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Lauren M S. Cohee, MD

Academic Title:

Faculty Member

Primary Appointment:

Pediatrics

Phone (Primary):

(410) 706-8695

Fax:

(410) 706-2999

Education and Training

Dr. Lauren Cohee is an Instructor of Pediatrics and faculty member in the Malaria Research Program in the Center for Vaccine Development and Global Health. She received her medical degree from The Johns Hopkins University School of Medicine. She completed residency training in pediatrics and was a chief resident in the Harriet Lane Pediatric Residency Program at Johns Hopkins Children’s Center. Dr. Cohee completed fellowship training in Infectious Diseases and Tropical Pediatrics as well as a Master's degree in Clinical Research with a focus on Epidemiology at the University of Maryland School of Medicine. 

Biosketch

Dr. Cohee is a pediatric infectious disease specialist, with a primary research interest in malaria and global child health. She has conducted epidemiologic studies of malaria in Malawi since 2011. She is currently an Instructor and is supported by a NIH K23 Career Development Award and a Doris Duke Clinician Scientist Development Award. Her current research focuses on identifying reservoirs of malaria transmission and defining and addressing the burden of malaria in school-age children.

Research/Clinical Keywords

Malaria, Pediatric Infectious Diseases, Global Health, School age children, Neglected Tropical Diseases, Public Health, School Health.

Highlighted Publications

Cohee LM, Opondo C, Clarke SE, Halliday KE, Cano J, Shipper AG, Barger-Kamate B, Djimde A, Diarra S, Dokras A, Kamya MR, Lutumba P, Ly AB, Nankabirwa JI, Njagi JK, Maiga H, Maiteki-Sebuguzi C, Matangila J, Okello G, Rohner F, Roschnik N, Rouhani S, Sissoko MS, Staedke SG, Thera MA, Turner EL, Van Geertruyden JP, Zimmerman MB, Jukes MCH, Brooker SJ, Allen E, Laufer MK, Chico RM. Preventive malaria treatment among school-aged children in sub-Saharan Africa: a systematic review and meta-analyses. Lancet Global Health. 2020 Dec;8(12):e1499-e1511. doi.org/10.1016/S2214-109X(20)30325-9

Cohee LM, Valim C, Coalson JE, Nyambalo A, Chilombe M, Ngwira A, Bauleni A, Seydel KB, Wilson ML, Taylor TE, Mathanga DP, Laufer MK. Potential of school-based preventive treatment to reduce Plasmodium falciparum transmission. Sci Rep. 2021 Mar 25;11(1):6905. doi:10.1038/s41598-021-86450-5

Cohee LM, Nankabirwa JI, Greenwood B, Djimde A, Mathanga DP. Time for malaria control in school-age children. Lancet Child and Adolescent Health. 2021 May 26; PMID: 34051141. https://doi.org/10.1016/S2352-4642(21)00158-9

Cohee LM, Halliday K, Gelli A, Mwenyango I, Lavadenz F, Burbano C, Drake L, Bundy D. The Role of Health in Education and Human Capital: why an integrated approach to school health could make a difference in the futures of schoolchildren in low income countries. American Journal of Tropical Medicine and Hygiene. Nov 2020. doi:10.4269/ajtmh.20-0779

McCann R, Cohee LM, Goupeyou-Youmsi J, Laufer MK. Maximizing Impact: Can Interventions to Prevent Clinical Malaria Reduce Parasite Transmission? Trends in Parasitology. 2020 Sept. doi.org/10.1016/j.pt.2020.07.013

Additional Publication Citations

Yimgang D, Buchwald A, Coalson J, Walldorf J, Bauleni A, Kapito-Tembo A, Taylor TE, Mathanga DP, Laufer MK, Cohee LM. Population attributable fraction of anemia associated with P. falciparum infection in children in Southern Malawi. American Journal of Tropical Medicine and Hygiene. Jan 2021.  doi: 10.4269/ajtmh.20-1120

Peterson I, Kapito-Tembo A, Bauleni A, Nyirenda O, Pensulo P, Still W, Valim C, Cohee L, Taylor T, Mathanga D, Laufer M. Overdiagnosis of malaria illness in an endemic setting: a facility-based surveillance study in Malawi. American Journal of Tropical Medicine and Hygiene. May 3;104(6):2123-30. doi: 10.4269/ajtmh.20-1209

Vareta J, Buchwald AG, Barrall A, Cohee LM, Walldorf JA, Coalson JE, Seydel K, Sixpence A, Mathanga DP, Taylor TE, Laufer MK. Submicroscopic malaria infection is not associated with fever in cross-sectional studies in Malawi. Malar J. 2020 Jun 29;19(1):233. doi: 10.1186/s12936-020-03296-4.

Saito M, Mansoor R, Kennon K, Anvikar AR, Ashley EA, Chandramohan D, Cohee LM, D'Alessandro U, Genton B, Gilder ME, Juma E, Kalilani-Phiri L, Kuepfer I, Laufer MK, Lwin KM, Meshnick SR, Mosha D, Muehlenbachs A, Mwapasa V, Mwebaza N, Nambozi M, Ndiaye JA, Nosten F, Nyunt M, Ogutu B, Parikh S, Paw MK, Phyo AP, Pimanpanarak M, Piola P, Rijken MJ, Sriprawat K, Tagbor HK, Tarning J, Tinto H, Valéa I, Valecha N, White NJ, Wiladphaingern J, Stepniewska K, McGready R, Guérin PJ. Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in pregnancy: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis. BMC Med. 2020 Jun 2;18(1):138. PMID: 32482173

Saito M, Mansoor R, Kennon K, Anvikar AR, Ashley EA, Chandramohan D, Cohee LM, D'Alessandro U, Genton B, Gilder ME, Juma E, Kalilani-Phiri L, Kuepfer I, Laufer MK, Lwin KM, Meshnick SR, Mosha D, Muehlenbachs A, Mwapasa V, Mwebaza N, Nambozi M, Ndiaye JA, Nosten F, Nyunt M, Ogutu B, Parikh S, Paw MK, Phyo AP, Pimanpanarak M, Piola P, Rijken MJ, Sriprawat K, Tagbor HK, Tarning J, Tinto H, Valéa I, Valecha N, White NJ, Wiladphaingern J, Stepniewska K, McGready R, Guérin PJ. Efficacy and tolerability of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a systematic review and individual patient data meta-analysis. Lancet ID. 2020 Apr. doi.org/10.1016/S1473-3099(20)30064-5

Andronescu LR, Buchwald AG, Coalson JE,Cohee L, Bauleni A, Walldorf JA, Kandangwe C, Mzilahowa T, Taylor TE, Mathanga DP, Laufer MK. Net age, but not integrity, may be associated with decreased protection against Plasmodium falciparum infection in southern Malawi. Malaria Journal. 2019 Sep 24;18(1): PMID: 31551076

Coalson JE, Cohee LM, Walldorf JA, Bauleni A, Mathanga DP, Taylor TE, Wilson ML, Laufer MK. Challenges in treatment for fever among school-age children and adults in Malawi. American Journal of Tropical Medicine and Hygiene. 2019 Feb;100(2):287-295. PMID:30526747

Cohee LM, Chilombe M, Ngwira A, Jemu S, Mathanga DP, Laufer MK. Pilot study of the addition of mass treatment for malaria to existing school-based programs to treat neglected tropical diseases. Am J Trop Med Hyg. 2018 Jan;98(1):95-99. PMID: 29141763. 

Cohee LMLaufer MK. Tackling malaria transmission in sub-Saharan Africa. Lancet Global Health.2018 Jun;6(6):e598-599. PMID: 29661636.

Coalson JE, Cohee LM, Buchwald AG, Nyambalo A, Kubale J, Seydel KB, Mathanga D, Taylor TE, Laufer MK, Wilson ML. Simulation models predict that school-age children are responsible for most human-to-mosquito Plasmodium falciparum transmission in southern Malawi. Malaria Journal. 2018 Apr 3;17(1):147. PMID: 29615044; PMCID: PMC5883608.

Cohee LM, Laufer MK. Malaria in Children. Pediatr Clin North Am. 2017;64(4):851-866. Pubmed PMID: 28734514

Buchwald AG, Coalson JE, Cohee LM, Walldorf JA, Chimbiya N, Bauleni A, Nkanaunena K, Ngwira A, Sorkin JD, Mathanga DP, Taylor TE, Laufer MK. Insecticide-treated net effectiveness at preventing Plasmodium falciparum infection varies by age and season. Malar J. 2017 Jan 17;16(1):32. PubMed PMID: 28095916; PubMed Central PMCID: PMC5240228.

Coalson JE, Walldorf JA, Cohee LM, Ismail MD, Mathanga D, Cordy RJ, Marti M, Taylor TE, Seydel KB, Laufer MK, Wilson ML. High prevalence of Plasmodium falciparum gametocyte infections in school-age children using molecular detection: patterns and predictors of risk from a cross-sectional study in southern Malawi. Malar J. 2016 Nov 4;15(1):527. PubMed PMID: 27809907; PubMed Central PMCID: PMC5096312.

Buchwald AG, Walldorf JA, Cohee LM, Coalson JE, Chimbiya N, Bauleni A, Nkanaunena K, Ngwira A, Kapito-Tembo A, Mathanga DP, Taylor TE, Laufer MK. Bed net use among school-aged children after a universal bed net campaign in Malawi. Malar J. 2016 Feb 29;15:127. PubMed PMID: 26928321; PubMed Central PMCID: PMC4770676.

Boudová S, Divala T, Mawindo P, Cohee L, Kalilani-Phiri L, Thesing P, Taylor TE, Laufer MK. The prevalence of malaria at first antenatal visit in Blantyre, Malawi declined following a universal bed net campaign. Malar J. 2015 Oct 29;14:422. PubMed PMID: 26510414; PubMed Central PMCID: PMC4625940.

Walldorf JA, Cohee LM, Coalson JE, Bauleni A, Nkanaunena K, Kapito-Tembo A, Seydel KB, Ali D, Mathanga D, Taylor TE, Valim C, Laufer MK. School-Age Children Are a Reservoir of Malaria Infection in Malawi. PLoS One. 2015 Jul 24;10(7):e0134061. PubMed PMID: 26207758; PubMed Central PMCID: PMC4514805.

Boudová S, Cohee LM, Kalilani-Phiri L, Thesing PC, Kamiza S, Muehlenbachs A, Taylor TE, Laufer MK. Pregnant women are a reservoir of malaria transmission in Blantyre, Malawi. Malar J. 2014 Dec 17;13:506. PubMed PMID: 25520145; PubMed Central PMCID: PMC4301453.

Cohee LM, Kalilani-Phiri L, Mawindo P, Joshi S, Adams M, Kenefic L, Jacob CG, Taylor TE, Laufer MK. Parasite dynamics in the peripheral blood and the placenta during pregnancy-associated malaria infection. Malar J. 2016 Sep 21;15(1):483. PubMed PMID: 27653788; PubMed Central PMCID: PMC5031282.

Cohee LM, Kalilani-Phiri L, Boudova S, Joshi S, Mukadam R, Seydel KB, Mawindo P, Thesing P, Kamiza S, Makwakwa K, Muehlenbachs A, Taylor TE, Laufer MK. Submicroscopic malaria infection during pregnancy and the impact of intermittent preventive treatment. Malaria Journal.2014 13:274. PMCID: PMC4110536.

Cohee LM, Crocetti MT,Sabath B, Kapoor S, Serwint JR. Ethnic differences in parental perceptions and management of childhood fever. Clinical Pediatrics.2010 Apr; 49(3):221-7. PMID: 19448132.

Cohee L, Mills LA, Kagaayi J, Jacobs I, Galiwango R, Ludigo J, Ssekasanvu J, Reynolds SJ. High retention and appropriate use of insecticide-treated nets distributed to HIV-affected households in Rakai, Uganda: results from interviews and home visits. Malar J. 2009 Apr 22;8:76. PubMed PMID: 19383173; PubMed Central PMCID: PMC2675534.

Washington CH, Singer LM, McCaig T, Tikoduadua L, Ali ST, Fong J, Luveni J, Kyaw-Myint TO, Watson S, Russell F.  High perinatal transmission rate of Human Immunodeficiency Virus in Fiji.  Papua New Guinea Medical Journal. 2008 Mar-June; 51(1-2): 56-9. PMID: 19999310.

Singer LM, Newman RD, Diarra A, Moran AC, Huber CS, Stennies G, Sirima SB, Konate A, Yameogo M, Sawadogo R, Barnwell JW, Parise ME. Evaluation of a malaria rapid diagnostic test for assessing the burden of malaria during pregnancy. Am J Trop Med Hyg. 2004 May;70(5):481-5. PubMed PMID: 15155979.

Singer LM, Mirel LB, ter Kuile FO, Branch OH, Vulule JM, Kolczak MS, Hawley WA, Kariuki SK, Kaslow DC, Lanar DE, Lal AA. The effects of varying exposure to malaria transmission on development of antimalarial antibody responses in preschool children. XVI. Asembo Bay Cohort Project. J Infect Dis. 2003 Jun 1;187(11):1756-64. PubMed PMID: 12751033.

Awards and Affiliations

Alpha Omega Alpha

Early Career Award, Thrasher Research Fund

Fellow Award, Pediatric Infectious Diseases Society

Postdoctoral Fellowship in Tropical Infectious Diseases, Burroughs Wellcome Fund/American Society of Tropical Medicine and Hygiene

Doris Duke Clinician Scientist Development Award

Grants and Contracts

NIH/NIAID K23 Career Development Award "Impact of P. falciparum diversity on transmission reducing immunity"

Doris Duke Charitable Foundation Clinician Scientist Development Award "Clinical trial to evaluate Intermittent Screening and Treatment with high sensitivity aapid diagnostic tests and Intermittent Preventive Treatment of malaria in asymptomatic schoolchildren to decrease P. falciparum infection and transmission"