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Scott E. Devine, PhD

Academic Title:

Associate Professor

Primary Appointment:

Medicine

Location:

Biopark II, 615

Phone (Primary):

(410) 706-2343

Education and Training

1987-1993: Doctor of Philosophy, Molecular and Cell Biology, University of Maryland, Baltimore
1993-1999: Postdoctoral Fellow, Johns Hopkins University School of Medicine

Biosketch

Scott Devine is a faculty member at the Institute for Genome Sciences (IGS) and an Associate Professor of Medicine at the University of Maryland School of Medicine in Baltimore, Maryland. He is primarily interested in human genome variation and how such variation affects human health.

Employment

2000-2009: Assistant Professor, Emory University School of Medicine
2009-present: Associate Professor, Dept. of Medicine and Institute for Genome Sciences, University of Maryland School of Medicine
2011-present: Genome Biology Track Leader, Molecular Medicine Graduate Program

Research/Clinical Keywords

Human genome; genetic variation; mobile genetic elements

Highlighted Publications

Scott, E.C., Gardner, E.J., Masood, A., Chuang, N.T., Vertino, P.M., and Devine, S.E. (2016).  A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. Genome Res. 26, 745-755. (Cover article).

Sudmant, P.H.*, Raush, T.*, Gardner, E.J.*, Handsaker, R.E.*, Abyzov, A.*, Huddleston, J.*, Zhang, Y.*, Ye, K.*, Jun, G., His-Yang Fritz, M., Konkel, M.K., Malhotra, A., Stutz, A.M., Shi, X., Paolo, Casale, F., Chen, J., Hormozdiari, F., Dayama, G., Chen, K., Malig, M., Chaisson, M.J., Walter, K., Meiers, S., Kashin, S., Garrison, E., Auton, A., Lam, H.Y., Jasmine Mu, X., Alkan, C., Antaki, D., Bae, T., Cerveira, E., Chines, P., Chong, Z., Clarke, L., Dal, E., Ding, L., Emery, S., Fan, X., Gujral, M., Kahveci, F., Kidd, J.M., Kong, Y., Lameijer, E.W., McCarthy, S., Flicek, P., Gibbs, R.A., Marth, G., Mason, C.E., Menelaou, A., Muzny, D.M., Nelson, B.J., Noor, A., Parrish, N.F., Pendleton, M., Quitadamo, A., Raeder, B., Schadt, E.E., Romanovitch, M., Schlattl, A., Sebra, R., Shabalin, A.A., Untergasser, A., Walker, J.A., Wang, M., Yu, F., Zhang, C., Zhang, J., Zheng-Bradley, X., Zhou, W., Zichner, T., Sebat, J., Batzer, M.A., McCarroll, S.A., 1000 Genome Project Consortium, Mills, R.E.#, Gerstein, M.B.#, Bashir, A.#, Stegle, O.#, Devine, S.E.#, Lee, C.#, Eichler, E.E.#, and Korbel, J.O.# (2015).  An integrated map of structural variation in 2,504 human genomes.  Nature 526, 75-81.   * Joint First Authors.  # Joint senior authors.

The 1000 Genomes Project Consortium (including Devine, S.E.) (2015) A global reference for human genetic variation.  Nature 526, 68-74.

The 1000 Genomes Project Consortium (including, Devine, S.E.) (2012) An integrated map of genetic variation from 1,092 human genomes.  Nature 491, 56-65.  

Mills, R.E., Pittard, W.S., Mullaney, J.M., Farooq, U., Creasy, T.H., Mahurkar, A.A., Kemeza, D.M., Strassler, D.S., Ponting, C.P., Webber, C., and Devine, S.E. (2011) Natural genetic variation caused by small insertions and deletions in the human genome.  Genome Res. 21, 830-839.

Iskow, R.C., McCabe, M.T., Mills, R.E., Torene, S., Van Meir, E.G., Vertino, P.M., and Devine, S.E. (2010) Natural mutagenesis of human genomes by endogenous retrotransposons. Cell 141, 1253-1261.

Links of Interest

Mobile Element Locator Tool (MELT) download site, documentation, Google chat:  http://melt.igs.umaryland.edu