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Sarah A. Schmalzle, MD

Academic Title:

Associate Professor

Primary Appointment:


Administrative Title:

Chief, Center of Infectious Disease Ambulatory Practice

Additional Title:

Medical Director of The THRIVE Program; Medical Director of the Center for Infectious Disease


IHV Rm. N147

Phone (Primary):




Education and Training

Medical School- Sidney Kimmel (formerly Jefferson) Medical College of Thomas Jefferson University
Residency- University of Maryland Medical Center
Fellowship- University of Maryland Medical Center


Sarah Schmalzle is an Associate Professor in the Department of Internal Medicine, Division of Infectious Disease. She is the medical director of the THRIVE program of the Institute of Human Virology at the University of Maryland School of Medicine, which provides primary and HIV specialty care for approximately 2500 people living with HIV. She sees outpatients for HIV care and prevention, hepatitis C, and general infectious diseases and attends on the inpatient Med-ID services. She has previously held the roles of associate program director for the internal medicine residency program at the Midtown Campus, and for the infectious disease fellowship. Areas of academic interest include HIV prevention, HIV primary care, models of care in older adults with HIV, opportunistic infections, and infections in people who inject drugs.

Research/Clinical Keywords

HIV primary care, HIV prevention, HIV in older adults, infections in people who inject drugs, medical education, antimicrobial stewardship, penicillin allergy testing

Highlighted Publications

Dickinson SA, Fantry LE. Use of Dual-Energy Absorptiometry (DXA) in HIV-Infected Patients. J Int Assoc Physicians AIDS Care. 2012;11(4):239-44.

Schmalzle SA, Buchwald UK, Gilliam BL, Riedel DJ. Cryptococcus neoformans Infection in Malignancy. Mycoses 2016. doi: 10.1111/myc.12496

Heil E, Bork J, Schmalzle SA, Kleinberg M, Kewalramani A, Gilliam B, Buchwald, U. Implementation of an Infectious Disease Fellow Managed Penicillin Allergy Skin Testing Service. Open Forum Infect Dis 2016. doi: 10.1093/ofid/ofw155

Schmalzle SA, Tabatabai A, Mazzeffi M, Matta A, Hollis A, Zubrow M, Rajagopal K, Thom K, Scalea T. Recreational ‘mud fever’: Leptospira interrogans induced diffuse alveolar hemorrhage and severe acute respiratory distress syndrome in a U.S. Navy seaman following ‘mud-run’ in Hawaii. IDCases 2019. 15:e00529. Doi: 10.1016/j.idcr.2019.e00529.

Sameed M, Nwaiser C, Bhandari P, Schmalzle SA. Meropenem Induced Stevens Johnson Syndrome / Toxic Epidermal Necrolysis in a Patient with Known Type-IV Penicillin Hypersensitivity. BMJ Case Rep 2019;12:e230144.

Deming M, MarkA, Nyemba V, Schmalzle SA. Cognitive Biases And Knowledge Deficits Leading To Delayed Recognition Of Cryptococcal Meningitis. IDCases 2019;

Sowah LA, Schmalzle SA, Khambaty M, Buchwald U. Establishing an Anal Cancer Screening Program in an Outpatient HIV Clinic: Referral Patterns and Patient Perceptions Survey. J Int Assoc Provid AIDS Care 2020; org/10.1177/2325958219899530.

Hauser N, Kim JJ, Leuthy PM, Bork J, Schmalzle SA. Multicenter Retrospective Cohort Study of the Clinical Significance of Staphylococcus lugdunensis Isolated from a Single Blood Culture Set. Diagnostic Microbiol Infect Dis 2020;99(3):115261.

Ajaka, L.; Heil, E.; Schmalzle, S. Dalbavancin in the Treatment of Bacteremia and Endocarditis in People with Barriers to Standard Care. Antibiotics 2020;9:700.

Rebechi MT, Heil EL, Luethy PM, Schmalzle SA. Streptococcus pyogenes Infective Endocarditis – Association with Injection Drug Use: Case Series and Review of the Literature. Open For Infect Dis 2021;8(6);

Kamkwalala AR, Garg A, Roy U, Matthews A, Castillo-Mancilla J, Lake J, Sebastiani G, Yin M, Brown TT, Kamer A, Jabs D, Ellis R, Boffito M, Greene M, Schmalzle SA, Siefler, E, Erlandson K, Moore DJ. Current Considerations for Clinical Management and Care of People with HIV: Findings presented at the 11th International Workshop on HIV and Aging. AIDS Res Human Retrovir In Press.

Davis AJ, Greene M, Siefler E, Fitch KV, Schmalzle SA, Krain A, Vera J, Boffito M, Falutz J, Erlandson KM. Strengths and Challenges of Various Models of Geriatric Consultation for Older Adults Living with HIV. Clin Infect Dis 2021; ciab682,

Schmalzle SA, Hanes D, Taylor G. Clinical course of human monkeypox infection in a renal transplant recipient living with HIV. Transplant Infect Dis 2022;

Traver EC, Heil EL, Schmalzle SA. Linezolid in combination with methadone or buprenorphine rarely causes serotonin toxicity: a cross-sectional analysis and review of the literature. Open For Inf Dis 2022;