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Jacob B. Blumenthal, MD

Academic Title:

Associate Professor

Primary Appointment:


Administrative Title:

Director of the Gerontology Fellowship Program

Additional Title:

Co-Director: GRECC Assessment Clinic, VA Career Development Awardee in Aging


Baltimore VA Medical Center, Room 4B-194

Phone (Primary):

(410) 605-5428


(410) 605-7913

Education and Training

1989: A.B. with Honors, Philosophy, Brown University; Providence, RI         

1994: Doctor of Medicine, Brown University; Providence, RI       

1994-1995: Internship, Internal Medicine, University of Michigan Medical Center; Ann Arbor, MI

1995-1997: Residency, General Internal Medicine, Rhode Island Hospital/Brown University; Providence, RI

1997-2000: Fellowship, Geriatric Medicine, Johns Hopkins University; Baltimore, MD


Dr. Blumenthal is a clinically trained geriatrician and clinical investigator focused on improving the function and quality of older adults with chronic conditions.  Specifically, he studies the biological underpinnings of many age-associated conditionsincluding metabolic dysfunction, changes in body composition, atherosclerosis, and cognitive declineas well as their potential modifiability through lifestyle interventions.  Dr. Blumenthal is also interested in novel models of care delivery that can increase patient access, as well as improve function and quality of life while reducing complications and costs.  He has extensive experience assessing veterans, and through his clinical work has developed a deep appreciation for the importance of addressing functional concerns, with a particular interest in the burdens of medications on older individuals with multiple comorbidities.

Dr. Blumenthal is deeply involved in education, teaching at all levels of the medical school and engaging with trainees from a diverse range of medical professions.  He has mentored a number of students throughout his career and has increased the prominence of Geriatrics on campus.  He has been the Co-Director for the University of Maryland Geriatric Medicine Fellowship and the Baltimore VAMC’s Special Fellowship in Advanced Geriatrics and Aging for more than a decade.  Dr. Blumenthal has also served as Associate Director for Education and Evaluation of the Baltimore Geriatric Research, Education and Clinical Center (GRECC), of which he is currently the Associate Director for Clinical Innovation.

Research/Clinical Keywords

Geriatrics, Function, Metabolism, Safety

Highlighted Publications

Evans WS, Blumenthal JB, Heilman JM, Ryan AS, Prior SJ.  Effects of exercise training with weight loss on skeletal muscle expression of angiogenic factors in overweight and obese older men.  J Appl Physiol (1985). 2021 Jul 1;131(1):56-63. doi: 10.1152/japplphysiol.00084.2021. PMID: 34013746.

Hall RK, Blumenthal JB, Doerfler RM, Chen J, Diamantidis CJ, Jaar BG, Kusek JW, Kallem K, Leonard MB, Navaneethan SD, Sha D, Sondheimer JH, Wagner LA, Wei Y, Zhan M, Fink JC.  Risk of Potentially Inappropriate Medications in Adults with Chronic Kidney Disease.  Am J Kidney Dis. 2021 Dec;78(6):837-845.e1. doi: 10.1053/j.ajkd.2021.03.019. PMID: 34029681.

Addison O, Ryan AS, Blumenthal J, Prior SJ. Increased Intramuscular Adipose Tissue Is Related to Increased Capillarization in Older Adults. J Frailty Aging. 2020;9(3):134-138. doi:10.14283/jfa.2020.20.  PMID: 32588026.

Landers-Ramos RQ, Addison OA, Beamer B, Katzel LI, Blumenthal JB, Robsison S, Hagberg JM, Prior SJ, Circulating Micropartical Concentrations Across Acute and Chronic Cardiovascular Disease Conditions.  Physiol Rep. 2020;8(15):e14534. doi:10.14814/phy2.14534.  PMID:  32748505.

Blumenthal JB, Gitterman A, Ryan AS, Prior SJ. Effects of Exercise Training and Weight Loss on Plasma Fetuin-A Levels and Insulin Sensitivity in Overweight Older Men. J Diabetes Res. 2017; 2017:1492581. doi: 10.1155/2017/1492581. Epub 2017 Jul 9. PubMed PMID: 28770230; PubMed Central PMCID: PMC5523541.

Joseph LJ, Prigeon RL, Blumenthal JB, Ryan AS, Goldberg AP. Weight Loss and Low-Intensity Exercise for the Treatment of Metabolic Syndrome in Obese Postmenopausal Women. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2011; doi: 10.1093/Gerona/glr093.

Susan K. Fried, Thomas Tittelbach, Jacob Blumenthal, Urmila Sreenivasan, Linda Robey, Jamie Yi, Sumbul Khan, Courtney Hollender, Alice S. Ryan and Andrew P. Goldberg. Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian post-menopausal women. Journal of Lipid Research, 2010; 51(5): 1193-200.

Jacob Blumenthal, Ellen Plummer and Steven R. Gambert. Trauma in the Elderly: Causes and Prevention. Clinical Geriatrics, 2010; 18(1): 21-4.

Blumenthal JB, MN Blumenthal. Genetics of Asthma. MedicalClinicsofNorthAmerica 2002;86(5): 937-950. PubMed PMID: 12428539.

Blumenthal JB, R Andersen, B Mitchell, M Seibert, H Yang, H Herzog, B Beamer, S Franckowiak, J Walston. Novel Neuropeptide Y1 and Y5 Receptor Gene Variants’ Associations with Serum Triglyceride and HDL Cholesterol Levels. Clinical Genetics 2002; 62(3): 196-202.

Additional Publication Citations

Serra MC, JB Blumenthal, AS Ryan. Impact of Weight Loss and Aerobic Exercise on Nutrition and Bone Mineral Density in African American and Caucasian Postmenopausal Women. Journal of Aging Research and Clinical Practice 2013: 2(1) 11-16.

Ryan AS, Li G, Blumenthal JB, Ortmeyer HK. Aerobic Exercise + Weight Loss Decreases Skeletal Muscle Myostatin Expression and Improves Insulin Sensitivity in Older Adults. Obesity; 2013: 21 (7) 1350-6.

Yang R, Blumenthal JB, Glynn N, Lee, MJ, Goldberg A, Gong DW, Ryan AS. Decrease in Circulating SAA levels is Correlated with Reduction of Abdominal SAA Secretion During Weight Loss. Obesity; 2014; 22 (4): 1085-90.

Prior SJ, Blumenthal JB, Katzel LI, Goldberg AP, Ryan AS. Increased skeletal muscle capillarization after aerobic exercise training and weight loss predicts improved insulin sensitivity and glucose tolerance in older adults with IGT. Diabetes Care, 2014; 37(5): 1469-75. doi: 10.2337/dc13-2358. Epub 2014 Mar 4. PubMed PMID: 24595633; PubMed Central PMCID: PMC3994928.

Ryan AS, Ge Shealinna, Blumenthal JB, Serra MC, Prior SJ, Goldberg AP. Aerobic Exercise and Weight Loss Reduce Vascular Markers of Inflammation and Improve Insulin Sensitivity in Obese Women. Journal of the American Geriatrics Society, 2014: 62(4): 607-14. doi: 10.2337/db14-1771. Epub 2015 Jun 11. PubMed PMID: 26068543; PubMed Central PMCID: PMC4587640.

Prior SJ, Ryan AS, Blumenthal JB, Watson JM, Katzel LI, Goldberg AP. Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Feb 17. pii: glw017. [Epub ahead of print] PubMed PMID: 26888434.

Fink JC, Doerfler RM, Yoffe MR, Diamantidis CJ, Blumenthal JB, Siddiqui T, Gardner JF, Snitker S, Zhan M. Patient-Reported Safety Events in Chronic Kidney Disease Recorded With an Interactive Voice-Inquiry Dial-Response System: Monthly Report Analysis. J Med Internet Res. 2016 May 26;18(5); e125. doi:10.2196/jmir.5203. PubMed PMID: 27230267.

Lutz AH, Blumenthal JB, Landers-Ramos RQ, Prior SJ. Exercise-induced endothelial progenitor cell mobilization is attenuated in impaired glucose tolerance and type 2 diabetes. J Appl Physiol (1985). 2016 May 19:jap.00349. 2016. doi: 10.1152/japplphysiol.00349.2016. [Epub ahead of print] PubMed PMID: 27197857.

Blumenthal JB, Cai S, May C, Scarinzi G, Gernat E, Mordecai KL, Loreck DJ, Brandt NJ, Inscore AI, Intrator O. Dementia Evaluation, Management and Outreach (DEMO): A Novel Program Improves Access, Satisfaction for Patients with Cognitive Complaints. Federal Practitioner (in press).

Awards and Affiliations

Fellow, American College of Physicians