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Center for Vaccine Development & Global Health (CVD)
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Maternal and Child Health

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Maternal and Child Health

An estimated 5 million children under the age of 5, including 2.3 million newborns, die each year. From its inception, the health of mothers and their children have been a consistent thread in all the work at CVD. Our dedicated faculty and staff are committed to understanding the nuances of immune responses in children and designing and conducting clinical trials for pediatric participants. The Center partners with two local pediatric clinics to conduct pediatric vaccine trials. Nearly every vaccine currently recommended for children in the US has been tested by our team. Additionally, our faculty collaborate seamlessly with researchers around the world to conduct large-scale clinical trials of vaccines to prevent diseases that disproportionately affect children in resource-limited settings. Findings from these studies drive local, national, and international policy and support evidence-based vaccination schedules.

Disease Areas: Epstein Barr virus (EBV), Bordetella pertussis (whooping cough), causes of neonatal sepsis, cytomegalovirus, influenza virus, pneumococcus, polio virus, respiratory syncytial virus (RSV), SARS-CoV-2

Major programs and initiatives:

  • Unraveling Maternal Milk Bolstering of Infant Gut Health
  • B’more Healthy
  • TyVAC: Typhoid Conjugate Vaccine Acceleration Consortium
  • Global Enteric Multicenter Study (GEMS)
  • Vaccine Impact on Diarrhea in Africa (VIDA)

Faculty pursuing research in this area:

  • Jason Bailey, PhD
  • James Campbell, MD
  • Wilbur Chen, MD
  • Sumanth Cherukumilli, MD
  • Amanda Driscoll, PhD
  • Meagan Fitzpatrick, PhD
  • Karen Kotloff, MD
  • Matthew Laurens, MD
  • Jose Lemme, PhD
  • Justin Ortiz, MD
  • Dilruba Nasrin, PhD
  • Marcela Pasetti, PhD
  • Milagritos Tapia, MD
  • Mark Travassos, MD
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