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Fu M. Hu, PhD

Academic Title:


Primary Appointment:


Secondary Appointment(s):

Epidemiology & Public Health, Surgery

Additional Title:

(Peter Hu)


11 S. Paca Street, LL, 1

Phone (Primary):

(410) 328-7264

Phone (Secondary):

(410) 328-7265


(410) 328-7230

Education and Training

1984 - BS, Electrical Engineering, Shanghai University, China
1992 - MS, Computer Science, University of Maryland Baltimore County
2013 - PhD, Computer Science, University of Maryland Baltimore County

Highlighted Publications

Shackelford S, Yang S, Hu P, Miller C, Anazodo A, Galvagno S, Wang Y, Hartsky L, Fang R, Mackenzie C. Predicting blood transfusion using automated analysis of pulse oximetry signals and lab values. J Trauma Acute Care Surg. 2015 Oct;79 (4 Suppl 2):S175-80  PMID: 26406427

Bonds BW, Yang S, Hu PF, Kalpakis K, Stansbury LG, Scalea TM, Stein DM. Predicting secondary insults after severe traumatic brain injury. J Trauma Acute Care Surg. 2015 Jul;79(1):85-90. PMID: 26091319

Bonds BW, Hu P, Li Y, Yang S, Colton K, Gonchigar A, Cheriyan J, Grissom T, Fang R, Stein DM. Predictive value of hyperthermia and intracranial hypertension on neurological outcomes in patients with severe traumatic brain injury. Brain injury. 2015;29(13-14):1642-7.

Yang S, Hu PF, Anazodo A, Gao C, Chen H, Wade C, Hartsky L, Miller C, Imle C, Fang R, Mackenzie CF. Trends of Hemoglobin Oximetry: Do They Help Predict Blood Transfusion During Trauma Patient Resuscitation? Anesthesia and analgesia. 2015;122(1):115-25.

Dezman Z, Hu E, Hu PF, Yang S, Stansbury LG, Fang R, Miller C, Mackenzie CF. Computer Modelling Using Prehospital Vitals Predicts Transfusion and Mortality. Prehospital Emergency Care. 2016. Accepted 1/7/2016

Additional Publication Citations

Selected peer-review articles among 65 papers

Hu P, Xiao Y, Ho D, Mackenzie CF, Hu H, Voigt R, Martz D. Advanced Visualization Platform for Surgical Operating Room Coordination: Distributed Video Board System. Surgical Innovation. 13(2):129-135. 2006 PMID:17012154

Mackenzie CF, Hu P, Fausboll C, Nerlich M, Benner T, Gagliano D, Whitlock W, Lam D, Xiao Y. Challenges to remote emergency decision-making for disasters or Homeland Security. Cognition, Technology, and Work. 9(1):15-24. 2007

Mackenzie CF, Xiao Y, Hu P, Seagull FJ, Fitzgerald M. Video as a Tool for Improving Tracheal Intubation Tasks for Emergency Medical and Trauma Care. Annals of Emergency Medicine 50(4):436-42. 2007 PMID:17881317

LaMonte MP, Bahouth MN, Xiao Y, Hu P, Baquet CR, Mackenzie CF. Outcomes from a comprehensive stroke telemedicine program. Telemedicine and E-Health 14(4):339-44. 2008 PMID:18570562

Xiao Y, Dexter F, Hu F, Dutton R. Usage of Distributed Displays of Operating Room Video when Real-Time Occupancy Status was Available . Anesthesia and Analgesia; 106(2):554-560. 2008 PMID:18227316

Xiao Y, Hu P, Moss J, de Winter J, Venekamp D, Mackenzie CF, Seagull FJ, Perkins S. Opportunities and challenges in improving surgical work flow. Cognition, Technology & Work, 10:313-321. 2008

Kim Y-J, Xiao Y, Hu P, Dutton RP. Staff Acceptance of Video Monitoring for Coordination: A Video System to Support Perioperative Situation Awareness. Journal of Clinical Nursing, 18(16):2366-71, 2009. PMID:19583666

Sen A, Xiao Y, Lee S, Hu P, Dutton RP, Haan J, OConnor J, Pollak AP, Scalea T. Daily Multi-Disciplinary Discharge Rounds in a Trauma Center: A Little Time, Well Spent. Journal of Trauma, 66(3):880-7. 2009 PMID:19276768

Gurses AP, Xiao Y, Hu P. User-designed information tools to support communication and care coordination in a trauma hospital. Journal of Biomedical Informatics 42(4):667-77, 2009 PMID:19298868

Mackenzie C, Donohue J, Wasylina P, Cullum W, Hu P, Lam DM. How will military/civilian coordination work for reception of mass casualties from overseas? Pre hospital Disaster Med. 2009 Sep-Oct;24(5):380-8. 2009 PMID:20066638

Kahraman S, Hu P, Xiao Y, Dutton RP, Aarabi B, Stein DM, Scalea TM. Pressure-time dose of automated ICP and CPP data predicts outcomes in severe TBI. J Trauma. 2010;69:110-8. PMID:20038855

Kahraman S, Dutton RP, Hu P, Stansbury L, Xiao Y, Stein DM, Scalea TM. Heart rate and pulse pressure variability are associated with intractable intracranial hypertension after severe traumatic brain injury. J Neurosurg Anesthesiol. 2010; 22:296-302. PMID:20622688

Kahraman S, Hu P, Stein DM, Stansbury L, Dutton RP, Hess JR, Scalea TM. Dynamic three-dimensional scoring of cerebral perfusion pressure and intracranial pressure provides a Brain Trauma Index that predicts outcome in patients with severe traumatic brain injury. J Trauma. 2011. J Trauma. 2011;70(3):547-53 PMID:21610341

Stein DM, Hu P, Brenner M, Sheth K, Liu K, Xiong W, Aarabi B, Scalea TM. Brief Episodes of Intracranial Hypertension and Cerebral Hypoperfusion are Associated with Poor Functional Outcome Following Severe Traumatic Brain Injury . Journal of Trauma. 2011 Aug;71(2):364,73; discussion 373-4 PMID:21825940

Woodford M, Mackenzie C, DuBose J, Hu P, Kufera J, Hu E, Dutton R, Scalea T. Continuously Recorded SPO2 and Pulse Rate During Pre-hospital Transport Outperform Initial Measurement in Prediction of Mortality after Trauma J Trauma Acute Care Surg. 2012 Apr;72(4):1006-12. PMID:22491618

Brenner M, Stein DM, Hu P, Aarabi B, Sheth K, Scalea TM. Traditional systolic blood pressure targets underestimate hypotension-induced secondary brain injury. J Trauma. 2012 May;72(5):1135-9 PMID:22673237

Stein DM, Hu P, Chen H, Stansbury LG, Yang S, Scalea TM. Computational "gene-mapping" to analyze continuous automated physiologic monitoring data in neuro-trauma intensive care. J Trauma Acute Care Surg. 2012 Aug;73(2):419-25 PMID:22846949

Diamantidis C, Zuckerman M, Fink W, Hu P, Yang S, Fink JC. Usability of a chronic kidney disease educational Web site targeted to patients and their family members Clinical Journal of the American Society of Nephrology 2012 Oct;7(10):1553-60 PMID22798537

Brenner M, Stein D, Hu P, Kufera J, Wooford M, Scalea T. Association Between Early Hyperoxia and Worse Outcomes After Traumatic Brain Injury. Arch Surg. 2012 Jul 16:1-5. PMID:22801994

Sheth KN, Stein DM, Aarabi B, Hu P, Kufera JA, Scalea TM, Hanley DF. Intracranial Pressure Dose and Outcome in Traumatic Brain Injury. Neurocrit Care. 2013 Feb;18(1):26-32. [Online 2012 Oct 9]. PMID:23055087

Stein D, Brenner M, Hu P, Yang S, Hall E, Stansbury L, Menaker J, Scalea T, Timing of Intracranial Hypertension following Severe Traumatic Brain Injury. Neurocrit Care. 2013 Jun;18(3):332-40. doi: 10.1007/s12028-013-9832-3.PMID:23494545

Dale Y, Dutton R, Hu P, Chang Y, Brown C, Chen H, Grissom T, Kufera J, Scalea T. Effect of Video Laryngoscopy on Trauma Patient Survival: A Randomized Controlled Trial. J Trauma Acute Care Surg. 2013 Aug;75(2):212-9  PMID: 23823612

Effect of Video Laryngoscopy on Trauma Patient Survival: A Randomized Controlled Trial. J Trauma Acute Care Surg. 2013 Jul 2. [Epub ahead of print] PMID: 23823612

Hu P, Galvagno SM, Sen A, Dutton RP, Handley C, Shckelford S, Pasley JD, Mackenzie CF. Identification of dynamic prehospital changes with continuous vital signs acquisition. Air Med J. 2014 Jan-Feb;33(1):27-33. PMID: 24373474

Colton K, Dinardo T, Hu P, Xiong W, Hu E, Reeds G, DuBose J, Stansbury LG, Mackenzie CF, Chiu W, Miller C, Fang R, Stein D, Scalea T, ONPOINT Study Group. â?oFull of sound and fury, signifying nothing:â? The burden of transient non-critical monitor alarms in a trauma resuscitation unit. J Trauma Nurs. 2013 Oct-Dec;20(4):184-8. PMID: 24305079

Diamantidis CJ, Fink W, Yang S, Zuckerman M, Ginsberg J, Hu P, Xiao Y, Fink J.Directed use of the Internet for health information by patients with chronic kidney disease (CKD): results from Saf e Kidney Care. J Med Internet Res. 2013 Nov 15;15(11) PMID: 24240617

Performance Assessment in Airway Management Training for Nonanesthesiology Trainees: An Analysis of 4,282 Airway Procedures Performed at a Level 1 Trauma Center. J of Anesthesiology. 2014 Jan;120(1):185-95. PMID: 24201030

K Colton , S Yang, PF Hu, HH Chen, B Bonds, TM Scalea, DM Stein. Intracranial pressure response after pharmacologic treatment of intracranial hypertension. J of Trauma Acute Care Surg. 2014 Jul;77(1):47-53;PMID: 24977754

C Mackenzie, Y Wang, PF Hu, SY. HH Chen, G Hagegeorge, LY Stansbury, S Shackelford, ONPOINT Study Group Automated prediction of early blood transfusion in trauma patients J of Trauma Acute Care Surg. 2014 Jun;76(6):1379-85. PMID: 24854304

K Colton, S Yang, PF Hu, HH Chen, LG Stansbury, TM Scalea, DM Stein. Responsiveness to therapy for increased intracranial pressure in traumatic brain injury is associated with neurological outcome. Injury. 2014 Dec;45(12):2084-8. PMID: 25304159

C Mackenzie, C Gao, PF Hu, A Anazodo, H Chen, T Dinardo, PC Imle, L Hartsky, C Stephens, J Menaker, Y Fouche, K Murdock, S Galvagno, R Alcorta, S Shackelford Comparison of decision-assist and clinical judgment of experts for prediction of life saving interventions. Journal of Shock 2014 Nov 26. PMID: 25394243

K Colton, S Yang, PF Hu, HH Chen, B Bonds, LG Stansbury, TM Scalea, DM Stein Pharmacologic Treatment Reduces Pressure Times Time Dose and Relative Duration of Intracranial Hypertension. J Intensive Care Med. 2014 Oct 15.PMID: 25320157

A Anazodo, S Murthi, K Frank, PF Hu, L Hartsky, PC Imle, C Stephens, J Menaker, C Miller, J Pasley, C Mackenzie. Assessing Trauma-Care Provider Judgment in the Prediction of Need for Life-Saving Interventions. Injury. 2015 May;46(5):791-7 PMID: 25541418

K. Kalpakis, S. Yang, P.F. Hu, C. F. Mackenzie, L.G. Stansbury, D.M. Stein, T.M. Scalea, Permutation entropy analysis of vital signs data for outcome prediction of patients with severe traumatic brain injury, Computers in Biology and Medicine, 2015 Jan;56:167-74. PMID: 25464358

Galvagno SM, Hu P, Yang S, Gao C, Hanna D, Shackelford S, Mackenzie CF. Accuracy of continuous noninvasive hemoglobin monitoring for the prediction of blood transfusions in trauma patients. J Clin Monit Comput. 2015 Mar 10; accepted for publication on 23 Feb 2015. PMID: 25753142

Research Interests

Utilizing real-time patient field and admission vital signs data to predict life saving interventions such as emergency blood transfusion, intubation, and emergency surgery. Developing realtime advanced machine learning algorithms to predict near and long term trauma patient outcomes. In hospital and mobile telemedicine applications for rapid assessment of trauma patient status for triage and treatment.

Grants and Contracts

Clinical Study of Resuscitative Endovascular Ballon Occlusion of the Aorta (REBOA) for Severe Pelvic Fracture and Intra-abdominal Hemorrhagic Shock using Continuouse Vital Signs
Role: Co-Investigator
Period: 2/2015-2/2017

Assessing the Accuracy and the Impact of Standard-Practice Ventricular Drainage on Intracranial Pressure Measurements following Traumatice Brain Injury
Role: Co-Principle Investigator
Period: 9/2015-9/2018

Transport Assessment for Critical Traumatic Injuries Calculator
Role: Co-Principle Investigator
Period: 10/15-10/2017

Use of Prehospital Point-of-Care Testing and Tissue Oximetry to Facilitate the Early Diagnosis of Hemorrhagic Shock, Need for Life-Saving Interventions and Prediction of Clinical Course
Role: Co-Investigator
Period: 9/2015-8/2017

Developing Reliable Telemedicine Platform with unreliable and Limited Communication Bandwidth
Role: Principle Investigator
Period: 11/2015-11/2016

Validation of Automated Prediction of Blood Product Needs Algorithm Processing Continuious Non-Invasive Vital Signs Streams
Role: Principle Investigator
Period: 9/2015-9/2016

Evaluation of Handoff Outcomes in a Multi-Site Continuum of Care Exercise
Role: Co-Principle Investigator
Period: 10/2015-9/2016

Development and Validation of Prototype Continuouse-Real Time Vital Signs Monitoring System “CCATT Viewer”
Role: Principle Investigator
Period: 9/2014-6/2016

Reduction of UMMC-ICU alarms
Role: Principle Investigator
Period: 7/2014-6/2016

Comparison of Automated and Manual Recording of Brief Episodes of Intracranial Hypertension and Cerebral Hypoperfusion. (ICP Comparison)
Role: Principle Investigator
Period: 8/2013-8/2014

Autonomous Critical Care Systems  (ACCS) ONR N00014-12-C-0120
Role: Co-Investigator
Period: 6/2012-12/2014

Predicting casualty blood product needs using pre-hospital vital signs (ONPOINT II)
Role: Co-Investigator
Period: 6/2012-5/2014

Use of Performance Measures to Evaluate, Document Competence and Deterioration of ASSET Surgical Skills
Role: Co-Investigator
Period: 2/2013-2/2016

"Fit-to-fly" biomarkers after severe TBI
Role: Co-Investigator
Period: 7/2013-2/2016

Continuous non-invasive monitoring and the development of predictive triage indices for outcome following trauma (ONPOINT I)
Role: Co-Investigator
Period: 4/2014-3/2015