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John D. Sorkin, MD, PhD

Academic Title:

Professor

Primary Appointment:

Medicine

Secondary Appointment(s):

Epidemiology & Public Health

Additional Title:

Chief, Biostatistics and Informatics, VAMC Geriatrics Research, Education, and Clinical Center; and Claude D. Pepper Older Americans Independence Center; and University of Maryland Nutrition Obesity Research Center

Location:

VAMC Room 4B-192

Phone (Primary):

(410) 605-7119

Fax:

(410) 605-7913

Education and Training

1969 – 1975

B.S., 1975

Brooklyn College

 

Mathematics           

City University of New York

 

 

Brooklyn, New York

 

 

 

1979 – 1980

Computer Science Graduate

Columbia University

(left graduate school prior to completing program to go to medical school)

Student

 

Department of Computer Science/Electrical Engineering

New York, New York

 

 

 

1980 - 1984

M. D., 1984

Universidad Autonoma de Guadalajara

Guadalajara, Mexico

 

 

 

1992 - 1999

Ph. D. Epidemiology, 1999

(Graduate training undertaken while working full time for the National Institute on Aging.)

 

The Johns Hopkins School of Hygiene and Public Health  Baltimore, Maryland

Dissertation: The Relation of Fasting and Two-Hour Glucose Concentrations to Cardiovascular Disease Incidence and All-Cause Mortality: An Evaluation of the Criteria for Diagnosing Diabetes. Trudy Bush, Ph.D. thesis advisor

 

 

 

Post Graduate Education and Training

1984 - 1985

Fifth Pathway

(Year of clinical clerkships in lieu of year of social service required of Mexican Medical Schools graduates)   

Mt. Sinai School of Medicine

City Hospital Center at Elmhurst

Elmhurst, Queens, New York

 

1985 - 1986

Internship (Internal Medicine)

 

University of Pittsburgh

Montefiore Hospital

Pittsburgh, Pennsylvania

 

 

 

1986 - 1988

Residency (Internal Medicine)

 

University of Pittsburgh

Montefiore Hospital

Pittsburgh, Pennsylvania

 

Additional Postgraduate Education

Sept 1999

NHLBI certificate course: Genetics Approaches to Complex Heart, Lung and Blood Diseases

 

The Jackson Laboratory, Bar Harbor Maine

 

Fellowships:

1988 - 1992

Clinical Fellow and Senior Staff Fellow

Metabolism Section

Laboratory of Clinical Physiology

 

Gerontology Research Center

National Institute on Aging

National Institutes of Health

Baltimore, Maryland. Mentor Dr. Reubin Andres.

 

1990 – 1992

Endocrinology Fellow

 

Francis Scott Key Medical Center Baltimore, Maryland. Supervisor Dr. Marc Blackman.

 

1992 – 1995

Epidemiology Training Fellow

 

Epidemiology, Biometry, and Demography Program

National Institute on Aging

Bethesda, Maryland. Mentor Dr. Tamara Harris.

 

Biosketch

My professional life revolves around statistics, epidemiology, and teaching. I am a Prof. in the, Dept. of Medicine, and the Dept. of Epidemiology and Public Health, Univ. Maryland Baltimore, Affiliate Prof. in the Dept. of Epidemiology and Biostatistics, Univ. Maryland College Park, and Affiliate Prof. in the Dept. of Computer Science and Electrical Engineering, Univ. of Maryland, Baltimore County. My training in Medicine, Epidemiology, and Computer Science (and more than a decade working and teaching in the field of computer science in both academia and industry) allow me to bring a wide range of experience and knowledge to my role as the leader of the Biostatistics and Informatics Cores of four federally funded research centers. For the last eighteen-years, I have been PI of the (1) Biostatistics Core of the Univ. of Maryland’s Claude D. Pepper Older Americans Independence Center, and of the (2) Biostatistics Core of the Baltimore VA Medical Center’s Geriatrics Research, Education, and Clinical Center; and since their inception eleven years ago, I have been PI of the Biostatistics Core of the (3) VA Maryland Exercise and Robotics Center of Excellence and the (4) Bio-statistics Subcore of the Mid-Atlantic Nutrition Obesity Research Center. I am a member of the Editorial Board of, and statistical reviewer for, the American Journal of Clinical Nutrition, was co-editor of Diabetes Metabolism Research and Reviews, and have been a faculty member of the Univ. of Maryland’s K30 Program training junior faculty scholars for more than seven years. My research explores the role of exercise as a therapy for chronic disease (e.g. diabetes, hyperlipidemia, hypertension), and diseases that result in ambulatory disability including stroke and peripheral vascular disease. I have published more than 130 papers and book chapters. Over the years I have had the opportunity to study risk factors for, and interventions designed to, lower risk for diabetes, cardiovascular disease, obesity and mortality and the genetics of longevity and to study interventions designed to promote recovery from chronic disease. I have mentored numerous graduate students, PhDs and MDs and mentor T32 scholars in statistics, epidemiology, and research ethics. I teach sections of several graduate classes and am co-course master of and statistician for, Research Practicum. Practicum takes graduate students through all phases of a research project, pro-posing a research question, reviewing the literature, designing an analysis plan, and analyzing data. I am co-course master of Clinical Research at UM, a course designed to help investigators start research careers, and was Senior Faculty Member of the NIA’s Summer Institute (Butler-Williams Scholars Program). 

 

Research/Clinical Keywords

Diabetes, Obesity, Longevity, Longitudinal Change in risk factors, Biostatistics, Informatics

Highlighted Publications

Sorkin J, Bloomfield DA. Computers for critical care. Heart Lung. 1982 Jul-Aug;11(4):287-93. PMID: 6919523

Shimokata H, Muller DC, Fleg JL, Sorkin J, Ziemba AW, Andres R. Age as independent determinant of glucose tolerance. Diabetes. 1991 Jan;40(1):44-51. PMID: 2015973

Cherry-Peppers G, Sorkin J, Andres R, Baum BJ, Ship JA. Salivary gland function and glucose metabolic status. J Gerontol. 1992 Jul;47(4):M130-4. PMID: 1624696

Seidell JC, Muller DC, Sorkin JD, Andres R. Fasting respiratory exchange ratio and resting metabolic rate as predictors of weight gain: the Baltimore Longitudinal Study on Aging. Int J Obes Relat Metab Disord. 1992 Sep;16(9):667-74. PMID: 1328091

Sorkin JD, Andres R, Muller DC, Baldwin HL, Fleg JL. Cholesterol as a risk factor for coronary heart disease in elderly men. The Baltimore Longitudinal Study of Aging. Ann Epidemiol. 1992 Jan-Mar;2(1-2):59-67. PMID: 1342266

Andres R, Muller DC, Sorkin JD. Long-term effects of change in body weight on all-cause mortality. A review. Ann Intern Med. 1993 Oct 1;119(7 Pt 2):737-43. PMID: 8363208

Breslow RA, Sorkin JD. Comparison of one-day and three-day calorie counts in hospitalized patients: a pilot study. J Am Geriatr Soc. 1993 Sep;41(9):923-7. PMID: 8409178

Corti MC, Guralnik JM, Salive ME, Sorkin JD. Serum albumin level and physical disability as predictors of mortality in older persons. JAMA. 1994 Oct 5;272(13):1036-42. PMID: 8089886
Abstract and commentary printed in: Corti M, Guralnik J, Salive M, Sorkin J, Serum albumin level and physical disability as predictors of mortality in older persons. ACP JOURNAL CLUB, 1995. 122:50-50.

Seidell JC, Andres R, Sorkin JD, Muller DC. The sagittal waist diameter and mortality in men: the Baltimore Longitudinal Study on Aging. Int J Obes Relat Metab Disord. 1994 Jan;18(1):61-7. PMID: 8130817

Sorkin JD, Muller D, Andres R. Body mass index and mortality in Seventh-day Adventist men. A critique and re-analysis. Int J Obes Relat Metab Disord. 1994 Nov;18(11):752-4. PMID: 7866475

Treuth MS, Ryan AS, Pratley RE, Rubin MA, Miller JP, Nicklas BJ, Sorkin J, Harman SM, Goldberg AP, Hurley BF. Effects of strength training on total and regional body composition in older men. J Appl Physiol (1985). 1994 Aug;77(2):614-20. Erratum in: J Appl Physiol 1994 Dec;77(6):followi. PMID: 8002507

Katzel LI, Sorkin KD, Colman E, Goldberg AP, Busby-Whitehead MJ, Lakatta LE, Becker LC, Lakatta EG, Fleg JL. Risk factors for exercise-induced silent myocardial ischemia in healthy volunteers. Am J Cardiol. 1994 Nov 1;74(9):869-74. PMID: 7977116.

Colman E, Katzel LI, Sorkin J, Coon PJ, Engelhardt S, Rogus E, Goldberg AP. The role of obesity and cardiovascular fitness in the impaired glucose tolerance of aging. Exp Gerontol. 1995 Nov-Dec;30(6):571-80. PMID: 8867526

Katzel LI, Bleecker ER, Colman EG, Rogus EM, Sorkin JD, Goldberg AP. Effects of weight loss vs aerobic exercise training on risk factors for coronary disease in healthy, obese, middle-aged and older men. A randomized controlled trial. JAMA. 1995 Dec 27;274(24):1915-21. PMID: 8568984

Sorkin JD, Bolton PA, Greenblatt J, Sithisarankul P, Vlahov D, Graham NM. Age, gender, and other predictors of the wasting syndrome among HIV-1-infected injecting drug users. Epidemiology. 1995 Mar;6(2):172-7. PMID: 7742405

Walston J, Silver K, Bogardus C, Knowler WC, Celi FS, Austin S, Manning B, Strosberg AD, Stern MP, Raben N, et al. Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N Engl J Med. 1995 Aug 10;333(6):343-7. PMID: 7609750.

Breslow RA, Sorkin JD, Frey CM, Kessler LG. Americans' knowledge of cancer risk and survival. Prev Med. 1997 Mar-Apr;26(2):170-7. PMID: 9085385

Edelstein SL, Knowler WC, Bain RP, Andres R, Barrett-Connor EL, Dowse GK, Haffner SM, Pettitt DJ, Sorkin JD, Muller DC, Collins VR, Hamman RF. Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies. Diabetes. 1997 Apr;46(4):701-10. PMCID: PMC2517225

Korrapati MR, Sorkin JD, Andres R, Muller DC, Loi CM, Vesell ES, Vestal RE. Acetylator phenotype in relation to age and gender in the Baltimore Longitudinal Study of Aging. J Clin Pharmacol. 1997 Feb;37(2):83-91. PMID: 9055133

Silver K, Mitchell BD, Walston J, Sorkin JD, Stern MP, Roth J, Shuldiner AR. TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans. Hum Genet. 1997 Dec;101(3):306-11. PMID: 9439659

Katzel LI, Fleg JL, Busby-Whitehead MJ, Sorkin JD, Becker LC, Lakatta EG, Goldberg AP. Exercise-induced silent myocardial ischemia in master athletes. Am J Cardiol. 1998 Feb 1;81(3):261-5. PMID: 9468064.

Rosen MJ, Sorkin JD, Goldberg AP, Hagberg JM, Katzel LI. Predictors of age-associated decline in maximal aerobic capacity: a comparison of four statistical models. J Appl Physiol (1985). 1998 Jun;84(6):2163-70. PMID: 9609813

Siegman AW, Townsend ST, Blumenthal RS, Sorkin JD, Civelek AC. Dimensions of anger and CHD in men and women: self-ratings versus spouse ratings. J Behav Med. 1998 Aug;21(4):315-36. PMID: 9789163

Rosen MJ, Sorkin JD, Goldberg AP, Hagberg JM, Katzel LI. Predictors of age-associated decline in maximal aerobic capacity: a comparison of four statistical models. J Appl Physiol (1985). 1998 Jun;84(6):2163-70. PMID: 9609813.

Hagberg JM, Ferrell RE, Katzel LI, Dengel DR, Sorkin JD, Goldberg AP. Apolipoprotein E genotype and exercise training-induced increases in plasma high-density lipoprotein (HDL)- and HDL2-cholesterol levels in overweight men. Metabolism. 1999 Aug;48(8):943-5. PMID: 10459553

Katzel LI, Sorkin JD, Goldberg AP. Exercise-induced silent myocardial ischemia and future cardiac events in healthy, sedentary, middle-aged and older men. J Am Geriatr Soc. 1999 Aug;47(8):923-9. PMID: 10443851

Sorkin JD, Muller DC, Andres R. Longitudinal change in the heights of men and women: consequential effects on body mass index. Epidemiol Rev. 1999;21(2):247-60. PMID: 10682261

Sorkin JD, Muller DC, Andres R. Longitudinal change in height of men and women: implications for interpretation of the body mass index: the Baltimore Longitudinal Study of Aging. Am J Epidemiol. 1999 Nov 1;150(9):969-77. PMID: 10547143

Gardner AW, Katzel LI, Sorkin JD, Killewich LA, Ryan A, Flinn WR, Goldberg AP. Improved functional outcomes following exercise rehabilitation in patients with intermittent claudication. J Gerontol A Biol Sci Med Sci. 2000 Oct;55(10):M570-7. PMID: 11034229

Katzel LI, Sorkin J, Bradham D, Gardner AW. Comorbidities and the entry of patients with peripheral arterial disease into an exercise rehabilitation program. J Cardiopulm Rehabil. 2000 May-Jun;20(3):165-71. PMID: 10860198

Andres R, Muller DC, Sorkin JD. To discontinue glucose tolerance or not? Quantification of misdiagnoses from a comprehensive literature review. Diabetes Research and Clinical Practice, 2000 50:34-5.

Barzilai N, Gabriely I, Gabriely M, Iankowitz N, Sorkin JD. Offspring of centenarians have a favorable lipid profile. J Am Geriatr Soc. 2001 Jan;49(1):76-9. PMID: 11207846

Gardner AW, Katzel LI, Sorkin JD, Bradham DD, Hochberg MC, Flinn WR, Goldberg AP. Exercise rehabilitation improves functional outcomes and peripheral circulation in patients with intermittent claudication: a randomized controlled trial. J Am Geriatr Soc. 2001 Jun;49(6):755-62. PMID: 11454114

Katzel LI, Sorkin JD, Fleg JL. A comparison of longitudinal changes in aerobic fitness in older endurance athletes and sedentary men. J Am Geriatr Soc. 2001 Dec;49(12):1657-64. PMID: 11844000

Katzel LI, Sorkin JD, Powell CC, Gardner AW. Comorbidities and exercise capacity in older patients with intermittent claudication. Vasc Med. 2001;6(3):157-62. PMID: 11789970

Macko RF, Smith GV, Dobrovolny CL, Sorkin JD, Goldberg AP, Silver KH. Treadmill training improves fitness reserve in chronic stroke patients. Arch Phys Med Rehabil. 2001 Jul;82(7):879-84. PMID: 11441372

Mitchell BD, Hsueh WC, King TM, Pollin TI, Sorkin J, Agarwala R, Schäffer AA, Shuldiner AR. Heritability of life span in the Old Order Amish. Am J Med Genet. 2001 Sep 1;102(4):346-52. PMID: 11503162

Münzer T, Harman SM, Hees P, Shapiro E, Christmas C, Bellantoni MF, Stevens TE, O'Connor KG, Pabst KM, St Clair C, Sorkin JD, Blackman MR. Effects of GH and/or sex steroid administration on abdominal subcutaneous and visceral fat in healthy aged women and men. J Clin Endocrinol Metab. 2001 Aug;86(8):3604-10. PMID: 11502785

Blackman MR, Sorkin JD, Münzer T, Bellantoni MF, Busby-Whitehead J, Stevens TE, Jayme J, O'Connor KG, Christmas C, Tobin JD, Stewart KJ, Cottrell E, St Clair C, Pabst KM, Harman SM. Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial. JAMA. 2002 Nov 13;288(18):2282-92. PMID: 12425705

Christmas C, O'Connor KG, Harman SM, Tobin JD, Münzer T, Bellantoni MF, Clair CS, Pabst KM, Sorkin JD, Blackman MR. Growth hormone and sex steroid effects on bone metabolism and bone mineral density in healthy aged women and men. J Gerontol A Biol Sci Med Sci. 2002 Jan;57(1):M12-8. PMID: 11773207

Gardner AW, Katzel LI, Sorkin JD, Goldberg AP. Effects of long-term exercise rehabilitation on claudication distances in patients with peripheral arterial disease: a randomized controlled trial. J Cardiopulm Rehabil. 2002 May-Jun;22(3):192-8. PMID: 12042688

Hafer-Macko CE, Ivey FM, Gyure KA, Sorkin JD, Macko RF. Reduced thrombomodulin in human peripheral nerve microvasculature. Muscle Nerve. 2002 Aug;26(2):218-24. PMID: 12210386

Hafer-Macko CE, Ivey FM, Gyure KA, Sorkin JD, Macko RF. Thrombomodulin deficiency in human diabetic nerve microvasculature. Diabetes. 2002 Jun;51(6):1957-63. PMID: 12031986

Izquierdo-Porrera AM, Manchanda R, Powell CC, Sorkin JD, Bradham DD. Factors influencing the use of computer technology in the collection of clinical data in a predominantly African-American population. J Am Geriatr Soc. 2002 Aug;50(8):1411-5. PMID: 12164999

Joseph LJ, Ryan AS, Sorkin J, Mangano C, Brendle DC, Corretti MC, Gardner AW, Katzel LI. Body fat distribution and flow-mediated endothelium-dependent vasodilation in older men. Int J Obes Relat Metab Disord. 2002 May;26(5):663-9. PMID: 12032751

Lynch NA, Ryan AS, Berman DM, Sorkin JD, Nicklas BJ. Comparison of VO2max and disease risk factors between perimenopausal and postmenopausal women. Menopause. 2002 Nov-Dec;9(6):456-62. PMID: 12439106

Punjabi NM, Sorkin JD, Katzel LI, Goldberg AP, Schwartz AR, Smith PL. Sleep-disordered breathing and insulin resistance in middle-aged and overweight men. Am J Respir Crit Care Med. 2002 Mar 1;165(5):677-82. PMID: 11874813

Brendle DC, Joseph LJ, Sorkin JD, McNelly D, Katzel LI. Aging and marathon times in an 81-year-old man who competed in 591 marathons. Am J Cardiol. 2003 May 1;91(9):1154-6. PMID: 12714171

Dobrovolny CL, Ivey FM, Rogers MA, Sorkin JD, Macko RF. Reliability of treadmill exercise testing in older patients with chronic hemiparetic stroke. Arch Phys Med Rehabil. 2003 Sep;84(9):1308-12. PMID: 13680566

Nicklas BJ, Dennis KE, Berman DM, Sorkin J, Ryan AS, Goldberg AP. Lifestyle intervention of hypocaloric dieting and walking reduces abdominal obesity and improves coronary heart disease risk factors in obese, postmenopausal, African-American and Caucasian women. J Gerontol A Biol Sci Med Sci. 2003 Feb;58(2):181-9. PMID: 12586858

Treuth MS, Butte NF, Sorkin JD. Predictors of body fat gain in nonobese girls with a familial predisposition to obesity. Am J Clin Nutr. 2003 Dec;78(6):1212-8. PMID: 14668285

Luft AR, McCombe-Waller S, Whitall J, Forrester LW, Macko R, Sorkin JD, Schulz JB, Goldberg AP, Hanley DF. Repetitive bilateral arm training and motor cortex activation in chronic stroke: a randomized controlled trial. JAMA. 2004 Oct 20;292(15):1853-61. Erratum in: JAMA. 2004 Nov 24;292(20):2470. PMCID: PMC2930817

Neumann SA, Waldstein SR, Sellers JJ 3rd, Thayer JF, Sorkin JD. Hostility and distraction have differential influences on cardiovascular recovery from anger recall in women. Health Psychol. 2004 Nov;23(6):631-40. PMID: 15546231

Ryan AS, Ivey FM, Hurlbut DE, Martel GF, Lemmer JT, Sorkin JD, Metter EJ, Fleg JL, Hurley BF. Regional bone mineral density after resistive training in young and older men and women. Scand J Med Sci Sports. 2004 Feb;14(1):16-23. PMID: 14723783

Izquierdo-Porrera AM, Gardner AW, Bradham DD, Montgomery PS, Sorkin JD, Powell CC, Katzel LI. Relationship between objective measures of peripheral arterial disease severity to self-reported quality of life in older adults with intermittent claudication. J Vasc Surg. 2005 Apr;41(4):625-30. PMID: 15874926

Macko RF, Ivey FM, Forrester LW, Hanley D, Sorkin JD, Katzel LI, Silver KH, Goldberg AP. Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial. Stroke. 2005 Oct;36(10):2206-11. PMID: 16151035

Shaughnessy M, Michael KM, Sorkin JD, Macko RF. Steps after stroke: capturing ambulatory recovery. Stroke. 2005 Jun;36(6):1305-7. PMID: 15879321

Sorkin J, Post W, Pollin TI, O'Connell JR, Mitchell BD, Shuldiner AR. Exploring the genetics of longevity in the Old Order Amish. Mech Ageing Dev. 2005 Feb;126(2):347-50. PMID: 15621217

Sorkin JD, Muller DC, Fleg JL, Andres R. The relation of fasting and 2-h postchallenge plasma glucose concentrations to mortality: data from the Baltimore Longitudinal Study of Aging with a critical review of the literature. Diabetes Care. 2005 Nov;28(11):2626-32. PMID: 16249530

Muniyappa R, Wong KA, Baldwin HL, Sorkin JD, Johnson ML, Bhasin S, Harman SM, Blackman MR. Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men. J Clin Endocrinol Metab. 2006 Nov;91(11):4445-52. PMID: 16926252.

Ivey FM, Ryan AS, Hafer-Macko CE, Garrity BM, Sorkin JD, Goldberg AP, Macko RF. High prevalence of abnormal glucose metabolism and poor sensitivity of fasting plasma glucose in the chronic phase of stroke. Cerebrovasc Dis. 2006;22(5-6):368-71. Epub 2006 Aug 3. PMID: 16888377

McArdle PF, Pollin TI, O'Connell JR, Sorkin JD, Agarwala R, Schäffer AA, Streeten EA, King TM, Shuldiner AR, Mitchell BD. Does having children extend life span? A genealogical study of parity and longevity in the Amish. J Gerontol A Biol Sci Med Sci. 2006 Feb;61(2):190-5. PMID: 16510865

Münzer T, Rosen CJ, Harman SM, Pabst KM, St Clair C, Sorkin JD, Blackman MR. Effects of GH and/or sex steroids on circulating IGF-I and IGFBPs in healthy, aged women and men. Am J Physiol Endocrinol Metab. 2006 May;290(5):E1006-13. PMID: 16390864

Oursler KK, Sorkin JD, Smith BA, Katzel LI. Reduced aerobic capacity and physical functioning in older HIV-infected men. AIDS Res Hum Retroviruses. 2006 Nov;22(11):1113-21. PMID: 17147498

Song Q, Cole JW, O'Connell JR, Stine OC, Gallagher M, Giles WH, Mitchell BD, Wozniak MA, Stern BJ, Sorkin JD, McArdle PF, Naj AC, Xu Q, Gibbons GH, Kittner SJ. Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study. Hum Mol Genet. 2006 Aug 15;15(16):2468-78. Epub 2006 Jul 11. PMCID: PMC1634802.

Cole JW, Naj AC, O'Connell JR, Stine OC, Sorkin JD, Wozniak MA, Stern BJ, Yepes M, Lawrence DA, Reinhart LJ, Strickland DK, Mitchell BD, Kittner SJ. Neuroserpin polymorphisms and stroke risk in a biracial population: the stroke prevention in young women study. BMC Neurol. 2007 Oct 25;7:37. PMCID: PMC2169251

Dolan MS, Sorkin JD, Hoffman DJ. Birth weight is inversely associated with central adipose tissue in healthy children and adolescents. Obesity (Silver Spring). 2007 Jun;15(6):1600-8. PMID: 17557998

Hafer-Macko CE, Ivey FM, Sorkin JD, Macko RF. Microvascular tissue plasminogen activator is reduced in diabetic neuropathy. Neurology. 2007 Jul 17;69(3):268-74. PMID: 17636064

Muniyappa R, Sorkin JD, Veldhuis JD, Harman SM, Münzer T, Bhasin S, Blackman MR. Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E769-75. PMID: 17550998

Patterson SL, Forrester LW, Rodgers MM, Ryan AS, Ivey FM, Sorkin JD, Macko RF. Determinants of walking function after stroke: differences by deficit severity. Arch Phys Med Rehabil. 2007 Jan;88(1):115-9. PMID: 17207686

Bhat VM, Cole JW, Sorkin JD, Wozniak MA, Malarcher AM, Giles WH, Stern BJ, Kittner SJ. Dose-response relationship between cigarette smoking and risk of ischemic stroke in young women. Stroke. 2008 Sep;39(9):2439-43. PMCID: PMC3564048

Cole JW, Brown DW, Giles WH, Stine OC, O'Connell JR, Mitchell BD, Sorkin JD, Wozniak MA, Stern BJ, Sparks MJ, Dobbins MT, Shoffner LT, Zappala NK, Reinhart LJ, Kittner SJ. Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study. Thromb J. 2008 Aug 26;6:11. PMCID: PMC2533289.

Ferrara CM, Goldberg AP, Nicklas BJ, Sorkin JD, Ryan AS. Sex differences in insulin action and body fat distribution in overweight and obese middle-aged and older men and women. Appl Physiol Nutr Metab. 2008 Aug;33(4):784-90. PMCID: PMC2920284

Luft, A Luft AR, Macko RF, Forrester LW, Villagra F, Ivey F, Sorkin JD, Whitall J, McCombe-Waller S, Katzel L, Goldberg AP, Hanley DF. Treadmill exercise activates subcortical neural networks and improves walking after stroke: a randomized controlled trial. Stroke. 2008 Dec;39(12):3341-50. PMCID: PMC2929142

Mitchell BD, McArdle PF, Shen H, Rampersaud E, Pollin TI, Bielak LF, Jaquish C, Douglas JA, Roy-Gagnon MH, Sack P, Naglieri R, Hines S, Horenstein RB, Chang YP, Post W, Ryan KA, Brereton NH, Pakyz RE, Sorkin J, Damcott CM, O'Connell JR, Mangano C, Corretti M, Vogel R, Herzog W, Weir MR, Peyser PA, Shuldiner AR. The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. Am Heart J. 2008 May;155(5):823-8. PMCID: PMC2443415

Resnick B, Michael K, Shaughnessy M, Nahm ES, Kobunek S, Sorkin J, Orwig D, Goldberg A, Macko RF. Inflated perceptions of physical activity after stroke: pairing self-report with physiologic measures. J Phys Act Health. 2008 Mar;5(2):308-18. PMID: 18382039

Roy-Gagnon MH, Weir MR, Sorkin JD, Ryan KA, Sack PA, Hines S, Bielak LF, Peyser PA, Post W, Mitchell BD, Shuldiner AR, Douglas JA. Genetic influences on blood pressure response to the cold pressor test: results from the Heredity and Phenotype Intervention Heart Study. J Hypertens. 2008 Apr;26(4):729-36. PMCID: PMC3337701.

Skidmore FM, Patterson SL, Shulman LM, Sorkin JD, Macko RF. Pilot safety and feasibility study of treadmill aerobic exercise in Parkinson disease with gait impairment. J Rehabil Res Dev. 2008;45(1):117-24. PMID: 18566930.

Mez JB, Cole JW, Howard TD, Macclellan LR, Stine OC, O'Connell JR, Wozniak MA, Stern BJ, Sorkin JD, Mitchell BD, Kittner SJ. Evaluation of self-reported ethnicity in a case-control population: the stroke prevention in young women study. BMC Res Notes. 2009 Dec 18;2:260. PMCID: PMC2801514

Miller M, Beach V, Sorkin JD, Mangano C, Dobmeier C, Novacic D, Rhyne J, Vogel RA. Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance. J Am Diet Assoc. 2009 Apr;109(4):713-7. PMCID: PMC2693202

Münzer T, Harman SM, Sorkin JD, Blackman MR. Growth hormone and sex steroid effects on serum glucose, insulin, and lipid concentrations in healthy older women and men. J Clin Endocrinol Metab. 2009 Oct;94(10):3833-41. PMCID: PMC2758730

Oursler KK, Katzel LI, Smith BA, Scott WB, Russ DW, Sorkin JD. Prediction of cardiorespiratory fitness in older men infected with the human immunodeficiency virus: clinical factors and value of the six-minute walk distance. J Am Geriatr Soc. 2009 Nov;57(11):2055-61. PMCID: PMC3049945

Stuart M, Benvenuti F, Macko R, Taviani A, Segenni L, Mayer F, Sorkin JD, Stanhope SJ, Macellari V, Weinrich M. Community-based adaptive physical activity program for chronic stroke: feasibility, safety, and efficacy of the Empoli model. Neurorehabil Neural Repair. 2009 Sep;23(7):726-34. PMCID: PMC3024240

Weir MR, Yeh F, Silverman A, Devereux RB, Galloway JM, Henderson JA, Howard WJ, Russell M, Wilson C, Ratner R, Sorkin J, Umans JG, Fleg JL, Stylianou M, Lee E, Howard BV. Safety and feasibility of achieving lower systolic blood pressure goals in persons with type 2 diabetes: the SANDS trial. J Clin Hypertens (Greenwich). 2009 Oct;11(10):540-8. PMCID: PMC4182961

Daley E, Streeten EA, Sorkin JD, Kuznetsova N, Shapses SA, Carleton SM, Shuldiner AR, Marini JC, Phillips CL, Goldstein SA, Leikin S, McBride DJ Jr. Variable bone fragility associated with an Amish COL1A2 variant and a knock-in mouse model. J Bone Miner Res. 2010 Feb;25(2):247-61. PMCID: PMC3153383

Klein-Schwartz W, Sorkin JD, Doyon S. Impact of the voluntary withdrawal of over-the-counter cough and cold medications on pediatric ingestions reported to poison centers. Pharmacoepidemiol Drug Saf. 2010 Aug;19(8):819-24. PMID: 20533537.

Muniyappa R, Veldhuis JD, Harman SM, Sorkin JD, Blackman MR. Effects of testosterone administration on nocturnal cortisol secretion in healthy older men. J Gerontol A Biol Sci Med Sci. 2010 Nov;65(11):1185-92. PMCID: PMC2954240

Onwudiwe NC, Stuart B, Zuckerman IH, Sorkin JD. Obesity and Medicare expenditure: accounting for age-related height loss. Obesity (Silver Spring). 2011 Jan;19(1):204-11. PMCID: PMC3061207

Whitall J, Waller SM, Sorkin JD, Forrester LW, Macko RF, Hanley DF, Goldberg AP, Luft A. Bilateral and unilateral arm training improve motor function through differing neuroplastic mechanisms: a single-blinded randomized controlled trial. Neurorehabil Neural Repair. 2011 Feb;25(2):118-29. PMCID: PMC3548606

Crawford GB, Khedkar A, Flaws JA, Sorkin JD, Gallicchio L. Depressive symptoms and self-reported fast-food intake in midlife women. Prev Med. 2011 Mar-Apr;52(3-4):254-7. PMCID: PMC3062726.

Oursler KK, Goulet JL, Crystal S, Justice AC, Crothers K, Butt AA, Rodriguez-Barradas MC, Favors K, Leaf D, Katzel LI, Sorkin JD. Association of age and comorbidity with physical function in HIV-infected and uninfected patients: results from the Veterans Aging Cohort Study. AIDS Patient Care STDS. 2011 Jan;25(1):13-20. PMCID: PMC3030913

Katzel LI, Sorkin JD, Macko RF, Smith B, Ivey FM, Shulman LM. Repeatability of aerobic capacity measurements in Parkinson disease. Med Sci Sports Exerc. 2011 Dec;43(12):2381-7. PMCID: PMC3701959

Hyun, Hyun SW, Anglin IE, Liu A, Yang S, Sorkin JD, Lillehoj E, Tonks NK, Passaniti A, Goldblum SE. Diverse injurious stimuli reduce protein tyrosine phosphatase-μ expression and enhance epidermal growth factor receptor signaling in human airway epithelia. Exp Lung Res. 2011 Aug;37(6):327-43. PMCID: PMC3560916

Resnick B, Michael K, Shaughnessy M, Nahm ES, Sorkin JD, Macko R. Exercise intervention research in stroke: optimizing outcomes through treatment fidelity. Top Stroke Rehabil. 2011 Oct;18 Suppl 1:611-9. PMCID: PMC3738053

Zhu Y, Sorkin JD, Dwyer D, Groves C, Steinberger EK. Predictors of repeated PSA testing among black and white men from the Maryland Cancer Survey, 2006. Prev Chronic Dis. 2011 Sep;8(5):A114. Epub 2011 Aug 15. PMCID: PMC3181187
Reprinted as: Zhu Y, Sorkin JD, Dwyer D, Groves C, Steinberger EK. INVESTIGACIÓN ORIGINAL Predictores de pruebas PSA repetidas en hombres negros y blancos obtenidos de la Encuesta sobre el Cáncer en Maryland, 2006. INVESTIGACIÓN, 2011. 8(5):10_0219_es.

Aslinia FM, Bagi P, Sorkin JD, Williams RB, Knodell RG, Sorkin LF, Greenwald BD, Steele A, Raufman JP. Anatomic classification of the endoscopic appearance of the normal appendiceal orifice: a novel tool for recognition and documentation of cecal intubation. Clin Anat. 2012 May;25(4):496-502. PMCID: PMC4041536.

Ryan AS, Ortmeyer HK, Sorkin JD. Exercise with calorie restriction improves insulin sensitivity and glycogen synthase activity in obese postmenopausal women with impaired glucose tolerance. Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E145-52. PMCID: PMC3328088

Katzel LI, Ivey FM, Sorkin JD, Macko RF, Smith B, Shulman LM. Impaired economy of gait and decreased six-minute walk distance in Parkinson's disease. Parkinsons Dis. 2012;2012:241754. PMCID: PMC3171762.

Nakano K, Pinnow E, Flaws JA, Sorkin JD, Gallicchio L. Reproductive history and hot flashes in perimenopausal women. J Womens Health (Larchmt). 2012 Apr;21(4):433-9. PMCID: PMC3321671

Ivey FM, Katzel LI, Sorkin JD, Macko RF, Shulman LM. The unified Parkinson's disease rating scale as a predictor of peak aerobic capacity and ambulatory function. J Rehabil Res Dev. 2012;49(8):1269-76. PMID: 23341319

Shulman LM, Katzel LI, Ivey FM, Sorkin JD, Favors K, Anderson KE, et al. Randomized clinical trial of 3 types of physical exercise for patients with Parkinson disease. JAMA Neurol. 2013 Feb;70(2):183-90. PMID: 23128427

Dowling TC, Wang ES, Ferrucci L, Sorkin JD. Glomerular filtration rate equations overestimate creatinine clearance in older individuals enrolled in the Baltimore longitudinal study on aging: Impact on renal drug dosing. Pharmacotherapy. 2013 Sep;33(9):912-21. PMCID: PMC3732548

Stafford KA, Sorkin JD, Steinberger EK. Influenza vaccination among cancer survivors: Disparities in prevalence between blacks and whites. J Cancer Surviv. 2013 Jun;7(2):183-90. PMID: 23315210

Viswanath A, Kerns TJ, Sorkin JD, Dwyer DM, Groves C, Steinberger EK. Self-reported oral cancer screening by smoking status in Maryland: Trends over time. J Public Health Dent. 2013 Fall;73(4):261-70. PMCID: PMC4267533

Oursler, K, Tate, J, Gill, TM, Crothers, K, Brown, T, Crystal Ph, DS, Womack J., Leaf DA, Sorkin JD, Justice A. Association of the veterans aging cohort study index with exercise capacity in HIV-infected adults. AIDS Res Hum Retroviruses. 2013 Sep;29(9):1218-23. PMCID: PMC3749694.

Capuano MM, Sorkin JD, Chang YP, Ling H, O Connell JR, Rothman PB, Mitchell BD, Silver KD (2013) Polymorphisms in the SOCS7 gene and glucose homeostasis traits. BMC Res Notes 6:235. doi: 10.1186/1756-0500-6-235. PMCID: PMC3686602

Stookey AD, McCusker MG, Sorkin JD, Katzel LI, Shaughnessy M, Macko RF, Ivey FM. Test-retest reliability of portable metabolic monitoring after disabling stroke. Neurorehabil Neural Repair. 2013 Nov-Dec;27(9):872-7. PMCID: PMC4060519.

McAninch J, Greene C, Sorkin JD, Lavoie MC, Smith GS. Higher psychological distress is associated with unintentional injuries in US adults. Inj Prev. 2014 Aug;20(4):258-65. doi: 10.1136/injuryprev-2013-040958. Epub 2013 Oct 30. PMCID: PMC4006313.

Barton JE, Sorkin JD. Design and evaluation of prosthetic shoulder controller. J Rehabil Res Dev 2014;51:711-26. PMID: 25357185

Onwudiwe NC, Kwok Y, Onukwugha E, Sorkin JD, Zuckerman IH, Shaya FT, Daniel Mullins C. Cardiovascular event-free survival after adjuvant radiation therapy in breast cancer patients stratified by cardiovascular risk. Cancer Med 2014;3:1342-52. PMCID: PMC4302684

Croft L, Sorkin J, Gallicchio L. Marital status and optimism score among breast cancer survivors. Support Care Cancer 2014;22:3027-34. PMID: 24908428

Sorkin JD, Vasaitis TS, Streeten E, Ryan AS, Goldberg AP. Evidence for threshold effects of 25-hydroxyvitamin D on glucose tolerance and insulin resistance in black and white obese postmenopausal women. J Nutr 2014;144:734-42. PMCID: PMC3985830

Hess AS, Kleinberg M, Sorkin JD, Netzer G, Johnson JK, Shardell M, Thom KA, Harris AD, Roghmann MC. Prior colonization is associated with increased risk of antibiotic-resistant Gram-negative bacteremia in cancer patients. Diagn Microbiol Infect Dis. 2014 May;79(1):73-6. PMCID: PMC4440656.

Sorkin JD. BMI, age, and mortality: the slaying of a beautiful hypothesis by an ugly fact. Am J Clin Nutr 2014;99:759-60. PMCID: PMC3953878

McAninch J, Greene C, Sorkin JD, Lavoie MC, Smith GS. Higher psychological distress is associated with unintentional injuries in US adults. Inj Prev 2014;20:258-65. PMCID: PMC4006313

Pepin CS, Thom KA, Sorkin JD, et al. Risk factors for central-line-associated bloodstream infections: a focus on comorbid conditions. Infect Control Hosp Epidemiol 2015;36:479-81. PMCID: PMC4367124

Klyushnenkova EN, Sorkin JD, Gallicchio L. Association of obesity and sleep problems among breast cancer survivors: results from a registry-based survey study. Support Care Cancer 2015. PMID: 25773672

Verceles AC, Weiler B, Koldobskiy D, Goldberg AP, Netzer G, Sorkin JD. Association between Vitamin D status and weaning from prolonged mechanical ventilation in survivors of critical illness. Respir Care 2015. PMID: 25715347

Serra MC, Ryan AS, Sorkin JD, Favor KH, Goldberg AP. High adipose LPL activity and adipocyte hypertrophy reduce visceral fat and metabolic risk in obese, older women. Obesity (Silver Spring) 2015;23:602-7. PMCID: PMC4340730

Seliger SL, de Lemos J, Neeland IJ, Christenson R, Gottdiener J, Drazner MH, Berry J, Sorkin J, deFilippi C. Older Adults, "Malignant" Left Ventricular Hypertrophy, and Associated Cardiac-Specific Biomarker Phenotypes to Identify the Differential Risk of New-Onset Reduced Versus Preserved Ejection Fraction Heart Failure: CHS (Cardiovascular Health Study). JACC Heart Fail. 2015 Jun;3(6):445-55. PMCID: PMC4458213

Roghmann, M.C., Johnson, J.K., Sorkin, J.D., Langenberg, P., Lydecker, A., Sorace, B., Levy, L. Mody, L., Transmission of Methicillin-Resistant Staphylococcus aureus (MRSA) to Healthcare Worker Gowns and Gloves During Care of Nursing Home Residents. Infect Control Hosp Epidemiol, 2015: p. 1-81:

Masnick M., Morgan D.J., Sorkin J.D., Kim E., Brown J.P., Rheingans P., Harris A.D., Lack of Patient Understanding of Hospital-Acquired Infection Data Published on the Centers for Medicare and Medicaid Services Hospital Compare Website. Infect Control Hosp Epidemiol, 2016. 37(2): p. 182-7 PMID:26592554.

Barton J.E., Roy A., Sorkin J.D., Rogers M.W., Macko R., An Engineering Model of Human Balance Control-Part I: Biomechanical Model. J Biomech Eng, 2016. 138(1) PubMed PMID: 26328608.

Burcu M., Steinberger E.K., Sorkin J.D., Health care access and smoking cessation among cancer survivors: implications for the Affordable Care Act and survivorship care. J Cancer Surviv, 2016. 10(1): p. 1-10. .PMID: 25862543

Barton J.E., Graci V., Hafer-Macko C., Sorkin J.D., Macko R., Dynamic Balanced Reach: A Temporal and Spectral Analysis across Increasing Performance Demands. J Biomech Eng, 2016.

Masnick M., Morgan D.J., Macek M.D., Sorkin J.D., Brown J.P., Rheingans P., Harris A.D., Improving the Understanding of Publicly Reported Healthcare-Associated Infection (HAI) Data. Infect Control Hosp Epidemiol, 2016: p. 1-6.

Miller M., Sorkin J.D., Mastella L., Sutherland A., Rhyne J., Donnelly P., Simpson K., Goldberg A.P., Poly is more effective than monounsaturated fat for dietary management in the metabolic syndrome: The muffin study. J Clin Lipidol, 2016. 10(4): p. 996-1003, PMCID PMC5010036

Woytowicz E.J., Rietschel J.C., Goodman R.N., Conroy S.S., Sorkin J.D., Whitall J., McCombe Waller S., Determining Levels of Upper Extremity Movement Impairment by Applying Cluster Analysis to Upper Extremity Fugl-Meyer Assessment in Chronic Stroke. Arch Phys Med Rehabil, 2016.

Koola M.M., Sorkin J.D., Fargotstein M., Brown W.V., Cuthbert B., Hollis J., Raines J.K., Duncan E.J., Predictors of Calf Arterial Compliance in Male Veterans With Psychiatric Diagnoses. Prim Care Companion CNS Disord, 2016. 18(3).

Oursler K.A., Sorkin J.D., HIV and Aging. Int J Infect Dis, 2016. 53: p. 59-60.