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Anthony W. DeMartino, PhD

Academic Title:

Assistant Professor

Primary Appointment:

Medicine

Location:

HSF III Ofc 7174

Phone (Primary):

(410) 706-1253

Education and Training

Undergraduate: Wake Forest University, B.S. in Chemistry & B.A. in German, 2010

Graduate: University of California Santa Barbara, Ph.D. in Chemistry 2017

Postdoctoral Fellowship: University of Pittsburgh, Vascular Medicine Institute, T32 Training in Translational Research in Vascular Biology, 2022 

Research/Clinical Keywords

nitric oxide, carbon monoxide poisoning, hemoproteins, thiols, kinetics, bioinorganic chemistry

Highlighted Publications

DeMartino AW, Poudel L, Dent MR, Chen X, Xu Q, Gladwin BS, Tejero J, Basu S, Alipour E, Jiang Y, Rose JJ, Gladwin MT, Kim-Shapiro DB. "Thiol-catalyzed formation of NO-ferroheme regulates intravascular NO signaling." Nat Chem Biol (2023). DOI: 10.1038/s41589-023-01413-3 

DeMartino AW, Amdahl MB, Bocian KA et al. “Tunable redox sensor properties of human cytoglobin allosterically regulate heme pocket reactivity.” Free Radical Bio Med (2021), 162, 423-434. DOI: 1016/j.freeradbiomed.2020.10.321

Xu Q, Rose JJ, Chen X, DeMartino AW, et al. “Cell-free and alkylated hemoproteins improve survival in mouse models of carbon monoxide poisoning.” JCI Insight 2022), 7 (21), e153296. DOI: 10.1172/jci.insight.153296

DeMartino AW, Rose JJ, Amdahl MA et al. “No evidence of hemoglobin damage by SARS-CoV-2 infection.” Haematologica (2020), 105 (12), 2769-2773. DOI: 3324/haematol.2020.264267

DeMartino AW, Kim-Shapiro D, Patel R, Gladwin MT. “Nitrite and nitrate chemical biology and signalling.” Bri J Pharmacol (2019), 176 (2), 228-245. DOI: 1111/bph.14484