August 24, 2022 | Heide Aungst
Monday, July 18, 2022
New Genomic Research Shows Why Testing Malaria Vaccines in the Clinic is as Rigorous as Natural Exposure in the Field
Malaria is the deadliest mosquito-borne parasitic infection of humans. In 2021, after a century of research, the World Health Organization (WHO) approved the world’s first malaria vaccine. That vaccine reduces the incidence of malaria infections in young children aged 5-17 months by only 30 percent, meaning that it remains critical to continue developing and testing more effective vaccines.
Thursday, March 18, 2021
UM School of Medicine Helps Maryland Conduct State-Wide Sequencing of Variants in Positive COVID-19 Test Specimens
In an effort to monitor the spread of COVID-19 variants in the State of Maryland, University of Maryland School of Medicine (UMSOM) Dean E. Albert Reece, MD, PhD, MBA, announced that UMaryland Genomics at UMSOM will perform genome sequencing of variants in at least 10 percent of COVID-19 test samples, reaching an important benchmark set by the federal government to help control the spread of these variants.
Thursday, February 25, 2021
UM School of Medicine Researchers Participate in Landmark Study Detailing Sequencing of Full Human Genomes to Better Capture Genetic Diversity
Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes. This reference data includes individuals from around the world and better captures the genetic diversity of the human species. Among other applications, the work will enable population-specific studies on genetic predispositions to human diseases as well as the discovery of more complex forms of genetic variation.
Wednesday, February 26, 2020
Researchers Develop First Catalogue of Genes that Comprise Community of Microbes in Vaginal Microbiome
University of Maryland School of Medicine’s (UMSOM) Institute for Genome Sciences (IGS) researchers have created the first catalogue of genes that comprise the community of microbes, which inhabit the human vagina. The catalogue, called human vaginal non-redundant gene catalog (VIRGO), was recently released as a public resource that can be used by researchers to facilitate a more in-depth understanding of the role of vaginal microorganisms in women’s health and to potentially develop future treatments for certain gynecologic conditions.
Tuesday, December 03, 2019
UM School of Medicine Researchers Institute for Genome Sciences' Researchers Discover Potential New Treatment for Tropical Parasitic Disease Using Genomics
Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine (UMSOM) Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat. The potential new therapy is an experimental cancer drug called JQ1 and targets proteins found prominently in the worm’s genome; it appears to effectively kill the adult worms in a laboratory setting, according to the study which was published today in the journal mSystems.
Wednesday, May 25, 2016
A University of Maryland School of Medicine researcher has helped develop an innovative computing technique that, on very large amounts of data, is both faster and more accurate than current methods. To spur research, a program using this technique is being offered for free to the biomedical research community.