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Mark A. Travassos, MD, MSc

Academic Title:

Assistant Professor

Primary Appointment:

Pediatrics

Secondary Appointment(s):

Medicine

Location:

HSF-I, 480

Phone (Primary):

(410) 706-8695

Fax:

(410) 706-6205

Education and Training

  • A.B.,Biology, Harvard University 
  • MSc, Biology, Universityof Oxford
  • M.D., Cornell University Medical College
  • Pediatric residency, International Health Track, Rainbow Babies and Children's Hospital
  • Fellowship, Pediatric Infectious Diseases and Tropical Pediatrics, University of Maryland School of Medicine

Biosketch

Dr. Travassos is a pediatric infectious diseases specialist and member of the Institute for Global Health's Division of Malaria Research. His research focuses on malaria pathogenesis and epidemiology, with a focus on cerebral malaria and other forms of severe malaria. This includes study of:

  • Malaria parasite variant surface antigens and their contribution to the development of cerebral malaria
  • How children with sickle cell trait are protected against illness from malaria
  • The development of natural protective immunity to malaria in malaria-endemic regions

Dr. Travassos co-directs the Immunoepidemiology and Pathogenesis Unit of the Malaria Research Program with Dr. Andrea Berry.

Dr. Travassos' research also includes work in Ethiopia assessing vaccine coverage trhough the use of serosurveys.

 

 PhD students:

 
 

 

Research/Clinical Keywords

cerebral malaria, severe malaria, immunity, genomic epidemiology, immunoepidemiology, pathogenesis, microarray

Highlighted Publications

  1. Zhou AE, Berry AA, Bailey JA, Pike 1, Dara A, Agrawal S, Stucke EM, Ouattara A, Coulibaly D, Lyke KE, Laurens MB, Adams M, Takala-Harrison S, Pablo J, Jasinskas A, Nakajima R, Niangaly A, Kouriba B, Kone AK, Rowe JA, Doumbo OK, Thera MA, Patel JJ, Tan JC, Felgner PL, Plowe CV, Travassos MA. Antibodies to peptides in semiconserved domains of RIFINs and STEVORs correlate with malaria exposure. mSphere 2019 Mar 20;4(2). pii: e00097-19. doi: 10.1128/mSphere.00097-19. PMID: 30894432.
  2. Travassos MA, Niangaly A, Bailey JA, Ouattara A, Coulibaly D, Lyke KE, Laurens MB, Pablo J, Jasinskas A, Nakajima R, Berry AA, Adams M, Jacob CG, Pike A, Takala-Harrison S, Liang L, Kouriba B, Kone AK, Rowe JA, Moulds J, Diallo DA, Doumbo OK, Thera MA, Felgner PL, Plowe CV.  Children with cerebral malaria or severe malarial anaemia lack immunity to distinct variant surface antigen subsets. Scientific Reports. 2018 Apr 19;8(1):6281. doi: 10.1038/s41598-018-24462-4. PMID: 29674705.
  3. Travassos MA, Beyene B, Adam Z, Campbell JD, Mulholland N, Diarra SS, Kassa T, Oot L, Sequeira J, Reymann M, Blackwelder WC, Wu Y, Ruslanova I, Goswami J, Sow SO, Pasetti MF, Steinglass R, Kebede A, & Levine MM. Immunization Coverage Surveys and Linked Biomarker Serosurveys in Three Regions in Ethiopia. PLoS One: (2016);11(3):e0149970. PMID: 26934372.
  4. Travassos MA, Beyene B, Adam Z, Campbell JD, Mulholland N, Diarra SS, Kassa T, Oot L, Sequeira J, Reymann M, Blackwelder WC, Pasetti MF, Sow SO, Steinglass R, Kebede A, & Levine MM. Strategies for Coordination of a Serosurvey in Parallel with an Immunization Coverage Survey. American Journal of Tropical Medicine & Hygiene: (2015 Aug); 93(2): 426-424. PMID: 26055737.
  5. Travassos MA, Coulibaly D, Laurens MB, Dembélé A, Tolo Y, Koné AK, Traoré K, Niangaly A, Guindo A, Wu Y, Berry AA, Jacob CG, Takala-Harrison S, Adams M, Shrestha B, Mu AZ, Kouriba B, Lyke KE, Diallo DA, Doumbo OK, Plowe CV, & Thera MA. Hemoglobin C trait provides protection from clinical falciparum malaria in Malian children. Journal of Infectious Diseases: (2015 Dec 1); 212(11): 1778-1786. PMID: 26019283.
  6. Travassos MA, Coulibaly D, Bailey JA, Niangaly A, Adams M, Nyunt MM, Ouattara A, Lyke KE, Laurens MB, Pablo J, Jasinskas A, Nakajima R, Berry AA, Takala-Harrison S, Kone AK, Kouriba B, Rowe JA, Doumbo OK, Thera MA, Laufer MK, Felgner PL, & Plowe CV. Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women. American Journal of Tropical Medicine & Hygiene: (2015 Jun); 92(6): 1190-1194. PMID: 25918203.
  7. Travassos MA, Niangaly A, Bailey JA, Ouattara A, Coulibaly D, Laurens MB, Pablo J, Jasinskas A, Nakajima-Sasaki R, Berry AA, Takala-Harrison S, Kouriba B, Rowe JA, Lyke KE, Doumbo OK, Thera MA, Felgner PL, & Plowe CV. Seroreactivity to the PfEMP1 intracellular domain in malaria-exposed children and adults. Journal of Infectious Diseases (2013 Nov 1); 208(9):1514-9. PMID: 23901079.