Academic Title:
Assistant Professor
Primary Appointment:
Medicine
Location:
HSF III Ofc 7174
Phone (Primary):
(410) 706-1253
Education and Training
Undergraduate: Wake Forest University, B.S. in Chemistry & B.A. in German, 2010
Graduate: University of California Santa Barbara, Ph.D. in Chemistry 2017
Postdoctoral Fellowship: University of Pittsburgh, Vascular Medicine Institute, T32 Training in Translational Research in Vascular Biology, 2022
Research/Clinical Keywords
nitric oxide, carbon monoxide poisoning, hemoproteins, thiols, kinetics, bioinorganic chemistry
Highlighted Publications
DeMartino AW, Poudel L, Dent MR, Chen X, Xu Q, Gladwin BS, Tejero J, Basu S, Alipour E, Jiang Y, Rose JJ, Gladwin MT, Kim-Shapiro DB. "Thiol-catalyzed formation of NO-ferroheme regulates intravascular NO signaling." Nat Chem Biol (2023). DOI: 10.1038/s41589-023-01413-3
DeMartino AW, Amdahl MB, Bocian KA et al. “Tunable redox sensor properties of human cytoglobin allosterically regulate heme pocket reactivity.” Free Radical Bio Med (2021), 162, 423-434. DOI: 1016/j.freeradbiomed.2020.10.321
Xu Q, Rose JJ, Chen X, DeMartino AW, et al. “Cell-free and alkylated hemoproteins improve survival in mouse models of carbon monoxide poisoning.” JCI Insight 2022), 7 (21), e153296. DOI: 10.1172/jci.insight.153296
DeMartino AW, Rose JJ, Amdahl MA et al. “No evidence of hemoglobin damage by SARS-CoV-2 infection.” Haematologica (2020), 105 (12), 2769-2773. DOI: 3324/haematol.2020.264267
DeMartino AW, Kim-Shapiro D, Patel R, Gladwin MT. “Nitrite and nitrate chemical biology and signalling.” Bri J Pharmacol (2019), 176 (2), 228-245. DOI: 1111/bph.14484