Skip to main content

Miriam K. Laufer, MD

Academic Title:

Professor

Primary Appointment:

Pediatrics

Secondary Appointment(s):

Medicine, Epidemiology & Public Health

Administrative Title:

Associate Director for Malaria Research

Location:

HSF1, Room 480

Phone (Primary):

(410) 706-8695

Fax:

(410) 706-2999

Education and Training

Dr. Miriam Laufer is Professor of Pediatrics, Medicine, Epidemiology and Public Health, and Faculty of the graduate program in Microbiology and Immunology at the University of Maryland School of Medicine. She received her medical degree at the University of Pennsylvania and completed her residency in pediatrics at Babies and Children’s Hospital of New York (now New York Children’s Hospital) of Columbia University. She completed fellowships in pediatric infectious diseases at Johns Hopkins University and in malaria research at the Center for Vaccine Development at the University of Maryland. She received her MPH from the Bloomberg School of Public Health at Johns Hopkins University.

Biosketch

Dr. Laufer is a pediatric infectious disease specialist, with a primary research interest in malaria and global child health. She has conducted research, clinical care and professional education in resource-limited countries in Africa and Asia, and has dedicated nearly two decades to working in Malawi. She and her research team use clinical and laboratory research to develop and evaluate interventions to decrease the burden of malaria in sub-Saharan Africa. She currently serves as Principal Investigator for clinical trials, epidemiological studies and a Fogarty training grant, that support her collaboration with colleagues throughout the US, Europe and Africa.

Her current research focuses on malaria during pregnancy and its impact on infants,  the interaction between HIV and malaria and identifying reservoirs of malaria transmission. Her laboratory at the University of Maryland explores the application of molecular epidemiology tools to address critical issues related to malaria pathogenesis, disease burden and drug resistance.

Dr. Laufer directs the Malaria Research Program at the Center for Vaccine Development and Global Health. ‌‌The Malaria Research Program aims to support global malaria eradication efforts by developing and deploying innovative tools for improved malaria treatment, prevention and surveillance. Recognizing that progress requires interdisciplinary and international partnerships now and in the future, we work in collaboration with researchers across the globe  and focus on training  young scientists and clinical investigators to build research capacity both in the US and in malaria-endemic countries

Research/Clinical Keywords

Malaria, Pediatric Infectious Diseases, Global Health, Pregnancy, Maternal-Child Health, HIV Co-infection, School age children, Public Health.

Highlighted Publications

Divala TH, Mungwira RG, Mawindo PM, Nyirenda OM, Kanjala M, Ndaferankhande M, Tsirizani LE, Masonga R, Muwalo F, Potter GE, Kennedy J, Goswami J, Wylie BJ,  Ndovie L, Mvula P,  Mbilizi Y, Tomoka T, Laufer MK. A Randomized, Controlled Clinical Trial of  Chloroquine as Chemoprophylaxis or Intermittent Preventive Therapy to Prevent Malaria in Pregnancy in Malawi. Lancet Inf Dis. 2018 Sept 5.

Buchwald AG, Sixpence A, Chimenya M, Damson M, Sorkin JD, Wilson ML, Seydel K, Hochman S, Mathanga DP, Taylor TE, Laufer MK. Clinical implications of asymptomatic Plasmodium falciparum infection in Malawi. Clin Infect Dis 2018 May 16.

Cohee LM, Chilombe M, Ngwira A, Jemu SK, Mathanga DP, Laufer MK. Pilot Study of the Addition of Mass Treatment for Malaria to Existing School-Based Programs to Treat Neglected Tropical Diseases. Am J Trop Med Hyg Jan 2018:98(1):95-99

Boudova S, Divala TH, Mungwira R, Mawindo P, Tomoka T, Laufer MK. Placental but not peripheral Plasmodium falciparum infection during pregnancy is associated with increased risk of malaria in infancy. J Infect Dis. Sept 2017:216(6):732-735

Divala TH, Mungwira RG, Laufer MK. Moving targets: The challenges of studying infectious diseases among pregnant women in resource limited settings. Vaccine. Nov 25;33(47):6401-5, 2015. PMC4920047.

Walldorf JA, Cohee LM, Coalson JE, Bauleni A, Nkanaunena K, Kapito-Tembo A, Seydel KB, Ali D, Mathanga D, Taylor TE, Valim C, Laufer MK. School-Age Children Are a Reservoir of Malaria Infection in Malawi. PLoS One Jul 24;10(7):e0134061, 2014. PMC4514805.

Laufer MK, Thesing PC, Eddington ND, Masonga R, Dzinjalamala FK, Takala SL, Taylor TE, Plowe CV. Return of chloroquine antimalarial efficacy in Malawi. New England Journal of Medicine 255:1959-1966, 2006. PMID 17093247.

View a complete list of Dr. Laufer’s publications 

Awards and Affiliations

Joseph Augustine LePrince, American Society of Tropical Medicine and Hygiene.  Inrecognition of outstanding work in the field of malariology.

J. Tyson Tildon Award for Pediatric Research, University of Maryland School of Medicine

Alpha Omega Alpha

Teaching Commendation, Host Defenses and Infectious Diseases

Global Health Faculty Award, Center for Global Health Initiatives, University of Maryland, Baltimore

Grants and Contracts

(Selected federal grants)

“Interdisciplinary malaria research training in Malawi” (Principal Investigator) NIH D43TW010075

“Mentoring and patient-oriented research in malaria” (Principal Investigator) NIH K24AI114996

“Randomized, open-label controlled trial of daily trimethoprim-sulfamethoxazole or weekly chloroquine among adults on antiretroviral therapy in Blantyre, Malawi” (Principal Investigator) NIH U01AI089342

“Determinants of Malaria Disease in Malawi, International Center of Excellence for Malaria Research” (Project Leader) NIH U19AI089683

“Impact of in utero HIV exposure on infant T and B cell responses in Malawi” (Co-Principal Investigator) NIH U01HD092308

In the News

Professional Activity

America Society of Tropical Medicine and Hygiene: Board of Directors, Program Committee

Pediatric Infectious Diseases Society: International Affairs Committee

American Journal of Tropical Medicine and Hygiene: Section Editor

American Society of Microbiology: Microbe Planning Committee