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Bingren Hu, PhD

Academic Title:

Professor

Primary Appointment:

Anesthesiology

Secondary Appointment(s):

Neurology

Location:

MSTF, 5-34D

Phone (Primary):

(410) 706-5666

Fax:

(410) 706-2550

Education and Training

1983 Bachelor of Medicine (MB), Bethune University of Medical Sciences, China

1989 MD, Bethune University of Medical Sciences, China

1993 PhD, Neurochemistry, Lund University, Lund, Sweden

1993-1995 Postdoctoral Research Fellowship
Laboratory for Experimental Brain Research
University of Lund, Lund, Sweden

Highlighted Publications

1.    Liu CH, Gao Y, Barrett J, and BR Hu (2010) Protein aggregation and autophagy after brain ischemia. J  
       Neurochem. 115:68-78.
2.    Luo T, Park Y, Sun X, Liu C, Hu BR (2013) Protein misfolding, aggregation, and autophagy after brain ischemia.
       Translational Stroke Research. 4:581-288.
3.    Park Y, Luo T, Zhang F, Liu C, Bramlett HM, Dietrich WD, Hu BR (2013) Downregulation of Src-kinase and glutamate-
       receptor phosphorylation after traumatic brain injury. J Cereb Blood Flow Metab. 33:1642-1649.
4.    Zhang F, Guo A, Liu C, Comb M, Hu BR (2013) Phosphorylation and assembly of glutamate receptors after
       brain ischemia. Stroke 44:170-176
5.    Sun X, Crawford R, Liu C, Luo T, Hu BR (2015) Development Dependent Regulation of Molecular Chaperones after
       Hypoxia-Ischemia. Neurobiol Dis. 82:123-131.

Research Interests

Bingren Hu, MD, PhD, is a Professor in Trauma in the Department of Anesthesiology. Dr. Hu’s laboratory main research interests include molecular mechanisms and treatments of brain ischemia, traumatic brain injury, and hemorrhagic shock. In brain ischemia research, his laboratory employs both global and focal ischemia, and neonatal hypoxia-ischemia rat and mouse models to study protein misfolding and aggregation, membrane trafficking, the protein degradation pathways, and novel therapeutics against ischemia-reperfusion brain injury.  In traumatic brain injury research, his laboratory employs a rat fluid percussion injury model to investigate aberrant synaptogenesis and post-TBI seizures. In hemorrhagic shock research, his laboratory employs rat lethal hemorrhagic shock models to investigate mechanisms and treatment of ischemia reperfusion injury due to lethal hemorrhagic shock in the brain, spinal cord, and abdominal organs.