Research/Clinical Keywords
Infectious Diseases, Vaccines R&D, Vaccine Design, Immunology, Microbiology, Parasitology, Cancer, Malaria, Enteric Mucosal Pathogens, Viruses, Functional Assays, Host-Pathogen Interactions, Public Health, Climate Change, Pre-clinical, Clinical, Liposomes, Nanoparticles, Global Health
Highlighted Publications
Oakley MS, Malla P, Hayashi CTH, Majam V, Chorazeczewski JK, Okoth WA, Meredith S, KuKuruga M, Akue A, Rotstein DS, Kumar S. 2025. CD47-mediated selective accumulation of mature Ly49h+ NK cells to the brain associates with the pathogenesis of cerebral malaria in mice, The Journal of Immunology, Volume 214, Issue 10, October 2025, Pages 2676-2687, https://doi.org/10.1093/jimmun/vkaf151
Okoth WA, Ho M, Zaman M, Cooper E, Som P, Burgess M, Walton M, Nevagi RJ, Beattie L, Murphy D, Stanisic DI, Good MF. 2023. A CAF01-adjuvanted whole asexual blood-stage liposomal malaria vaccine induces a CD4+ T-cell-dependent strain-transcending protective immunity in rodent models. mBio 14:e02547-23. https://doi.org/10.1128/mbio.02547-23
Torrez Dulgeroff LB, Oakley MS, Tal MC, Yiu YY, He JQ, Shoham M, Majam V,
Okoth WA, Malla P, Kumar S, Weissman IL.
2021. CD47 blockade reduces the pathologic features of experimental cerebral malaria and promotes survival of hosts with
Plasmodium infection,
Proc. Natl. Acad. Sci. U.S.A. 118 (11) e1907653118,
https://doi.org/10.1073/pnas.1907653118
Oakley MS, Chorazeczewski JK, Aleshnick M, Anantharaman V, Majam V, Chawla B, Myers TG, Su Q, Okoth WA, Takeda K, Akue A, Kukuruga M, Aravind L, Kumar S. 2018. TCRβ-expressing macrophages induced by a pathogenic murine malaria correlate with parasite burden and enhanced phagocytic activity. PLoS ONE 13(7): e0201043. https://doi.org/10.1371/journal.pone.0201043
Chorazeczewski JK, Aleshnick M, Majam V, Okoth WA, Kurapova R, Akue A, Kukuruga M, Kumar S, Oakley MS. 2018. TCRβ Combinatorial Immunoreceptor Expression by Neutrophils Correlates with Parasite Burden and Enhanced Phagocytosis during a Plasmodium berghei ANKA Malaria Infection. Infect Immun 86:10.1128/iai.00899-17. https://doi.org/10.1128/iai.00899-17
Okoth WA, Dukes EJ, Sullivan DJ. 2018. Superior Pyronaridine Single-Dose Pharmacodynamics Compared to Artesunate, Chloroquine, and Amodiaquine in a Murine Malaria Luciferase Model. Antimicrob Agents Chemother 62:10.1128/aac.00394-18. https://doi.org/10.1128/aac.00394-18
Truran S, Weissig V, Ramirez-Alvarado M, Franco, DA, Burciu, C, Georges J, Murarka S, Okoth WA, Schwab S, Hari P, Migrino RQ. 2014. Nanoliposomes protect against AL amyloid light chain protein-induced endothelial injury. Journal of Liposome Research, 24(1), 69–73. https://doi.org/10.3109/08982104.2013.838258
