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Jacob B. Blumenthal, MD

Academic Title:

Assistant Professor

Primary Appointment:

Medicine

Additional Title:

Co-Director: GRECC Assessment Clinic, VA Career Development Awardee in Aging

Location:

Baltimore VA Medical Center, Room 4B-194

Phone (Primary):

(410) 605-5428

Fax:

(410) 605-7913

Education and Training

1989: A.B. with Honors, Philosophy, Brown University; Providence, RI         

1994: Doctor of Medicine, Brown University; Providence, RI       

1994-1995: Internship, Internal Medicine, University of Michigan Medical Center; Ann Arbor, MI

1995-1997: Residency, General Internal Medicine, Rhode Island Hospital/Brown University; Providence, RI

1997-2000: Fellowship, Geriatric Medicine, Johns Hopkins University; Baltimore, MD

Biosketch

I am a clinically trained geriatrician and clinical investigator focused on improving the function and quality of older adults with chronic conditions.  Specifically, we study the biological underpinnings of many age-associated conditions (including metabolic dysfunction, changes in body composition, atherosclerosis and cognitive decline) as well as their potential modifiability through lifestyle interventions.  We are also interested in novel models of care delivery to increase access as well as improve function and quality of life while reducing complications/costs.  I have extensive experience assessing veterans, and through my clinical work developed a deep appreciation for the importance of so-called “safety” issues, with a particular interest in the burdens of medications on older individuals with multiple comorbidities.

I am also deeply involved in education, teaching at all levels of the medical school as well as trainees across a number of professions.  I have mentored a number of students over the past decade, and increased the prominence of Geriatrics on campus.  I have been Co-Director of the University of Maryland Geriatric Medicine Fellowship since 2008, and since 2014 have been both Director of the Baltimore VAMC’s Special Fellowship in Advanced Geriatrics and Acting Associate Director for Education and Evaluation of the Baltimore Geriatric Research, Education and Clinical Center (GRECC).

Research/Clinical Keywords

Geriatrics, Function, Metabolism, Safety

Highlighted Publications

Blumenthal JB, R Andersen, B Mitchell, M Seibert, H Yang, H Herzog, B Beamer, S Franckowiak, J Walston. Novel Neuropeptide Y1 and Y5 Receptor Gene Variants’ Associations with Serum Triglyceride and HDL Cholesterol Levels. Clinical Genetics 2002; 62(3): 196-202.

Blumenthal JB, MN Blumenthal. Genetics of Asthma. MedicalClinicsofNorthAmerica 2002;86(5): 937-950. PubMed PMID: 12428539.

Jacob Blumenthal, Ellen Plummer and Steven R. Gambert. Trauma in the Elderly: Causes and Prevention. Clinical Geriatrics, 2010; 18(1): 21-4.

Susan K. Fried, Thomas Tittelbach, Jacob Blumenthal, Urmila Sreenivasan, Linda Robey, Jamie Yi, Sumbul Khan, Courtney Hollender, Alice S. Ryan and Andrew P. Goldberg. Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian post-menopausal women. Journal of Lipid Research, 2010; 51(5): 1193-200.

Joseph LJ, Prigeon RL, Blumenthal JB, Ryan AS, Goldberg AP. Weight Loss and Low-Intensity Exercise for the Treatment of Metabolic Syndrome in Obese Postmenopausal Women. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2011; doi: 10.1093/Gerona/glr093.

Additional Publication Citations

Serra MC, JB Blumenthal, AS Ryan. Impact of Weight Loss and Aerobic Exercise on Nutrition and Bone Mineral Density in African American and Caucasian Postmenopausal Women. Journal of Aging Research and Clinical Practice 2013: 2(1) 11-16.

Ryan AS, Li G, Blumenthal JB, Ortmeyer HK. Aerobic Exercise + Weight Loss Decreases Skeletal Muscle Myostatin Expression and Improves Insulin Sensitivity in Older Adults. Obesity; 2013: 21 (7) 1350-6.

Yang R, Blumenthal JB, Glynn N, Lee, MJ, Goldberg A, Gong DW, Ryan AS. Decrease in Circulating SAA levels is Correlated with Reduction of Abdominal SAA Secretion During Weight Loss. Obesity; 2014; 22 (4): 1085-90.

Prior SJ, Blumenthal JB, Katzel LI, Goldberg AP, Ryan AS. Increased skeletal muscle capillarization after aerobic exercise training and weight loss predicts improved insulin sensitivity and glucose tolerance in older adults with IGT. Diabetes Care, 2014; 37(5): 1469-75. doi: 10.2337/dc13-2358. Epub 2014 Mar 4. PubMed PMID: 24595633; PubMed Central PMCID: PMC3994928.

Ryan AS, Ge Shealinna, Blumenthal JB, Serra MC, Prior SJ, Goldberg AP. Aerobic Exercise and Weight Loss Reduce Vascular Markers of Inflammation and Improve Insulin Sensitivity in Obese Women. Journal of the American Geriatrics Society, 2014: 62(4): 607-14. doi: 10.2337/db14-1771. Epub 2015 Jun 11. PubMed PMID: 26068543; PubMed Central PMCID: PMC4587640.

Prior SJ, Ryan AS, Blumenthal JB, Watson JM, Katzel LI, Goldberg AP. Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Feb 17. pii: glw017. [Epub ahead of print] PubMed PMID: 26888434.

Fink JC, Doerfler RM, Yoffe MR, Diamantidis CJ, Blumenthal JB, Siddiqui T, Gardner JF, Snitker S, Zhan M. Patient-Reported Safety Events in Chronic Kidney Disease Recorded With an Interactive Voice-Inquiry Dial-Response System: Monthly Report Analysis. J Med Internet Res. 2016 May 26;18(5); e125. doi:10.2196/jmir.5203. PubMed PMID: 27230267.

Lutz AH, Blumenthal JB, Landers-Ramos RQ, Prior SJ. Exercise-induced endothelial progenitor cell mobilization is attenuated in impaired glucose tolerance and type 2 diabetes. J Appl Physiol (1985). 2016 May 19:jap.00349. 2016. doi: 10.1152/japplphysiol.00349.2016. [Epub ahead of print] PubMed PMID: 27197857.

Blumenthal JB, Cai S, May C, Scarinzi G, Gernat E, Mordecai KL, Loreck DJ, Brandt NJ, Inscore AI, Intrator O. Dementia Evaluation, Management and Outreach (DEMO): A Novel Program Improves Access, Satisfaction for Patients with Cognitive Complaints. Federal Practitioner (in press).

Awards and Affiliations

Fellow, American College of Physicians