October 31, 2023 | Deborah Kotz
Senior Director of Media Relations
Office of Public Affairs & Communications
University of Maryland School of Medicine
Friday, September 22, 2023
UM Medicine Faculty-Scientists and Clinicians Perform Second Historic Transplant of Pig Heart into Patient with End-Stage Cardiovascular Disease
A 58-year-old patient with terminal heart disease became the second patient in the world to receive a historic transplant of a genetically-modified pig heart on September 20. He is recovering and communicating with his loved ones. This is only the second time in the world that a genetically modified pig heart has been transplanted into a living patient. Both historic surgeries were performed by University of Maryland School of Medicine (UMSOM) faculty at the University of Maryland Medical Center (UMMC).
Friday, June 30, 2023
Lessons Learned from World’s First Successful Transplant of Genetically-Modified Pig Heart into Human Patient
A new study published today in the Lancet has revealed the most extensive analysis to date on what led to the eventual heart failure in the world's first successful transplant of a genetically-modified pig heart into a human patient. This groundbreaking procedure was conducted by University of Maryland School of Medicine (UMSOM) physician-scientists back in January 2022 and marked an important milestone for medical science.
Friday, December 16, 2022
UM School of Medicine Surgeon-Scientist Named One of Nature’s 10 People Who Helped Shape the Science Stories of 2022
The world-renowned journal Nature, named Muhammad Mohiuddin, MD, DSc, Program and Scientific Director of the Cardiac Xenotransplantation Program at the University of Maryland School of Medicine (UMSOM), on its annual list of 10 people who helped shaped science in 2022. His pivotal work over the past three decades transplanting genetically-modified pig hearts into non-human primates led to the historic xenotransplant of a pig heart into a human patient this past January. The surgery was led by Bartley Griffith, MD, the Thomas E. and Alice Marie Hales Distinguished Professor of Transplant Surgery and Clinical Director of the Cardiac Xenotransplantation Program, who was also recognized by Nature for his ground-breaking efforts to move the field of transplantation into a new era.
Monday, November 14, 2022
Ten months after transplanting the first genetically-modified pig heart into a human patient, University of Maryland School of Medicine (UMSOM) researchers continue to report on new findings from the landmark transplant. Their latest study demonstrates for the first time that unexpected electrical changes occurred in the pig heart transplanted into the patient David Bennett. The findings were presented at the American Heart Association (AHA) meeting this past weekend.
Wednesday, June 22, 2022
University of Maryland School of Medicine Faculty Scientists and Clinicians Publish Findings of World’s First Successful Transplant of Genetically Modified Pig Heart into Human Patient
Six months ago, University of Maryland School of Medicine surgeon-scientists successfully implanted a genetically modified pig heart into a 57 year-old patient with terminal heart disease in a first-of-its-kind surgery. It was considered an early success because the patient lived for two months with a strong functioning heart showing no obvious signs of rejection, according to a new paper published today in the New England Journal of Medicine.