Hongxia Chen, BM, MS
- Academic Title: Research Associate
- Primary Appointment: Surgery
- Email: hongxia.chen@som.umaryland.edu
- Location: 20 Penn Street, Baltimore, 21201
- Phone (Primary): (410)706-1050
Education and Training
Education, Training and Work
B.M. Clinical Medicine, Baotou Medical College, Inner Mongolia, P.R. China
M.S. Internal Medicine, Tianjin Medical University, P.R. China
Resident Physician Rotation Training, Beijing Chaoyang Hospital, P.R. China
Clinic fellow, Emergency Department and EICU, Beijing No.1 Hospital of Integrated Traditional Chinese and Western Medicine, P.R. China
Attending physician, Department of Endocrinology and Metabolism and VIP ward, Beijing No.1 Hospital of Integrated Traditional Chinese and Western Medicine, P.R. China
Post-Doctoral Fellow, School of Pharmacy, University of Maryland Baltimore
Post-Doctoral Fellow, School of Medicine, University of Maryland Baltimore
Research/Clinical Keywords
Gastrointestinal diseases, Metabolic disorders, Aging, Wound repair, Autoimmunity, Inflammation, Stem cells, Mitochondrial function, noncoding RNA.
Highlighted Publications
1. B Warner, H Zhao*, H Chen*, A VanderStoep, J-Y Wang, L Xiao. Age-associated impairment of Paneth cells driven by microRNA-152 promotes intestinal epithelial vulnerability to pathological stress. Aging cell, May 2026. (*co-first author) [PMID: 42126142]
2. T Yu, Hee Chung, A VanderStoep, B Warner, H Chen, R Kozar, L Xiao, J-Y Wang. Long noncoding RNA GAS5 disrupts intestinal epithelial barrier function by increasing small vault RNA levels. JCI Insight, 2026. [PMID: 41569698]
3. C Cairns, T Chen, N Han, H Chen, Hee Chung, L Xiao, J-Y Wang. Polyamines regulate mitochondrial metabolism essential for intestinal epithelial renewal and wound healing. AJP Gastrointestinal and Liver Physiology, 2025. [PMID: 40471931]
4. W Wang, C Cao, V Pandian, H Ye, H Chen, L Zhang. Mac-1 regulates disease stage specific immunosuppression via the nitric oxide pathway in autoimmune disease. Sci Adv.2025. [PMID: 40344054]
5. S Wang, R Peng, H Chen, D Han, J Wu, Y Xu, Z Ying. Timing Determines Programming of Energy Homeostasis by Maternal PM2.5 Exposure in Mouse Models. Environ Pollution. 2024. [PMID: 39454811]
6. S Li, H Chen*, L Pi, Y Zhang, Y Ali, Q Cao. Quantification Of Collagenogenesis In Experimental Early-stage Alcoholic Liver Fibrosis Using Cis-4-[18F]fluoro-L-Proline microPET. Current Med Imaging, 2023. (*co-first author) [PMID: 37622557]
7. N Duan, H Chen*, Y Ali, L Pi, Q Cao. Cis-4-[18F] fluoro-L-proline PET/CT molecular imaging quantifying liver collagen genesis: No existing fibrotic deposition in experimental advanced-stage alcoholic liver fibrosis. Front. Nucl. Med, 2022. (*co-first author) [PMID: 39354960]
8. Y Wan, H Chen, Z Li, J Liang, Q Cao. Alcohol and Advanced Glycation End Product Synergistically Stimulate TNF-ɑ and TGF-β1 Production by Cytochrome P450 2E1 Expressing Macrophages. American Journal of Biomedical Science & Research, 2021. DOI:10.34297/AJBSR.2021.15.002070
9. S Li, X Sun, H Chen, J Liang, M Chen, Q Cao. Deletion of Interleukin 1 Receptor Associated Kinase 1 Improves TLR4/STAT1/PPARγ-Cd36 Signaling-Mediated Alcoholic Fatty Liver. Adv Res Gastroenteric & Hepatol. 2021. DOI:10.19080/ARGH.2021. 18.555983
10. X Sun, S Duan, A Cao, B Villagomez, R Lin, H Chen, L Pi, B Ren, R Chen, M Chen, Z Ying, S Fang. RRY inhibits Amyloid-β 1-42 Peptide Aggregation and Neurotoxicity. Journal of Alzheimer's Disease. 2021.DOI:10.3233/ADR-210012
11. H Chen, L Ma, q Yuan, Y Huang. Therapeutic Effect of Sitagliptin Combined with Metformin on Elderly Type 2 Diabetes. Chinese Journal of Microcirculation, ISSN:1007-8568, 2019-2(1), p18-22
12. H Chen, T Shi, Q Yuan, J Yang. Effects of Pioglitazone Combined with Acarbose on the Serum RBP4, Leptin and Vastatin Levels of Patients with Type 2 Diabetes Mellitus. Progress in Modern Biomedicine, ISSN:1673-6273, 2018-21(2), p4152-4155
13. H Chen, Y Shuai, J Zhang, Q Yuan, X Xing. Curative Efficacy of Insulin Sensitizer in Treatment of Type 2 Diabetes Intensive Treatment after Long-term Remission and its Effects on Urine Microal- bumin. Hebei Medical Journal, ISSN:1006-6233, 2018-7(1), p1100-1104
14. P Liu, W Chen, J Zhang, Q Yuan, S He, H Chen, W Sun, F Ma. Effect of meal staple rich dietary fiber on glucose metabolism in type 2 diabetes mellitus. Chinese Journal for Clinicians, ISSN:2095-8552, 2016-44(6), p24-28