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Michelle A. Ghert, MD

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For an appointment call 410-448-6400

Education and Training

  • Stanford University, B.A.S., 1992
  • Vanderbilt University, MD, 1996
  • Duke University, Residency in Orthopaedic Surgery, 2002
  • University of Toronto, Fellowship in Orthopaedic Oncology, 2004


Michelle Ghert, MD, FRCSC, is an orthopaedic surgeon specializing in musculoskeletal oncology. She has extensive experience in the diagnosis and surgical management of benign and malignant tumors of the musculoskeletal system and in complex limb reconstruction. Dr. Ghert is also a national and international leader in sarcoma care and multidisciplinary management. Dr. Ghert leads international randomized controlled trials in orthopaedic oncology, including the Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) trial (NCT01479283) and the Surveillance after Extremity Tumor Surgery (SAFETY) randomized controlled trial (, NCT03944798).

Dr. Ghert completed her pre-medical studies at Stanford University in California and received her medical degree from Vanderbilt University in Tennessee. She completed her residency in orthopaedic surgery at Duke University in North Carolina, and her musculoskeletal oncology fellowship at the University of Toronto in Ontario, Canada. She began her independent clinical and academic career as Assistant Professor at McMaster University in Hamilton, Ontario, Canada in 2005, and was promoted to Professor in 2017. Dr. Ghert was recruited to the University of Maryland where she opened her clinical practice in 2024.   

Research/Clinical Keywords

randomized controlled trials,orthopaedic oncology, musculoskeletal tumors, surgery, sarcoma, skeletal metastases

Highlighted Publications

Most Highly Cited Publications

Ghert, Michelle, et al. "Comparison of prophylactic intravenous antibiotic regimens after endoprosthetic reconstruction for lower extremity bone tumors: a randomized clinical trial." JAMA oncology 8.3 (2022): 345-353.

Mak, Isabella WY, Nathan Evaniew, and Michelle Ghert. "Lost in translation: animal models and clinical trials in cancer treatment." American journal of translational research   6.2 (2014): 114.

Pervaiz, N., Colterjohn, N., Farrokhyar, F., Tozer, R., Figueredo, A., & Ghert, M. (2008). A systematic meta‐analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft‐tissue sarcoma. Cancer: Interdisciplinary International Journal of the American Cancer Society,   113(3), 573-581.

Additional Publication Citations

Awards and Affiliations

2023 Ann Doner Vaughan Kappa Delta Award

2023 Kappa Delta Ann Doner Vaughn Award Presented to Michelle Ghert, MD, FRCSC, and the PARITY Investigators for First-Ever International Multi-Center Randomized Controlled Trial in Orthopaedic Oncology (

Ghert receives Kappa Delta Ann Doner Vaughn Award at AAOS Annual Meeting (

Michelle Ghert, M.D., Team Win Kappa Delta Ann Doner Vaughn Award | Orthopedics This Week (

2019 J. Édouard Samson Award:

Dr. Michelle Ghert  for her research proposal entitled: The Prophylactic Antibiotic Regimens in Tumour Surgery (PARITY) Trial: Unprecedented international collaboration in orthopaedic oncology” Journal of the American Medical Association Oncology: Comparison of Prophylactic Intravenous Antibiotic Regimens After Endoprosthetic Reconstruction for Lower Extremity Bone Tumors A Randomized Clinical Trial

Other Affiliations

Professor, Part-Time, McMaster University

Grants and Contracts

Active Grants

NIH/NIAMS R34AR084146-01:
A Planning Grant for a Multi-Center Randomized Controlled Trial Comparing Resection and Endoprosthetic Reconstruction vs. Internal Fixation for Metastatic Bone Disease of the Proximal Femur

DOD CA230126:
Deficits in Cellular Redox Balance in Survivors of Lower-Extremity Sarcoma: A Potential Target for Improving Recovery Time, Function, and Quality of Life

Canadian Cancer Society Grant 70812:
The Proximal Femur Resection or Internal Fixation for Metastases (PERFORM) Pilot Randomized Controlled Trial