Director, Biochemical Genetics Laboratory
Bressler Research Building, 7-041
Education and Training
1989-1993 B.A., Biochemistry summa cum laude, Phi Beta Kappa, Western Maryland College (now McDaniel College), Westminster, Maryland
1993-1999 Ph.D., Graduate Program in Human Genetics, University of Maryland Baltimore
Post-graduate Education and Training:
1999-2002 Fellow in Clinical Biochemical Genetics (IRTA fellow), Section on Biochemical Genetics, Heritable Disorders Branch, NICHD, National Institutes of Health
2002 Diplomate, American Board of Medical Genetics and Genomics; Clinical Biochemical Genetics
Certificate #2002108; recertified 2013-2023; meeting requirements for Maintenance of Certification
Dr. Strovel, is an associate professor of Pathology at the University of Maryland School of Medicine, where her major academic role has been as Director of the University of Maryland Pathology Associates Biochemical Genetics Laboratory. Dr. Strovel is also involved with medical genetics education, and is very involved with teaching graduate students, medical students, residents, and fellows. She is the Content Lead for Genetics in Foundations, and currently serves on the University of Maryland School of Medicine Pre-Clerkship Curriculum and Curriculum Coordinating committees. After earning her BA in biochemistry from McDaniel College, she pursued her PhD in Human Genetics at the University of Maryland, Baltimore. She completed her post-graduate work as a fellow in Biochemical Genetics at the National Institutes of Health in the National Institute of Child Health and Development and is board-certified in clinical biochemical genetics.
Since joining the faculty in 2002, Dr. Strovel has earned several grants from the Maryland State Department of Health and Mental Hygiene and the National Human Genome Research Institute, has collaborated on several peer-reviewed articles and book chapters and has lectured in Cairo, Egypt. In 2011, she was the recipient of the distinguished Trustee Alumni Award from McDaniel College.
Dr. Strovel is a fellow of the American College of Medical Genetics, a member of the American Society of Human Genetics, and a member of the Society for Inherited Metabolic Disease. Dr. Strovel currently serves as chair of the State Advisory Council on Hereditary and Congenital Disorders for the State of Maryland, is a member of the Course directors' special interest group (CD-SIG) executive committee for the Association of Professors in Human and Medical Genetics (APHMG), serves on the clinical competency committee (CCC) for the NIH Clinical Genetics and Medical Biochemical Genetics residency programs and is a member of the NIH Medical Biochemistry Program Evaluation Committee.
Biochemical and metabolic genetic disorders; newborn screening; quality of genetic testing; medical genetics and genomics education
Pindolia K, Jordan M, Guo C, Matthews N, Mock DM, Strovel E, Blitzer M, Wolf B: Development and characterization of a mouse with profound biotinidase deficiency: A biotin-responsive neurocutaneous disorder. Mol Genet Metab 102(2):161-169, 2011.
Hoffman JD, Greger V, Strovel ET, Blitzer MG, Umbarger MA, Kennedy C, Bishop B, Saunders P, Porreca GJ, Schienda J, Davie J, Hallam S, Towne C. Next-Generation DNA Sequencing of HEXA: a step in the right direction for carrier screening. Molecular Genetics & Genomic Medicine 1(4):260-268, 2013
Schillaci L, Greene C, Strovel E, Rispoli-Joines J, Spector E, Woontner M, Scharer G, Enns G, Gallagher R, Zinn A, McCandless S, Hoppel C, Goodman S, and Bedoyan J.The M405V allele of the glutaryl-COA dehydrogenase gene is common among glutaric aciduria type I (GA-I) low excretors. Mol Genet Metab: 119 (1-2): 50-56, 2016
Langley K, Strovel E, and Vergano S. Critical newborn screens in double heterozygotes of inborn errors of metabolism - A clinical report and recommendations. Int. J. NeonatalScreen 2(4): 1-12, 2016.
Strovel E, Cowan TM, Scott AI, and Wolf B. Laboratory diagnosis of biotinidase deficiency, 2017 update, a Technical Standard and Guideline of the American College of Medical Genetics and Genomics (ACMG). Genetics in Medicine 19 (10), 2017.
Huizing M, Saranjarajan R, Strovel E, Zhao Y, GahlWA, and Boissy RE. AP-3 mediates Tyrosinase but not TRP-1 trafficking in human melanocytes. Mol Biol Cell 12: 2075-2085, 2001.
Huizing M, Scher CD, Strovel E, Fitzpatrick DL, Hartnell L, Anikster Y, and Gahl WA. Nonsense mutations in ADTB3A cause complete deficiency of the beta3A subunit of adaptor complex-3 and severe Hermansky-Pudlak syndrome type 2. Pediatr Res 51: 150-158, 2002.
Kleta R, Aughton DJ, Rivkin MJ, Huizing M, Strovel E, Anikster Y, Orvinsky E, Natowicz M, Krasnewich D, Gahl WA. Biochemical and Molecular Analyses of Infantile Free Sialic Acid Storage disease in North American Children. Am J Med Genet 120A: 28-33, 2003.
Cowan, TM and Strovel, ET. Management and quality assurance in the biochemical genetics laboratory. Curr Protoc Hum Genet. 2008 Oct; Chapter 17:Unit 17.7.
McHugh D, Cameron C, Abdenur J, Strovel E, Zakowicz M. Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: A worldwide collaborative project. Genet Med 13:230-254, 2011.
Emadi A, Law JY, Strovel ET, Lapidus RG, Jeng LJB, Lee M, Blitzer MG, Carter-Cooper BA, Sewell D, Van Der Merwe I, Philip S, Imran M, Yu SL, Li H, Amrein PC, Duong VH, Sausville EA, Baer MR, Fathi AT, Singh Z, and Bentzen SM. Asparaginase Erwinia chrysanthemi effectively depletes plasma glutamine in adult patients with relapsed/refractory acute myeloid leukemia. Cancer Chemother Pharmacol 81 (1): 217-222, 2018.
2007 Professional Achievement Award, McDaniel College, Westminster, Maryland
2011 Trustee Alumni Award, McDaniel College, Westminster, Maryland
2012 Invited Panelist “Women in Leadership”, McDaniel College, Westminster, Maryland
2015 Invited Panelist “Finding Academic Positions”, NIH Career Symposium, National Institutes of Health, Bethesda, Maryland
2006-present NHGRI Biochemical Genetics Training Support for Fellows NHGRI, NIH, Bethesda, Maryland
2012-present “For the Family and the Medical Home: Integrated Clinical Services for Children with Special Health Care Needs” Maryland Dept. of Health and Mental Hygiene, Office of Hereditary Disorders
National Committee Service
2006-present Co-Coordinator, International Tay-Sachs Testing: Quality Control and Data Collection Center, National Tay-Sachs and Allied Diseases Association, Inc.
2009 Member, Clinical Laboratory Improvement Advisory Committee (CLIAC) Biochemical Genetics Testing Workgroup
2010 Biochemical Genetics Certification Examination Book Review Committee, American Board of Medical Genetics
2012-2016 Laboratory QA/QC Committee, American College Medical Genetics
2012 Item Writer for Clinical Biochemical Genetics Examination, American Board of Medical Genetics
2012 Biochemical Genetics Certification Examination Book Review Committee, American Board of Medical Genetics
2014-present Member, State Advisory Council on Hereditary and Congenital Disorders, State of Maryland (appointed January 2014)
2014 Item Writer for Clinical Biochemical Genetics Examination, American Board of Medical Genetics and Genomics
2014 Biochemical Genetics Certification Examination Book Review Committee, American Board of Medical Genetics and Genomics
2014-present American Board of Medical Genetics and Genomics Accreditation Committee
2014 Program Evaluation Committee of the NIH Medical Genetics & Genomic Medicine Residency Training Program
2015 Chair, Lysosomal Enzyme Testing Guideline Committee, American College Medical Genetics
2015-present Inspector, Clinical Biochemical Genetics, College of American Pathology (CAP)
2015 Abstract Reviewer, Metabolic Disorders, 2015 American Society of Human Genetics (ASHG) Annual Meeting
2015-present Competency Committee (CCC) for the NIH Clinical Genetics and Medical Biochemical Genetics residency programs
2016 NIH Medical Biochemistry Program Evaluation Committee
2016 Chair, Revision of “Technical standards and guidelines for the diagnosis of biotinidase deficiency” Committee, American College Medical Genetics and Genomics
2002-present American Society of Human Genetics; Regular member
2003-present Society of Inherited Metabolic Disorders; Regular member
2005-present Fellow, American College of Medical Genetics and Genomics