Shuo Chen, PhD

Ph.D, Biostatistics  Emory University,   2012

Master of Science in Public Health, Emory University

Master of Science, Mathematics and Statistics, East Tennessee State University   

Bachelor of Science, Electrical Engineering, Harbin Institute of Technology, Harbin, China  

Dr. Chen is a biostatistician with a research focus on modeling large biomedical data with complex and organized structures. For example, he develops methods modeling the spatiotemporal dependence in imaging data, linkage disequilibrium in genetics data, co-expression graph structure in omics data, and inference for edges in group-level graphs. Besides population-level statistical inference, he is also interested in individual-level inference by developing novel machine learning models that take into account the complex and organized dependence patterns between high-throughput features. Dr. Chen also has extensive experience in biostatistical collaborative research including clinical trial design and analysis, environmental health, infectious disease, and cancer research. 

Lab website: https://www.umdbright.com/

Big Data, machine learning, clinical trial design/analysis, network/graph statistics, neuroimaging statistics (MRI, EEG, fMRI, MRS, and DTI data), genomics and proteomics, Bayesian modeling, optimization.

# the corresponding author;

$  trainees and advisees of Chen

1. Wu Q^$, Huang, X., Culbreth, A., Waltz, J., Hong, L. E., & Chen, S^# (2021+). Extracting Brain Disease-Related Connectome Subgraphs by Adaptive Dense Subgraph Discovery. Biometrics, in press.
2.  Ge, Y.^$, Hare, S., Chen, G., Waltz, J. A., Kochunov, P., Elliot Hong, L., & Chen, S^#. (2021+)Bayes estimate of primary threshold in clusterwise functional magnetic resonance imaging inferences. Statistics in Medicine. in press
3. Wang J$, Kochunov P, Sampath H, Hatch KS, Ryan MC, Xue F, Neda J, Paul T, Hahn B, Gold J, Waltz J, Hong LE, Chen, S^#. White matter brain aging in relationship to schizophrenia and its cognitive deficit. Schizophr Res. 2021 Mar 2;230:9-16. doi: 10.1016/j.schres.2021.02.003. [Epub ahead of print] PubMed PMID: 33667860. in press
4. Wu Q^$, Zhang Z, Ma T, Waltz J, Milton D, Chen, S^#. (2021+) Link Predictions for Incomplete Network Data with Outcome Misclassification, Statistics in Medicine. in press
5. Wu Q^$, Ma T, Liu Q, Milton D, Zhang Y, Chen, S^#. (2021+) Extracting Interconnected Communities in Gene Co-expression Networks. Bioinformatics. in press.
6.  Chen, S^#., Bowman, FD., Xing, Y^$.,  (2020). Detecting and Testing Altered Brain Connectivity Networks with K-partite Network Topology.   Computational Statistics and Data Analysis, 141, 109-122
7. Chen, S^#., Xing, Y^$., Kang, J.,  Kochunov P., Hong, E.L. (2020). Bayesian Modeling of Dependence in Brain Connectivity Data.   Biostatistics, 21 (2), 269-286
8.  Chen, S^#., Kang, J., Xing, Y^$., Zhao, Y., Milton, D. (2018). Estimating Large Covariance Matrix with Network Topology for High-dimensional Biomedical Data.   Computational Statistics and Data Analysis,  127, 82-95.
9. Chen S^#,  Bowman  F.D.,  and  Mayberg  H.  (2016).   A Bayesian  Hierarchical  Framework  for Modeling  Brain Connectivity for Neuroimaging  Data,  Biometrics, 72. 2.  . DOI: 10.1111/biom.12433
10. Chen S^#,  Kang J, Xing Y^$, and Wang G^$,  (2015). A parsimonious statistical method to detect group-wise differentially expressed functional connectivity networks,  Human Brain Mapping, 36(12), 5196-5206. DOI: 10.1002/hbm.23007