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Nicholas P. Pietris, MD

Academic Title:

Associate Professor

Primary Appointment:


Additional Title:

Pediatric Cardiologist


110 South Paca Street, 7th Floor

Phone (Primary):




Education and Training

2001               B.S., Biochemistry, State University of New York at Stony Brook                                                            

2005               M.D., State University of New York at Buffalo, School of Medicine and Biomedical Sciences     

2005-2006     Internship, Pediatrics, Yale New Haven Hospital

2006-2008     Residency, Pediatrics, Yale New Haven Hospital

2008-2011     Fellowship, Pediatric Cardiology, Yale New Haven Hospital

2011-2013     Fellowship, Advanced Cardiovascular Imaging, Pediatric Cardiology, Medical University of South Carolina


Dr. Pietris is a pediatric cardiologist who specializes is non-invasive cardiac imaging and cardiopulmonary exercise stress testing. After completing his undergraduate and medical studies (Bachelor of Science in Biochemistry, SUNY Stony Brook and Medical Doctorate, SUNY Buffalo) he completed a residency in pediatrics and fellowship in pediatric cardiology at Yale New Haven Hospital. There, his research involved non-invasive imaging using ultrasound and CTA (computed tomographic angiography) of small animal tissue-engineered vascular grafts which were being studied in order to develop similar grafts for use in congenital cardiac surgery. After completing his primary fellowship at Yale, he continued his training and research in advanced pediatric cardiac imaging within the Children's Heart Program at the Medical University of South Carolina (MUSC).  Dr. Pietris’ clinical focus includes general pediatric cardiology, cardiopulmonary exercise stress testing and cardiac non-invasive imaging (fetal, transthoracic and transesophageal echocardiography, cardiac CTA/MRI).   Dr. Pietris’ academic interests include non-invasive cardiac imaging (echocardiography, MRI, CTA), cardiopulmonary exercise testing, in addition to exploring the potential applications of stem cell therapy in congenital heart disease.  Dr. Pietris is board certified in pediatrics and pediatric cardiology. He is a member of the American Heart Association, American College of Cardiology and the American Society of Echocardiography.

Research/Clinical Keywords

Clinical and research focus are in the area of congenital heart disease and acquired pediatric cardiovascular disease

Highlighted Publications

Wehman, B., Sharma, S., Pietris, N., Mishra, R., Siddiqui, O. T., Bigham, G., & Griffith, B. (2016). Mesenchymal stem cells preserve neonatal right ventricular function in a porcine model of pressure overload. American Journal of Physiology-Heart and Circulatory Physiology, 310(11), H1816-H1826.

Wehman, B.,  Stafford, K., Bittle, G, Zachary N. Kon, Charles F. Evans, Rajagopal, K, Pietris N, Sunjay K, and  Griffith, B. "Modern outcomes of mechanical circulatory support as a bridge to pediatric heart transplantation." The Annals of thoracic surgery 101, no. 6 (2016): 2321-2327.
Hibino N, Mejias D, Pietris N, Dean E, Yi T, Best C, Shinoka T, Breuer CK. The innate immune system contributes to tissue-engineered vascular graft performance. FASEB Journal. 2015. Published online before print. 10.1096/fj.14-268334
Dyer KT, Hlavacek AM, Meinel FG, De Cecco CN, McQueston AD, Schoepf UJ, Pietris NP.  Imaging in congenital pulmonary vein anomalies: the role of computed tomography. Pediatric Radiology. 2014 (44):1158-1168. DOI 10.1007/s00247-014-3044-7
Chowdhury SM, Hijazi ZM, Rhodes JF, Kar S, Makkar R, Mullen M, Cao QL, Mandinov L, Buckley J, Pietris NP, Shirali GS. Changes in Speckle-Tracking Echocardiography Measures of Ventricular Function after Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonary Position. Echocardiography. 2014. doi: 10.1111/echo.12700

Additional Publication Citations

Pietris N, Seashore MR. Newborn Screening. In: Talwalkar JS, Fenick AM, eds. Yale Primary Care Pediatrics Curriculum, 1st-9th Editions. 2006-2015. Available from