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Daniel M. Harrison, MD

Academic Title:

Associate Professor

Primary Appointment:


Administrative Title:

Director of the Neuro-Immunology & Multiple Sclerosis Division


110 S Paca 03-072

Phone (Primary):




Education and Training

Dr. Harrison received his medical degree from the Albert Einstein College of Medicine in the Bronx, New York and completed a neurology residency at the Columbia University Medical Center in New York City, where he was chief resident. He holds board certification in neurology from the American Board of Psychiatry and Neurology and he received subspecialty training by completing a fellowship in neuroimmunology and neuroinfectious disease at the Johns Hopkins University School of Medicine.


Dr. Harrison has been an Assistant Professor of Neurology at the University of Maryland School of Medicine since 2015. Prior to that he was on facult at the Johns Hopkins University School of Medicine from 2010 through 2015. Dr. Harrison directs an active research program focused on the development and validation of new techniques for imaging of the brain and spinal cord for application to multiple sclerosis research and clinical trials. Dr. Harrison's research program is currently focused on utilization of novel MRI techniques, including high-field, 7-tesla MRI for visualization of cortical pathology, neurodegeneration, and meningeal inflammation in multiple sclerosis. Dr. Harrison is also an active investigator in the Maryland Center for MS clinical trials program.

Research/Clinical Keywords

Multiple Sclerosis, MRI, Neuroimaging, Clinical Trials

Highlighted Publications

  1. Harrison DM, Caffo B, Shiee N, Farrell JAD, Bazin PL, Farrell SK, Ratchford JN, Calabresi PA, Reich DS.  Longitudinal changes in diffusion-tensor-based quantitative MRI in multiple sclerosis.  Neurology.  2011;Jan 11;76(2):179-86.
  2. Harrison DM, Gladstone DE, Hammond E, Cheng J, Jones RJ, Brodsky RA, Kerr D, McArthur JC, Kaplin A.  Treatment of relapsing-remitting multiple sclerosis with high-dose cyclophosphamide induction followed by glatiramer acetate maintenance.  Multiple Sclerosis.  2012 February;18(2):202-209.
  3. Harrison DM, Oh J, Roy S, Wood ET, Whetstone A, Seigo M, Jones CK, Pham D, van Zijl P, Reich DS, Calabresi PA. Thalamic Lesions in multiple sclerosis by 7T MRI: clinical implications and relationship to cortical pathology. Multiple Sclerosis 2014: 21(9):1139-50.
  4. Harrison DM, Roy S, Oh J, Izbudak I, Pham D, Courtney S, Caffo B, Jones CK, van Zijl P, Calabresi PA. Association of cortical lesion burden on 7T MRI with cognition and disability in multiple sclerosis. JAMA Neurology 2015; 72(9):1004-12.
  5. Harrison DM, Li X, Liu H, Jones CK, Caffo B, Calabresi PA, van Zijl P. Lesion heterogeneity on high-field susceptibility MRI is associated with multiple sclerosis severity. Am J Neuroradiol 2016; 37(8):1447-53. PMID: 26939635

Additional Publication Citations

For an up to date listing of Dr. Harrison's publications visit:

Research Interests

Dr. Harrison's research focuses on the development, validation, and utilization of novel MRI techniques, including ulta high-field, 7-tesla MRI for visualization of aspects of MS not readily visualized on standard MRI. This includes cortical pathology, neurodegeneration, and meningeal inflammation.

Clinical Specialty Details

Dr. Harrison specializes in the diagnosis and treatment of patients with multiple sclerosis and other autoimmune disorders of the brain, spinal cord, and optic nerves.

Links of Interest