Skip to main content

Dominique R. Bollino, PhD

Academic Title:

Research Associate

Primary Appointment:


Phone (Primary):


Education and Training

Frostburg State University, B.S. Biology 2008

University of Maryland, Baltimore, Ph.D. 2015

     Thesis Advisor- Dr. Laure Aurelian

Univerisity of Maryland, Baltimore, Postdoctoral fellowship 2015-2019

     Department of Microbiology and Immunology, Laboratory of Dr. Tonya Webb

University of Maryland Greenebaum Cancer Center, Postdoctoral fellowship, 2019

     Program in Oncology, Laboratory of Dr. Ashkan Emadi


Research/Clinical Keywords

Acute myeloid leukemia, FLT3 inhibition, pancreatic cancer, glutamine metabolism

Highlighted Publications

1. Colunga, A., Bollino, D., Schech, A. and Aurelian, L. “Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to DPK oncolytic activity in melanoma.” Gene Therap. 2014; 21: 371-378.

2. Bollino D, Balan I, Aurelian LA. “Valproic acid induces neuronal cell death through a novel calpain-dependent necroptosis pathway.” J Neurochem. 2015; 133 (2):174-86.

3. June HL, Liu J, Warnock KT, Bell KA, Balan I, Bollino D, Puche A, Aurelian L. “CRF-Amplified Neuronal TLR4/MCP-1 Signaling Regulates Alcohol Self-Administration.” 2015; 40(6):1549-59.

4. Bollino D, Colunga A, Li B, Aurelian, LA. “ΔPK oncolytic activity includes modulation of the tumour cell milieu.” J Gen Virol. 2016; 97(2):496-508.

5. Aurelian L, Bollino D, Colunga A. “The oncolytic virus ∆PK has multi-modal anti-tumor activity” Pathogens and Disease. 2016; 74(5). pii: ftw050. doi: 10.1093/femspd/ftw050.

6. Webb TJ, Carey GB, East JE, Sun W, Bollino DR, Kimball AS, Brutkiewicz RR. “Alterations in cellular metabolism modulate CD1d-mediated NKT cell responses”. Pathogens and Disease. 2016; 74 (6): ftw055. doi: 10.1093/femspd/ftw055.

7. Shissler SC, Bollino DR, Tiper IV, Bates JP, Derakhshandeh R, Webb TJ. “Immunotherapeutic strategies targeting natural killer T cell responses in cancer.” 2016; 68 (8), 623-638.

8. Bollino D, Webb TJ. Chimeric antigen receptor-engineered natural killer and natural killer T cells for cancer immunotherapy. Trans Res. 2017; 187:32-43.

9. Emadi A, Kapadia B, Bollino D, Bhandary B, Baer MR, Niyongere S, Strovel ET, Kaizer H, Chang E, Choi EY, Ma X, Tighe KM, Carter-Cooper B, Moses BS, Civin CI, Mahurkar A, Shetty AC, Gartenhaus RB, Kamangar F, Lapidus RG. Venetoclax and pegcrisantaspase for complex karyotype acute myeloid leukemia. Leukemia. 2020 Nov 16. doi: 10.1038/s41375-020-01080-6. 

10. Ferraris D, Lapidus R, Truong P, Bollino D, Carter-Cooper B, Lee M, Chang E, LaRossa-Garcia M, Dash S, Gartenhaus R, Choi EY, Kipe O, Lam V, Mason K, Palmer R, Williams E, Ambulos N, Kamangar F, Zhang Y, Kapadia B, Jing Y, Emadi A. Pre-Clinical Activity of Amino-Alcohol Dimeric Naphthoquinones as Potential Therapeutics for Acute Myeloid Leukemia. Anticancer Agents Med Chem. 2021 Jun 2. doi: 10.2174/1871520621666210602131558. 


Research Interests

Targeting glutamine metabolism in hematological and solid neoplasms