Friedman JD, Kang X, Germano G, Berman DS. Risk stratification in patients with remote prior myocardial infarction using rest-stress myocardial perfusion SPECT: Prognostic value and impact on referral to early catheterization. J Nucl Cardiol 2002; 9(1):23-32.
- Soldin OP, Nandedkar AK, Japal KM, Stein M, Mosee S, Magrab P, Lai S, Lamm SH. Newborn thyroxine levels and childhood ADHD. Clin Biochem 2002; 35(2):131-136.
- Meng Q, Lima JAC, Lai H, Vlahov D, Celentano DD, Margolick JB and Lai S. Elevated C- Reactive Protein Levels Are Associated With Endothelial Dysfunction in Chronic Cocaine Users. Int J Cardiol 2003; 88:191-198.
- Soldin OP, Lai S, Lamm SH. Lack of relationship between human neonatal thyroxine
and neurobehavioral disorders. Thyroid 2003; 13(2):193-198. - Lai S, Lai H, Celentano DD, Vlahov D, Ren S, Margolick J, Lima JAC, and Bartlett JG. Factors associated with Accelerated Atherosclerosis in HIV-1–infected Persons Treated with Protease Inhibitors. AIDS Patient Care STDS, 2003; 17(5):211-9.
- Lai H, Lai S, Ma F, Meng L and Trapido E. Prevalence and spectrum of p53 mutations in white Hispanic and non-Hispanic women with breast cancer. Breast Cancer Res Treat 2003; 81(1):53-60.
- Cole SR, Hernan MA, Robin JM, Anastos K, Chmiel J, Detels R, Ervin C, Feldman J, Greenblatt R, Kingsley L, Lai S, Young M, Cohen M, Munoz A. Effect of highly active antiretroviral therapies on time to AIDS or death using marginal structural models. Am J Epidemiol 2003; 158(7):687-94.
- Baum MK, Campa A, Lai S, Lai H, Page JB. Zinc Status in HIV-1 Infection and Drug Abuse. Clin Infect Dis 2003; 37 Suppl 2:S117-23.
- Robles C, Furst AJ, Sriratana P, Lai S, Chua L, Donnelly E, Solomon J, Sundaram M, Feun L, Savaraj N. Phase II study of vinorelbine with low dose prednisone in the treatment of hormone-refractory metastatic prostate cancer. Oncol Rep. 2003; 10(4):885-9.
- Yu X, Wang X, Mao P, Wang S, Li Z, Zhang J, Garten R, Kong W, Lai S. Characterization of HIV-1 heterosexual transmission in Yunnan, China. AIDS Res Hum Retroviruses 2003; 19(11): 1051-5.
- Chang S, Crothers C, Lai S, Lamm S. Pediatric neurobehavioral diseases in Nevada counties with respect to perchlorate in drinking water: an ecological inquiry. Birth Defects Res Part A Clin Mol Teratol 2003; 67(10):886-92.
- Breen EC, Boscardin WJ, Detels R, Jacobson LP, Smith MW, O'Brien SJ, Chmiel JS,
Rinaldo CR, Lai S, and Martínez-Maza O. Non-Hodgkin's B cell lymphoma in persons with acquired immunodeficiency syndrome is preceded by increased serum levels of IL10, and is associated with a high IL10-expressing genotype. Clin Immunol 2003; 109(2):119-29. - Alegria M, Canino G, Lai S, Ramirez RR, Chavez L, Rusch D. Understanding caregiver’s help-seeking for Latino children’s mental health care use. Med Care 2004;42(5):447-455.
- Lai H, Ma F, Trapido E, Meng L, Lai S. Spectrum of p53 tumor suppressor gene mutations and breast cancer survival. Breast Cancer Res Treat 2004;83(1):57-66.
- Tong W, Lima JAC, Lai H, Celentano DD, Dai S, and Lai S. Relation of coronary artery calcium to left ventricular mass in African Americans. Am J Cardiol 2004; 93:490-492.
- McCoy C, Lai S, Metsch LR, Messiah SE, Zhao W. Injection Drug Use and Crack Cocaine Smoking: Independent and Dual Risk Behaviors for HIV Infection. Ann Epidemiol 2004;14(8):535-42.
- Lamm SH, Byrd DM, Kruse MB, Feinleib M, Lai S. Bladder cancer and arsenic exposure: differences in the two populations enrolled in a study in southwest Taiwan. Biomed Environ Sci 2003; 16:355-368.
- Lamm SH, Engel A, Kruse MB, Feinleib M, Byrd DM, Lai S, Wilson R. Arsenic in drinking water and bladder cancer mortality in the United States: an analysis based on 133 U.S. counties and 30 years of observation. J Occup Med 2004;46(3):298-306.
- Laeyendecker O, Zhang, GW, Quinn TC, Garten R, Ray SC, Lai S, Liu W, Yu X-F. Molecular epidemiology of HIV-1 subtypes in southern China. J Acquir Immune Defic Syndr 2005;38(3):356-362.
- Garten RJ, Lai S, Zhang J, Liu W, Chen J, Vlahov D, Yu XF. Rapid transmission of hepatitis C virus among young injecting heroin users in Southern China. Int J Epidemiol 2004;33(1):182-8.
- Alegria M, Vera M, Shrout P, Canino G, Lai S, Albizu C, Marin H, Pena M, Rusch D. Understanding hard-core drug use among urban Puerto Rican women in high-risk neighborhoods. Addict Behav 2004;29(4):643-64.
- Tong W, Lima JA, Meng Q, Flynn E, Lai S. Long-term cocaine use and cardiac diastolic dysfunction: an echocardiographic study. Int J Cardiol 2004;97:25-28.
- Tong W, Lai H, Yang C, Ren S, Dai S, Lai S. Age, gender and metabolic syndrome-related coronary heart disease in US adults. Int J Cardiol 2005; Oct 10;104(3):288-291.
- JA, Desai MY, Steen H, Warren WP, Gautam S, Lai S. Statin-induced cholesterol lowering and plaque regression after 6 months of magnetic resonance imaging-monitoring therapy. Circulation 2004; 110(16):2336-41.
- Hansen H, Alegria M, Caban CA, Pena M, Lai S, Shrout P.Drug treatment, health, and social service utilization by substance abusing women from a community-based sample. Med Care. 2004 Nov;42(11):1117-24.
- Lai, S, Lima JAC, Lai H, Vlahov D, Celentano D, Tong W, Bartlett JG, Margolick JH, Fishman EK. HIV-1 Infection, Cocaine, and Coronary Calcification. Arch Intern Med 2005;165: 690-695.
- Garten R, Lai S, Liu W, Chen J and Yu XF. HIV/HCV co-infection among injection drug users in southern China. Inf. Dis 2005 Jul 1;41 Suppl 1:S18-24..
- Levis S, Gomez A, Jimenez C, Veras L, Ma F, Lai S, Hollis B, Roos BA. Vitamin D deficiency and seasonal variation in an adult south Florida population. J Clin Endocrinol Metab 2005;90(3):1557-62.
- Steen H, Warren WP, Desai M, Gautam S, Lai S, Heath S, Stuber M, Lima JA. Combined transesophageal and surface MRI provides optimal imaging in aortic atherosclerosis. J Cardiovasc Magn Reson. 2004;6(4):909-16.
- Signorile JF, Carmel MP, Lai S, Roos BA. Early Plateaus of Power and Torque Gains during High-Speed and Low-Speed Resistance Training of Older Women. J Appl Physiol. 2005 Apr; 98(4):1213-20.
- Ma F, Fleming LE, Lee DJ, Trapido E, Gerace TA, Lai H, Lai S. Mortality in Florida professional firefighters, 1972 to 1999. Am J Ind Med 2005 Jun; 47(6):509-17.
- Hou X, Lai S, Lai H. A spectral analysis to stabilization of a flexible beam with structural damping. International Journal of Pure and Applied Mathematics 2005.
- Natori S, Lai S, Ren S, Finn JP, Gomes AS, Hundley GW, Jerosch-Herold M, Pearson G, Sinha S, Olson J, Arai A, Lima JAC, Bluemke DA. Cardiovascular function in multi-ethnic studyof atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol. 2006 Jun;186(6 Suppl 2):S357-65.
- Meng QY, DU JF, Lai H, Lai SH. Coronary artery calcification is associated with atherogenic lipid changes, cardiac dysfunction and morphologic abnormalities in HIV-1 infected black adults. Chin Med J (Engl). 2005;118(5):412-4.
- Rosen BD, Edvardsen T, Lai S, Castillo E, Pan L, Jerosch-Herold M, Shantanu S, KronmalR, Arnett D, Crouse III JR, Heckbert SR, Bluemke DA, Lima JAC. Left ventricular concentric remodeling is associated with decreased global and regional systolic function: the Multi-Ethnic Study of Atherosclerosis. Circulation 2005; 112(7):984-91.
- Desai MY, Lai S, Barmet C, Weiss RG, Stuber M. Reproducibility of improved 3Dfree-breaching magnetic resonance coronary vessel wall imaging. Eur Heart J 2005; Jun 21; 26:2320-4.
- Ren S, Tong W, Lai H, Osman NF, Pannu H, Lai S. Effect of long-term cocaine use on regional left ventricular function as determined by magnetic resonance imaging. Am J Cardiol.2006;97:1085-8.
- Qian HZ, Yang Z, Shi X, Gao J, Xu C, Wang L, Zhou K, Cui Y, Zheng X, Wu Z, Lu F, Lai S, Vermund SH, Shao Y, Wang N. Hepatitis C virus infection in former commercial plasma/blood donors in rural shanxi province, china: the china integrated programs for research on AIDS. J Infect Dis. 2005 Nov 15;192(10):1694-700.
- Campa A, Yang Z, Lai S, Xue L, Phillips JC, Sales S, Page JB, Baum MK. HIV-related wasting in HIV-infected drug users in the era of highly active antiretroviral therapy. Clin Infect Dis. 2005 Oct 15;41(8):1179-85.
- Edvardsen T, Detrano R, Rosen BD, Carr JJ, Liu K, Lai S, Shea S, Pan L, Bluemke DA, Lima JA. Coronary Artery Atherosclerosis Is Related to Reduced Regional Left Ventricular Function in Individuals Without History of Clinical Cardiovascular Disease. The Multiethnic Study of Atherosclerosis Study. Arterioscler Thromb Vasc Biol. 2006;26:206-11.
- Castillo E, Osman NF, Rosen BD, El-Shehaby I, Pan L, Jerosch-Herold M, Lai S, Bluemke DA, Lima JOA. Quantitative assessment of regional myocardial function with MR-tagging in a multi-center study: interobserver and intraobserver agreement of fast strain analysis with Harmonic Phase (HARP) MRI. J Cardiovasc Magn Reson. 2005;7: 783–791.
- Edvardsen T, Rosen BD, Pan L, Jerosch-Herold M, Lai S, Hundley WG, Sinha S, Kronmal RA, Bluemke DA, Lima JA. Regional diastolic dysfunction in individuals with left ventricular hypertrophy measured by tagged magnetic resonance imaging--the Multi-Ethnic Study of Atherosclerosis (MESA). Am Heart J. 2006 Jan;151(1):109-14.
- Ren S, Yang S, Lai S. Intraclass Correlation Coefficients and Bootstrap Methods of Hierarchical Binary Outcomes. Stat Med 2006 Oct 30;25(20): 3576-88.
- Dickfeld T, Kato R, Zviman M, Lai S, Meininger G, Lardo AC, Roguin A, Blumke D, Berger R, Calkins H, Halperin H. Characterization of radiofrequency ablation lesions with gadolinium-enhanced cardiovascular magnetic resonance imaging. J Am Coll Cardiol. 2006 Jan 17;47(2):370-8.
- Dong J, Calkins H, Solomon SB, Lai S, Dalal D, Lardo A, Brem E, Preiss A, Berger RD, Halperin H, Dickfeld T. Integrated electroanatomic mapping with three-dimensional computed tomographic images for real-time guided ablations. Circulation 2006 Jan 17;113(2):186-94.
- Margolick JB, Gange SJ, Detels R, O’Gorman MRG, Rinaldo CR, Jr., Lai S.Impact of inversion of the CD4/CD8 ratio on the natural history of HIV-1 infection. J Acquir Immune Defic Syndr. 2006 Aug 15;42(5):620-626.
- Liu W, Chen J, Rodolph M, Beauchamp G, Mâsse B, Wang S, Li R, Ruan Y, Zhou F, Leung, M-K, Lai S, Shao Y, Jackson JB. HIV prevalence among injection drug users in rural Guangxi, China. Addiction 2006 Oct;101(10):1493-8.
- Rosen BD, Saad MF, Shea S, Nasir K, Edvardsen T, Burke G, Jerosch-Herold M, Arnett DK, Lai S, Bluemke DA, Lima JA. Hypertension and smoking are associated with reduced regional left ventricular function in asymptomatic: individuals the Multi-Ethnic Study of Atherosclerosis. J Am Coll Cardiol. 2006 Mar 21;47(6):1150-8.
- Pannu HK, Jacobs JE, Lai S, Fishman EK. Gated cardiac imaging of the aortic valve on 64-slice multidetector row computed tomography: preliminary observations. J Comput Assist Tomogr 2006 May/June; 30(3):443-446.
- Pannu HK, Jacobs JE, Lai S, Fishman EK. Coronary CT angiography with 64-MDCT: assessment of vessel visibility. AJR Am J Roentgenol. 2006 Jul;187(1):119-26.
- Rosen BD, Lima JA, Nasir K, Edvardsen T, Folsom AR, Lai S, Bluemke DA, Jerosch-Herold M.Lower Myocardial Perfusion Reserve Is Associated With Decreased Regional Left Ventricular Function in Asymptomatic Participants of the Multi-Ethnic Study of Atherosclerosis. Circulation. 2006 Jul 25;114(4):189-97.
- Wei L, Chen J, Rodolph M, Beauchamp G, M 0226 Sse B, Li R, Wang S, Ruan Y, Lai S, Zhang L, Zhou F, Rose SM, Perdue T, Lai S, Shao Y, Jackson JB. HIV Incidence, Retention, and Changes of High-Risk Behaviors Among Rural Injection Drug Users in Guangxi, China. Subst Abus. 2006;27(4):53-61.
- Baum MK, Rafie C, Lai S, Xue L, Sales S, Page JB, Berkman R, Karas L, Campa A. Coronary Heart Disease (CHD) Risk Factors and Metabolic Syndrome in HIV-Positive Drug Users in Miami. Am J Infect Dis. 2006;2(3):173-179. PMCID: PMC2435190.
- Rosen BD, Cushman M, Nasir K, Bluemke DA, Edvardsen T, Fernandes V, Lai S, Tracy RP, Lima JA. Relationship between C-reactive protein levels and regional left ventricular function in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis. J Am Coll Cardiol. 2007 Feb 6;49(5):594-600.
- Pannu HK, Sullivan C, Lai S, Fishman EK. Evaluation of the effectiveness of oral beta blockade in patients for coronary CT angiography. J Comput Assist Tomogr 2008 Mar-Apr;32(2):247-51.
- Yin L, Qin GM, Ruan YH, Qian H-Z, Hao C, Xie LZ, Chen K, Zhang YF, Xia YW, Wu JL, Lai S, Shao Y. Nonfatal overdose among heroin users in southwestern China. Amer J Drug Alcohol Abuse 2007; 33:505-16.
- Lamm SH, Luo Z-D, Bo F-B, Zhang G-Y, Zhang Y-M, Wilson R, Byrd DM, Lai S, Li F-X, Polkanov M, Tong Y, Loo L, Tucker SB, and the Inner Mongolia Cooperative Arsenic Project (IMCAP). An Epidemiologic Study of Arsenic-Related Skin Disorders and Skin Cancer and the Consumption of Arsenic-Contaminated Well Waters in Huhhot, Inner Mongolia, China, Human and Ecological Risk Assessment 2007;13: 1–34.
- Steen H, Nasir K, Flynn E, El-Shehaby I, Lai S, Katus HA, Bluemcke D, Lima JA. Is magneticresonance imaging the 'reference standard' for cardiac functional assessment? factors influencing measurement of left ventricular mass and volumes. Clin Res Cardiol. 2007 Oct;96(10):743-51.
- Tetsuo Sasano, Kan Kikuchi, Amy D. McDonald, Shenghan Lai, and J. Kevin Donahue.Targeted High-Efficiency, Homogeneous Myocardial Gene Transfer. J Mol Cell Cardiol. 2007 May; 42(5): 954–961. PMCID: PMC1976378
- Lai S, Fishman EK, Lai H, Moore R, Cofrancesco J, Pannu H, Tong W, Du J, Bartlett J. Long- term cocaine use and antiretroviral therapy are associated with silent coronary artery disease in cardiovascularly asymptomatic African Americans with HIV infection. Clin Infect Dis; 2008; 46:600-610.
- Baum MK, Jayaweera DT, Duan R, Sales S, Lai S, Rafie C, Page JB, Campa A. Quality of life, symptomatology, and healthcare utilization in HIV/HCV co-infected drug users in Miami. J Addict Dis 2008;27(2):37-48.
- Zeng H, Tso M, Lai S, Lai H. Activation of nuclear factor-κB in the retinal degeneration. Mol Vis 2008;14:1075-80.
- Wasserman BA, Sharrett AR, Lai S, Gomes AS, Cushman M, Folsom AR, Bild DE, Kronmal RA, Sinha S, Bluemke DA. Risk Factor Associations with the Presence of a Lipid Core in Carotid Plaque of Asymptomatic Individuals Using High-Resolution MRI. The Multi-Ethnic Study of Atherosclerosis (MESA). Stroke. 2008 Feb;39(2):329-35.
- Ren S, Chu H, Lai S. Sample size and power calculations for left-truncated normal distribution. Communications in Statistics – Theory and Methods 2008;37:1-14.
- Wu KC, Weiss RG, Thiemann DR, Kitagawa K, Schmidt A, Dalal D, Lai S, Bluemke DA, GerstenblithG, Marban E, Tomaselli GF, Lima JAC. Late Gadolinium enhancement by cardiovascular magnetic resonance heralds an adverse prognosis in nonischemic cardiomyopathy. J Am Coll Cardiol 2008 June24;51(25):2414-21.
- Garten RJ, Lai SH, Zhang JB, Liu W, Chen J, Yu XF. Garten RJ, Lai SH, Zhang JB, Liu W, Chen J, Yu XF. Factors influencing a low rate of hepatitis C viral RNA clearance in heroin users from Southern China. World J Gastroenterol. 2008 Mar 28;14(12):1878-84.
- Baum MK, Rafie C, Lai S, Duan S, Jayaweera DT, Page JB, Campa A. C-reactive protein: a poor marker of cardiovascular disease risk in HIV+ populations with high prevalence of elevated serum transaminases. Int J STD AIDS 2008;19:410-413.
- Korosoglou G, Youssef AA, Bilchick KC, Ibrahim el-S, Lardo AC, Lai S, Osman NF. Real-Time fast strain-encoded magnetic resonance imaging to evaluate regional myocardial function at 3.0 Tesla: comparison to conventional tagging. J Magn Reson Imaging. 2008 May;27(5):1012-8.
- Leung IYF, Lai S, Ren S, Kempen J, Klein R, Tso MOM, Lai H. Early retinal vascular abnormalities in African-American cocaine users. Am J Ophthalmol. 2008. Oct;146(4):612-619.
- Ngo TD, Laeyendecker O, Morrow RA, Lai S, Quinn TC. Performance of Focus, Kalon, and Biokit for the Detection of Herpes Simplex Virus Type 2- Antibodies among Commercial Sex Workers in Yunnan Province, China. Clin Vaccine Immunol. 2008 May 28. [Epub ahead of print]
- Macedo R, Chen S, Lai S, Shea S, Malayeri AA, Szklo M, Lima JA, Bluemke D. MRI detects Increased coronary wall thickness in asymptomatic individuals: The Multi-Ethnic Study of Atherosclerosis (MESA). J Magn Reson Imaging. 2008 Oct 3. [Epub ahead of print].
- Lai S, Fishman EK, Lai H, Pannu H, Detrick B. Serum IL-6 Levels are Associated with Significant Coronary Stenosis in Cardiovascularly Asymptomatic Inner-City Black Adults in the US. Inflamm Res 2009 Jan;58(1):15-21.
- Perez-Rodriguez J, Lai S, Ehst B, Fine D, Bluemke DA. A Report of 33 cases of nephrogenic systemic fibrosis: incidence, associations and impact of risk factor assessment. Radiology 2009 Feb;250(2):371-7.
- Miao C, Chen S, Macedo R, Lai S, Liu K, Li D, Wasserman B,Vogel-Clausen J, Lima JAC, Bluemke DA. Positive remodeling of the coronary arteries detected by MRI in an asymptomatic population: the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol. 2009 May 5;53(18):1708-15.
- Baum MK, Rafie C, Lai S, Sales S, Page B, Campa A. Crack-cocaine use accelerates HIV disease progression in a cohort of HIV-positive drug users. J Acquir Immune Defic Syndr. 2009 Jan 1;50(1):93-9.
- Malayeri AA, Macedo R, Li D, Chen S, Bahrami H, Lai S, Lima JA, Bluemke DA.Coronary vessel wall evaluation by magnetic resonance imaging in the multi-ethnic study of atherosclerosis: determinants of image quality. J Comput Assist Tomogr. 2009 Jan-Feb;33(1):1-7.
- Lai H, Zeng HY ; Zhang C; Wang L; Tso M; Lai S. Toxic Effect of Methamphetamine on the Retina of CD1 Mice. Curr Eye Res 2009 Sep;34(9):785-90.
- Stanziano DC, Roos BA, Perry AC, Lai S, Signorile JF. The effects of an active-assisted program on functional performance in elderly persons: A pilot study. Clin Interv Aging 2009; 4(1): 115-
- Lai S, Bartlett J, Lai H, Moore R, Cofrancesco J, Pannu H, Tong W, Gao PJ, Meng W, Sun H, Fishman EK. Long-term Combination Antiretroviral Therapy Is Associated with the Risk of Coronary Plaques in African Americans with HIV Infection. AIDS Patient Care STDs 2009 Oct; 23(10):815-24.
- Delaney JA, McClelland RL, Brown E, Bluemke DA, Vogel-Claussen J, Lai S, Heckbert SR. Multiple imputation for missing with cardiac magnetic resonance imaging data: Results from the Multi-Ethnic Study of Atherosclerosis (MESA). Can J Cardiol 2009 July ;25(7):e232-5.
- Lai H, Redheuil A, Tong W, Bluemke DA, Lima JAC, Ren S, Lai S. HIV infection and abnormal ventricular function. Int J Cardiovasc Imaging 2009 Dec; 25(8):809-17.
- Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR, Lardo AC, Lai S, Steenbergen C, Gerstenblith G, Lange R, Marbán E. Engraftment, Differentiation, and Functional Benefits of Autologous Cardiosphere-Derived cells in Porcine Ischemic Cardiomyopathy. Circulation 2009 Sep 22;120(12):1075-83.
- Baum MK, Lai S, Sales S, Page B, Campa A. Randomized Controlled Clinical Trial of Zinc Supplementation to Prevent Immunological Failure in HIV-Positive Adults. Clin Infect Dis 2010 Jun 15;50(12): 1653-60.
- Sachdev M, Fetics BJ, Lai S, Dalal D, Insel J, Berger RD. Failure in short-term prediction of ventricular tachycardia and ventricular fibrillation from continuous electrocardiogram in intensive care unit patients.J Electrocardiol. 2010 Sep-Oct; 43(5):400-7.
- Baum MK, Rafie C, Lai S, Sales S, Page JB, Campa A. Alcohol use accelerates HIV disease progression. AIDS Res Hum Retroviruses. 2010 May;26(5):511-8.
- Baum MK, Sales S, Jayaweera DT, Lai S, Bradwin G, Rafie C, Page JB, Campa A. Coinfection with hepatitis C virus, oxidative stress and antioxidant status in HIV-positive drug users in Miami. HIV Med. 2011 Feb;12(2):78-86.
- Ren S, Lai H, Tong W, Aminzadeh M, Hou X, Lai S. Nonparametric bootstrapping for hierarchical data. J Appl Stat 2010 September; 37(9): 1487-1498.
- Lai H, Fishman E, Gerstenblith G, Brinker J, Tong W, Bhatia S, Detrick B, Lai S. Vitamin D Deficiency Is Associated with Significant Coronary Stenoses in Asymptomatic African American Chronic Cocaine Users. Int J Cardiol 2012 Jul 12;158(2):211-6.
- Reinier K, Dervan C, Singh T, Uy-Evanado A, Lai S, Gunson K, Jui J, Chugh SS. Independent effects of left ventricular mass and systolic function on sudden death in the coronary artery disease. Heart Rhythm 2011 Aug 8(8):1177-82.
- Krongrad A, Lai S. Laparoscopic Prostatectomy for Severely Symptomatic, Treatment-Refractory, Chronic Prostatitis: Preliminary Observations from an Ongoing Phase II Clinical Trial. Urotoday Int J 2011 Apr;4(2): Art30. doi:10.3834/uij.1944-5784.2011.04.12
- Tai H, Lai H, Jani J, Lai S, Kickler TS. HIV Infection and Cocaine Use Induce Endothelial Damage and Dysfunction in Africa Americans. Int J Cardiol 2012 Nov 15;161(2):83-7.
- Miao C, Chen S, Ding J, Liu K, Li D, Macedo R, Lai S, Vogel-Claussen J, Brown E, Lima JAC, Bluemke DA. The Association of pericardial fat with coronary artery plaque by magnetic resonance imaging: the Multi-Ethnic Study of Atherosclerosis (MESA). Radiology Oct;261:109-15.
- Ning G, Bi Y, Wang T, Xu M, Xu Y, Huang Y, Li X, Wang W, Chen Y, Wu Y, Hou J, Song A, Liu Y, Li M, Lai S. Relationship of Urinary Bisphenol A Concentrations to Risk of Type 2 Diabetes in Chinese Adults. Ann Intern Med 2011 Sep 20;155(6):368-74.
- Dong R, Qiao X, Jia W, Wong M, Qian H, Zheng X, Xing W, Lai S, Wu Z, Jiang Y, Wang N. HIV, HCV, and HBV Co-Infections in a Rural Area of Shanxi Province with a History of Commercial Blood Donation. Biomed Environ Sci. 2011 Jun;24(3):207-13.
- Du J, Wasserman BA, Chen S, Tong W, Lai S, Saurabh M, Lai H. Cholesterol Is Associated with the Presence of a Lipid Core in Carotid Plaque of Asymptomatic, Young-to-Middle-aged African Americans with and without HIV Infection and Cocaine Use Residing in Inner-city Baltimore, Maryland. Cerebrovasc Dis. 2012 Feb 8;33(3):295-301.
- Wang T, Li M, Chen B, Xu M, Xu Y, Huang Y, Lu J, Chen Y, Wang W, Li X, Liu Y, Lai S, Ning G. Urinary Bisphenol A (BPA) Concentration Associates with Obesity and Insulin Resistance. Clin Endocrinol Metab. 2012 Feb;97(2):E223-7.
- Lai H, Detrick B, Fishman EK, Hollis BW, Gerstenblith G, Brinker JA, Bartlett J Cofrancesco J, Tong W, Tai H, Chen S, Bhatia S, Lai S. Vitamin D Deficiency is Associated with the Development of Subclinical Coronary Artery Disease in African Americans with HIV Infection: A Preliminary Study. J Investig Med 2012 Jun;60(5):801-807.
- Gupta A, Akki A, Wang Y, Leppo MK, Chacko VP, Foster DB, Caceres V, Shi S, Kirk JA, Su J, Lai S, Paolocci N, Steenbergen C, Gerstenblith G, Weiss RG. Creatine kinase-mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved. J Clin Invest. 2012 Jan 3;122(1):291-302. doi: 10.1172/JCI57426.
- Lai H, Gerstenblith G, Fishman EK, Brinker J, Kickler T, Tong W, Bhatia S, Tai H, Chen S, Li J, Detrick B, Lai S. Vitamin D Deficiency is Associated with Silent Coronary Artery Disease in Cardiovascularly Asymptomatic African Americans with HIV Infection. Clin Infect Dis 2012 Jun;54(12):1747-55.
- Venkatesh BA, Lima JAC, Bluemke DA, Lai S, Steenbergen C, Liu CY. MR proton spectroscopy for myocardial lipid deposition quantification: a quantitative comparison between 1.5-T and 3-T. J Magn Reson Imaging. 2012 Jul 23. doi: 10.1002/jmri.23761. [Epub ahead of print] PMID:22826193.
- Ning G, Mu Y, Liu C, Tong N, Bi Y, Li D, Lai S, Bloomgarden Risk Evaluation of cAncers in Chinese diabeTic Individuals: a lONgitudinal (REACTION) study. J Diabetes 2012;4(2):172-3.
- Hong J, Zhang Y, Lai S, Lv A, Su Q, Dong Y, Zhou Z, Tang W, Zhao J, Cui L, Zou D, Wang D, Li H, Liu C, Wu G, Shen J, Zhu D, Wang W, Shen W, Ning G. Effects of Metformin versus Glipizide on Cardiovascular Outcomes in Patients with Type 2 Diabetes and Coronary Artery Disease. Diabetes Care 2013 May;36(5):1304-11.
- Chen G, Xu Y, Lin Y, Lai X, Yao J, Huang B, Chen Z, Huang H, Fu X, Lin L, Lai S, Wen J. Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk, diabetic nephropathy in the Chinese She population. J Diabetes. 2013 2013 Jun;5(2):136-45.
- Wang T, Lu J, Xu M, Xu Y, Li M, Liu Y, Tian X, Chen Y, Dai M, Wang W, Lai S, Bi Y, Ning G. Urinary Bisphenol A Concentration and Thyroid Function in Chinese Adults. Epidemiology. 2013 Mar;24(2):295-302.
- Xu Y, Bi Y, Li M, Wang T, Sun K, Xu M, Lu J, Yu Y, Li X, Lai S, Wang W, Ning G. Significant Coronary Stenosis in Asymptomatic Chinese With Different Glycemic Status. Diabetes Care 2013 Jun;36(6):1687-94.
- Lai S, Fishman EK, Gerstenblith G, Brinker B, Hong T, Chen S, Li J, Tong W, Detrick B, Lai H. Vitamin D deficiency is associated with coronary artery calcification in cardiovascularly asymptomatic African Americans with HIV infection. Vasc Health Risk Manag 2013;9:493-500. doi: 10.2147/VHRM.S48388. Epub 2013 Aug 26.
- Lai H, Fishman EK, Gerstenblith G, Moore R, Brinker JA, Keruly JC, Chen S, Detrick B, Lai S. Vitamin D Deficiency is Associated with the Development of Subclinical Coronary Artery Disease in HIV-infected African American Cocaine Users with Low Framingham-defined CAD Risk. Vasc Health Risk Manag 2013;9:729-37. doi: 10.2147/VHRM.S50537. Epub 2013 Nov 15.
- Xu Y, Wang L, He J, Bi Y, Li M, Wang T, Wang L, Jiang Y, Dai M, Lu J, Xu M, Li Y, Hu N, Li J, Mi S, Chen CS, Li G, Mu Y, Zhao J, Kong L, Chen J, Lai S, Wang W, Zhao W, Ning G; 2010 China Noncommunicable Disease Surveillance Group. Prevalence and control of diabetes in Chinese adults.JAMA. 2013 Sep 4;310(9):948-59. doi: 10.1001/jama.2013.168118.
- Baum MK, Campa A, Lai S, Martinez SS, Tsalaile L, Burns P, Farahani M, Li Y, vanWidenfelt E, Page JB, Bussmann H, Fawzi WW, Moyo S, Makhema J, Thior I, Essex M, Marlink R, the Dikotlana Study Team. Effect of Micronutrient Supplementation on Disease Progression in Asymptomatic, Antiretroviral-Naïve, HIV-Infected Adults in Botswana: A Randomized Controlled Trial. JAMA 2013 Nov 27;310(20):2154-63.
- Bi Y, Lu J, Wang W, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Wan Q, Wu S, Yang T, Yan L, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Zhang J, Sun J, Dai M, Xu M, Xu Y, Chen Y, Lai S, Bloomgarden ZT, Li D, Ning G. Cohort Profile: Risk evaluation of cancers in Chinese diabetic Individuals: a longitudinal (REACTION) study. J Diabetes. 2013 Nov 14. doi: 10.1111/1753-0407.12108. [Epub ahead of print].
- Bottomley PA, Panjrath GS, Lai S, Hirsch GA, Wu K, Najjar SS, Steinberg A, Gerstenblith G, Weiss RG. Metabolic Rates of ATP Transfer through Creatine Kinase (CK flux) Predict Clinical Heart Failure Events and Death. Sci Transl Med. 2013 Dec 11;5(215):215re3. doi: 10.1126/scitranslmed.3007328.
- Parsons M, Campa A, Lai S, Li Y, Martinez JD, Murillo J, Greer P, Martinez SS, Baum MK. Effect of GSTM1-Polymorphism on Disease Progression and Oxidative Stress in HIV Infection: Modulation by HIV/HCV Co-Infection and Alcohol Consumption. J AIDS Clin Res. 2013 Aug 31;4(9). pii: 10002337.
- Liu C-Y, Bluemke D, Gerstenblith G, Zimmerman S, Li J, Zhu H, Lai S, Lai H. Myocardial Steatosis and Its Association with Obesity and Regional Ventricular Dysfunction: Evaluated by Magnetic Resonance Tagging and 1H Spectroscopy in Healthy African Americans. Int J Cardiol 2014 Mar 15;172(2):381-7. doi: 10.1016/j.ijcard.2014.01.074. Epub 2014 Jan 24.
- Liu J, Bi Y, Wang T, Wang W, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Wan Q, Wu S, Qin G, Yang T, Yan L, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Wang Y, Deng H, Yu X, Shen F, Chen L, Zhao L, Dai M, Xu M, Xu Y, Chen Y, Lai S, Ning G. The relationship between insulin-sensitive obesity and cardiovascular diseases in a Chinese population: Results of the REACTION study. Int J Cardiol 2014 Mar 15;172(2):388-94. doi: 10.1016/j.ijcard.2014.01.073. Epub 2014 Jan 25.
- Zhu M, Cai J, Liu S, Huang M, Chen Y, Lai X, Chen Y, Zhao Z, Wu F, Wu D, Miu H, Lai S, Chen G. Relationship between gestational fasting plasma glucose and neonatal birth weight, prenatal blood pressure and dystocia in pregnant Chinese women. Diabetes Metab Res Rev. 2014 Sep;30(6):489-96.
- Schuhbaeck A, Dey D, Otaki Y, Slomka P, Kral B, Achenbach S, Berman DS, Fishman E, Lai S, Lai H. Interscan Reproducibility of Quantitative Coronary Plaque Volume and Composition from CT Coronary Angiography using an Automated Method. Eur Radiol 2014 Sep; 24(9):2300-8.
- Yi CJ, Yang E, Lai S, Gai N, Liu C, Liu S, Zimmerman SL, Lima JA, Bluemke DA. Progression of diffuse myocardial fibrosis assessed by cardiac magnetic resonance T1 Int J Cardiovasc Imaging. 2014 Oct;30(7):1339-46.
- Liu CY, Bluemke DA, Gerstenblith G, Zimmerman SL, Li J, Zhu H, Lai S, Lai H. Reference Values of Myocardial Structure, Function and Tissue Composition by Cardiac Magnetic Resonance in Healthy African Americans at 3T and their Relations to Serologic and Cardiovascular Risk Factors. Am J Cardiol 2014 Sep1;114(5): 789-95.
- Zhang Y, Hu C, Hong J, Zeng J, Lai S, Lv A, Su Q, Dong Y, Zhou Z, Tang W, Zhao J, Cui L, Zou D, Wang D, Li H, Liu C, Wu G, Shen J, Zhu D, Wang W, Shen W, Ning G, Xu G. Lipid Profiling Reveals Different Therapeutic Effects of Metformin and Glipizide in Patients With Type 2 Diabetes and Coronary Artery Disease. Diabetes Care. 2014 Oct;37(10):2804-12. doi: 10.2337/dc14-0090. Epub 2014 Jul 10.
- Lai S, Gerstenblith G, Li J, Zhu H, Bluemke DA, Liu C-Y, Zimmerman SL, Chen S, Lai H, Treisman G. Chronic Cocaine Use and Its Association with Myocardial Steatosis Evaluated by 1H Magnetic Resonance Spectroscopy in African Americans. J Addict Med 2015 Jan-Feb 9(1):31-9.
- Sun JC, Xu M, Lu JL, Bi YF, Mu YM, Zhao JJ, Liu C, Chen LL, Shi LX, Li Q, Yang T, Yan L, Wan Q, Wu SL, Liu Y, Wang GX, Luo ZJ, Tang XL, Chen G, Huo YN, Gao ZN, Su Q, Ye Z, Wang YM, Qin GJ, Deng HC, Yu XF, Shen FX, Chen L, Zhao LB, Wang TG, Lai SH, Li DH, Wang WQ, Ning G; The Risk Evaluation of Cancers in Chinese Diabetic Individuals: A Longitudinal (REACTION) Study group. Associations of depression with impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in Chinese adults. Diabet Med. 2014 Nov 29. doi: 10.1111/dme.12649. [Epub ahead of print]
- Rodriguez K, Kwan AC, Lai S, Lima JAC, Vigneault D, Sandfort V, Pattanayak P, Ahlman MA, Mallek M, Sibley CT, Bluemke DA. Coronary plaque burden by coronary CT angiography in asymptomatic men and women. Radiology. 2015 Oct;277(1):73-80. doi: 10.1148/radiol.2015142551.
- Bi Y, Jiang Y, He J, Xu Y, Wang L, Xu M, Zhang M, Li Y, Wang T, Dai M, Lu J, Li M, Chen CS, Lai S, Wang W, Wang L, Ning G; 2010 China Noncommunicable Disease Surveillance Group. Status of Cardiovascular Health in Chinese Adults. J Am Coll Cardiol. 2015 Mar 17;65(10):1013-1025. doi: 10.1016/j.jacc.2014.12.044.
- Lai H, Stitzer M, Treisman G, Moore, R, Brinker J, Gerstenblith, Kickler T, Li J, Chen S, Fishman E, Lai S. Cocaine Abstinence and Reduced Use are Associated with Lowered Marker of Endothelial Dysfunction in Africa Americans: A Preliminary Study. J Addict Med 2015 Jul-Aug;9(4):331-9. PMID: 26164164.
- Xu Y, Zhao W, Wang W, Bi Y, Li J, Mi S, Xu M, Lu J, Wang T, Li M, Wang Z, Jiang Y, Wang L, Wang L, Dai M, Zhang D, Lai S, Ning G; 2010 China Noncommunicable Disease Surveillance Group. Plasma Glucose and Hemoglobin A1c for the Detection of Diabetes in Chinese Adults. J Diabetes. J Diabetes. 2016 May;8(3):378-86. doi: 10.1111/1753-0407.12305.
- Sun JC, Xu M, Lu JL, Bi YF, Mu YM, Zhao JJ, Liu C, Chen LL, Shi LX, Li Q, Yang T, Yan L, Wan Q, Wu SL, Liu Y, Wang GX, Luo ZJ, Tang XL, Chen G, Huo YN, Gao ZN, Su Q, Ye Z, Wang YM, Qin GJ, Deng HC, Yu XF, Shen FX, Chen L, Zhao LB, Wang TG, Lai SH, Li DH, Wang WQ, Ning G; Risk Evaluation of Cancers in Chinese Diabetic Individuals: A Longitudinal (REACTION) Study group. Associations of depression with impaired glucose regulation, newly diagnosed diabetes and previously diagnosed diabetes in Chinese adults. Diabet Med. 2015 Jul;32(7):935-43. doi: 10.1111/dme.12649.
- Wang T, Xu Y, Xu M, Wang W, Bi Y, Lu J, Dai M, Zhang D, Ding L, Xu B, Sun J, Zhao W, Jiang Y, Wang L, Li Y, Zhang M, Lai S, Wang L, Ning G. Awareness, treatment and control of cardiometabolic disorders in Chinese adults with diabetes: a national representative population study. Cardiovasc Diabetol. 2015 Feb 26;14:28.
- Xu M, Zhou Y, Xu B, Sun J, Wang T, Lu J, Lai S, Bi Y, Wang W, Ning G. The associations of smoking and alcohol consumption with impaired β cell function in Chinese men. J Diabetes. 2015 May 19. doi: 10.1111/1753-0407.12314. [Epub ahead of print].
- Wang T, Lu J, Wang W, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Xu M, Sun J, Bi Y, Lai S, Bloomgarden ZT, Li D, Ning G; Risk Evaluation of Cancers in Chinese Diabetic Individuals: a Longitudinal (REACTION) Study Group. Sleep duration and snoring associate with hypertension and glycaemic control in patients with diabetes. Diabet Med. 2015 Aug;32(8):1001-7. doi: 10.1111/dme.12809. PMID: 25996982.
- Hammond ER, Wright CM, Lai S, Treisman GJ. Cocaine Use May be Associated with Increased Depression in Persons Infected with HIV. AIDS Behav 2016;20(2):345-52. PMID: 26370100.
- Wang T, Xu M, Xu Y, Lu J, Li M, Chen Y, Wang W, Lai S, Bi Y, Ning G.Association of Bisphenol A Exposure With Hypertension and Early Macrovascular Diseases in Chinese Adults: A Cross-Sectional Study.Medicine (Baltimore). 2015 Oct;94(43):e1814. doi: 10.1097/MD.0000000000001814. PMID: 26512580.
- Baum MK, Campa A, Page JB, Lai S, Tsalaile L, Martinez SS, Burns P, Williams O, Li Y, van Widenfelt E, Bussmann H, Sikhulele M, Makhema J, Essex M, Marlink R. Recruitment, Follow-Up and Characteristics of HIV Infected Adults who Use Illicit Drugs in Southern Africa. J Drug Abuse. 2015;1(1). pii: 7. Epub 2015 Dec 8.
- Bi Y, Wang W, Xu M, Wang T, Lu J, Xu Y, Dai M, Chen Y, Zhang D, Sun W, Ding L, Chen Y, Huang X, Lin L, Qi L, Lai S, Ning G. Diabetes genetic risk score modifies effect of bisphenol A exposure on deterioration in glucose metabolism. J Clin Endocrinol Metab. 2016 Jan;101(1):143-50. PMID:26523527.
- Bi Y, Wang L, Xu Y, Jiang Y, He J, Zhang M, Zhou M, Li Y, Xu M, Lu J, Wang T, Ding L, Dai M, Zhang D, Chen CS, Lai S, Wang W, Wang L, Ning G; 2012 China Noncommunicable Disease and Risk Factor Surveillance in Migrant Workers Study Group. Diabetes-related metabolic risk factors in internal migrant workers in China: a national surveillance study. Lancet Diabetes Endocrinol. 2016 Feb, 4(2):125-135. PMID: 26776861.
- Kiluk BD, Carroll KM, Duhig A, Falk DE, Kampman K, Lai S, Litten RZ, McCann DJ, Montoya ID, Preston KL, Skolnick P, Weisner C, Woody G, Chandler R, Detke MJ, Dunn K, Dworkin RH, Fertig J, Gewandter J, Moeller FG, Ramey T, Ryan M, Silverman K, Strain EC. Measures of outcome for stimulant trials: ACTTION recommendations and research agenda. Drug Alcohol Depend. 2016 Jan 1;158:1-7. doi: 10.1016/j.drugalcdep.2015.11.004. PMID:26652899.
- Sun W, Shi L, Ye Z, Mu Y, Liu C, Zhao J, Chen L, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Sun J, Ding L, Xu Y, Xu M, Dai M, Wang T, Zhang D, Lu J, Bi Y, Lai S, Li D, Wang W, Ning G; REACTION Study Group. Association between the change in body mass index from early adulthood to midlife and subsequent type 2 diabetes mellitus. Obesity (Silver Spring). 2016 Feb 2. doi: 10.1002/oby.21336. PMID: 26833544.
- Lai H, Moore R, Celentano DD, Gerstenblith G, Treisman T, Keruly JC, Kickler T, Li J, Chen S, Lai S, Fishman EK. HIV infection itself may not be associated with subclinical coronary artery disease among African Americans without cardiovascular symptoms. JAHA 2016;5:e002529 doi: 10.1161/JAHA.115.002529. PMID: 27013538.
- Xu M, Zhou Y, Xu B, Sun, J, Wang T, Lu J, Lai S, Bi Y, Wamg W, Ning G. Associations of smoking and alcohol consumption with impaired β-cell function in Chinese men. J Diabetes 2016 May;8(3):434-41. doi: 10.1111/1753-0407.12314. Epub 2015 Jul 14.
- Sandfort V, Lai S, Ahlman M, Mallek M, Liu S, Sibley CT, Turkbey E, Lima JAC, Bluemke DA. Obesity is associated with progression of atherosclerosis during statin treatment. J Am Heart Assoc. 2016 Jul 13;5(7). pii: e003621. doi: 10.1161/JAHA.116.003621.
- Lu J, Mu Y, Su Q, Shi L, Liu C, Zhao J, Chen L, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Sun J, Sun W, Wang T, Du R, Lin L, Dai M, Xu Y, Xu M, Bi Y, Lai S, Li D, Wang W, Ning G; REACTION Study Group. Reduced Kidney Function Is Associated With Cardiometabolic Risk Factors, Prevalent and Predicted Risk of Cardiovascular Disease in Chinese Adults: Results From the REACTION Study. J Am Heart Assoc. 2016 Jul 22;5(7). pii: e003328. doi: 10.1161/JAHA.116.003328.
- Wang T, Xu Y, Xu M, Ning G, Lu J, Dai M, Xu B, Sun J, Sun W, Lai S, Bi Y, Wang W. Circulating Prolactin and Risk of Type 2 Diabetes: A Prospective Study. Am J Epidemiol. 2016 Aug 15;184(4):295-301.
- Sun J, Lu J, Wang W, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Bi Y, Xu M, Xu Y, Dai M, Wang T, Zhang D, Lai S, Ning G; REACTION Study Group. Prevalence of Diabetes and Cardiometabolic Disorders in Spouses of Diabetic Individuals. Am J Epidemiol. 2016 Sep 1;184(5):400-9.
- Li J, Lai H, Chen S, Zhu H, Lai S. Interaction of sex steroid hormones and obesity on insulin resistance and type 2 diabetes in men: the Third National Health and Nutrition Examination Survey. J Diabetes Complications. 2016 Oct 22. pii: S1056-8727(16)30739-5.
- Sandfort V, Bluemke Dam Vargas J, Brinker JA, Gerstenblith G, Kickler T, Zheng G, Li J, Chen S, Lai H, Fishman EK, Lai S. Coronary Plaque Progression and Regression in Asymptomatic African American Chronic Cocaine Users with Obstructive Coronary Stenoses: A Preliminary study. J Addict Med. 2017 Mar/Apr;11(2):126-137. doi: 10.1097/ADM.0000000000000282.
- Sun W, Lu J, Wu S, Bi Y, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Yang T, Yan L, Wan Q, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Wang T, Sun J, Xu M, Xu Y, Chen Y, Dai M, Zhang J, Zhang D, Lai S, Li D, Ning G, Wang W. Association of insulin resistance with breast, ovarian, endometrial and cervical cancers in non-diabetic women.Am J Cancer Res. 2016 Oct 1;6(10):2334-2344.
- Lu J, Wang L, Li M, Xu Y, Jiang Y, Wang W, Li J, Mi S, Zhang M, Li Y, Wang T, Xu M, Zhao Z, Dai M, Lai S, Zhao W, Wang L, Bi Y, Ning G; 2010 China Noncommunicable Disease Surveillance Group. Metabolic Syndrome among Adults in China - The 2010 China Noncommunicable Disease Surveillance. J Clin Endocrinol Metab. 2017 Feb 1; 1;102(2):507-515.
- Liu R, Zou Y, Hong J, Cao M, Cui B, Zhang H, Chen M, Shi J, Ning T, Zhao S, Liu W, Xiong H, Wei C, Qiu Z, Gu W, Zhang Y, Li W, Miao L, Sun Y, Yang M, Wang R, Ma Q, Xu M, Xu Y, Wang T, Chan KK, Zuo X, Chen H, Qi L, Lai S, Duan S, Song B, Bi Y, Liu S, Wang W, Ning G, Wang J. Rare Loss-of-function Variants in NPC1 Predispose to Human Obesity. Diabetes. 2017 Jan 27. pii: db160877. doi: 10.2337/db16-0877. [Epub ahead of print]
- Li J, Lai H, Chen S, Zhu H, Lai S. Gender Differences in the Associations between Urinary Bisphenol A and Body Composition Among US Children: the National Health and Nutrition Examination Survey, 2003-2006. J Epidemiol 2017 Jan 27. pii: S0917-5040(16)30163-0. doi: 10.1016/j.je.2016.12.001.
- Lai S, Gerstenblith G, Moore RD, Celentano DD, Bluemke DA, Treisman G, Liu C-Y, Li J, Chen S, Kickler T, Lai H. Cocaine Use May Modify HIV/ART-Associated Myocardial Steatosis and Hepatic Steatosis. Drug Alcohol Depend. 2017 Aug 1;177:84-92.
- Iantorno M, Schär M, Soleimanifard S, Brown TT, Moore R, Barditch-Crovo P, Stuber M, Lai S, Gerstenblith G, Weiss RG, Hays AG. Coronary artery endothelial dysfunction is present in HIV positive individuals without significant coronary artery disease. AIDS. 2017 Jun 1;31(9):1281-1289.
- Liu C-Y, Lai S, Kawel-Boehm N, Chahal H, Ambale-Venkatesh B, Lima JAC, Bluemke DA. Healthy aging of the left ventricle in relationship to cardiovascular risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA). PLoS One. 2017 Jun 22;12(6):e0179947.
- Liu R, Hong J, Xu, X, Feng Q, Zhang D, Gu Y, Shi S, Liu W, Wang X, Xia H, Liu Z, Cui B, Liang L, Jin J, Ying X, Wang X, Zhao X, Li W, Jia H, Lan Z, Li F, Wang R, Sun Y, Yang Y, Shen Y, Jie Z, Li J, Chen X, Zhong H, Xie H, Zhang Y, Gu W, Deng X, Shen B, Xu X, Yang H, Xu G, Bi Y, Lai S, Wang J, Qi L, Madsen L, Wang J, Ning G, Kristiansen K, Wang W. Alterations of gut microbiome and blood metabolites in young obese individuals and their normalization after weight loss intervention. Nat Med. 2017 Jul;23(7):859-868. doi: 10.1038/nm.4358.
- Li J, Lai H, Yang L, Zhu H, Chen S, Lai S. Age and gender differences in the association between serum 25-hydroxyvitamin D and stroke in the general U.S. population: the National Health and Nutrition Examination Survey, 2001-2006. J Stroke Cerebrovasc Dis 2017 Nov;26(11):2510-2518.
- Lin L, Lu J, Chen L, Mu Y, Ye Z, Liu C, Chen G, Shi L, Zhao J, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Huo Y, Gao Z, Su Q, Wang Y, Qin G, Deng H, Yu X, Feixia S, Chen L, Zhao L, Xu Y, Xu M, Peng K, Du R, Dai M, Li M, Wang T, Zhao Z, Lai S, Li D, Bi Y, Wang W, Ning G; REACTION Study Group. Glycemic status and chronic kidney disease in Chinese adults: Findings from the REACTION Study. J Diabetes. 2017 Sep;9(9):837-845. doi: 10.1111/1753-0407.12490.
- Liu CY, Heckbert SR, Lai S, Ambale-Venkatesh B, Ostovaneh MR, McClelland RL, Lima JAC, Bluemke DA. Association of Elevated NT-proBNP With Myocardial Fibrosis in the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol. 2017 Dec 26;70(25):3102-3109. doi: 10.1016/j.jacc.2017.10.044.
- Li, J, Lai H, Chen S, Lai S. Impact of cocaine use on protease inhibitor-associated dyslipidemia in HIV-infected adults. Int J STD AIDS. 2018 Jul;29(8):781-789.
- Lai S, Heaphy CM, Rizzo AJ, Celentano DD, Gerstenblith G, Li J, Moore, RD, Treisman G, Chen S, Foster P, Kickler T, Lai H. Cocaine Use May Induce/Accelerate Telomere Shortening in Individuals with HIV Infection. Prog Neuropsychopharmacol Biol Psychiatry 2018 June 8;84(Pt A):11-17.
- Hays AG, Iantorno M, Schär M, Lai S, Czarny M, Breton E, Palmer RN, Whelton A, Weiss RG, Gerstenblith G. The influence of febuxostat on coronary artery endothelial dysfunction in patients with coronary artery disease: A phase 4 randomized, placebo-controlled, double-blind, crossover trial. Am Heart J. 2018 Mar;197:85-93.
- Foster P, Sokoll L, Gerstenblith G, Fishman EK, Li J, Kickler T, Chen S, Tai H, Lai H, Lai S. Circulating levels of cardiac troponin T are associated with coronary noncalcified plaque burden in HIV–infected adults: a pilot study. Int J STD AIDS. 2019 Mar;30(3):223-230.
- Iantorno M, Soleimanifard S, Schär M, Brown TT, Bonanno G, Barditch-Crovo P, Mathews L, Lai S, Gerstenblith G, Weiss RG, Hays AG. Regional coronary endothelial dysfunction is related to the degree of local epicardial fat in people with HIV. Atherosclerosis. 2018 Aug 17;278:7-14. doi: 10.1016/j.atherosclerosis.2018.08.002. [Epub ahead of print]
- Liu CY, Lai S, Lima JAC. MRI gadolinium dosing on basis of blood volume. Magn Reson Med. 2019; 81(2): 1157-1164.
- Li J, Lai H, Chen S, Kickler T, Lai S. Cocaine use modifies the association between antiretroviral therapy and endothelial dysfunction among adults with HIV infection. J Med Virol 2019 Sep;91(9):1660-1667.
- Li J, Lai H, Chen D, Chen S, Lai S. Impact of Cardiovascular Disease on Health Insurance Coverage and Healthcare Use under Economic Stress: The National Health and Nutrition Examination Survey, 2003-2012. Osong Public Health Res Perspect. 2019 Jun;10(3):123-136.
- Lu J, He J, Li M, Tang X, Hu R, Shi L, Su Q, Peng K, Xu M, Xu Y, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Qin G, Wan Q, Chen G, Dai M, Zhang D, Gao Z, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Du R, Cheng D, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Bloomgarden ZT, Chen L, Zhao J, Mu Y, Ning G, Wang W, Bi Y; 4C Study Group.Predictive Values of Fasting Glucose, Postload Glucose, and Hemoglobin A1c on Risk of Diabetes and Complications in Chinese Adults. Diabetes Care. 2019 Aug;42(8):1539-1548. doi: 10.2337/dc18-1390.
- Zhao Z, Li M, Li C, Wang T, Xu Y, Zhan Z, Dong W, Shen Z, Xu M, Lu J, Chen Y, Lai S, Fan W, Bi Y, Wang W, Ning G.Dietary preferences and diabetic risk in China: A large-scale nationwide internet data based study. J Diabetes. 2019 Jul 9. doi: 10.1111/1753-0407.12967. [Epub ahead of print]
- Wang T, Lu J, Su Q, Chen Y, Bi Y, Mu Y, Chen L, Hu R, Tang X, Yu X, Li M, Xu M, Xu Y, Zhao Z, Yan L, Qin G, Wan Q, Chen G, Dai M, Zhang D, Gao Z, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Bloomgarden ZT, Shi L, Ning G, Zhao J, Wang W; 4C Study Group. Ideal Cardiovascular Health Metrics and Major Cardiovascular Events in Patients With Prediabetes and Diabetes. JAMA Cardiol. 2019 Jul 31. doi: 10.1001/jamacardio.2019.2499. [Epub ahead of print]
- Li J, Lai H, Chen S, Lai S. Cocaine use modifies the association of antiretroviral therapy regimens with obesity in HIV-infected adults. Obesity Medicine 2019, accepted.
- Fu H, Deng W, Yao L, Gong M, Lai S, Liu J, Li M, Xu H, Wang J. Urinary NOx, a novel potential biomarker for autism spectrum disorder. Free Radic Biol Med. 2019 Nov 7. pii: S0891-5849(19)30932-3. doi: 10.1016/j.freeradbiomed.2019.11.001. [Epub ahead of print]
- Wang T, Lu J, Shi L, Chen G, Xu M, Xu Y, Su Q, Mu Y, Chen L, Hu R, Tang X, Yu X, Li M, Zhao Z, Chen Y, Yan L, Qin G, Wan Q, Dai M, Zhang D, Gao Z, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Lai S, Bi Y, DeFronzo RA, Wang W, Ning G; China Cardiometabolic Disease and Cancer Cohort Study Group. Association of insulin resistance and β-cell dysfunction with incident diabetes among adults in China: a nationwide, population-based, prospective cohort study. Lancet Diabetes Endocrinol. 2020 Feb;8(2):115-124.
- Fu H, Deng W, Yao L, Gong M, Lai S, Liu J, Li M, Xu H, Wang J. Urinary NOx, a novel potential biomarker for autism spectrum disorder. Free Radic Biol Med. 2020 Jan;146:350-356.
- Zhang Y, Gu Y, Ren H, Wang S, Zhong H, Zhao X, Ma J, Gu X, Xue Y, Huang X, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Kong P, Hou G, Gao M, Shi Z, Li X, Qiu Y, Zou Y, Yang H, Wang J, Xu G, Lai S, Li J, Ning G, Wang W. Gut microbiome related effect of Berberine and probiotics in type 2 diabetes (the PREMOTE Study). Nat Commun. 2020 Oct 6;11(1):5015.
- Lu J, Li M, Xu Y, Qin Y, Li Q, Wang T, Hu R, Shi L, Su Q, Xu M, Zhao Z, Chen Y, Yu X, Yan L, Du R, Hu C, Qin G, Wng Q, Chen G, Dai M, Zhng D, Gao Z, Wang G, Shen F, Luo Z, Chen L, Huo Y, Ye Z, Tang X, Zhng Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Bloomgarden ZT, Chen L, Zhao J, Mu Y, Ning G, Wang W. Early Life Famine Exposure, Ideal Cardiovascular Health Metrics, and Risk of Incident Diabetes: Findings From the 4C Study. Diabetes Care. 2020 Aug;43(8):1902-1909. doi:10.2337/dc19-2325.
- Chen DH, Kolossvary M, Chen S, Lai H, Yeh H-C, Lai S. Long-term cocaine use is associated with increased coronary plaque burden – a pilot study. Am J Drug Alcohol Abuse. 2020 Nov 1;46(6):805-811.
- Lu J, Wang S, Li M, Gao Z, Xu Y, Zhao X, Hu C, Zhang Y, Liu R, Hu R, Shi L, Zheng R, Du R, Su Q, Wang J, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Wang X, Li Q, Qin G, Wan Q, Chen G, Xu M, Dai M, Zhang D, Tang X, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Mu Y, Chen L, Zhao J, Xu G, Ning G, Bi Y, Wang W; 4C Study Group. Association of Serum Bile Acids Profile and Pathway Dysregulation With the Risk of Developing Diabetes among Normoglycemic Chinese Adults: Findings From the 4C Study. Diabetes Care. 2020 Dec 18:dc200884. doi: 10.2337/dc20-0884. Epub ahead of print. PMID: 33355246.
- Fang W, Jiang J, Su L, Shu T, Liu H, Lai S, Ghiladi RA, Wang J. The role of NO in COVID-19 and potential therapeutic strategies. Free Radic Biol Med. 2020 Dec 22;163:153-162. doi: 10.1016/j.freeradbiomed.2020.12.008. Epub ahead of print. PMID: 33347987; PMCID: PMC7754882.
- Lu J, Wang S, Li M, Gao Z, Xu Y, Zhao X, Hu C, Zhang Y, Liu R, Hu R, Shi L, Zheng R, Du R, Su Q, Wang J, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Wang X, Li Q, Qin G, Wan Q, Chen G, Xu M, Dai M, Zhang D, Tang X, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Mu Y, Chen L, Zhao J, Xu G, Ning G, Bi Y, Wang W; 4C Study Group. Association of Serum Bile Acids Profile and Pathway Dysregulation With the Risk of Developing Diabetes Among Normoglycemic Chinese Adults: Findings From the 4C Study. Diabetes Care. 2021 Feb;44(2):499-510.
- Kolossváry M, Gerstenblith G, Bluemke DA, Fishman EK, Gerstenblith G, Bluemke DA, Mandler R, Kickler T, Chen S, Bhatia S, Lai S, Lai H. Contribution of risk factors to the development of coronary atherosclerosis as confirmed via coronary CT angiography – a longitudinal radiomics-based study. Radiology 2021 Apr;299(1):97-106. doi: 10.1148/radiol.2021203179.
- Kolossváry M, Fishman EK, Gerstenblith G, Bluemke DA, Mandler RN, Celentano D, Kickler TS, Bazr S, Chen S, Lai S, Lai H. Cardiovascular risk factors and illicit drug use may have a more profound effect on coronary atherosclerosis progression in people living with HIV. Eur Radiol. 2021 May;31(5):2756-2767. doi: 10.1007/s00330-021-07755-7. PMID: 33660033.
- Hays AG, Schär M, Barditch-Crovo P, Bagchi S, Bonanno G, Meyer J, Afework Y, Streeb V, Stradley S, Kelly S, Anders NM, Margolick JB, Lai S, Gerstenblith G, Weiss RG. A randomized, placebo-controlled, double-blinded clinical trial of colchicine to improve vascular health in people living with HIV. AIDS. 2021 Jun 1;35(7):1041-1050. doi: 10.1097/QAD.0000000000002845. PMID: 33587443.
- Yao L, Cai K, Mei F, Wang X, Fan C, Jiang H, Xie F, Li Y, Bai L, Peng K, Deng W, Lai S, Wang J. Urine Nitric Oxide Is Lower in Parents of Autistic Children. Front Psychiatry. 2021 May 21;12:607191. doi: 10.3389/fpsyt.2021.607191. PMID: 34093255; PMCID: PMC8175662.
- Yao L, Fu H, Bai L, Deng W, Xie F, Li Y, Zhang R, Xu X, Wang T, Lai S, Wang J. Saliva nitrite is higher in male children with autism spectrum disorder and positively correlated with serum nitrate. Redox Rep. 2021 Dec;26(1):124-133. doi: 10.1080/13510002.2021.1959133. PMID: 34323675; PMCID: PMC8330712.
- Hays AG, Schär M, Bonanno G, Lai S, Meyer J, Afework Y, Steinberg A, Stradley S, Gerstenblith G, Weiss RG. Randomized Trial of Anti-inflammatory Medications and Coronary Endothelial Dysfunction in Patients With Stable Coronary Disease. Front Cardiovasc Med. 2021 Oct 15;8:728654. doi: 10.3389/fcvm.2021.728654.
- Kolossváry M, Celentano D, Gerstenblith G, Bluemke DA, Mandler RN, Fishman EK, Bhatia S, Chen S, Lai S, Lai H. HIV indirectly accelerates coronary artery disease by promoting the effects of risk factors - longitudinal observational study. Sci Rep 2021, 11:23110.
- Wang S, Ren H, Zhong H, Zhao X, Li C, Ma J, Gu X, Xue Y, Huang S, Yang J, Chen L, Chen G, Qu S, Liang J, Qin L, Huang Q, Peng Y, Li Q, Wang X, Zou Y, Shi Z, Li X, Li T, Yang H, Lai S, Xu G, Li J, Zhang Y, Gu Y, Wang W. Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study. Gut Microbes. 2022 Jan-Dec;14(1):2003176. doi: 10.1080/19490976.2021.2003176. PMID: 34923903; PMCID: PMC8726654.
- Keceli G, Gupta A, Sourdon J, Gabr R, Schär M, Dey S, Tocchetti CG, Stuber A, Agrimi J, Zhang Y, Leppo M, Steenbergen C, Lai S, Yanek LR, O'Rourke B, Gerstenblith G, Bottomley PA, Wang Y, Paolocci N, Weiss RG. Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure. Circ Res. 2022 Feb 3:CIRCRESAHA121319648. doi: 10.1161/CIRCRESAHA.121.319648.
- Tamargo JA, Sherman KE, Sékaly RP, Bordi R, Schlatzer D, Lai S, Khalsa JH, Mandler RN, Ehman RL, Baum MK. Cocaethylene, simultaneous alcohol and cocaine use, and liver fibrosis in people living with and without HIV. Drug Alcohol Depend. 2022 Mar 1;232:109273. doi: 10.1016/j.drugalcdep.2022.109273. Epub 2022 Jan 12. PMID: 35033954; PMCID: PMC8885871.
- Vavuranakis MA, Jones SR, Ziogos E, Blaha MJ, Williams MS, Foran P, Schindler TH, Lai S, Schulman SP, Gerstenblith G, Leucker TM. The Trajectory of Lipoprotein(a) During the Peri- and Early Postinfarction Period and the Impact of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition. Am J Cardiol. 2022 May 15;171:1-6.
- Jávorszky N, Homonnay B, Gerstenblith G, Bluemke D, Kiss P, Török M, Celentano D, Lai H, Lai S, Kolossváry M. Deep learning-based atherosclerotic coronary plaque segmentation on coronary CT angiography. Eur Radiol. 2022 May 7. doi: 10.1007/s00330-022-08801-8. Epub ahead of print. PMID: 35524783.
- Kolossváry M, Bluemke DA, Fishman EK, Gerstenblith G, Celentano D, Mandler RN, Khalsa J, Bhatia S, Chen S, Lai S, Lai H. Temporal assessment of lesion morphology on radiological images beyond lesion volumes-a proof-of-principle study. Eur Radiol. 2022 Dec;32(12):8748-8760. doi: 10.1007/s00330-022-08894-1. PMID: 35648210; PMCID: PMC9712148.
- Samuel TJ, Lai S, Schär M, Wu KC, Steinberg AM, Wei AC, Anderson M, Tomaselli GF, Gerstenblith G, Bottomley PA, Weiss RG. Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in heart failure patients. JCI Insight. 2022 May 17:e157557. doi: 10.1172/jci.insight.157557. Epub ahead of print. PMID: 35579938.
- Lai H, Bluemke DA, Fishman EK, Gerstenblith G, Celentano DD, Treisman G, Foster P, Mandler R, Khalsa J, Chen S, Bhatia S, Kolossváry M, Lai S. High-risk Coronary Plaque Regression in Cash-based Contingency Management Intervention Among Cocaine Users With HIV-associated Subclinical Coronary Atherosclerosis. J Addict Med. 2023 March/April; 17(2); 147-154. doi: 10.1097/ADM.0000000000001057. PMID: 36001073.
- Wang S, Li M, Lin H, Wang G, Xu Y, Zhao X, Hu C, Zhang Y, Zheng R, Hu R, Shi L, Du R, Su Q, Wang J, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Liu R, Wang X, Li Q, Qin G, Wan Q, Chen G, Xu M, Dai M, Zhang D, Tang X, Gao Z, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Lai S, Mu Y, Chen L, Li D, Xu G, Ning G, Wang W, Bi Y, Lu J; 4C Study Group. Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study. Cell Rep Med. 2022 Sep 20;3(9):100727. doi: 10.1016/j.xcrm.2022.100727. Epub 2022 Aug 22. PMID: 35998626; PMCID: PMC9512668.
- Gorbach PM, Rosen AD, Moore R, Shoptaw S, Mustanski B, Mehta SH, Kirk GD, Baum MK, Milloy MJ, Hayashi K, DeBeck K, Kipke M, Lai S, Siminski S, Javanbakht M. Use of COVID-19 testing in the first year of the COVID-19 pandemic among cohorts of people at the intersection of drug use and HIV. Drug Alcohol Depend. 2022 Dec 1;241:109622. doi: 10.1016/j.drugalcdep.2022.109622.
- Adebajo SB, Adebiyi R, Chama J, Bello S, Ononaku U, Aka A, Lai S, Baral SD, Dyer TV, Crowell TA, Nowak RG, Charurat M; TRUST/RV368 Study Group. Depression and Sexual Stigma Are Associated With Cardiometabolic Risk Among Sexual and Gender Minorities Living With HIV in Nigeria. J Acquir Immune Defic Syndr. 2023 Jan 1;92(1):50-58. doi: 10.1097/QAI.0000000000003096. PMID: 36150037; PMCID: PMC9742173.
- Niu J, Zhang X, Li M, Wu S, Zheng R, Chen L, Huo Y, Xu M, Wang T, Zhao Z, Wang S, Lin H, Qin G, Yan L, Wan Q, Chen L, Shi L, Hu R, Tang X, Su Q, Yu X, Qin Y, Chen G, Gao Z, Wang G, Shen F, Luo Z, Chen Y, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Li Q, Mu Y, Zhao J, Bi Y, Ning G, Wang W, Lu J, Xu Y; for theChina Cardiometabolic Disease and Cancer Cohort (4C) Study Group; Steering Committee; Ning G, Mu Y, Wang W, Liu C, Bi Y, Li D, Lai S, Bloomgarden ZT; Working Group; Wang W, Bi Y, Lu J, Li M, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Yang T, Yan L, Wan Q, Wu S, Wang G, Luo Z, Qin Y, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Hu R, Wang Y, Qin G, Yu X, Shen F, Chen L, Zhao J, Deng H. Risk of cardiovascular disease, death, and renal progression in diabetes according to albuminuria and estimated glomerular filtration rate. Diabetes M 2023 Jan 11:101420. doi: 10.1016/j.diabet.2023.101420.
- Bagchi S, Kwapong YA, Schär M, Bonanno G, Streeb V, Lai S, Gerstenblith G, Weiss RG, Hays AG. The Relationship between Impaired Coronary Endothelial Function and Systemic Markers of Inflammation in People Living with HIV. J Acquir Immune Defic Syndr. 2023 Jan 11. doi: 10.1097/QAI.0000000000003162. Epub ahead of print. PMID: 36634369.
- Lai H, Celentano DD, Treisman G, Khalsa J, Gerstenblith G, Page B, Mandler RN, Yang Y, Salmeron B, Bhatia S, Chen S, Lai S, Goodkin K, Charurat M. Cocaine use may moderate the associations of HIV and female sex with neurocognitive impairment in a predominantly African American population disproportionately impacted by HIV and substance use. AIDS Patient Care STDS. 2023 Apr 20. doi: 10.1089/apc.2023.0006.
- Ziogos E, Vavuranakis MA, Harb T, Foran PL, Blaha MJ, Jones SR, Lai S, Gerstenblith G, Leucker TM. Lipoprotein(a) concentrations in acute myocardial infarction patients are not indicative of levels at six month follow-up. Eur Heart J Open. 2023 Apr 5;3(2):oead035. doi: 10.1093/ehjopen/oead035. PMID: 37095769; PMCID: PMC10122422.
- Ziogos E, Chelko SP, Harb T, Engel M, Vavuranakis MA, Landim-Vieira M, Walsh EM, Lai S, Halushka MK, Gerstenblith G, Leucker TM. Platelet activation and endothelial dysfunction biomarkers in acute coronary syndrome: the impact of PCSK9 inhibition. Eur Heart J Cardiovasc Pharmacother. 2023 Jul 19:pvad051. doi: 10.1093/ehjcvp/pvad051. Epub ahead of print. PMID: 37468450.
- Harb T, Ziogos E, Schär M, Brown TT, Lai S, Gerstenblith G, Hays AG, Leucker TM. Rapid Improvement of Coronary Endothelial Function With PCSK9 Inhibition in People With HIV Is Associated With Reduced Lipoprotein (a) and Not LDL-cholesterol. Circ Cardiovasc Imaging. 2023 Oct;16(10):e015693. doi: 10.1161/CIRCIMAGING.123.015693. Epub 2023 Sep 29. PMID: 37772401; PMCID: PMC10591943.
- Lai H, Treisman G, Celentano DD, Gerstenblith G, Mandler RN, Khalsa J, Charurat M, Lai S, Pearson G. Elevated homocysteine levels may moderate and mediate the association between HIV and cognitive impairment among middle-aged and older adults in an underserved population in Baltimore, Maryland. Int J STD AIDS. 2024 Mar;35(4):296-307. doi: 10.1177/09564624231218762. Epub 2023 Dec 8. PMID: 38065684.
- Leucker TM, Harb T, Gerstenblith G, Celentano DD, Ziogos E, Treisman G, Mandler RN, Khalsa J, Charurat M, Lai S, Lai H. Homocysteine modifies the association of coronary stenosis and HIV infection in an inner city African American population. Int J STD AIDS. 2024 Mar 26:9564624241242171. doi: 10.1177/09564624241242171. Epub ahead of print. PMID: 38531830.
- Hu C, Wang S, Lin H, Wan Q, Zheng R, Zhu Y, Li M, Xu Y, Xu M, Zheng J, Chen L, Zeng T, Hu R, Ye Z, Shi L, Su Q, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Qin G, Chen G, Dai M, Zhang D, Tang X, Gao Z, Shen F, Gu X, Luo Z, Qin Y, Chen L, Hou X, Huo Y, Li Q, Wang G, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Mu Y, Lai S, Li D, Ning G, Wang W, Hu W, Bi Y, Lu J; 4C Study Group. Body size, insulin sensitivity, metabolic health and risk of cardiovascular disease in Chinese adults: Insights from the China Cardiometabolic Disease and Cancer Cohort (4C) study. Diabetes Obes Metab. 2024 Feb 28. doi: 10.1111/dom.15525. Epub ahead of print. PMID: 38419419.
- Bradley H, Luisi N, Carter A, Pigott TD, Abramovitz D, Allen ST, Asher A, Austin C, Bartholomew TS, Baum M, Board A, Boodram B, Borquez A, Brookmeyer KA, Buchacz K, Burnett J, Cooper HLF, Crepaz N, Debeck K, Feinberg J, Fong C, Freeman E, Furukawa NW, Genberg B, Gorbach P, Hagan H, Hayashi K, Huriaux E, Hurley H, Keruly J, Kristensen K, Lai S, Martin NK, Mateu-Gelabert P, Mcclain GM Jr, Mehta S, Mok WY, Reynoso M, Strathdee S, Torigian N, Weng CA, Westergaard R, Young A, Jarlais DCD. Assessing COVID-19 pandemic impacts on the health of PWID using a novel data sharing model. AIDS. 2024 Nov 28. doi: 10.1097/QAD.0000000000004076. Epub ahead of print. PMID: 39612241.
- Harb T, Ziogos E, Amat-Alarcon N, Lai S, Gerstenblith G, Arvanitis M, Leucker TM. Peroxisome Proliferator-Activated Receptor Gamma Regulates Interleukin-6-Induced Lipoprotein (a) Gene Expression in Human HepG2 Cells. J Cardiovasc Pharmacol. 2024 Dec 1;84(6):562-564. doi: 10.1097/FJC.0000000000001634. PMID: 39270008; PMCID: PMC11627301.
- Li M, Li J, Xu Y, Gao J, Cao Q, Ding Y, Xin Z, Lu M, Li X, Song H, Shen J, Hou T, He R, Li L, Zhao Z, Xu M, Lu J, Wang T, Wang S, Lin H, Zheng R, Zheng J, Baker CJ, Lai S, Johnson NA, Ning G, Twigg SM, Wang W, Liu Y, Bi Y. Effect of 5:2 Regimens: Energy-Restricted Diet or Low-Volume High-Intensity Interval Training Combined With Resistance Exercise on Glycemic Control and Cardiometabolic Health in Adults With Overweight/Obesity and Type 2 Diabetes: A Three-Arm Randomized Controlled Trial. Diabetes Care. 2024 Jun 1;47(6):1074-1083. doi: 10.2337/dc24-0241. PMID: 38638032; PMCID: PMC11116924.
- Lu J, Li M, He J, Xu Y, Zheng R, Zheng J, Qin G, Qin Y, Chen Y, Tang X, Ye Z, Xu M, Wang T, Shi L, Su Q, Yu X, Yan L, Zhao Z, Wan Q, Chen G, Gao Z, Wang G, Shen F, Gu X, Luo Z, Chen L, Hou X, Huo Y, Li Q, Qiao H, Zhang Y, Zeng T, Hu C, Cao Q, Jia X, Liu C, Wang Y, Wu S, Yang T, Deng H, Qi H, Wu X, Zhang D, Dai M, Li D, Lai S, Chen L, Zhao J, Mu Y, Hu W, Ning G, Hu R, Bi Y, Wang W; 4C Study Group. Association of social determinants, lifestyle, and metabolic factors with mortality in Chinese adults: A nationwide 10-year prospective cohort study. Cell Rep Med. 2024 Aug 20;5(8):101656. doi: 10.1016/j.xcrm.2024.101656. Epub 2024 Jul 26. PMID: 39067445; PMCID: PMC11384959.
- Wang S, Hu C, Lin H, Jia X, Hu R, Zheng R, Li M, Xu Y, Xu M, Zheng J, Zhao X, Li Y, Chen L, Zeng T, Ye Z, Shi L, Su Q, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Qin G, Wan Q, Chen G, Dai M, Zhang D, Qiu B, Zhu X, Liu R, Wang X, Tang X, Gao Z, Shen F, Gu X, Luo Z, Qin Y, Chen L, Hou X, Huo Y, Li Q, Wang G, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Mu Y, Xu G, Lai S, Li D, Ning G, Wang W, Bi Y, Lu J; 4C Study Group. Association of circulating long-chain free fatty acids and incident diabetes risk among normoglycemic Chinese adults: a prospective nested case-control study. Am J Clin Nutr. 2024 Aug;120(2):336-346. doi: 10.1016/j.ajcnut.2024.05.003. Epub 2024 May 8. PMID: 38729573.
- Jia X, Lin H, Zheng R, Wang S, Ding Y, Hu C, Li M, Xu Y, Xu M, Wang G, Chen L, Zeng T, Hu R, Ye Z, Shi L, Su Q, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Qin G, Wan Q, Chen G, Dai M, Zhang D, Qiu B, Zhu X, Zheng J, Tang X, Gao Z, Shen F, Gu X, Luo Z, Qin Y, Chen L, Hou X, Huo Y, Li Q, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Mu Y, Lai S, Li D, Hu W, Ning G, Wang W, Bi Y, Lu J; 4C Study Group. Exploring age and gender disparities in cardiometabolic phenotypes and lipidomic signatures among Chinese adults: a nationwide cohort study. Life Metab. 2024 Aug 2;3(5):loae032. doi: 10.1093/lifemeta/loae032. PMID: 39872143; PMCID: PMC11749084.
- Wang S, Lin H, Jia X, Lin Y, Hu C, Li M, Xu Y, Xu M, Zheng J, Zhao X, Li Y, Chen L, Zeng T, Hu R, Ye Z, Shi L, Su Q, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Qin G, Wan Q, Chen G, Dai M, Zhang D, Qiu B, Zhu X, Liu R, Wang X, Tang X, Gao Z, Shen F, Gu X, Luo Z, Qin Y, Chen L, Hou X, Huo Y, Li Q, Wang G, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Zhao J, Mu Y, Xu G, Lai S, Li D, Ning G, Wang W, Bi Y, Lu J. Circulating short-chain and branched short-chain fatty acids and the risk of incident type 2 diabetes: findings from the 4C study. Life Metab. 2025 Jan 22;4(2):loaf001. doi: 10.1093/lifemeta/loaf001. PMID: 40078932; PMCID: PMC11897982.
- Bradley H, Luisi N, Carter A, Pigott TD, Abramovitz D, Allen ST, Asher A, Austin C, Bartholomew TS, Baum M, Board A, Boodram B, Borquez A, Brookmeyer KA, Buchacz K, Burnett J, Cooper HLF, Crepaz N, Debeck K, Feinberg J, Fong C, Freeman E, Furukawa NW, Genberg B, Gorbach P, Hagan H, Hayashi K, Huriaux E, Hurley H, Keruly J, Kristensen K, Lai S, Martin NK, Mateu-Gelabert P, Mcclain GM Jr, Mehta S, Mok WY, Reynoso M, Strathdee S, Torigian N, Weng CA, Westergaard R, Young A, Des Jarlais DC. Assessing coronavirus disease 2019 pandemic impacts on the health of people who inject drugs using a novel data sharing model. AIDS. 2025 Mar 15;39(4):434-447. doi: 10.1097/QAD.0000000000004076. Epub 2024 Dec 23. PMID: 39612241; PMCID: PMC11872276.
- Lai H, Zhuo J, Treisman G, Gerstenblith G, Celentano DD, Yang Y, Salmeron BJ, Gu H, Leucker TM, Liang X, Mandler RN, Khalsa J, Peña-Nogales Ó , Chen S, Lai S, Rosenthal E, Goodkin K, Magnotta VA. HIV and Low Omega-3 Levels May Heighten Hippocampal Volume Differences Between Men and Women With Substance Use. Brain Behav Immun Health. 2025 Apr 5;45:100988. doi: 10.1016/j.bbih.2025.100988. PMID: 40248088; PMCID: PMC12005316.
- Lewsey SC, Samuel TJ, Schar M, Sourdon J, Goldenberg JR, Yanek LR, Lai S, Steinberg AM,, Bottomley PA, Gerstenblith G, Weiss RG. Skeletal Muscle Quantity versus Quality in Heart Failure: Exercise intolerance and outcomes in older HFpEF patients are related to abnormal skeletal muscle metabolism rather than age-related skeletal muscle loss. Circ Heart Failure, 2025 Jun 19:e012512. doi: 10.1161/CIRCHEARTFAILURE.124.012512. Epub ahead of print. PMID: 40534551.
Research Interests
Dr. Shenghan Lai has been heavily involved in epidemiology and prevention of HIV infection in countries with greater HIV prevalence for more than 10 years. He has focused on high-risk groups such as intravenous drug users, sex workers, and men who engage in sex with other men. Dr. Lai is recognized as a leading epidemiology researcher in the infectious disease epidemiology, and world renowned for his research on the effects of HIV infection and cocaine use on sub-clinical cardiovascular disease. He is the principal investigator of several NIH-supported studies, focusing on HIV natural history and cardiovascular complications of HIV and drug abuse. Dr. Lai received his degrees from Peking Union Medical College in Beijing, China, and the Uniformed Services University of the Health Sciences in Bethesda, Maryland. He has more than 250 peer-reviewed publications and numerous book chapters.