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Mary-Claire Roghmann, MD, MS

Academic Title:

Professor

Primary Appointment:

Epidemiology & Public Health

Secondary Appointment(s):

Medicine

Administrative Title:

Associate Dean For Trans-Disciplinary Research; Associate Dean For Physician-Scientist Training

Location:

10 S. Pine St., MSTF 336

Phone (Primary):

(410) 706-0062

Phone (Secondary):

(410) 706-0066

Fax:

(410) 706-0098

Education and Training

Dr. Roghmann received her M.D. from the Johns Hopkins University School of Medicine. She then completed her internal medicine residency and infectious disease fellowship at the University of Maryland Medical Center and the Baltimore VA Medical Center. She received her M.S. in Epidemiology and Preventive Medicine from the Department of Epidemiology and Public Health at the University of Maryland School of Medicine.

Biosketch

Dr. Roghmann is an infectious disease physician and clinical investigator. She is a Professor in the Departments of Epidemiology and Public Health and Medicine. She is Associate Dean for Physician Scientist Training and directs the Medical Scientist Training Program (MSTP). In addition, she works closely with the Research Career Development Program in promoting team and collaborative science. She also leads the Research Education Core of our NIH funded Pepper Center. She is also a Research Health Scientist, GRECC Investigator and Staff Physician for the VA Maryland Health Care System.

Research/Clinical Keywords

Antibiotic resistance, Staphylococcus aureus, Cross transmission, Diabetic Foot Infections, Diabetic Foot Ulcers, Prevention, Human microbiome, Clinical research, Molecular epidemiology

Highlighted Publications

Preventing the Transmission of Antibiotic resistant Bacteria in Nursing Homes

  1. Roghmann M, Lydecker L, Mody L, Mullins DC, Onukwugha, E. Strategies to Prevent MRSA Transmission in Community-based Nursing Homes: A Cost Analysis Infect Control Hosp Epidemiol 2016 Aug;37(8):962-6.
  2. Albrecht JS, Croft L, Morgan DJ, Roghmann Perceptions of Gown and Glove Use to Prevent Methicillin-resistant Staphylococcus aureus Transmission in Nursing Homes. J Am Med Dir Assoc. 2016 Sep 24.
  3. Mody L, Roghmann M. Infrequent use of isolation precautions in nursing homes: Implications for an evolving population. J Am Geriatr Soc. 2017 Feb 17. [Editorial]
  4. Pineles L, Morgan DJ, Lydecker A, Johnson JK, Sorkin JD, Langenberg P, Blanco N, Lesse A, Sellick J, Gupta K, Leykum L, Cadena J, Lepcha N, Roghmann M. Transmission of MRSA to Healthcare Worker Gowns and Gloves during Care of Residents in VA Nursing Homes. Am J Infect Control. 2017 Apr 18 pii: S0196-6553(17)30200-6.
  5. Blanco, N, Pineles, L, Lydecker, AD, Johnson, JK, Sorkin, JD, Morgan, JD, the VA Gowns and Gloves Investigators, Roghmann, M. Transmission of resistant Gram-negative bacteria to Healthcare Worker Gowns and Gloves during Care of Nursing Home Residents in VA Community Living Centers. Antimicrob Agents Chemother. 2017 Sep 22;61(10).
  6. Blanco N, Johnson JK, Sorkin JD, Lydecker AD, Levy L, Mody L, Roghmann MC. Transmission of resistant Gram-negative bacteria to Healthcare Personnel Gowns and Gloves during Care of Residents in Community-based Nursing Facilities. Infect Control Hospital Epidemiol. 2018 Dec;39(12):1425-1430.
  7. Jackson SS, Lydecker AD, Magder LS, Roghmann MC. Development and Validation of a Clinical Prediction Rule to Predict Transmission of Methicillin-Resistant Staphylococcus aureus in Nursing Homes. Am J Epidemiol. 2019 Jan 1;188(1):214-221.
  8. Lydecker AD, Osei PA, Pineles L, Johnson JK, Meisel J, Stine OC, Magder L, Gurses AP, Hebden J, Oruc C, Mody L, Jacobs Slifka K, Stone ND, Roghmann MC. Targeted gown and glove use to prevent Staphylococcus aureus acquisition in community-based nursing homes: A pilot study. Infect Control Hosp Epidemiol. 2020 Oct 20:1-7. PMID: 33077004.

Microbiome Studies

  1. Roghmann M, Lydecker, AD, Hittle, L, DeBoy, RT, Nowak, RG, Johnson, JK, Mongodin, EF, Comparison of the Microbiota of Older Adults living in Nursing Homes and the Community. mSphere.  2017 Sep 13;2(5).
  2. Roghmann M, Lydecker AD, Langenberg P, Mongodin EF, Johnson JK. Microbiological effect of mupirocin and chlorhexidine for Staphylococcus aureus decolonization in community and nursing home based adults. Diagn Microbiol Infect Dis. 2017 Feb 13.
  3. Hoffmann D, Palumbo F, Ravel J, Roghmann MC, Rowthorn V, von Rosenvinge E. Improving regulation of microbiota transplants. Science. 2017 Dec 15;358(6369):1390-1391.
  4. Roghmann MC, Lydecker AD, Shardell M, DeBoy RT, Johnson JK, Zhao L, Hittle LL, Mongodin EF. Effect of mupirocin for Staphylococcus aureus decolonization on the microbiome of the nose and throat in community and nursing home dwelling adults. PLoS One. 2021 Jun 8;16(6):e0252004.

Preventing COVID-19 in Nursing Homes

  1. Kim JJ, Coffey KC, Morgan DJ, Roghmann MC. Lessons learned - Outbreaks of COVID-19 in nursing homes. Am J Infect Control. 2020 Oct;48(10):1279-1280. 2020 Jul 31.
  2. Kim JJ, Coffey KC, Morgan DJ, Roghmann MC. Nursing home visitation restrictions during COVID-19-Balancing compassion and safety. Am J Infect Control. 2021 Mar;49(3):407.
  3. Mattingly TJ, Trinkoff, A Lydecker AD, Kim JJ, Yoon JM, Roghmann MC Short-stay admissions associated with large COVID-19 outbreaks in Maryland nursing homes. Gerontology and Geriatric Medicine. Accepted with minor revisions.

Additional Publication Citations

Research Interests

I study antibiotic resistant bacteria with a focus on their transmission or spread. Because of the need to develop nursing home-specific infection control polices and the longer length of stay in this setting, I partner with nursing homes. Our research studies have been translated into practice through new CDC guidance as Enhanced Barrier Precautions (EBP) for emerging MDROs such as pan-resistant bacteria. In the future, the CDC may recommend EBP for all residents with skin breakdown and medical devices in nursing homes moving away from the focus on culture-based precautions.

More recently I have focused on diabetic foot infection, a common cause of amputation in people with diabetes. We are completing recruitment for a randomized double-blinded clinical trial of a topical antiseptic agent for foot hygiene in high-risk Veterans to test whether we can prevent diabetic foot ulcers and their associated infections. I am proud of our research program strives to develop sustainable and reproducible ways to improve the outcomes and quality of life of people at risk for antibiotic resistant infections.

Clinical Specialty Details

Dr. Roghmann is board certified in adult infectious diseases. She attends on infectious disease consult service at the Baltimore VA Medical Center.

Awards and Affiliations

Outstanding Mentor Award (2007), Department of Epidemiology and Preventive Medicine (selected by graduate students), UM SOM

Barnett L. Cohen Award (2012), Maryland Branch of the American Society for Microbiology

Medical School Teaching Award (2013), Department of Epidemiology and Public Health, UM SOM

Alvan R. Feinstein Award (2016-2017), American College of Physicians (ACP)

Grants and Contracts

Dr. Roghmann has been funded by the National Institutes of Health (NIH), Veterans Health Administration Research and Development (VA), Agency for Health Care Research and Quality (AHRQ) and the Centers for Disease Control and Prevention (CDC).

Search for my current funding as PI in NIH Reporter under PI "Roghmann"

In the News

Roghmann, M. Infectious disease expert: here’s how to prevent another coronavirus-like tragedy at nursing homes | COMMENTARY. The Baltimore Sun. May 7, 2020.

Roghmann, M. Follow the Three C's to Reduce COVID-19 Risk. US News. June 30, 2020

Roghmann M. Here’s how to safely visit the elderly during the pandemic | COMMENTARY. The Baltimore Sun. October 15, 2020.

Links of Interest