October 18, 2019 | Deborah Kotz
Department of Anesthesiology
(410) 328-6120 (phone)
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Director of Media Relations
Office of Public Affairs & Communications
University of Maryland School of Medicine
Friday, October 07, 2022
Other SARS-CoV-2 Proteins are Important for Disease Severity, Aside from the Spike
University of Maryland School of Medicine researchers have identified how multiple genes of SARS-CoV-2 affect disease severity, which could lead to new ways in how we develop future vaccines or develop newer treatments. The genes control the immune system of the host, contributing to how fiercely the body responds to a COVID-19 infection.
Wednesday, February 16, 2022
Study Shows New Drug Combination More Effective Against SARS-CoV-2
Researchers at the University of Maryland School of Medicine (UMSOM) and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19. The researchers showed that combining the experimental drug brequinar with either of the two drugs already approved by the U.S. Food and Drug Administration for emergency use, remdesivir or molnupiravir, inhibited growth of the SARS-CoV-2 virus in human lung cells and in mice. Their findings suggest that these drugs are more potent when used in combination than individually.
Friday, February 05, 2021
UM School of Medicine Researchers Demonstrate Strong Immune Response for New COVID-19 Vaccine in Pre-Clinical Tests
Researchers at the University of Maryland School of Medicine (UMSOM) have found promising results in pre-clinical studies for a new experimental vaccine against COVID-19 made by Novavax. The vaccine was found to generate a robust immune response in animals exposed to the vaccine with strong data indicating safety and efficacy, according to the study published recently in the journal Nature Communications. The results have been used to begin testing the vaccine in human trials in the U.S. with a Phase 3 trial that recently launched at the UMSOM’s Center for Vaccine Development and Global Health.
Tuesday, June 16, 2020
UM School of Medicine Researchers Receive Federal Funding to Rapidly Test New Treatments for COVID-19
Researchers at the University of Maryland School of Medicine (UMSOM) will be partnering on an agreement funded by the federal government’s Defense Advanced Research Projects Agency (DARPA) to rapidly test hundreds of drugs, approved and marketed for other conditions, to see whether any can be repurposed to prevent or treat COVID-19. The compounds will be tested in studies using state-of-the-art technologies in the laboratory of coronavirus researcher Matthew Frieman, PhD., Associate Professor of Microbiology and Immunology at the University of Maryland School of Medicine. UMSOM will receive up to $3.6 million over the next year to fund this effort.
Monday, June 15, 2020
UM School of Medicine Researchers Help Identify Potent Antibody Cocktail with Potential to Treat COVID-19
Researchers at the University of Maryland School of Medicine (UMSOM) evaluated several human antibodies to determine the most potent combination to be mixed in a cocktail and used as a promising anti-viral therapy against the virus that causes COVID-19. Their research, conducted in collaboration with scientists at Regeneron Pharmaceuticals, was published today in the journal Science. The study demonstrates the rapid process of isolating, testing and mass-producing antibody therapies against any infectious disease by using both genetically engineered mice and plasma from recovered COVID-19 patients.
Tuesday, August 13, 2019
Researchers Identify How Vaginal Microbiome Can Elicit Resistance or Susceptibility to Chlamydia
The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections (STIs) in developed countries. New research by the University of Maryland School of Medicine (UMSOM) shows how the microbiome can either protect or make a woman more susceptible to these serious infections.
Friday, September 14, 2018
Nationwide Research on African-American Kidneys Hopes to Unravel Genetic Variation That Increases Disease Risk
With African-Americans developing kidney failure at rates four to five times higher than Americans of European descent, a groundbreaking nationwide study will track nearly every African-American donor kidney over the next five years.
Thursday, March 22, 2018
With Big Data, Researchers Identify New Targets for Lung Disease Treatments
Every year, approximately 12 million adults in the U.S. are diagnosed with Chronic Obstructive Pulmonary Disease (COPD), and 120,000 die from it. For people with COPD, Haemophilus influenzae, a bacterium, can be particularly dangerous.
Tuesday, December 19, 2017
UMSOM Scientists Identify Key Factors that Help Microbes Thrive in Harsh Environments
Three new studies by University of Maryland School of Medicine (UMSOM) scientists have identified key factors that help microbes survive in harsh environments.
Tuesday, December 06, 2016
Researchers Combine MERS and Rabies Viruses to Create Innovative 2-For-1 Vaccine
In a new study, University of Maryland School of Medicine (UM SOM) researchers have modified a rabies virus, so that it has a protein from the MERS virus; this altered virus works as a 2-for-1 vaccine that protects mice against both Middle East Respiratory Syndrome (MERS) and rabies.