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Jennifer A. Snyder, PhD

Academic Title:

Instructor

Primary Appointment:

Medicine

Location:

HSF I, Room 480

Phone (Primary):

(410) 706-5330

Fax:

(410) 706-6205

Education and Training

University of Rochester, B.S., Microbiology, 2000

University of Maryland School of Medicine, Ph.D., Microbiology and Immunology, 2004

Biosketch

Dr. Snyder’s research focus during her training was in the field of infectious diseases and bacterial pathogenesis. Since joining the Center for Vaccine Development in 2005, Dr. Snyder has specialized in research program management. With her combined background as both a scientist with research experience, and as an administrator with programmatic management proficiencies, she has managed several large multi-institutional, multi-project research programs. She was the Associate Director for the Middle Atlantic Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research Program (MARCE) and was PI of the MARCE Career Development and Training Program from 2005 - 2015.

She currently serves as the Associate Director for the Enteric Center of Excellence for Translational Research (Enteric CETR) and the Associate Director of Research for the Cooperative Center on Human Immunology (CCHI).

Research/Clinical Keywords

Vaccine development and testing, emerging infectious diseases, biodefense, immunoprophylactic strategies, enteric diseases, bacterial and protozoal pathogens, mucosal immunity, enteric vaccines, microbiota, human and animal models.

Highlighted Publications

Sinha P, Snyder JA, Kim EY, Moudgil KD. The major histocompatibility complex haplotypes dictate and the background genes fine-tune the dominant versus the cryptic response profile of a T cell determinant within a native antigen: Relevance to disease susceptibility and vaccination. Scan. J. Immun. 2007; 65:158-65.

Snyder JA, Lloyd AL, Lockatell CV, Johnson DE, Mobley HLT. Role of phase variation of type 1 fimbriae in a uropathogenic Escherichia coli cystitis isolate during urinary tract infection. Infect Immun. 2006; 74:1387-93.

Snyder JA, Haugen BJ, Lockatell CV, Maroncle N, Hagan EC, Johnson DE, Welch RA, Mobley HLT. Coordinate expression of fimbriae in uropathogenic Escherichia coli. Infect Immun. 2005; 73:7588-96.

Snyder JA, Haugen BJ, Buckles EL, Lockatell CV, Johnson DE, Donnenberg MS, Welch RA, Mobley HLT. Transcriptome of uropathogenic Escherichia coli during urinary tract infection. Infect Immun. 2004; 72:6373-81. P

Griswold AR, Chen YM, Snyder JA, Burne RA. Characterization of the arginine deiminase operon of Streptococcus rattus FA-1. Appl Environ Microbiol. 2004; 70:1321-7.

Additional Publication Citations

Dong Y, Chen YY, Snyder JA, Burne RA. Isolation and molecular analysis of the gene cluster for the arginine deiminase system from Streptococcus gordonii DL1. Appl Environ Microbiol. 2002; 68:5549-53.

Gunther NW, Snyder JA, Lockatell V, Blomfield I, Johnson DE, Mobley HLT. Assessment of virulence of uropathogenic Escherichia coli type 1 fimbrial mutants in which the invertible element is phase-locked on or off. Infect Immun. 2002; 70:3344-54.

Chen YY, Betzenhauser MJ, Snyder JA. Pathways for lactose/galactose catabolism by Streptococcus salivarius. FEMS Microbiol Lett.. 2002; 209:75-9.

Research Interests

Dr. Snyder specializes in research program management, and strives to establish successful administrative and programmatic management techniques to enhance multiple programs. She enjoys monitoring such a diverse research portfolio and fostering interactions among scientists with such varied areas of expertise. Dr. Snyder remains interested in shaping the research priorities, scientific goals, and programmatic priorities for these programs. Another area of particular interest is in training and development, where she organizes training opportunities for the program investigators and manages initiatives to add new projects to the research portfolio.

Under the MARCE Program (2005-2015), Dr. Snyder’s research interests included the development and testing of vaccines, diagnostics and therapeutics against emerging infectious diseases and agents of biowarfare. Her research interests under the Enteric CETR program focus on the development of immunoprophylactic strategies to prevent enteric disease caused by several important bacterial and protozoal pathogens. Her interests under the CCHI program include studying the interplay of mucosal immunity, enteric vaccines, and microbiota in humans and in animal models.

Grants and Contracts

Myron M. Levine, M.D., D.T.P.H. (PI)
Role: Enteric CETR Associate Director of Research
1 U19 AI109776
03/01/14 - 02/28/19
NIH/NIAID
Enteric Center of Excellence for Translational Research (Enteric CETR). Immunoprophylactic strategies to control emerging enteric infections.

Marcelo B. Sztein, M.D. (PI)
Roles: CCHI Associate Director of Research and Pilot Project Core Co-Investigator
2 U19 AI082655
06/01/14 - 05/31/19
NIH/NIAID
Cooperative Center on Human Immunology (CCHI). Mucusal and systemic immunity, vaccines and microbiota interplay in humans.